硒作为人体必需微量元素,在抗氧化、心血管保护、免疫增强及癌症预防等生理功能中具有关键作用。针对我国72%土壤缺硒的现状,通过作物施硒转化为有机硒是安全经济的补硒途径。本研究系统评估施硒对水稻、小麦、玉米的增产提质效应,为科...硒作为人体必需微量元素,在抗氧化、心血管保护、免疫增强及癌症预防等生理功能中具有关键作用。针对我国72%土壤缺硒的现状,通过作物施硒转化为有机硒是安全经济的补硒途径。本研究系统评估施硒对水稻、小麦、玉米的增产提质效应,为科学施硒提供理论依据。研究收集2013—2024年中国知网、维普、万方、Web of Science及PubMed数据库中134篇田间试验文献,以“硒”“小麦/玉米/水稻”“产量”为关键词,采用响应比自然对数(lnR)作为效应值进行Meta分析,借助Microsoft Office、Get Data Graph Digitizer、MetaWin 2.1等软件处理数据。施硒总体使水稻、小麦、玉米增产5.41%(95%CI:4.74%—6.08%,P_(Q)<0.01),其中小麦和水稻增产显著,分别提升8.72%(95%CI:7.69%—9.75%)和6.35%(95%CI:6.34%—7.71%),玉米增产不明显,效应值仅为0.46%(95%CI:-0.71%—1.63%)且lnR的95%置信区间下限小于0;施硒显著提升籽粒硒含量(164.09%,95%CI:156.15%—169.21%,P_(Q)<0.01),玉米提升效果最佳,效应值为172.97%(95%CI:164.55%—181.39%,P_(Q)<0.01);籽粒淀粉含量提质效应为2.39%(置信区间1.71%—3.06%,P_(Q)<0.05),仅玉米达到显著水平,效应值为3.87%(95%CI:2.86%—4.88%);籽粒蛋白质含量提质有正效应且效应值为4.99%(95%CI:3.78%—6.2%,P_(Q)>0.05),其中玉米最显著,效应值为8.90%(95%CI:4.45%—9.17%)。不同作物在施硒方式、地区和土壤硒含量等因素影响下表现各异。施硒对三种作物产量、硒含量、淀粉和蛋白质含量均有较大影响,是提升作物品质和产量的有效手段,但需依作物种类、地区和土壤条件优化施硒策略,保障人体硒营养摄入和农业优质高产。展开更多
目的:探索腰椎疾病患者血清尿酸/肌酐比值(serum uric acid/creatinine,SUA/Cr)与骨骼肌质量指数(muscle mass index,SMI)的相关性。方法:选取2023年9月至2024年9月收治的101例腰椎疾病住院患者,收集患者临床资料及实验室检查结果,使用...目的:探索腰椎疾病患者血清尿酸/肌酐比值(serum uric acid/creatinine,SUA/Cr)与骨骼肌质量指数(muscle mass index,SMI)的相关性。方法:选取2023年9月至2024年9月收治的101例腰椎疾病住院患者,收集患者临床资料及实验室检查结果,使用双能X线吸收测定法(dual-energy X-ray absorptiometry,DXA)测量骨密度、SMI以及身体质量指数(body mass index,BMI)。并根据2019年亚洲肌肉减少症工作组(Asian Working Group for Sarcopenia,AWGS)的诊断标准,分为SMI降低组(51例)和SMI正常组(50例),比较两组的临床资料。通过Spearman相关分析研究SMI与相关变量之间的相关性,通过多因素Logistics回归分析SMI的影响因素。结果:两组经单因素分析比较,在BMI、全身骨密度(total body bone mineral density,TBMD)、血红蛋白(hemoglobin,HB)、血尿酸(uric acid,UA)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、SUA/Cr方面差异均有统计学意义(P<0.05)。将两组间比较P<0.05的指标与SMI进行Spearman相关分析,结果显示SMI降低组与正常组中SMI与BMI、TBMD、HB、UA、SUA/Cr均成正相关(P<0.05),与HDL-C成负相关,两组SMI与各指标的相关性方向一致。以是否SMI降低(SMI降低=1,SMI正常=0)为因变量,以相关性有统计学意义(P<0.05)的指标为自变量进行多重Logistic回归分析。尽管两组基线特征存在差异,但相关性分析中SMI与各指标的相关性方向一致,因此在Logistic分析中做总样本量分析(样本量=101例),采用向前回归法对回归方程进行评价,得到自变量为BMI、TBMD、HDL-C、SUA/Cr的回归模型,分析显示:BMI、TBMD、HDL-C、SUA/Cr是SMI的独立影响因素。结论:低SUA/Cr是腰椎疾病患者低SMI的危险因素。对于SUA/Cr较低的腰椎疾病患者,应注意筛查肌少症。展开更多
AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).MET...AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).METHODS:A cohort participant without DR diagnosed with T1DM,underwent comprehensive ophthalmologic evaluation,optical coherence tomography angiography retinal structural and microvascular density analysis,and systemic parameter assessment.Multiple linear regression analysis was used to investigate the impact of systemic parameters on retinal alterations in distinct gender groups.RESULTS:A total of 182 individuals were included,consisting of 85 males(mean age 23.28±12.75y)and 97 females(mean age 22.98±13.68y).Males exhibited significantly greater thickness in both the internal retinal layer and the entire retina compared to females(P<0.01),whereas females had higher densities of deep retinal vessels and choroidal capillaries(P<0.05).Additionally,glycemic control