Rural tourism industry is a new typical tourism industry in China to promote the strategic integration and linkage development of secondary and tertiary industries,and has developed into a new path to promote the stra...Rural tourism industry is a new typical tourism industry in China to promote the strategic integration and linkage development of secondary and tertiary industries,and has developed into a new path to promote the strategic integration and development of rural major projects and revitalize industries[1].At present,China's rural cultural tourism is developing rapidly,but there are also some problems,such as single construction mode,accurate product positioning,lack of cultural connotation,etc.,facing the development dilemma of high quality[2].Under the background of rural revitalization strategy,the overall development of eco-tourism is an important direction of rural tourism development[3].Meiling town is located in the present Xinjian District of Nanchang City(the former Wanli District).As the central garden of Nanchang City,Meiling town has a good tourism foundation and rich eco-tourism resources,with good prospects of eco-tourism development.Taking Xujia Village in Meiling town as an example,this article analyzes the favorable and unfavorable factors of rural tourism development,and puts forward a new rural tourism development road with rural tourism as the center,ecological civilization construction as the core and rural reconstruction as the guiding concept.展开更多
In May 2019,the construction of the land and space planning system was officially launched.The Ministry of Natural Resources of the State Council issued the Notice on Comprehensively Implementing Land and Space Planni...In May 2019,the construction of the land and space planning system was officially launched.The Ministry of Natural Resources of the State Council issued the Notice on Comprehensively Implementing Land and Space Planning,which clearly requires all regions to comprehensively launch the land and space planning and puts forward specific work requirements[1].Later,in order to guide the preparation and implementation of land and space planning,various technical standards were successively issued.The dual-assessment technical guidelines,land use classification standards,and the compilation guidelines for provincial,city and county planning were gradually submitted for review and trial implementation.In this context,there have been more and more planning theories and practical studies based on the background of land and space planning.For tourist service towns,how to protect the style and features of the towns under the land and space planning system and preserve the local characteristics is a problem that needs to be solved urgently[2].展开更多
This study aimed to develop and validate a novel pathological scoring system,the MSE score(microvascular invasion,satellite foci,Edmondson-Steiner grade),for predicting postoperative recurrence in hepatocellular carci...This study aimed to develop and validate a novel pathological scoring system,the MSE score(microvascular invasion,satellite foci,Edmondson-Steiner grade),for predicting postoperative recurrence in hepatocellular carcinoma(HCC)patients at BCLC stage 0-A following liver resection.The MSE score was compared to the established microvascular invasion/satellitosis(m VI/S)scoring system,which combines microvascular invasion and satellite nodules,both of which are significant predictors of aggressive recurrence and mortality.A total of 3,338 patients from 28 centers,who underwent curative liver resection between January 2017 and January 2020,were included.These patients were divided into a training cohort(n=2,337)and a validation cohort(n=1,001).Univariate and multivariate Cox regression models,along with Kaplan-Meier survival analysis,receiver operating characteristic(ROC)curves,and random forest modeling,were used to assess recurrence factors and compare predictive performance.The results showed that the MSE score had superior discriminatory power compared to m VI/S in predicting recurrence and overall survival.Kaplan-Meier analysis indicated a significantly better separation of low-and high-risk groups with the MSE score(P<0.001),while ROC analysis revealed higher AUC values for the MSE score at 1,3,and 5 years.Multivariate Cox analysis demonstrated higher predictive power for the MSE score(HR=2.900(1.808-4.652))compared to m VI/S(HR=2.134(1.567-3.043)).Additionally,logistic regression confirmed that the MSE score had stronger predictive power for aggressive recurrence(OR=2.992(1.816-4.862)vs.m VI/S OR=1.847(1.105-3.470)).SHAP analysis highlighted that the MSE score was more significant than m VI/S.The MSE score also outperformed traditional BCLC staging,TNM staging,and preoperative serum AFP levels in predicting recurrence.In conclusion,the MSE score provides reliable predictions for postoperative aggressive recurrence and survival in BCLC stage 0-A HCC,offering superior risk stratification compared to m VI/S and promising utility in guiding postoperative management.展开更多
文摘Rural tourism industry is a new typical tourism industry in China to promote the strategic integration and linkage development of secondary and tertiary industries,and has developed into a new path to promote the strategic integration and development of rural major projects and revitalize industries[1].At present,China's rural cultural tourism is developing rapidly,but there are also some problems,such as single construction mode,accurate product positioning,lack of cultural connotation,etc.,facing the development dilemma of high quality[2].Under the background of rural revitalization strategy,the overall development of eco-tourism is an important direction of rural tourism development[3].Meiling town is located in the present Xinjian District of Nanchang City(the former Wanli District).As the central garden of Nanchang City,Meiling town has a good tourism foundation and rich eco-tourism resources,with good prospects of eco-tourism development.Taking Xujia Village in Meiling town as an example,this article analyzes the favorable and unfavorable factors of rural tourism development,and puts forward a new rural tourism development road with rural tourism as the center,ecological civilization construction as the core and rural reconstruction as the guiding concept.
