目的分析北京地区秋冬季急性呼吸道感染的流行特征,为急性呼吸道感染疾病的防控和诊治提供依据。方法采用便利抽样法,以北京协和医院2023年9月—2024年2月因急性呼吸道感染就诊的患者为研究对象。采集患者鼻咽拭子标本,采用荧光定量PCR...目的分析北京地区秋冬季急性呼吸道感染的流行特征,为急性呼吸道感染疾病的防控和诊治提供依据。方法采用便利抽样法,以北京协和医院2023年9月—2024年2月因急性呼吸道感染就诊的患者为研究对象。采集患者鼻咽拭子标本,采用荧光定量PCR法检测6种常见呼吸道病原体[包括甲型流感病毒(influenza A virus,FluA)、乙型流感病毒(influenza B virus,FluB)、人鼻病毒(human rhinovirus,HRV)、肺炎支原体(Mycoplasma pneumoniae,MP)、呼吸道合胞病毒(respiratory syncytial virus,RSV)、腺病毒(adenovirus,ADV)]和新型冠状病毒感染情况,对病原体感染分布特征进行分析。结果共入选符合标准的患者5556例,6种常见呼吸道病原体总体阳性率为63.7%,单一病原体阳性率为54.0%,2种病原体阳性率为8.9%,3种及以上病原体阳性率为0.7%。整体检出病原体以FluA和RSV为主,阳性率依次为16.1%和15.7%;ADV、MP、HRV和FluB阳性率接近,分别为11.1%、11.1%、10.0%和10.0%。病原体总体阳性率在性别间无显著性差异,但在秋冬季节间(χ^(2)=34.617,P<0.001)以及儿童、中青年和老年患者间(χ^(2)=422.38,P<0.001)存在统计学差异。其中,MP(χ^(2)=8.647,P=0.003)、FluA(χ^(2)=131.932,P<0.001)和HRV(χ^(2)=174.199,P<0.001)在秋季的阳性率显著高于冬季,而FluB在冬季的阳性率显著高于秋季(χ^(2)=287.894,P<0.001);儿童组MP、RSV、HRV和ADV的阳性率均显著高于中青年和老年患者(P均<0.001),而FluB在中青年患者中的阳性率则显著高于儿童和老年患者(P均<0.001)。6种常见呼吸道病原体在新型冠状病毒感染流行时期阳性率明显下降,表现为非同步季节性模式。结论北京地区呼吸道病原体流行情况与年龄、季节有关,需在不同季节、针对不同重点人群开展有针对性的预防措施。展开更多
＂The ＇Longevity and Virtues＇ exhibition with the theme of birthday celebrations of the Qing Emperors and Empress Dowagers on the one hand shows how the Qing Dynasty celebrated birthdays of its Emperors and Empress ...＂The ＇Longevity and Virtues＇ exhibition with the theme of birthday celebrations of the Qing Emperors and Empress Dowagers on the one hand shows how the Qing Dynasty celebrated birthdays of its Emperors and Empress Dowagers as well as the respecting the elderly tradition, and reflects people＇s yearning for longevity on the other hand. As the old saying goes ＂Men can only live a long life in a spring- like world.＂ I profoundly expect Hong Kong SAR Government can honestly collaborate with all walks of life to make a better future for Hong Kong and enable every Hong Kong citizen to share the achievements of social prosperity and progress. I hope that every Hong Kong citizen can enjoy their twilight years in a society with goods in plentiful supply.展开更多
China's aerospace industry is facing a major task of increasing the reform of aerospace management system and speeding up civil-military integration, which leads to an urgent demand for new aerospace think tank pr...China's aerospace industry is facing a major task of increasing the reform of aerospace management system and speeding up civil-military integration, which leads to an urgent demand for new aerospace think tank products. Thankfully, with "information space" as the carrier, the "systems science" as the guidance, and QIAN Xuesen's "metasynthetic wisdom system" as the core, QIAN Xuesen think tank provides the decision support for China to develop an aerospace knowledge economy and to continuously enhance the "space soft power". In this paper, the framework of the meta-synthetic wisdom system guided by systems science is presented, the relationship between basic ideas of QIAN Xuesen think tank and meta-synthetic wisdom system is explained and the construction items of aerospace hall of the workshop for meta-synthetic engineering(aerospace HWMSE) are analyzed.展开更多
