DSC was used to study the effects of predeformation on the reverse martensitic transformation of near-equiatomic TiNi alloy. Both the start temperature As and the finish temperature Af of the reverse transformation in...DSC was used to study the effects of predeformation on the reverse martensitic transformation of near-equiatomic TiNi alloy. Both the start temperature As and the finish temperature Af of the reverse transformation increased with increasing degree of predeformation, but the algebraic difference between As and Af decreased with increasing predeformation until it reached a minimum value, then remained unchanged with further deformation. Transformation heat also increased with increasing predeformation until it reached a maximum value, then decreased with further predeformation. All the phenomena above were considered to be closely related with the release of elastic strain energy during predeformation.展开更多
Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide respons...Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide response range remains a challenge.Inspired by human skin,we select commercial silicon carbide sandpaper as a template to fabricate carbon nanotube(CNT)/polydimethylsiloxane(PDMS)composite film with a hierarchical structured surface(h-CNT/PDMS)through solution blending and blade coating and then assemble the h-CNT/PDMS composite film with interdigitated electrodes and polyurethane(PU)scotch tape to obtain an h-CNT/PDMS-based flexible pressure sensor.Based on in-situ optical images and finite element analysis,the significant compressive contact effect between the hierarchical structured surface of h-CNT/PDMS and the interdigitated electrode leads to enhanced pressure sensitivity and a wider response range(0.1661 kPa^(-1),0.4574 kPa^(-1)and 0.0989 kPa^(-1)in the pressure range of 0–18 kPa,18–133 kPa and 133–300 kPa)compared with planar CNT/PDMS composite film(0.0066 kPa^(-1)in the pressure range of 0–240 kPa).The prepared pressure sensor displays rapid response/recovery time,excellent stability,durability,and stable response to different loading modes(bending and torsion).In addition,our pressure sensor can be utilized to accurately monitor and discriminate various stimuli ranging from human motions to pressure magnitude and spatial distribution.This study supplies important guidance for the fabrication of flexible pressure sensors with superior sensing performance in next-generation wearable electronic devices.展开更多
With the rapid development of wearable intelligent devices,low-cost wearable strain sensors with high sensitivity and low detection limit are urgently demanded.Meanwhile,sensing stability of sensor in wet or corrosive...With the rapid development of wearable intelligent devices,low-cost wearable strain sensors with high sensitivity and low detection limit are urgently demanded.Meanwhile,sensing stability of sensor in wet or corrosive environments should also be considered in practical applications.Here,superhydrophobic microcracked conductive paper-based strain sensor was fabricated by coating conductive Ti_(3)C_(2)T_(x) MXene on printing paper via dip-coating process and followed by depositing superhydrophobic candle soot layer on its surface.Owing to the ultrasensitive microcrack structure in the conductive coating layer induced by the mismatch of elastic modulus and thermal expansion coefficient between conductive coating layer and paper substrate during the drying process,the prepared paper-based strain sensor exhibited a high sensitivity(gauge factor,GF=17.4)in the strain range of 0–0.6%,ultralow detection limit(0.1%strain)and good fatigue resistance over 1000 cycles towards bending deformation.Interestingly,it was also applicable for torsion deformation detection,showing excellent torsion angle dependent,repeatable and stable sensing performances.Meanwhile,it displayed brilliant waterproof,self-cleaning and corrosion-resistant properties due to the existence of micro/nano-structured and the low surface energy candle soot layer.As a result,the prepared paper-based strain sensor can effectively monitor a series of large-scale and small-scale human motions even under water environment,showing the great promising in practical harsh outdoor environments.Importantly,it also demonstrated good applicability for spatial strain distribution detection of skin upon body movement when assembled into electronic-skin(E-skin).This study will provide great guidance for the design of next generation wearable strain sensor.展开更多
