Lithium metal batteries(LMBs)are considered the ideal next-generation high-energy-density systems,capable of surpassing the performance of lithium-ion batteries(LIBs).However,LMBs suffer from issues such as irreversib...Lithium metal batteries(LMBs)are considered the ideal next-generation high-energy-density systems,capable of surpassing the performance of lithium-ion batteries(LIBs).However,LMBs suffer from issues such as irreversible Li deposition/stripping,dendrite growth and significant volume fluctuations.Here,we use doctor blade coating to precisely control the loading of the bulk hard carbon(BHC)host with closed nanopores on carbon-coated copper(CCu)foil to achieve optimal cycling stability and rate performance for Li metal and anode-free battery systems.Through ex/in-situ techniques,we demonstrate that the BHC host induces a continuous intercalation-deposition mechanism,where the pre-lithiated BHC(preliBHC)phase,formed by Li+intercalation,improves Li affinity,accelerates Li+transport,and reduces nucleation overpotential,resulting in uniform Li deposition and effectively suppressing dendrite growth.Furthermore,these characterizations reveal that irreversible Li deintercalation from graphite layers is a key factor leading to the low initial Coulombic efficiency(ICE).Consequently,when coupled with a LiFePO_(4)cathode,the BHC-based full cell retains 96.3% of its capacity after 210 cycles at 1 C,demonstrating exceptional cycling stability.Notably,at-20℃,the full cell maintains 94.2% capacity retention after 60 cycles.These findings deepen the understanding of regulating Li metal deposition mechanisms and offer valuable insights into designing Li metal hosts for improved cycle life and high-rate performance.展开更多
Sesamum indicum has various biological effects,and this study aimed to investigate its hypolipidemic effect.A hyperlipidemia rat model was established by feeding rats with high-fat diets in this study,then the hyperli...Sesamum indicum has various biological effects,and this study aimed to investigate its hypolipidemic effect.A hyperlipidemia rat model was established by feeding rats with high-fat diets in this study,then the hyperlipidemia rats were fed with different doses of black and white sesame seeds and black and white sesame kernels.The serum and liver biochemical indicators of the rats were determined,and liver pathology analysis was conducted to evaluate the hypolipidemic effect of sesame.The results showed that the blood lipid of SD(Sprague-Dawley)rats fed with high-fat diet for three weeks was higher than 200 mg/d L,indicating that the hyperlipidemia rat model was successfully established.At the same dose,the final body weights of the rats of white sesame seed and kernel groups were higher than those of the black sesame seed and kernel groups;and the weights of the black and white sesame seed groups were lower than those of the black and white sesame kernel groups.The liver indexes of the normal control group and the experimental groups were significantly lower than the model control group(P<0.05),indicating that black and white sesame seed and kernel could reduce the lipid accumulation on the liver.The malondialdehyde(MDA)values of the liver in the normal control group and the experimental groups were significantly lower than that in the model control group(P<0.05).The total antioxidant capacity(T-AOC),high density lipoprotein cholesterol(HDL-C),glutathione peroxidase(GSH-Px)and total superoxide dismutase(T-SOD)in the liver of each experimental group were significantly higher than those in the model control group(P<0.05).Based on the above results as well as pathological observation and analysis,we found that the black and white sesame seeds and kernels could improve fatty liver lesions and lipid metabolism disorder and could reduce lipid accumulation on the liver,thereby protecting the liver from damage and reducing the risk of fatty liver.Moreover,black and white sesame seeds,black and white sesame kernels can reduce the levels of total cholesterol(TC)and triglyceride(TG)in serum,and high dose of black sesame seeds(30%black sesame seeds)and low dose of black sesame kernels(10%black sesame kernels)were more beneficial for the recovery of hyperlipidemia and fatty liver.The above results indicated that black and white sesame has hypolipidemic effect.展开更多
High quality perovskite films with large columnar grains are greatly desired for efficient perovskite solar cells. Here, low volatility N-methyl-2-pyrrolidone(NMP) was added in MAI/IPA solution in a two-step spin-coat...High quality perovskite films with large columnar grains are greatly desired for efficient perovskite solar cells. Here, low volatility N-methyl-2-pyrrolidone(NMP) was added in MAI/IPA solution in a two-step spin-coating method, which promoted the conversion of lead iodide to perovskite. The perovskite films were annealed by a closed-steam annealing method to prolong the recrystallization process of perovskite films assisted by the residual NMP. It leaded to high quality CH_3NH_3PbI_3 perovskite films with large columnar grains due to its enhancement of the Oswald ripening. The large grain perovskite film leaded to efficient carrier transformation and injection, and low recombination. The photovoltaic performance of the perovskite solar cells was improved significantly.展开更多
The particle swarm optimization (PSO) algorithm is introduced to deal with some open anti-windup problems, i.e., determining the initial condition when applying the iterative algorithm to enlarge the estimate of the d...The particle swarm optimization (PSO) algorithm is introduced to deal with some open anti-windup problems, i.e., determining the initial condition when applying the iterative algorithm to enlarge the estimate of the domain of attraction, determining the design point in the delayed anti-windup scheme, and determining the design point and the weighting factors in the multi-stage anti-windup scheme. Therefore, the corresponding PSO-based algorithms are proposed. Unlike the traditional methods in which the free design parameters can only be selected by trial and error with the available computational results, the PSO-based algorithms provide a systematic way to determine these parameters. In addition, the algorithms are easy to be implemented and are very likely to find the desirable parameters that further improve the anti-windup closed-loop performances. Simulation results are presented to validate the effectiveness and advantages of the proposed method.展开更多