文摘目的分析北京地区秋冬季急性呼吸道感染的流行特征,为急性呼吸道感染疾病的防控和诊治提供依据。方法采用便利抽样法,以北京协和医院2023年9月—2024年2月因急性呼吸道感染就诊的患者为研究对象。采集患者鼻咽拭子标本,采用荧光定量PCR法检测6种常见呼吸道病原体[包括甲型流感病毒(influenza A virus,FluA)、乙型流感病毒(influenza B virus,FluB)、人鼻病毒(human rhinovirus,HRV)、肺炎支原体(Mycoplasma pneumoniae,MP)、呼吸道合胞病毒(respiratory syncytial virus,RSV)、腺病毒(adenovirus,ADV)]和新型冠状病毒感染情况,对病原体感染分布特征进行分析。结果共入选符合标准的患者5556例,6种常见呼吸道病原体总体阳性率为63.7%,单一病原体阳性率为54.0%,2种病原体阳性率为8.9%,3种及以上病原体阳性率为0.7%。整体检出病原体以FluA和RSV为主,阳性率依次为16.1%和15.7%;ADV、MP、HRV和FluB阳性率接近,分别为11.1%、11.1%、10.0%和10.0%。病原体总体阳性率在性别间无显著性差异,但在秋冬季节间(χ^(2)=34.617,P<0.001)以及儿童、中青年和老年患者间(χ^(2)=422.38,P<0.001)存在统计学差异。其中,MP(χ^(2)=8.647,P=0.003)、FluA(χ^(2)=131.932,P<0.001)和HRV(χ^(2)=174.199,P<0.001)在秋季的阳性率显著高于冬季,而FluB在冬季的阳性率显著高于秋季(χ^(2)=287.894,P<0.001);儿童组MP、RSV、HRV和ADV的阳性率均显著高于中青年和老年患者(P均<0.001),而FluB在中青年患者中的阳性率则显著高于儿童和老年患者(P均<0.001)。6种常见呼吸道病原体在新型冠状病毒感染流行时期阳性率明显下降,表现为非同步季节性模式。结论北京地区呼吸道病原体流行情况与年龄、季节有关,需在不同季节、针对不同重点人群开展有针对性的预防措施。
文摘＂The ＇Longevity and Virtues＇ exhibition with the theme of birthday celebrations of the Qing Emperors and Empress Dowagers on the one hand shows how the Qing Dynasty celebrated birthdays of its Emperors and Empress Dowagers as well as the respecting the elderly tradition, and reflects people＇s yearning for longevity on the other hand. As the old saying goes ＂Men can only live a long life in a spring- like world.＂ I profoundly expect Hong Kong SAR Government can honestly collaborate with all walks of life to make a better future for Hong Kong and enable every Hong Kong citizen to share the achievements of social prosperity and progress. I hope that every Hong Kong citizen can enjoy their twilight years in a society with goods in plentiful supply.
文摘China's aerospace industry is facing a major task of increasing the reform of aerospace management system and speeding up civil-military integration, which leads to an urgent demand for new aerospace think tank products. Thankfully, with "information space" as the carrier, the "systems science" as the guidance, and QIAN Xuesen's "metasynthetic wisdom system" as the core, QIAN Xuesen think tank provides the decision support for China to develop an aerospace knowledge economy and to continuously enhance the "space soft power". In this paper, the framework of the meta-synthetic wisdom system guided by systems science is presented, the relationship between basic ideas of QIAN Xuesen think tank and meta-synthetic wisdom system is explained and the construction items of aerospace hall of the workshop for meta-synthetic engineering(aerospace HWMSE) are analyzed.
