Objective: To investigate the influence of the new coronavirus epidemic on tumor radiotherapy patients in Zigong City, and provide radiotherapy feasibility and safety in other prefecture-level or low-risk areas. Metho...Objective: To investigate the influence of the new coronavirus epidemic on tumor radiotherapy patients in Zigong City, and provide radiotherapy feasibility and safety in other prefecture-level or low-risk areas. Methods: Retrospective Collection of data from January 31, 2020, in our hospital, this time period is an epidemic group. The control group was data from January 31, 2019-May 31, in our hospital. Patient data includes gender, age, tumor type, hospitalization fee, average hospitalization day, radiotherapy completion, treatment destination, and other information. Results: The patients with epidemic groups and control groups were 320 and 237, respectively, and the radiotherapy patients increased by 25.9%, increasing patients mainly from other departures outside the tumor department underperformance reform intervention. The epidemic group of brain and breast tumor patients were 39 and 37, respectively, with statistical differences (P < 0.05) compared to the control group (25 and 16 respectively). The number of tumor radiotherapy patients in other parts increased, but there was no statistical difference (P > 0.05). Inpatient costs, the average hospitalization day, radiotherapy completion, the purpose of treatment, and other data epidemic groups and control groups have no statistical difference (P > 0.05). Conclusion: The number of COVID-2019 epidemic interventions has increased the number of cancer radiotherapy patients in our hospital, and the epidemic situation has no effect on hospitalization, the average hospitalization day, radiotherapy, and the like. Optimizing the process of clinical treatment, strict prevention and control measures can ensure timely and safe radiotherapy in low-risk areas.展开更多
Biochar as an emerging carbonaceous material has exhibited a great potential in environmental application for its perfect adsorption ability.However,there are abundant persistent free radicals(PFRs)in biochar,so the d...Biochar as an emerging carbonaceous material has exhibited a great potential in environmental application for its perfect adsorption ability.However,there are abundant persistent free radicals(PFRs)in biochar,so the direct and indirect PFRs-mediated removal of organic and inorganic contaminants by biochar was widely reported.In order to comprehend deeply the formation of PFRs in biochar and their interactions with contaminants,this paper reviews the formation mechanisms of PFRs in biochar and the PFRs-mediated environmental applications of biochar in recent years.Finally,future challenges in this field are also proposed.This review provides a more comprehensive understanding on the emerging applications of biochar from the viewpoint of the catalytic role of PFRs.展开更多
<strong>Purpose:</strong> To investigate how much dose discrepancy would be caused by the anatomy changes during the radiotherapy (RT) course. <strong>Methods:</strong> Ten cervical cancer and ...<strong>Purpose:</strong> To investigate how much dose discrepancy would be caused by the anatomy changes during the radiotherapy (RT) course. <strong>Methods:</strong> Ten cervical cancer and ten nasopharyngeal carcinoma (NPC) CT datasets from RT patients were enrolled. The body contour from different directions changed to simulate the weight loss or gain for cervical cancer patients, who had been treated with external-beam RT using intensity-modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT). Moreover, the body contour from facial and shoulder superior-inferior positional change had been also assessed for NPC patients using IMRT or VMAT. The new CT (n-CT) was generated by the body contour changes with different directions based on original CT datasets. The dosimetric parameters to target volumes and organs at risk (OARs) were evaluated in Eclipse based on n-CT. <strong>Results:</strong> The target volumes and OARs were influenced by the body contour changes. Body contour expansion resulted in coverage loss, whereas body contour shrinkage increased the dose to the OARs. These findings were generally consistent for both IMRT and VMAT plans. Over a course of research, the dose to 95% of the target volumes for cervical cancer decreased by up to 2.83% per cm for IMRT and 2.87% per cm for VMAT (P < 0.05). And the influence on H&N plans was that the dose to 95% of the target volumes (low risk regions) decreased by up to 4.45% per cm. <strong>Conclusions:</strong> The RT staff could determine whether resimulation and replaning or not according to which body contour directions were changed.展开更多
Controlling pollution from per-and polyfluoroalkyl substances(PFAS)is a global challenge due to their toxicity,chemical stability and environmental persistence.Persulfate-based advanced oxidation processes(PS-AOPs)hav...Controlling pollution from per-and polyfluoroalkyl substances(PFAS)is a global challenge due to their toxicity,chemical stability and environmental persistence.Persulfate-based advanced oxidation processes(PS-AOPs)have emerged as a promising technology for degrading these persistent contaminants.However,the distinct physicochemical properties of PFAS lead to significant differences in the efficacy and mechanisms of PS-AOPs for PFAS removal,necessitating in-depth classification studies.This review critically examines the environmental fate and accumulation patterns of PFAS,focusing on PS-AOPs as a viable remediation strategy.Key contributions include:1)Sorting out the migration and transformation patterns of PFAS in the environment;2)Demonstration of PSAOP’s superiority over the advanced reduction process(ARP)for PFAS degradation;3)A systematic analysis of recent advancements in various PS-AOPs,encompassing their mechanisms,influencing factors,and system characteristics;4)An in-depth evaluation of how PFAS structure,particularly chain length and functional groups,affects degradation efficiency;5)Three integrated AOPs/ARPs strategies providing actionable insights to address PFAS contamination.Collectively,this review offers actionable insights for optimizing AOPs and ARPs,with implications for advancing PFAS remediation technologies.展开更多
文摘Objective: To investigate the influence of the new coronavirus epidemic on tumor radiotherapy patients in Zigong City, and provide radiotherapy feasibility and safety in other prefecture-level or low-risk areas. Methods: Retrospective Collection of data from January 31, 2020, in our hospital, this time period is an epidemic group. The control group was data from January 31, 2019-May 31, in our hospital. Patient data includes gender, age, tumor type, hospitalization fee, average hospitalization day, radiotherapy completion, treatment destination, and other information. Results: The patients with epidemic groups and control groups were 320 and 237, respectively, and the radiotherapy patients increased by 25.9%, increasing patients mainly from other departures outside the tumor department underperformance reform intervention. The epidemic group of brain and breast tumor patients were 39 and 37, respectively, with statistical differences (P < 0.05) compared to the control group (25 and 16 respectively). The number of tumor radiotherapy patients in other parts increased, but there was no statistical difference (P > 0.05). Inpatient costs, the average hospitalization day, radiotherapy completion, the purpose of treatment, and other data epidemic groups and control groups have no statistical difference (P > 0.05). Conclusion: The number of COVID-2019 epidemic interventions has increased the number of cancer radiotherapy patients in our hospital, and the epidemic situation has no effect on hospitalization, the average hospitalization day, radiotherapy, and the like. Optimizing the process of clinical treatment, strict prevention and control measures can ensure timely and safe radiotherapy in low-risk areas.