With the increasing number of switches in Software-Defined Network-ing(SDN),there are more and more faults rising in the data plane.However,due to the existence of link redundancy and multi-path forwarding mechanisms,t...With the increasing number of switches in Software-Defined Network-ing(SDN),there are more and more faults rising in the data plane.However,due to the existence of link redundancy and multi-path forwarding mechanisms,these problems cannot be detected in time.The current faulty path detection mechan-isms have problems such as the large scale of detection and low efficiency,which is difficult to meet the requirements of efficient faulty path detection in large-scale SDN.Concerning this issue,we propose an efficient network path fault testing model ProbD based on probability detection.This model achieves a high prob-ability of detecting arbitrary path fault in the form of small-scale random sam-pling.Under a certain path fault rate,ProbD obtains the curve of sample size and probability of detecting arbitrary path fault by randomly sampling network paths several times.After a small number of experiments,the ProbD model can cor-rectly estimate the path fault rate of the network and calculate the total number of paths that need to be detected according to the different probability of detecting arbitrary path fault and the path fault rate of the network.Thefinal experimental results show that,compared with the full path coverage test,the ProbD model based on probability detection can achieve efficient network testing with less overhead.Besides,the larger the network scale is,the more overhead will be saved.展开更多
In order to study the stress characteristics of the initial support and secondary lining of the large section tunnel and to solve the problem of secondary lining cracking during operation. Taking the large section tun...In order to study the stress characteristics of the initial support and secondary lining of the large section tunnel and to solve the problem of secondary lining cracking during operation. Taking the large section tunnel in Zihong village, Qi County as the research object, a numerical simulation method was used to establish a finite element model of the large section tunnel. So as to simulate and analyze the stress characteristics of the support structure of this tunnel. Through the simulation of the initial support and second lining of this large section tunnel in terms of displacement, stress, plastic zone damage and anchor shaft force, the results show that as the excavation progresses, the stress and displacement on the surface of the newly excavated tunnel profile is faster, especially at the side walls and arch footings, the stress and displacement values are slightly larger than other characteristic points, but the final values are stable and converge, and are basically consistent with the field monitoring results, which indicates that this support system is basically in stable state. Therefore, during the tunnel excavation and support process, special attention should be paid to the stability of the sidewalls and footings, and the results of this study will be of great practical significance for tunnel construction and maintenance.展开更多
In this article,we present recent findings from a Nature Chemical Biology paper that elucidate the mechanism of crucial biosynthetic steps involved in the synthesis of steroidal glycoalkaloids(SGAs),an important defen...In this article,we present recent findings from a Nature Chemical Biology paper that elucidate the mechanism of crucial biosynthetic steps involved in the synthesis of steroidal glycoalkaloids(SGAs),an important defense substance in a variety of Solanum plants.The enzyme GAME12,identified in Solanum lycopersicum,has evolved from the ancestral GABA enzyme through gene duplication events.Notably,GAME12 has acquired a neofunctional capability,undergoing modifications in both active site specificity and subcellular localization.This shift allows for a transition from its foundational role in core metabolism to its involvement in specialized metabolic pathways.The distinctive function of transamination enables the incorporation of nitrogen atoms into the backbones of steroidal specialized metabolites during the later stages of SGA biosynthesis,resulting in the production of nitrogen-containing antinutrients.This research underscores the significance of hijacking shunt enzymes from core metabolic pathways to facilitate the biosynthesis of nitrogen-containing steroidal glycoalkaloids,thereby enhancing the defensive mechanisms of Solanum species against pests and diseases.展开更多
Long noncoding RNAs(lncRNAs)participate in regulating many biological processes.However,their roles in influenza A virus(IAV)pathogenicity are largely unknown.Here,we analyzed the expression profiles of lncRNAs and mR...Long noncoding RNAs(lncRNAs)participate in regulating many biological processes.However,their roles in influenza A virus(IAV)pathogenicity are largely unknown.Here,we analyzed the expression profiles of lncRNAs and mRNAs in H3N2-infected cells and mock-infected cells by high-throughput sequencing.The results showed that 6129 lncRNAs and 50,031 mRNA transcripts in A549 cells displayed differential expression after H3N2 infection compared with mock infection.Among the differentially expressed lncRNAs,4963 were upregulated,and 1166 were downregulated.Functional annotation and enrichment analysis using gene ontology and Kyoto Encyclopedia of Genes and Genomes databases(KEGG)suggested that target genes of the differentially expressed lncRNAs were enriched in some biological processes,such as cellular metabolism and autophagy.The up-or downregulated lncRNAs were selected and further verified by quantitative real-time polymerase chain reaction(RT-qPCR)and reverse transcription PCR(RT-PCR).To the best of our knowledge,this is the first report of a comparative expression analysis of lncRNAs in A549 cells infected with H3N2.Our results support the need for further analyses of the functions of differentially expressed lncRNAs during H3N2 infection.展开更多
Puccinia striiformis Westend. f. sp. tritici(Pst) pathotype CYR34 is widely virulent and prevalent in China.Here, we report identification of a strpie rust resistance(Yr) gene, designated Yr041133, in winter wheat lin...Puccinia striiformis Westend. f. sp. tritici(Pst) pathotype CYR34 is widely virulent and prevalent in China.Here, we report identification of a strpie rust resistance(Yr) gene, designated Yr041133, in winter wheat line 041133. This line produced a hypersensitive reaction to CYR34 and conferred resistance to 13 other pathotypes. Resistance to CYR34 in line 041133 was controlled by a single dominant gene. Bulked segregant RNA sequencing(BSR-Seq) was performed on a pair of RNA bulks generated by pooling resistant and susceptible recombinant inbred lines. Yr041133 was mapped to a 1.7 c M genetic interval on the chromosome arm 7 BL that corresponded to a 0.8 Mb physical interval(608.9–609.7 Mb) in the Chinese Spring reference genome. Based on its unique physical location Yr041133 differred from the other Yr genes on this chromosome arm.展开更多
Multifocal multiphoton microscopy(MMM)has greatly improved the utilization of excitationlight and imaging speed due to parallel multiphoton excitation of the samples and simultaneousdetection of the signals,which allo...Multifocal multiphoton microscopy(MMM)has greatly improved the utilization of excitationlight and imaging speed due to parallel multiphoton excitation of the samples and simultaneousdetection of the signals,which allows it to perform three-dimensional fast fuorescence imaging.Stochastic scanming can provide continuous,uniform and high-speed excitation of the sample,which makes it a suitable scanning scheme for MMM.In this paper,the graphical programminglanguage,LabVIEW is used to achieve stochastic scanning of the two-dimensional galvo scanmers by using white noise signals to control the a and y mirrors independently.Moreover,thestochastic scanning process is simulated by using Monte Carlo method.Our results show that MMM can avoid oversampling or subsampling in the scanning area and meet the requirements of uniform sampling by stochastically scanning the individual units of the N×N foci array.Therefore,continuous and umiform scaning in the whole field of view is implemented.展开更多
