Non-antibiotic fungicides are urgently needed due to the potential threat of drug-resistant bacteria to human health.In this research,a novel antibacterial nanoplatform based on CeO_(2)@C-N has been developed to achie...Non-antibiotic fungicides are urgently needed due to the potential threat of drug-resistant bacteria to human health.In this research,a novel antibacterial nanoplatform based on CeO_(2)@C-N has been developed to achieve rapid near-infrared(NIR)laser-induced sterilization.The prepared CeO_(2)@C-N hybrid material exhibited a nanowire-like structure,with dispersed CeO_(2)nanoparticles averaging 5 nm in size within the heterogeneous configuration.X-ray photoelectron spectroscopy(XPS)and Raman spectra revealed that the heterogenous structures have a significant amount of oxygen vacancies and defects.Notably,CeO_(2)@C-N has a narrower band gap than CeO_(2),which allows for broader absorbance extending to the NIR region.With these unique physiochemical properties,CeO_(2)@C-N could inactivate E.coli and MRSA at a low concentration(20 mg/L)under 808 nm NIR laser(1 W/cm^(2))irradiation.The excellent bactericidal activity of CeO_(2)@C-N is attributed to the combination of photodynamic and photo thermal processes,based on its excellent photo-thermal conversion property,detection of reactive oxygen species(ROS)(^(1)O_(2)and·OH)under light irradiation,and scavenger quenching experiment results.This study offers a feasible and efficient way to fabricate a highly effective antibacterial candidate.展开更多
基金supported by the National Natural Science Foundation of China(21906033)the introduced innovative R&D team project under the“The Pearl River Talent Recruitment Program”of Guangdong Province(2019ZT08L387)+2 种基金the Natural Science Foundation of Guangzhou City(202102020570,202201020392)the Depar tment of Science and Technology of Hubei Province(2019CFB365)the Department of Education of Hubei Province(Q20192805)
文摘Non-antibiotic fungicides are urgently needed due to the potential threat of drug-resistant bacteria to human health.In this research,a novel antibacterial nanoplatform based on CeO_(2)@C-N has been developed to achieve rapid near-infrared(NIR)laser-induced sterilization.The prepared CeO_(2)@C-N hybrid material exhibited a nanowire-like structure,with dispersed CeO_(2)nanoparticles averaging 5 nm in size within the heterogeneous configuration.X-ray photoelectron spectroscopy(XPS)and Raman spectra revealed that the heterogenous structures have a significant amount of oxygen vacancies and defects.Notably,CeO_(2)@C-N has a narrower band gap than CeO_(2),which allows for broader absorbance extending to the NIR region.With these unique physiochemical properties,CeO_(2)@C-N could inactivate E.coli and MRSA at a low concentration(20 mg/L)under 808 nm NIR laser(1 W/cm^(2))irradiation.The excellent bactericidal activity of CeO_(2)@C-N is attributed to the combination of photodynamic and photo thermal processes,based on its excellent photo-thermal conversion property,detection of reactive oxygen species(ROS)(^(1)O_(2)and·OH)under light irradiation,and scavenger quenching experiment results.This study offers a feasible and efficient way to fabricate a highly effective antibacterial candidate.