was found to have a notable influence on retinal thickness in males(P<0.05),while insulin function had a more pronounced impact on retinal structure in females(P<0.01).Furthermore,a significant correlation was observed between thyroid function markers and retinal parameters in both male and female(P<0.05).CONCLUSION:Sex differences in alterations in retinal structure and microcirculation are observed in individuals with T1DM prior to the development of clinical DR,with a noted association between these changes and systemic parameters.展开更多
As cataract surgery progresses from “restoration of sight” to “refractive correction”, precise prediction of intraocular lens (IOL) power is critical for enhancing postoperative visual quality in patients. IOL pow...As cataract surgery progresses from “restoration of sight” to “refractive correction”, precise prediction of intraocular lens (IOL) power is critical for enhancing postoperative visual quality in patients. IOL power calculation methods have evolved and innovated throughout time, from early theoretical and regression formulas to nonlinear formulas for estimating effective lens position (ELP), multivariable formulas, and innovative formulas that use optical principles and AI-based online formulas. This paper thoroughly discusses the development and iteration of traditional IOL calculation formulas, the emergence of new IOL calculation formulas, and the selection of IOL calculation formulas for different patients in the era of refractive cataract surgery, serving as a reference for “personalized” IOL implantation in clinical practice.展开更多
文摘硒作为人体必需微量元素,在抗氧化、心血管保护、免疫增强及癌症预防等生理功能中具有关键作用。针对我国72%土壤缺硒的现状,通过作物施硒转化为有机硒是安全经济的补硒途径。本研究系统评估施硒对水稻、小麦、玉米的增产提质效应,为科学施硒提供理论依据。研究收集2013—2024年中国知网、维普、万方、Web of Science及PubMed数据库中134篇田间试验文献,以“硒”“小麦/玉米/水稻”“产量”为关键词,采用响应比自然对数(lnR)作为效应值进行Meta分析,借助Microsoft Office、Get Data Graph Digitizer、MetaWin 2.1等软件处理数据。施硒总体使水稻、小麦、玉米增产5.41%(95%CI:4.74%—6.08%,P_(Q)<0.01),其中小麦和水稻增产显著,分别提升8.72%(95%CI:7.69%—9.75%)和6.35%(95%CI:6.34%—7.71%),玉米增产不明显,效应值仅为0.46%(95%CI:-0.71%—1.63%)且lnR的95%置信区间下限小于0;施硒显著提升籽粒硒含量(164.09%,95%CI:156.15%—169.21%,P_(Q)<0.01),玉米提升效果最佳,效应值为172.97%(95%CI:164.55%—181.39%,P_(Q)<0.01);籽粒淀粉含量提质效应为2.39%(置信区间1.71%—3.06%,P_(Q)<0.05),仅玉米达到显著水平,效应值为3.87%(95%CI:2.86%—4.88%);籽粒蛋白质含量提质有正效应且效应值为4.99%(95%CI:3.78%—6.2%,P_(Q)>0.05),其中玉米最显著,效应值为8.90%(95%CI:4.45%—9.17%)。不同作物在施硒方式、地区和土壤硒含量等因素影响下表现各异。施硒对三种作物产量、硒含量、淀粉和蛋白质含量均有较大影响,是提升作物品质和产量的有效手段,但需依作物种类、地区和土壤条件优化施硒策略,保障人体硒营养摄入和农业优质高产。
文摘目的:探索腰椎疾病患者血清尿酸/肌酐比值(serum uric acid/creatinine,SUA/Cr)与骨骼肌质量指数(muscle mass index,SMI)的相关性。方法:选取2023年9月至2024年9月收治的101例腰椎疾病住院患者,收集患者临床资料及实验室检查结果,使用双能X线吸收测定法(dual-energy X-ray absorptiometry,DXA)测量骨密度、SMI以及身体质量指数(body mass index,BMI)。并根据2019年亚洲肌肉减少症工作组(Asian Working Group for Sarcopenia,AWGS)的诊断标准,分为SMI降低组(51例)和SMI正常组(50例),比较两组的临床资料。通过Spearman相关分析研究SMI与相关变量之间的相关性,通过多因素Logistics回归分析SMI的影响因素。结果:两组经单因素分析比较,在BMI、全身骨密度(total body bone mineral density,TBMD)、血红蛋白(hemoglobin,HB)、血尿酸(uric acid,UA)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、SUA/Cr方面差异均有统计学意义(P<0.05)。将两组间比较P<0.05的指标与SMI进行Spearman相关分析,结果显示SMI降低组与正常组中SMI与BMI、TBMD、HB、UA、SUA/Cr均成正相关(P<0.05),与HDL-C成负相关,两组SMI与各指标的相关性方向一致。以是否SMI降低(SMI降低=1,SMI正常=0)为因变量,以相关性有统计学意义(P<0.05)的指标为自变量进行多重Logistic回归分析。尽管两组基线特征存在差异,但相关性分析中SMI与各指标的相关性方向一致,因此在Logistic分析中做总样本量分析(样本量=101例),采用向前回归法对回归方程进行评价,得到自变量为BMI、TBMD、HDL-C、SUA/Cr的回归模型,分析显示:BMI、TBMD、HDL-C、SUA/Cr是SMI的独立影响因素。结论:低SUA/Cr是腰椎疾病患者低SMI的危险因素。对于SUA/Cr较低的腰椎疾病患者,应注意筛查肌少症。
