低压配电台区负荷投切不规范或表计错误建档等工程问题都将导致云端业务系统出现拓扑数据异常(topology data exception,TDE)。这类情况多发生在电压曲线高度近似的同电源点网络,通过现有方法难以监测。为此提出了一种基于线损贡献度的...低压配电台区负荷投切不规范或表计错误建档等工程问题都将导致云端业务系统出现拓扑数据异常(topology data exception,TDE)。这类情况多发生在电压曲线高度近似的同电源点网络,通过现有方法难以监测。为此提出了一种基于线损贡献度的同源低压配电台区拓扑数据治理方法。首先根据线损方程得到台区下终端用户的回归系数和线损贡献度指标,并将指标突破阈值的TDE逐轮撤出台区。接着针对多个异常拓扑功率堆叠使线损波动特征大量丢失的问题,提出回归系数强制趋向策略,通过构建贝叶斯回归模型并融入具有双峰特性的边界趋向鼓励机制进一步检出潜在的TDE。最后提出基于电压相关性和线损平衡的阶梯式归真模型,先通过相关性分析逐级定位TDE隶属的10kV首端大馈线和0.4kV低压台区集,再利用线损贡献度规则溯源其准确的户变关系,实现拓扑数据闭环治理。所提方法已部署至华东某电力公司数据中台,并用八百余个实际台区数据验证校核,识别准确率为97.05%,具备较好的鲁棒性与泛用性。展开更多
回顾性分析了美国食品药品监督管理局制造商和用户设施设备体验(Manufacturer and User Facility Device Experience,MAUDE)数据库2021年1月至2024年6月的弹簧圈不良事件,结合山东省内医院调研和专家论证情况指出了弹簧圈在临床使用过...回顾性分析了美国食品药品监督管理局制造商和用户设施设备体验(Manufacturer and User Facility Device Experience,MAUDE)数据库2021年1月至2024年6月的弹簧圈不良事件,结合山东省内医院调研和专家论证情况指出了弹簧圈在临床使用过程中存在的风险点并进行了原因分析,提出了落实注册人的主体责任、提高使用单位的专业技能、强化监管部门的监管力度等改进措施,为弹簧圈的安全使用提供了参考。展开更多
Soil salinization is a major abiotic stress that hampers plant development and significantly reduces agricultural productivity,posing a serious challenge to global food security.Akebia trifoliata(Thunb.)Koidz,a specie...Soil salinization is a major abiotic stress that hampers plant development and significantly reduces agricultural productivity,posing a serious challenge to global food security.Akebia trifoliata(Thunb.)Koidz,a species within the genus Akebia Decne.,is valued for its use in food,traditionalmedicine,oil production,and as an ornamental plant.Curcumin,widely recognized for its pharmacological properties including anti-cancer,anti-neuroinflammatory,and anti-fibrotic effects,has recently drawn interest for its potential roles in plant stress responses.However,its impact on plant tolerance to saline-alkali stress remains poorly understood.In this study,the effects of curcumin on saline-alkali resistance in A.trifoliata were examined by subjecting plants to a saline-alkali solution containing 150 mmol/L sodium ions(a mixture of Na_(2)SO_(4),Na_(2)CO_(3),and NaHCO_(3)).Curcumin treatment under these stress conditions leads to anatomical improvements in leaf structure.Furthermore,A.trifoliatamaintained a favorable Na^(+)/K^(+)ratio through increased potassium uptake and reduced sodium accumulation.Biochemical analysis revealed elevated levels of proline,soluble sugars,and soluble proteins,along with improved activities of antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),and peroxidase(POD).Similarly,the concentrations of hydrogen peroxide(H_(2)O_(2))and malondialdehyde(MDA)were significantly reduced.Transcriptome analysis under saline-alkali stress conditions showed that curcumin influenced seven keymetabolic pathways annotated in the Kyoto Encyclopedia of Genes and Genomes(KEGG)database,with differentially expressed unigenes primarily enriched in transcription factor families such as MYB,AP2/ERF,NAC,bHLH,and C2C2.Moreover,eight differentially expressed genes(DEGs)associated with plant hormone signal transduction were linked to the auxin and brassinosteroid pathways,critical for cell elongation and plant growth.These findings indicate that curcumin increases saline-alkali stress tolerance in A.trifoliata by modulating physiological,biochemical,and transcriptional responses,ultimately supporting improved growth under adverse conditions.展开更多
