目的:大鼠坐骨神经离断损伤后神经缝合,观察桥接导管移植骨髓间质干细胞(Bone marrow mesenchymal stem cells,BMSC)的治疗效果。方法:大鼠右侧坐骨神经离断损伤模型,按手术方式分为单纯缝合组、假手术组、对照组和干细胞组,单纯缝合组...目的:大鼠坐骨神经离断损伤后神经缝合,观察桥接导管移植骨髓间质干细胞(Bone marrow mesenchymal stem cells,BMSC)的治疗效果。方法:大鼠右侧坐骨神经离断损伤模型,按手术方式分为单纯缝合组、假手术组、对照组和干细胞组,单纯缝合组参考文献造模,造模成功后进行已经离断的坐骨神经原位缝合,同时每只大鼠左侧坐骨神经未进行任何操作为对照组,干细胞组在缝合神经的基础上进行导管桥接,同时在导管周围进行干细胞移植,假手术组只切开皮肤切口然后缝合,不损伤坐骨神经,观察4组大鼠的坐骨神经功能指数、大鼠同侧坐骨神经支配的三头肌湿重恢复率、坐骨神经传导速度等指标。结果:大鼠坐骨神经功能(SFI)显示,单纯缝合组和干细胞组SFI低于假手术组与健康对照组( P <0.05),三头肌湿重恢复率显示假手术组与健康对照组高于干细胞组与单纯缝合组( P <0.05);离体坐骨神经传导速度检测显示假手术组与健康对照组高于其它两组( P <0.05),但单纯缝合组与干细胞组之间比较差异无统计学意义( P >0.05)。结论:坐骨神经离断损伤治疗中进行同种干细胞移植具有治疗效果,但作用不明显。展开更多
Discussed in this paper was the pre-processing procedure for gravity data, including topographical correction,intermediary layer correction etc. The necessity to utilize aerial photogram to do topographical correction...Discussed in this paper was the pre-processing procedure for gravity data, including topographical correction,intermediary layer correction etc. The necessity to utilize aerial photogram to do topographical correction in middle area was discussed, and a real examples given showing the effect. We discussed the problems caused by the maximum radius for conventional correction, the necessity of extending the radius for topographical correction, the corresponding method for calculation of topographical correction, and the standard of optimally selecting the radium for topographical correction.This method could raise the data accuracy of gravity survey in the complex mountainous areas by several millil-gals-several tens milli-gals reaching the exploration effect as well as in plain area almost.展开更多
文摘目的:大鼠坐骨神经离断损伤后神经缝合,观察桥接导管移植骨髓间质干细胞(Bone marrow mesenchymal stem cells,BMSC)的治疗效果。方法:大鼠右侧坐骨神经离断损伤模型,按手术方式分为单纯缝合组、假手术组、对照组和干细胞组,单纯缝合组参考文献造模,造模成功后进行已经离断的坐骨神经原位缝合,同时每只大鼠左侧坐骨神经未进行任何操作为对照组,干细胞组在缝合神经的基础上进行导管桥接,同时在导管周围进行干细胞移植,假手术组只切开皮肤切口然后缝合,不损伤坐骨神经,观察4组大鼠的坐骨神经功能指数、大鼠同侧坐骨神经支配的三头肌湿重恢复率、坐骨神经传导速度等指标。结果:大鼠坐骨神经功能(SFI)显示,单纯缝合组和干细胞组SFI低于假手术组与健康对照组( P <0.05),三头肌湿重恢复率显示假手术组与健康对照组高于干细胞组与单纯缝合组( P <0.05);离体坐骨神经传导速度检测显示假手术组与健康对照组高于其它两组( P <0.05),但单纯缝合组与干细胞组之间比较差异无统计学意义( P >0.05)。结论:坐骨神经离断损伤治疗中进行同种干细胞移植具有治疗效果,但作用不明显。
文摘Discussed in this paper was the pre-processing procedure for gravity data, including topographical correction,intermediary layer correction etc. The necessity to utilize aerial photogram to do topographical correction in middle area was discussed, and a real examples given showing the effect. We discussed the problems caused by the maximum radius for conventional correction, the necessity of extending the radius for topographical correction, the corresponding method for calculation of topographical correction, and the standard of optimally selecting the radium for topographical correction.This method could raise the data accuracy of gravity survey in the complex mountainous areas by several millil-gals-several tens milli-gals reaching the exploration effect as well as in plain area almost.