With the expansion of network services,large-scale networks have progressively become common.The network status changes rapidly in response to customer needs and configuration changes,so network configuration changes ...With the expansion of network services,large-scale networks have progressively become common.The network status changes rapidly in response to customer needs and configuration changes,so network configuration changes are also very frequent.However,no matter what changes,the network must ensure the correct conditions,such as isolating tenants from each other or guaranteeing essential services.Once changes occur,it is necessary to verify the after-changed network.Whereas,for the verification of large-scale network configuration changes,many current verifiers show poor efficiency.In order to solve the problem ofmultiple global verifications caused by frequent updates of local configurations in large networks,we present a fast configuration updates verification tool,FastCUV,for distributed control planes.FastCUV aims to enhance the efficiency of distributed control plane verification for medium and large networks while ensuring correctness.This paper presents a method to determine the network range affected by the configuration change.We present a flow model and graph structure to facilitate the design of verification algorithms and speed up verification.Our scheme verifies the network area affected by obtaining the change of the Forwarding Information Base(FIB)before and after.FastCUV supports rich network attributes,meanwhile,has high efficiency and correctness performance.After experimental verification and result analysis,our method outperforms the state-of-the-art method to a certain extent.展开更多
Quantum transmission experiments have shown that the success-ful transmission rate of entangled quanta in optical fibers decreases expo-nentially.Although current quantum networks deploy quantum relays to establish lo...Quantum transmission experiments have shown that the success-ful transmission rate of entangled quanta in optical fibers decreases expo-nentially.Although current quantum networks deploy quantum relays to establish long-distance connections,the increase in transmission distance and entanglement switching costs still need to be considered when selecting the next hop.However,most of the existing quantum network models prefer to consider the parameters of the physical layer,which ignore the influence factors of the network layer.In this paper,we propose a meshy quantum network model based on quantum teleportation,which considers both net-work layer and physical layer parameters.The proposed model can reflect the realistic transmission characteristics and morphological characteristics of the quantum relay network.Then,we study the network throughput of different routing algorithms with the same given parameters when multiple source-destination pairs are interconnected simultaneously.To solve the chal-lenges of routing competition caused by the simultaneous transmission,we present greedy memory-occupied algorithm Q-GMOA and random memory-occupied algorithm Q-RMOA.The proposed meshy quantum network model and the memory-occupied routing algorithms can improve the utilization rate of resources and the transmission performance of the quantum network.And the evaluation results indicate that the proposed methods embrace a higher transmission rate than the previous methods with repeater occupation.展开更多
Software-defined networking(SDN)is widely used in multiple types of data center networks,and these distributed data center networks can be integrated into a multi-domain SDN by utilizing multiple controllers.However,t...Software-defined networking(SDN)is widely used in multiple types of data center networks,and these distributed data center networks can be integrated into a multi-domain SDN by utilizing multiple controllers.However,the network topology of each control domain of SDN will affect the performance of the multidomain network,so performance evaluation is required before the deployment of the multi-domain SDN.Besides,there is a high cost to build real multi-domain SDN networks with different topologies,so it is necessary to use simulation testing methods to evaluate the topological performance of the multi-domain SDN network.As there is a lack of existing methods to construct a multi-domain SDN simulation network for the tool to evaluate the topological performance automatically,this paper proposes an automated multi-domain SDN topology performance evaluation framework,which supports multiple types of SDN network topologies in cooperating to construct a multi-domain SDN network.The framework integrates existing single-domain SDN simulation tools with network performance testing tools to realize automated performance evaluation of multidomain SDN network topologies.We designed and implemented a Mininet-based simulation tool that can connect multiple controllers and run user-specified topologies in multiple SDN control domains to build and test multi-domain SDN networks faster.Then,we used the tool to perform performance tests on various data center network topologies in single-domain and multi-domain SDN simulation environments.Test results show that Space Shuffle has the most stable performance in a single-domain environment,and Fat-tree has the best performance in a multi-domain environment.Also,this tool has the characteristics of simplicity and stability,which can meet the needs of multi-domain SDN topology performance evaluation.展开更多
Discrete mathematics studies the respective structures,laws and interrelationships of different discrete quantities,which has a wide range of applications in computer science and software engineering.It has the charac...Discrete mathematics studies the respective structures,laws and interrelationships of different discrete quantities,which has a wide range of applications in computer science and software engineering.It has the characteristics of research,practice and innovation.The teaching goals of the course of discrete mathematics include not only the understanding and mastery of knowledge,but also the study of methodology.However,current teaching mechanism has limitations in outdated course contents,rare real project examples and nonscientific scoring modes.This paper attempts to think about the course construction of discrete mathematics to improve the teaching effects and cultivate students’practical ability.展开更多