基金Supported by Natural Science Foundation of Hunan Province(No.2023JJ70017No.2025JJ50627)Peak Climbing Project of Optometry Hospital Affiliated to Wenzhou Medical University。
文摘AIM:To investigate the sex-specific correlation between systemic factors and retinal neurovascular alterations in individuals with type 1 diabetes mellitus(T1DM)who do not exhibit signs of diabetic retinopathy(DR).METHODS:A cohort participant without DR diagnosed with T1DM,underwent comprehensive ophthalmologic evaluation,optical coherence tomography angiography retinal structural and microvascular density analysis,and systemic parameter assessment.Multiple linear regression analysis was used to investigate the impact of systemic parameters on retinal alterations in distinct gender groups.RESULTS:A total of 182 individuals were included,consisting of 85 males(mean age 23.28±12.75y)and 97 females(mean age 22.98±13.68y).Males exhibited significantly greater thickness in both the internal retinal layer and the entire retina compared to females(P<0.01),whereas females had higher densities of deep retinal vessels and choroidal capillaries(P<0.05).Additionally,glycemic control was found to have a notable influence on retinal thickness in males(P<0.05),while insulin function had a more pronounced impact on retinal structure in females(P<0.01).Furthermore,a significant correlation was observed between thyroid function markers and retinal parameters in both male and female(P<0.05).CONCLUSION:Sex differences in alterations in retinal structure and microcirculation are observed in individuals with T1DM prior to the development of clinical DR,with a noted association between these changes and systemic parameters.
文摘As cataract surgery progresses from “restoration of sight” to “refractive correction”, precise prediction of intraocular lens (IOL) power is critical for enhancing postoperative visual quality in patients. IOL power calculation methods have evolved and innovated throughout time, from early theoretical and regression formulas to nonlinear formulas for estimating effective lens position (ELP), multivariable formulas, and innovative formulas that use optical principles and AI-based online formulas. This paper thoroughly discusses the development and iteration of traditional IOL calculation formulas, the emergence of new IOL calculation formulas, and the selection of IOL calculation formulas for different patients in the era of refractive cataract surgery, serving as a reference for “personalized” IOL implantation in clinical practice.