Dear Editor,Myocardial injury following ischemia/reperfusion(I/R)is a common clinical scenario in patients suffering from ischemic heart disease(Hausenloy et al.,2016).The involvement of proteins and signaling pathway...Dear Editor,Myocardial injury following ischemia/reperfusion(I/R)is a common clinical scenario in patients suffering from ischemic heart disease(Hausenloy et al.,2016).The involvement of proteins and signaling pathways is well studied in myocardial I/R injury and protection(Hausenloy et al.,2016;Yang et al.,2012),however,more than 98%of the transcriptional output in mammals are noncoding RNAs(ncRNAs).These products range from short microRNAs(miRNAs)to long noncoding RNAs(lncRNAs,Das et al.,2018)and modulate critical pathophysiologic mechanisms,such as apoptosis,oxidative stress,Ca2+overload and inflammation,during myocardial I/R injury and protection(Das et al.,2018).展开更多
Regulation of cell behaviors and even cell fates is of great significance in diverse biomedical applications such as cancer treatment,cell-based therapy,and tissue engineering.During the past decades,diverse methods h...Regulation of cell behaviors and even cell fates is of great significance in diverse biomedical applications such as cancer treatment,cell-based therapy,and tissue engineering.During the past decades,diverse methods have been developed to regulate cell behaviors such as applying external stimuli,delivering exogenous molecules into cell interior and changing the physicochemical properties of the substrates where cells adhere.Photothermal scaffolds/surfaces refer to a kind of materials embedded or coated with photothermal agents that can absorb light with proper wavelength(usually in near infrared region)and convert light energy to heat;the generated heat shows great potential for regulation of cell behaviors in different ways.In the current review,we summarize the recent research progress,especially over the past decade,of using photothermal scaffolds/surfaces to regulate cell behaviors,which could be further categorized into three types:(i)killing the tumor cells via hyperthermia or thermal ablation,(ii)engineering cells by intracellular delivery of exogenous molecules via photothermal poration of cell membranes,and(iii)releasing a single cell or an intact cell sheet via modulation of surface physicochemical properties in response to heat.In the end,challenges and perspectives in these areas are commented.展开更多
基金the National Natural Science Foundation of China under grant No. 59601004,59731030.
文摘DSC was used to study the effects of predeformation on the reverse martensitic transformation of near-equiatomic TiNi alloy. Both the start temperature As and the finish temperature Af of the reverse transformation increased with increasing degree of predeformation, but the algebraic difference between As and Af decreased with increasing predeformation until it reached a minimum value, then remained unchanged with further deformation. Transformation heat also increased with increasing predeformation until it reached a maximum value, then decreased with further predeformation. All the phenomena above were considered to be closely related with the release of elastic strain energy during predeformation.
基金supported by the National Natural Science Foundation of China(NO:51803191,12072325,52103100)the National Key R&D Program of China(2019YFA0706802)+1 种基金the 111 project(D18023)the Key Scientific and Technological Project of Henan Province(202102210038).
文摘Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide response range remains a challenge.Inspired by human skin,we select commercial silicon carbide sandpaper as a template to fabricate carbon nanotube(CNT)/polydimethylsiloxane(PDMS)composite film with a hierarchical structured surface(h-CNT/PDMS)through solution blending and blade coating and then assemble the h-CNT/PDMS composite film with interdigitated electrodes and polyurethane(PU)scotch tape to obtain an h-CNT/PDMS-based flexible pressure sensor.Based on in-situ optical images and finite element analysis,the significant compressive contact effect between the hierarchical structured surface of h-CNT/PDMS and the interdigitated electrode leads to enhanced pressure sensitivity and a wider response range(0.1661 kPa^(-1),0.4574 kPa^(-1)and 0.0989 kPa^(-1)in the pressure range of 0–18 kPa,18–133 kPa and 133–300 kPa)compared with planar CNT/PDMS composite film(0.0066 kPa^(-1)in the pressure range of 0–240 kPa).The prepared pressure sensor displays rapid response/recovery time,excellent stability,durability,and stable response to different loading modes(bending and torsion).In addition,our pressure sensor can be utilized to accurately monitor and discriminate various stimuli ranging from human motions to pressure magnitude and spatial distribution.This study supplies important guidance for the fabrication of flexible pressure sensors with superior sensing performance in next-generation wearable electronic devices.