This paper addresses the robust fault-tolerant control problem for a class of uncertain nonlinear switched systems with actuator saturation.Our aim is to design a switching law and a robust fault-tolerant control law ...This paper addresses the robust fault-tolerant control problem for a class of uncertain nonlinear switched systems with actuator saturation.Our aim is to design a switching law and a robust fault-tolerant control law for guaranteeing that the closed-loop system is asymptotically stabilizable,while at the same time the attraction domain estimation is as large as possible.By using the multiple Lyapunov functions method,sufficient conditions for robust fault-tolerant stabilisation are proposed for the closed-loop system.Then,when some scalar parameters are given in advance,the problem of fault-tolerant controller design and attraction domain estimation is transformed into a convex optimisation problem with linear matrix inequality(LMl)constraints.Finally the validity of the proposed design method is verified by a numerical example.展开更多
With rapid increase of distributed solar power generation and direct current(DC)based loads such as data centers,electric vehicles(EVs),and DC household appliances,the development trend of the power system is changed ...With rapid increase of distributed solar power generation and direct current(DC)based loads such as data centers,electric vehicles(EVs),and DC household appliances,the development trend of the power system is changed from conventional alternate current(AC)to DC.Traditional AC power systems can scarcely meet the development demand of new DC trends,especially since both the generation side and load side are comprised of DC-based electronic power components.With this background,low voltage direct current supply and utilization system(LVDCSUS)has attracted more and more attention for its great advantages over an AC grid to overcome challenges in operation,reliability,and energy loss in renewable energy connection,DC load power utilization and a number of other aspects.However,the definition of the LVDCSUS is still not clear even though many demonstration projects have been put into planning and operation.In order to provide a clear description of LVDCSUS,first,the characteristics of LVDCSUS are illustrated in this paper to show the advance of the LVDCSUS.Second,the potential application scenarios of LVDCSUS are presented in this paper.Third,application of LVDCSUS technologies and some demonstration projects in China are introduced.Besides the development of the LVDCSUS,key technologies,including but not limited to planning and design,voltage levels,control strategies,and key equipment of LVDCSUS,are discussed in this paper.Finally,future application areas and the research orientations of LVDCSUS are analyzed.展开更多
To meet the growing demand for wearable smart electronic devices,the development of flexible lithium-ion batteries(LIBs)is essential.Silicon is an ideal candidate for the anode material of flexible lithium-ion batteri...To meet the growing demand for wearable smart electronic devices,the development of flexible lithium-ion batteries(LIBs)is essential.Silicon is an ideal candidate for the anode material of flexible lithium-ion batteries due to its high specific capacity,low working potential,and earth abundance.The largest challenge in developing a flexible silicon anode is how to maintain structural integrity and ensure stable electrochemical reactions during external deformation.In this work,we propose a novel design for fabricating core–shell electrodes based on a copper nanowire(CuNW)array core and magnetron sputtered Si/C shell.The nanowire array structure has characteristics of bending under longitudinal stress and twisting under transverse stress,which helps to maintain the mechanical stability of the structure during electrode bending and cycling.The low-temperature annealing generates a small amount of Cu3Si alloy,which enhances the connection strength between Si and the conductive network and solves the poor conductivity problem of Si,which is known as a semiconductor material.This unique configuration design of CuNW@Si@C-400℃ leads to stable long cycle performance of 1109 mAh∙g^(-1) after 1000 cycles and excellent rate performance of 500 mAh∙g^(-1) at a current density of 10 A∙g^(-1).Furthermore,the CuNW@Si@C-400℃||LiFePO_(4)(LFP)full battery demonstrates excellent flexibility,with a capacity retention of more than 96%after 100 bends.This study provides a promising strategy for the development of flexible lithium-ion batteries.展开更多
Aligned arrays of semiconducting carbon nanotubes(s-CNTs)with high homogenous density and orientation are urgently needed for high-performance carbon-based electronics.Herein,a length-controlled approach using combine...Aligned arrays of semiconducting carbon nanotubes(s-CNTs)with high homogenous density and orientation are urgently needed for high-performance carbon-based electronics.Herein,a length-controlled approach using combined technologies was developed to regulate the s-CNT length and reduce the length distribution.The impact of different lengths and length distributions was studied during aligned self-assembly on a liquid–liquid confined interface was investigated.The results show that short s-CNTs with a narrow distribution have the best alignment uniformity over the large scale.The optimized and aligned s-CNT array can reach a density as high as 100 CNTs·μm−1 on a 4-inch wafer.The field-effect transistor(FET)performance of these optimized s-CNT arrays was 64%higher than arrays without length-control.This study clarified that rational control of s-CNTs with desired length and length distribution on the aligned self-assembly process within the liquid–liquid confined interface.The results illustrate a solid foundation for the application of emerging carbon-based electronics.展开更多
基金supported by the National Key Research and Development Program of China(2022YFE0109400)Leading Edge Technology of Jiangsu Province(BK20220009,BK20232022)+1 种基金Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Center for Microscopy and Analysis at Nanjing University of Aeronautics and Astronautics。
文摘Lithium metal batteries(LMBs)are considered the ideal next-generation high-energy-density systems,capable of surpassing the performance of lithium-ion batteries(LIBs).However,LMBs suffer from issues such as irreversible Li deposition/stripping,dendrite growth and significant volume fluctuations.Here,we use doctor blade coating to precisely control the loading of the bulk hard carbon(BHC)host with closed nanopores on carbon-coated copper(CCu)foil to achieve optimal cycling stability and rate performance for Li metal and anode-free battery systems.Through ex/in-situ techniques,we demonstrate that the BHC host induces a continuous intercalation-deposition mechanism,where the pre-lithiated BHC(preliBHC)phase,formed by Li+intercalation,improves Li affinity,accelerates Li+transport,and reduces nucleation overpotential,resulting in uniform Li deposition and effectively suppressing dendrite growth.Furthermore,these characterizations reveal that irreversible Li deintercalation from graphite layers is a key factor leading to the low initial Coulombic efficiency(ICE).Consequently,when coupled with a LiFePO_(4)cathode,the BHC-based full cell retains 96.3% of its capacity after 210 cycles at 1 C,demonstrating exceptional cycling stability.Notably,at-20℃,the full cell maintains 94.2% capacity retention after 60 cycles.These findings deepen the understanding of regulating Li metal deposition mechanisms and offer valuable insights into designing Li metal hosts for improved cycle life and high-rate performance.
