Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechan...Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechanisms in stroke remain unknown.Riphenyltetrazolium chloride(TTC)staining was employed to assess cerebral infarct volume.The Morris water maze was used to detect cognitive function.A terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL)assay was performed to detect neuronal apoptosis.展开更多
文摘Neuroin fil ammation contributes to neuronal death in cerebral ischemia.Urolithin A(UA),a gut microbial metabolite of ellagic acid,has emerged as a potential antiinflammatory agent.However,its roles and precise mechanisms in stroke remain unknown.Riphenyltetrazolium chloride(TTC)staining was employed to assess cerebral infarct volume.The Morris water maze was used to detect cognitive function.A terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL)assay was performed to detect neuronal apoptosis.