基金supported by the National Natural Science Foundation of China(51803191,12072325)the National Key R&D Program of China(2019YFA0706802)+2 种基金the 111 project(D18023)Key Scientific and Technological Project of Henan Province(202102210038)Major projects of Ningbo。
文摘With the rapid development of wearable intelligent devices,low-cost wearable strain sensors with high sensitivity and low detection limit are urgently demanded.Meanwhile,sensing stability of sensor in wet or corrosive environments should also be considered in practical applications.Here,superhydrophobic microcracked conductive paper-based strain sensor was fabricated by coating conductive Ti_(3)C_(2)T_(x) MXene on printing paper via dip-coating process and followed by depositing superhydrophobic candle soot layer on its surface.Owing to the ultrasensitive microcrack structure in the conductive coating layer induced by the mismatch of elastic modulus and thermal expansion coefficient between conductive coating layer and paper substrate during the drying process,the prepared paper-based strain sensor exhibited a high sensitivity(gauge factor,GF=17.4)in the strain range of 0–0.6%,ultralow detection limit(0.1%strain)and good fatigue resistance over 1000 cycles towards bending deformation.Interestingly,it was also applicable for torsion deformation detection,showing excellent torsion angle dependent,repeatable and stable sensing performances.Meanwhile,it displayed brilliant waterproof,self-cleaning and corrosion-resistant properties due to the existence of micro/nano-structured and the low surface energy candle soot layer.As a result,the prepared paper-based strain sensor can effectively monitor a series of large-scale and small-scale human motions even under water environment,showing the great promising in practical harsh outdoor environments.Importantly,it also demonstrated good applicability for spatial strain distribution detection of skin upon body movement when assembled into electronic-skin(E-skin).This study will provide great guidance for the design of next generation wearable strain sensor.
基金supported by the National Natural Science Foundation of China (81770402)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16010201)National Key R&D Program of China (2017YFA 0103700, 2016YFC1301204)
文摘Dear Editor,Myocardial injury following ischemia/reperfusion(I/R)is a common clinical scenario in patients suffering from ischemic heart disease(Hausenloy et al.,2016).The involvement of proteins and signaling pathways is well studied in myocardial I/R injury and protection(Hausenloy et al.,2016;Yang et al.,2012),however,more than 98%of the transcriptional output in mammals are noncoding RNAs(ncRNAs).These products range from short microRNAs(miRNAs)to long noncoding RNAs(lncRNAs,Das et al.,2018)and modulate critical pathophysiologic mechanisms,such as apoptosis,oxidative stress,Ca2+overload and inflammation,during myocardial I/R injury and protection(Das et al.,2018).
基金supported by the National Natural Science Foundation of China(21774086 and 81671742)the Natural Science Foundation of Jiangsu Province(BK20180093)+1 种基金the Suzhou Municipal Science and Technology Foundation(SYS2018026)the Start-Up Grant of Jining Medical University(600910001).
文摘Regulation of cell behaviors and even cell fates is of great significance in diverse biomedical applications such as cancer treatment,cell-based therapy,and tissue engineering.During the past decades,diverse methods have been developed to regulate cell behaviors such as applying external stimuli,delivering exogenous molecules into cell interior and changing the physicochemical properties of the substrates where cells adhere.Photothermal scaffolds/surfaces refer to a kind of materials embedded or coated with photothermal agents that can absorb light with proper wavelength(usually in near infrared region)and convert light energy to heat;the generated heat shows great potential for regulation of cell behaviors in different ways.In the current review,we summarize the recent research progress,especially over the past decade,of using photothermal scaffolds/surfaces to regulate cell behaviors,which could be further categorized into three types:(i)killing the tumor cells via hyperthermia or thermal ablation,(ii)engineering cells by intracellular delivery of exogenous molecules via photothermal poration of cell membranes,and(iii)releasing a single cell or an intact cell sheet via modulation of surface physicochemical properties in response to heat.In the end,challenges and perspectives in these areas are commented.