基金supported by the Construction of Modern Agricultural Industrial Technology System(CARS14-1-29)。
文摘Sesamum indicum has various biological effects,and this study aimed to investigate its hypolipidemic effect.A hyperlipidemia rat model was established by feeding rats with high-fat diets in this study,then the hyperlipidemia rats were fed with different doses of black and white sesame seeds and black and white sesame kernels.The serum and liver biochemical indicators of the rats were determined,and liver pathology analysis was conducted to evaluate the hypolipidemic effect of sesame.The results showed that the blood lipid of SD(Sprague-Dawley)rats fed with high-fat diet for three weeks was higher than 200 mg/d L,indicating that the hyperlipidemia rat model was successfully established.At the same dose,the final body weights of the rats of white sesame seed and kernel groups were higher than those of the black sesame seed and kernel groups;and the weights of the black and white sesame seed groups were lower than those of the black and white sesame kernel groups.The liver indexes of the normal control group and the experimental groups were significantly lower than the model control group(P<0.05),indicating that black and white sesame seed and kernel could reduce the lipid accumulation on the liver.The malondialdehyde(MDA)values of the liver in the normal control group and the experimental groups were significantly lower than that in the model control group(P<0.05).The total antioxidant capacity(T-AOC),high density lipoprotein cholesterol(HDL-C),glutathione peroxidase(GSH-Px)and total superoxide dismutase(T-SOD)in the liver of each experimental group were significantly higher than those in the model control group(P<0.05).Based on the above results as well as pathological observation and analysis,we found that the black and white sesame seeds and kernels could improve fatty liver lesions and lipid metabolism disorder and could reduce lipid accumulation on the liver,thereby protecting the liver from damage and reducing the risk of fatty liver.Moreover,black and white sesame seeds,black and white sesame kernels can reduce the levels of total cholesterol(TC)and triglyceride(TG)in serum,and high dose of black sesame seeds(30%black sesame seeds)and low dose of black sesame kernels(10%black sesame kernels)were more beneficial for the recovery of hyperlipidemia and fatty liver.The above results indicated that black and white sesame has hypolipidemic effect.
基金financially supported by the National Natural Science Foundation of China(Grant No.21463002)Startup Funding of Distinguished Professorship of "1000 Talents Program"(31370086963030)+4 种基金Shenzhen Jiawei Photovoltaic Lighting Co.,Ltd.Tsinghua University Initiative Scientific Research Program(20161080165)Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2016D01C008)Opening Project of State Key laboratory of Crystal Material(No.KF1610)Scientific Research Program of the Higher Education Institution of Xinjiang(XJEDU2017M038)
文摘High quality perovskite films with large columnar grains are greatly desired for efficient perovskite solar cells. Here, low volatility N-methyl-2-pyrrolidone(NMP) was added in MAI/IPA solution in a two-step spin-coating method, which promoted the conversion of lead iodide to perovskite. The perovskite films were annealed by a closed-steam annealing method to prolong the recrystallization process of perovskite films assisted by the residual NMP. It leaded to high quality CH_3NH_3PbI_3 perovskite films with large columnar grains due to its enhancement of the Oswald ripening. The large grain perovskite film leaded to efficient carrier transformation and injection, and low recombination. The photovoltaic performance of the perovskite solar cells was improved significantly.
文摘The particle swarm optimization (PSO) algorithm is introduced to deal with some open anti-windup problems, i.e., determining the initial condition when applying the iterative algorithm to enlarge the estimate of the domain of attraction, determining the design point in the delayed anti-windup scheme, and determining the design point and the weighting factors in the multi-stage anti-windup scheme. Therefore, the corresponding PSO-based algorithms are proposed. Unlike the traditional methods in which the free design parameters can only be selected by trial and error with the available computational results, the PSO-based algorithms provide a systematic way to determine these parameters. In addition, the algorithms are easy to be implemented and are very likely to find the desirable parameters that further improve the anti-windup closed-loop performances. Simulation results are presented to validate the effectiveness and advantages of the proposed method.
基金supported by the Fundamental Research Funds for the Central Universities(2021RC239)the Postdoctoral Science Foundation of China(2021 M690338)+3 种基金the Hainan Provincial Natural Science Foundation of China(620RC562,2019RC096,620RC560)the Scientific Research Setup Fund of Hainan University(KYQD(ZR)1877)the Program of Hainan Association for Science and Technology Plans to Youth R&D Innovation(QCXM201910)the National Natural Science Foundation of China(61802092,62162021).