文摘低压配电台区负荷投切不规范或表计错误建档等工程问题都将导致云端业务系统出现拓扑数据异常(topology data exception,TDE)。这类情况多发生在电压曲线高度近似的同电源点网络,通过现有方法难以监测。为此提出了一种基于线损贡献度的同源低压配电台区拓扑数据治理方法。首先根据线损方程得到台区下终端用户的回归系数和线损贡献度指标,并将指标突破阈值的TDE逐轮撤出台区。接着针对多个异常拓扑功率堆叠使线损波动特征大量丢失的问题,提出回归系数强制趋向策略,通过构建贝叶斯回归模型并融入具有双峰特性的边界趋向鼓励机制进一步检出潜在的TDE。最后提出基于电压相关性和线损平衡的阶梯式归真模型,先通过相关性分析逐级定位TDE隶属的10kV首端大馈线和0.4kV低压台区集,再利用线损贡献度规则溯源其准确的户变关系,实现拓扑数据闭环治理。所提方法已部署至华东某电力公司数据中台,并用八百余个实际台区数据验证校核,识别准确率为97.05%,具备较好的鲁棒性与泛用性。
文摘回顾性分析了美国食品药品监督管理局制造商和用户设施设备体验(Manufacturer and User Facility Device Experience,MAUDE)数据库2021年1月至2024年6月的弹簧圈不良事件,结合山东省内医院调研和专家论证情况指出了弹簧圈在临床使用过程中存在的风险点并进行了原因分析,提出了落实注册人的主体责任、提高使用单位的专业技能、强化监管部门的监管力度等改进措施,为弹簧圈的安全使用提供了参考。
基金supported by the National Natural Science Foundation of China(Number:32060645)The Joint Special Project(Key Project)of Yunnan Province Local Undergraduate University(202101BA070001-036)+2 种基金The Joint Special Project(Surface Project)of Yunnan Province Local Undergraduate University(202101BA070001-172)the Science Research Fund Project for Education Department of Yunnan Province(Numbers:2023Y0876,2023Y0860,2023J0828)the Basic Research Special Project for Science and Technology Department of Yunnan Provincial(Number:202301AU070137).
文摘Soil salinization is a major abiotic stress that hampers plant development and significantly reduces agricultural productivity,posing a serious challenge to global food security.Akebia trifoliata(Thunb.)Koidz,a species within the genus Akebia Decne.,is valued for its use in food,traditionalmedicine,oil production,and as an ornamental plant.Curcumin,widely recognized for its pharmacological properties including anti-cancer,anti-neuroinflammatory,and anti-fibrotic effects,has recently drawn interest for its potential roles in plant stress responses.However,its impact on plant tolerance to saline-alkali stress remains poorly understood.In this study,the effects of curcumin on saline-alkali resistance in A.trifoliata were examined by subjecting plants to a saline-alkali solution containing 150 mmol/L sodium ions(a mixture of Na_(2)SO_(4),Na_(2)CO_(3),and NaHCO_(3)).Curcumin treatment under these stress conditions leads to anatomical improvements in leaf structure.Furthermore,A.trifoliatamaintained a favorable Na^(+)/K^(+)ratio through increased potassium uptake and reduced sodium accumulation.Biochemical analysis revealed elevated levels of proline,soluble sugars,and soluble proteins,along with improved activities of antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),and peroxidase(POD).Similarly,the concentrations of hydrogen peroxide(H_(2)O_(2))and malondialdehyde(MDA)were significantly reduced.Transcriptome analysis under saline-alkali stress conditions showed that curcumin influenced seven keymetabolic pathways annotated in the Kyoto Encyclopedia of Genes and Genomes(KEGG)database,with differentially expressed unigenes primarily enriched in transcription factor families such as MYB,AP2/ERF,NAC,bHLH,and C2C2.Moreover,eight differentially expressed genes(DEGs)associated with plant hormone signal transduction were linked to the auxin and brassinosteroid pathways,critical for cell elongation and plant growth.These findings indicate that curcumin increases saline-alkali stress tolerance in A.trifoliata by modulating physiological,biochemical,and transcriptional responses,ultimately supporting improved growth under adverse conditions.