基金supported by the National Natural Science Foundation of China(No.52000013)the Scientific Research Foundation of Hunan Provincial Education Department,China(No.18B415,18B406 and 18A378)+1 种基金the Natural Science Foundation of Hunan Province,China(No.2020JJ4643)the training program for Excellent Yong Innovators of Changsha(No.kq1802022)。
文摘Biochar as an emerging carbonaceous material has exhibited a great potential in environmental application for its perfect adsorption ability.However,there are abundant persistent free radicals(PFRs)in biochar,so the direct and indirect PFRs-mediated removal of organic and inorganic contaminants by biochar was widely reported.In order to comprehend deeply the formation of PFRs in biochar and their interactions with contaminants,this paper reviews the formation mechanisms of PFRs in biochar and the PFRs-mediated environmental applications of biochar in recent years.Finally,future challenges in this field are also proposed.This review provides a more comprehensive understanding on the emerging applications of biochar from the viewpoint of the catalytic role of PFRs.
文摘<strong>Purpose:</strong> To investigate how much dose discrepancy would be caused by the anatomy changes during the radiotherapy (RT) course. <strong>Methods:</strong> Ten cervical cancer and ten nasopharyngeal carcinoma (NPC) CT datasets from RT patients were enrolled. The body contour from different directions changed to simulate the weight loss or gain for cervical cancer patients, who had been treated with external-beam RT using intensity-modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT). Moreover, the body contour from facial and shoulder superior-inferior positional change had been also assessed for NPC patients using IMRT or VMAT. The new CT (n-CT) was generated by the body contour changes with different directions based on original CT datasets. The dosimetric parameters to target volumes and organs at risk (OARs) were evaluated in Eclipse based on n-CT. <strong>Results:</strong> The target volumes and OARs were influenced by the body contour changes. Body contour expansion resulted in coverage loss, whereas body contour shrinkage increased the dose to the OARs. These findings were generally consistent for both IMRT and VMAT plans. Over a course of research, the dose to 95% of the target volumes for cervical cancer decreased by up to 2.83% per cm for IMRT and 2.87% per cm for VMAT (P < 0.05). And the influence on H&N plans was that the dose to 95% of the target volumes (low risk regions) decreased by up to 4.45% per cm. <strong>Conclusions:</strong> The RT staff could determine whether resimulation and replaning or not according to which body contour directions were changed.
基金supported by the National Natural Science Foundation of China(Nos.52200194,U22A20617,and U23A20665)the Natural Science Foundation of Hunan Province,China(No.2025JJ50254)the Fundamental Research Funds for the Central Universities,China(No.531118010976).
文摘Controlling pollution from per-and polyfluoroalkyl substances(PFAS)is a global challenge due to their toxicity,chemical stability and environmental persistence.Persulfate-based advanced oxidation processes(PS-AOPs)have emerged as a promising technology for degrading these persistent contaminants.However,the distinct physicochemical properties of PFAS lead to significant differences in the efficacy and mechanisms of PS-AOPs for PFAS removal,necessitating in-depth classification studies.This review critically examines the environmental fate and accumulation patterns of PFAS,focusing on PS-AOPs as a viable remediation strategy.Key contributions include:1)Sorting out the migration and transformation patterns of PFAS in the environment;2)Demonstration of PSAOP’s superiority over the advanced reduction process(ARP)for PFAS degradation;3)A systematic analysis of recent advancements in various PS-AOPs,encompassing their mechanisms,influencing factors,and system characteristics;4)An in-depth evaluation of how PFAS structure,particularly chain length and functional groups,affects degradation efficiency;5)Three integrated AOPs/ARPs strategies providing actionable insights to address PFAS contamination.Collectively,this review offers actionable insights for optimizing AOPs and ARPs,with implications for advancing PFAS remediation technologies.