文摘With the increasing number of switches in Software-Defined Network-ing(SDN),there are more and more faults rising in the data plane.However,due to the existence of link redundancy and multi-path forwarding mechanisms,these problems cannot be detected in time.The current faulty path detection mechan-isms have problems such as the large scale of detection and low efficiency,which is difficult to meet the requirements of efficient faulty path detection in large-scale SDN.Concerning this issue,we propose an efficient network path fault testing model ProbD based on probability detection.This model achieves a high prob-ability of detecting arbitrary path fault in the form of small-scale random sam-pling.Under a certain path fault rate,ProbD obtains the curve of sample size and probability of detecting arbitrary path fault by randomly sampling network paths several times.After a small number of experiments,the ProbD model can cor-rectly estimate the path fault rate of the network and calculate the total number of paths that need to be detected according to the different probability of detecting arbitrary path fault and the path fault rate of the network.Thefinal experimental results show that,compared with the full path coverage test,the ProbD model based on probability detection can achieve efficient network testing with less overhead.Besides,the larger the network scale is,the more overhead will be saved.
文摘In order to study the stress characteristics of the initial support and secondary lining of the large section tunnel and to solve the problem of secondary lining cracking during operation. Taking the large section tunnel in Zihong village, Qi County as the research object, a numerical simulation method was used to establish a finite element model of the large section tunnel. So as to simulate and analyze the stress characteristics of the support structure of this tunnel. Through the simulation of the initial support and second lining of this large section tunnel in terms of displacement, stress, plastic zone damage and anchor shaft force, the results show that as the excavation progresses, the stress and displacement on the surface of the newly excavated tunnel profile is faster, especially at the side walls and arch footings, the stress and displacement values are slightly larger than other characteristic points, but the final values are stable and converge, and are basically consistent with the field monitoring results, which indicates that this support system is basically in stable state. Therefore, during the tunnel excavation and support process, special attention should be paid to the stability of the sidewalls and footings, and the results of this study will be of great practical significance for tunnel construction and maintenance.
基金support from the National Key Research and Development Program of China(2021YFD1700100)Excellent Youth Program of Anhui Province(2022AH030095).
文摘In this article,we present recent findings from a Nature Chemical Biology paper that elucidate the mechanism of crucial biosynthetic steps involved in the synthesis of steroidal glycoalkaloids(SGAs),an important defense substance in a variety of Solanum plants.The enzyme GAME12,identified in Solanum lycopersicum,has evolved from the ancestral GABA enzyme through gene duplication events.Notably,GAME12 has acquired a neofunctional capability,undergoing modifications in both active site specificity and subcellular localization.This shift allows for a transition from its foundational role in core metabolism to its involvement in specialized metabolic pathways.The distinctive function of transamination enables the incorporation of nitrogen atoms into the backbones of steroidal specialized metabolites during the later stages of SGA biosynthesis,resulting in the production of nitrogen-containing antinutrients.This research underscores the significance of hijacking shunt enzymes from core metabolic pathways to facilitate the biosynthesis of nitrogen-containing steroidal glycoalkaloids,thereby enhancing the defensive mechanisms of Solanum species against pests and diseases.
基金This study is supported by grants from the National Key technology R&D Program of China(Grant No.2015BAD12B01)the China Agriculture Research System(Grant No.CARS-40-K13)the National Science Foundation of China(Grant No.31502084).
文摘Long noncoding RNAs(lncRNAs)participate in regulating many biological processes.However,their roles in influenza A virus(IAV)pathogenicity are largely unknown.Here,we analyzed the expression profiles of lncRNAs and mRNAs in H3N2-infected cells and mock-infected cells by high-throughput sequencing.The results showed that 6129 lncRNAs and 50,031 mRNA transcripts in A549 cells displayed differential expression after H3N2 infection compared with mock infection.Among the differentially expressed lncRNAs,4963 were upregulated,and 1166 were downregulated.Functional annotation and enrichment analysis using gene ontology and Kyoto Encyclopedia of Genes and Genomes databases(KEGG)suggested that target genes of the differentially expressed lncRNAs were enriched in some biological processes,such as cellular metabolism and autophagy.The up-or downregulated lncRNAs were selected and further verified by quantitative real-time polymerase chain reaction(RT-qPCR)and reverse transcription PCR(RT-PCR).To the best of our knowledge,this is the first report of a comparative expression analysis of lncRNAs in A549 cells infected with H3N2.Our results support the need for further analyses of the functions of differentially expressed lncRNAs during H3N2 infection.
基金Financial support of this research by the National Key Research and Development Program of China(2017YFD0101000)the Agricultural Science and Technology Innovation Program of CAAS(CAAS-ZDRW202002)。
文摘Puccinia striiformis Westend. f. sp. tritici(Pst) pathotype CYR34 is widely virulent and prevalent in China.Here, we report identification of a strpie rust resistance(Yr) gene, designated Yr041133, in winter wheat line 041133. This line produced a hypersensitive reaction to CYR34 and conferred resistance to 13 other pathotypes. Resistance to CYR34 in line 041133 was controlled by a single dominant gene. Bulked segregant RNA sequencing(BSR-Seq) was performed on a pair of RNA bulks generated by pooling resistant and susceptible recombinant inbred lines. Yr041133 was mapped to a 1.7 c M genetic interval on the chromosome arm 7 BL that corresponded to a 0.8 Mb physical interval(608.9–609.7 Mb) in the Chinese Spring reference genome. Based on its unique physical location Yr041133 differred from the other Yr genes on this chromosome arm.
基金partially supported,by,the National Natural Science Foundation of China(11204226)the Fundamental Research Fundsfor,the Central Universities(K5051005006,K5051305002).