文摘In May 2019,the construction of the land and space planning system was officially launched.The Ministry of Natural Resources of the State Council issued the Notice on Comprehensively Implementing Land and Space Planning,which clearly requires all regions to comprehensively launch the land and space planning and puts forward specific work requirements[1].Later,in order to guide the preparation and implementation of land and space planning,various technical standards were successively issued.The dual-assessment technical guidelines,land use classification standards,and the compilation guidelines for provincial,city and county planning were gradually submitted for review and trial implementation.In this context,there have been more and more planning theories and practical studies based on the background of land and space planning.For tourist service towns,how to protect the style and features of the towns under the land and space planning system and preserve the local characteristics is a problem that needs to be solved urgently[2].
基金supported by the National Key Research and Development Program of China(2023ZD0502001)the National Natural Science Foundation of China(82473040)+1 种基金Hubei Provincial Cutting-Edge Technology Research Project(2023BAA016-3)Tongji Hospital High-Quality Clinical Research Fund(2024TJCR014)。
文摘This study aimed to develop and validate a novel pathological scoring system,the MSE score(microvascular invasion,satellite foci,Edmondson-Steiner grade),for predicting postoperative recurrence in hepatocellular carcinoma(HCC)patients at BCLC stage 0-A following liver resection.The MSE score was compared to the established microvascular invasion/satellitosis(m VI/S)scoring system,which combines microvascular invasion and satellite nodules,both of which are significant predictors of aggressive recurrence and mortality.A total of 3,338 patients from 28 centers,who underwent curative liver resection between January 2017 and January 2020,were included.These patients were divided into a training cohort(n=2,337)and a validation cohort(n=1,001).Univariate and multivariate Cox regression models,along with Kaplan-Meier survival analysis,receiver operating characteristic(ROC)curves,and random forest modeling,were used to assess recurrence factors and compare predictive performance.The results showed that the MSE score had superior discriminatory power compared to m VI/S in predicting recurrence and overall survival.Kaplan-Meier analysis indicated a significantly better separation of low-and high-risk groups with the MSE score(P<0.001),while ROC analysis revealed higher AUC values for the MSE score at 1,3,and 5 years.Multivariate Cox analysis demonstrated higher predictive power for the MSE score(HR=2.900(1.808-4.652))compared to m VI/S(HR=2.134(1.567-3.043)).Additionally,logistic regression confirmed that the MSE score had stronger predictive power for aggressive recurrence(OR=2.992(1.816-4.862)vs.m VI/S OR=1.847(1.105-3.470)).SHAP analysis highlighted that the MSE score was more significant than m VI/S.The MSE score also outperformed traditional BCLC staging,TNM staging,and preoperative serum AFP levels in predicting recurrence.In conclusion,the MSE score provides reliable predictions for postoperative aggressive recurrence and survival in BCLC stage 0-A HCC,offering superior risk stratification compared to m VI/S and promising utility in guiding postoperative management.
