The outbreak of respiratory diseases,such as COVID-19 and influenza,has drawn global attention.However,it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infectio...The outbreak of respiratory diseases,such as COVID-19 and influenza,has drawn global attention.However,it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection.In this study,we conducted a test-negative case-control study,and utilized a logistic regression model to analyze the relationship between SARS-CoV-2 and influenza A infections.Among 258 eligible patient samples with influenza-like illness(ILI),we did not detect a statistically significant association between the history of SARS-CoV-2 infection and the risk of influenza A infection.These findings might indicate that antibodies against COVID-19 acquired through vaccination or natural immunity have not protected against influenza.展开更多
基金supported in part by non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(Grant No.:2020-PT330-003)the youth science and technology innovation talent of Tianshan Talent Training Program in Xinjiang(Grant No.:2022TSYCCX0099)+3 种基金major science and technology projects of Xinjiang Uygur Autonomous Region(Grant No.:2020A03004-3)the 14-th Five-Year Plan Distinctive Program of Public Health and Preventive Medicine in Higher Education Institutions of Xinjiang Uygur Autonomous Region,Chinasupported by the National Natural Science Foundation of China(Grant No.:12401648)Tianjin Medical University start-up funding(Grant No.:116003-DW010046)。
文摘The outbreak of respiratory diseases,such as COVID-19 and influenza,has drawn global attention.However,it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection.In this study,we conducted a test-negative case-control study,and utilized a logistic regression model to analyze the relationship between SARS-CoV-2 and influenza A infections.Among 258 eligible patient samples with influenza-like illness(ILI),we did not detect a statistically significant association between the history of SARS-CoV-2 infection and the risk of influenza A infection.These findings might indicate that antibodies against COVID-19 acquired through vaccination or natural immunity have not protected against influenza.