文摘Multifocal multiphoton microscopy(MMM)has greatly improved the utilization of excitationlight and imaging speed due to parallel multiphoton excitation of the samples and simultaneousdetection of the signals,which allows it to perform three-dimensional fast fuorescence imaging.Stochastic scanming can provide continuous,uniform and high-speed excitation of the sample,which makes it a suitable scanning scheme for MMM.In this paper,the graphical programminglanguage,LabVIEW is used to achieve stochastic scanning of the two-dimensional galvo scanmers by using white noise signals to control the a and y mirrors independently.Moreover,thestochastic scanning process is simulated by using Monte Carlo method.Our results show that MMM can avoid oversampling or subsampling in the scanning area and meet the requirements of uniform sampling by stochastically scanning the individual units of the N×N foci array.Therefore,continuous and umiform scaning in the whole field of view is implemented.
基金supported by the Fundamental Research Funds for the Central Universities(2021RC239)the Postdoctoral Science Foundation of China(2021 M690338)+3 种基金theHainan Provincial Natural Science Foundation of China(620RC562,2019RC096,620RC560)the Scientific Research Setup Fund of Hainan University(KYQD(ZR)1877)the Program of Hainan Association for Science and Technology Plans to Youth R&D Innovation(QCXM201910)the National Natural Science Foundation of China(61802092,62162021).
文摘With the expansion of network services,large-scale networks have progressively become common.The network status changes rapidly in response to customer needs and configuration changes,so network configuration changes are also very frequent.However,no matter what changes,the network must ensure the correct conditions,such as isolating tenants from each other or guaranteeing essential services.Once changes occur,it is necessary to verify the after-changed network.Whereas,for the verification of large-scale network configuration changes,many current verifiers show poor efficiency.In order to solve the problem ofmultiple global verifications caused by frequent updates of local configurations in large networks,we present a fast configuration updates verification tool,FastCUV,for distributed control planes.FastCUV aims to enhance the efficiency of distributed control plane verification for medium and large networks while ensuring correctness.This paper presents a method to determine the network range affected by the configuration change.We present a flow model and graph structure to facilitate the design of verification algorithms and speed up verification.Our scheme verifies the network area affected by obtaining the change of the Forwarding Information Base(FIB)before and after.FastCUV supports rich network attributes,meanwhile,has high efficiency and correctness performance.After experimental verification and result analysis,our method outperforms the state-of-the-art method to a certain extent.
基金supported by the Fundamental Research Funds for the Central Universities(2021RC239)the Postdoctoral Science Foundation of China(2021 M690338)+3 种基金the Hainan Provincial Natural Science Foundation of China(620RC562,2019RC096,620RC560)the Scientific Research Setup Fund of Hainan University(KYQD(ZR)1877)the Program of Hainan Association for Science and Technology Plans to Youth R&D Innovation(QCXM201910)the National Natural Science Foundation of China(61802092,62162021).
文摘Quantum transmission experiments have shown that the success-ful transmission rate of entangled quanta in optical fibers decreases expo-nentially.Although current quantum networks deploy quantum relays to establish long-distance connections,the increase in transmission distance and entanglement switching costs still need to be considered when selecting the next hop.However,most of the existing quantum network models prefer to consider the parameters of the physical layer,which ignore the influence factors of the network layer.In this paper,we propose a meshy quantum network model based on quantum teleportation,which considers both net-work layer and physical layer parameters.The proposed model can reflect the realistic transmission characteristics and morphological characteristics of the quantum relay network.Then,we study the network throughput of different routing algorithms with the same given parameters when multiple source-destination pairs are interconnected simultaneously.To solve the chal-lenges of routing competition caused by the simultaneous transmission,we present greedy memory-occupied algorithm Q-GMOA and random memory-occupied algorithm Q-RMOA.The proposed meshy quantum network model and the memory-occupied routing algorithms can improve the utilization rate of resources and the transmission performance of the quantum network.And the evaluation results indicate that the proposed methods embrace a higher transmission rate than the previous methods with repeater occupation.
基金This work was supported by the Fundamental Research Funds for the Central Universities(2021RC239)the Postdoctoral Science Foundation of China(2021 M690338)+3 种基金the Hainan Provincial Natural Science Foundation of China(620RC562,2019RC096,620RC560)the Scientific Research Setup Fund of Hainan University(KYQD(ZR)1877)the Program of Hainan Association for Science and Technology Plans to Youth R&D Innovation(QCXM201910)the National Natural Science Foundation of China(61802092,62162021).
文摘Software-defined networking(SDN)is widely used in multiple types of data center networks,and these distributed data center networks can be integrated into a multi-domain SDN by utilizing multiple controllers.However,the network topology of each control domain of SDN will affect the performance of the multidomain network,so performance evaluation is required before the deployment of the multi-domain SDN.Besides,there is a high cost to build real multi-domain SDN networks with different topologies,so it is necessary to use simulation testing methods to evaluate the topological performance of the multi-domain SDN network.As there is a lack of existing methods to construct a multi-domain SDN simulation network for the tool to evaluate the topological performance automatically,this paper proposes an automated multi-domain SDN topology performance evaluation framework,which supports multiple types of SDN network topologies in cooperating to construct a multi-domain SDN network.The framework integrates existing single-domain SDN simulation tools with network performance testing tools to realize automated performance evaluation of multidomain SDN network topologies.We designed and implemented a Mininet-based simulation tool that can connect multiple controllers and run user-specified topologies in multiple SDN control domains to build and test multi-domain SDN networks faster.Then,we used the tool to perform performance tests on various data center network topologies in single-domain and multi-domain SDN simulation environments.Test results show that Space Shuffle has the most stable performance in a single-domain environment,and Fat-tree has the best performance in a multi-domain environment.Also,this tool has the characteristics of simplicity and stability,which can meet the needs of multi-domain SDN topology performance evaluation.
基金supported by the Hainan Provincial Natural Science Foundation of China(Grant No.620RC562)the Program of Hainan Association for Science and Technology Plans to Youth R&D Innovation(Grant No.QCXM201910)the National Natural Science Foundation of China(Grant No.61802092).
文摘Discrete mathematics studies the respective structures,laws and interrelationships of different discrete quantities,which has a wide range of applications in computer science and software engineering.It has the characteristics of research,practice and innovation.The teaching goals of the course of discrete mathematics include not only the understanding and mastery of knowledge,but also the study of methodology.However,current teaching mechanism has limitations in outdated course contents,rare real project examples and nonscientific scoring modes.This paper attempts to think about the course construction of discrete mathematics to improve the teaching effects and cultivate students’practical ability.
基金supported by the Scientific Research Fund of Education Department of Liaoning Province of China[grant number LJKMZ20220731]supported by the Natural Science Foundation of Liaoning Province of China[grant number 2020-MS-283].
文摘This paper addresses the robust fault-tolerant control problem for a class of uncertain nonlinear switched systems with actuator saturation.Our aim is to design a switching law and a robust fault-tolerant control law for guaranteeing that the closed-loop system is asymptotically stabilizable,while at the same time the attraction domain estimation is as large as possible.By using the multiple Lyapunov functions method,sufficient conditions for robust fault-tolerant stabilisation are proposed for the closed-loop system.Then,when some scalar parameters are given in advance,the problem of fault-tolerant controller design and attraction domain estimation is transformed into a convex optimisation problem with linear matrix inequality(LMl)constraints.Finally the validity of the proposed design method is verified by a numerical example.
文摘With rapid increase of distributed solar power generation and direct current(DC)based loads such as data centers,electric vehicles(EVs),and DC household appliances,the development trend of the power system is changed from conventional alternate current(AC)to DC.Traditional AC power systems can scarcely meet the development demand of new DC trends,especially since both the generation side and load side are comprised of DC-based electronic power components.With this background,low voltage direct current supply and utilization system(LVDCSUS)has attracted more and more attention for its great advantages over an AC grid to overcome challenges in operation,reliability,and energy loss in renewable energy connection,DC load power utilization and a number of other aspects.However,the definition of the LVDCSUS is still not clear even though many demonstration projects have been put into planning and operation.In order to provide a clear description of LVDCSUS,first,the characteristics of LVDCSUS are illustrated in this paper to show the advance of the LVDCSUS.Second,the potential application scenarios of LVDCSUS are presented in this paper.Third,application of LVDCSUS technologies and some demonstration projects in China are introduced.Besides the development of the LVDCSUS,key technologies,including but not limited to planning and design,voltage levels,control strategies,and key equipment of LVDCSUS,are discussed in this paper.Finally,future application areas and the research orientations of LVDCSUS are analyzed.
基金Financial supports from the National Natural Science Foundation of China(No.22209075)the Natural Science Foundation of Chongqing(No.2022NSCQ-MSX4268)+1 种基金the Postdoctoral Innovation Talents Support Plan of Chongqing(No.CQBX2021012)the Scientific Research Project of Fujian Provincial Department of Education(No.JAT220530)are acknowledged.
文摘To meet the growing demand for wearable smart electronic devices,the development of flexible lithium-ion batteries(LIBs)is essential.Silicon is an ideal candidate for the anode material of flexible lithium-ion batteries due to its high specific capacity,low working potential,and earth abundance.The largest challenge in developing a flexible silicon anode is how to maintain structural integrity and ensure stable electrochemical reactions during external deformation.In this work,we propose a novel design for fabricating core–shell electrodes based on a copper nanowire(CuNW)array core and magnetron sputtered Si/C shell.The nanowire array structure has characteristics of bending under longitudinal stress and twisting under transverse stress,which helps to maintain the mechanical stability of the structure during electrode bending and cycling.The low-temperature annealing generates a small amount of Cu3Si alloy,which enhances the connection strength between Si and the conductive network and solves the poor conductivity problem of Si,which is known as a semiconductor material.This unique configuration design of CuNW@Si@C-400℃ leads to stable long cycle performance of 1109 mAh∙g^(-1) after 1000 cycles and excellent rate performance of 500 mAh∙g^(-1) at a current density of 10 A∙g^(-1).Furthermore,the CuNW@Si@C-400℃||LiFePO_(4)(LFP)full battery demonstrates excellent flexibility,with a capacity retention of more than 96%after 100 bends.This study provides a promising strategy for the development of flexible lithium-ion batteries.
基金This work was supported by National Key Research and Development Program of China(No.2020YFA0714700)National Natural Science Foundation of China(Nos.22075312 and 21773292)Key-Area Research and Development Program of Guangdong Province(No.2019B010934001).
文摘Aligned arrays of semiconducting carbon nanotubes(s-CNTs)with high homogenous density and orientation are urgently needed for high-performance carbon-based electronics.Herein,a length-controlled approach using combined technologies was developed to regulate the s-CNT length and reduce the length distribution.The impact of different lengths and length distributions was studied during aligned self-assembly on a liquid–liquid confined interface was investigated.The results show that short s-CNTs with a narrow distribution have the best alignment uniformity over the large scale.The optimized and aligned s-CNT array can reach a density as high as 100 CNTs·μm−1 on a 4-inch wafer.The field-effect transistor(FET)performance of these optimized s-CNT arrays was 64%higher than arrays without length-control.This study clarified that rational control of s-CNTs with desired length and length distribution on the aligned self-assembly process within the liquid–liquid confined interface.The results illustrate a solid foundation for the application of emerging carbon-based electronics.
