目的探究基于集束化的护理方案对重症监护室(intense care unit,ICU)机械通气患者预后的影响。方法选取2023年1月—2023年12月在广州市第十二人民医院ICU内接受机械通气的患者60例,采用随机法将其分为观察组和对照组各30例。对照组行常...目的探究基于集束化的护理方案对重症监护室(intense care unit,ICU)机械通气患者预后的影响。方法选取2023年1月—2023年12月在广州市第十二人民医院ICU内接受机械通气的患者60例,采用随机法将其分为观察组和对照组各30例。对照组行常规ICU护理,观察组在对照组基础上行集束化护理。比较两组患者临床恢复、心理压力、并发症发和护理满意度。结果干预后,观察组机械通气时间、ICU住院时间短于对照组,谵妄发生率、气管插管堵管发生率低于对照组,差异有统计学意义(P<0.05);观察组ICUESS量表各维度得分均低于对照组,差异有统计学意义(P<0.05);观察组患者对护理工作的满意度高于对照组,差异有统计学意义(P<0.05)。结论集束化护理应用于ICU机械通气患者中,有助于减少机械通气时间和ICU住院时间,并且能降低谵妄和气管插管堵管发生率,改善患者心理压力,提高患者对护理的满意度。展开更多
This letter comments on a study linking metabolic dysfunction-associated steatotic liver disease(MASLD),vitamin D3,and severe gastric autonomic neuropathy(diabetic gastric motility disorders)in type 2 diabetes mellitu...This letter comments on a study linking metabolic dysfunction-associated steatotic liver disease(MASLD),vitamin D3,and severe gastric autonomic neuropathy(diabetic gastric motility disorders)in type 2 diabetes mellitus(T2DM).We question the necessity of excluding patients with severe cataract(unable to complete fundus exams),as the focus on T2DM-MASLD correlation may render other T2DM complications less relevant.We emphasize vitamin D3’s multifaceted relevance:It associates with T2DM(high-dose supplementation reduces onset risk),MASLD(serum levels predict risk),smooth muscle function,immunity,and T2DM-related fractures via advanced glycation end products.We propose correlating MASLD severity with vitamin D3 levels and diabetic gastric motility disorders in validation analyses(e.g.,correlation,area under the curve)to refine factor analysis.Additionally,based on the authors’note of vitamin D3-tryptophan metabolism links,we call for deeper integration of metabolic pathways to clarify vitamin D3’s role in smooth muscle electrophysiology,leveraging the team’s prior research insights.展开更多
This letter comments on a study on lipid metabolism,immunity,and lymph node metastasis in esophageal cancer,a clinically relevant topic given lipid-immune crosstalk in tumor progression,to be published by the World Jo...This letter comments on a study on lipid metabolism,immunity,and lymph node metastasis in esophageal cancer,a clinically relevant topic given lipid-immune crosstalk in tumor progression,to be published by the World Journal of Gastrointestinal Surgery.Key concerns include the following:Lack of detailed lipid parameter data[especially low-density lipoprotein(LDL)distribution]to contextualize LDL-metastasis associations,unclear criteria for selecting LDL receptors/LDL receptor-related protein family genes and unexplained exclusion of broader lipid metabolism genes,and a disconnect between the proposed LDL-B lymp-hocyte regulatory hypothesis and literature emphasizing cholesterol’s impact on T cells.We therefore suggest that future research should supplement lipid data,clarify gene selection rationale,and provide direct evidence for LDL-B lympho-cyte interplay,in order to enhance reliability in understanding esophageal cancer lipid-immune regulation.展开更多
文摘目的探究基于集束化的护理方案对重症监护室(intense care unit,ICU)机械通气患者预后的影响。方法选取2023年1月—2023年12月在广州市第十二人民医院ICU内接受机械通气的患者60例,采用随机法将其分为观察组和对照组各30例。对照组行常规ICU护理,观察组在对照组基础上行集束化护理。比较两组患者临床恢复、心理压力、并发症发和护理满意度。结果干预后,观察组机械通气时间、ICU住院时间短于对照组,谵妄发生率、气管插管堵管发生率低于对照组,差异有统计学意义(P<0.05);观察组ICUESS量表各维度得分均低于对照组,差异有统计学意义(P<0.05);观察组患者对护理工作的满意度高于对照组,差异有统计学意义(P<0.05)。结论集束化护理应用于ICU机械通气患者中,有助于减少机械通气时间和ICU住院时间,并且能降低谵妄和气管插管堵管发生率,改善患者心理压力,提高患者对护理的满意度。
基金Supported by Fujian Provincial Science and Technology Innovation Joint Fund Project,No.2024Y9555Youth Research Project of the Science and Technology Plan of Fujian Provincial Health Commission,No.2024QNB005+1 种基金Fujian Provincial Natural Science Foundation Project,No.2024J011124Fujian Provincial Medical Project for Creating Dual High-Quality Development(High Level and High Standard),No.ETK2025004.
文摘This letter comments on a study linking metabolic dysfunction-associated steatotic liver disease(MASLD),vitamin D3,and severe gastric autonomic neuropathy(diabetic gastric motility disorders)in type 2 diabetes mellitus(T2DM).We question the necessity of excluding patients with severe cataract(unable to complete fundus exams),as the focus on T2DM-MASLD correlation may render other T2DM complications less relevant.We emphasize vitamin D3’s multifaceted relevance:It associates with T2DM(high-dose supplementation reduces onset risk),MASLD(serum levels predict risk),smooth muscle function,immunity,and T2DM-related fractures via advanced glycation end products.We propose correlating MASLD severity with vitamin D3 levels and diabetic gastric motility disorders in validation analyses(e.g.,correlation,area under the curve)to refine factor analysis.Additionally,based on the authors’note of vitamin D3-tryptophan metabolism links,we call for deeper integration of metabolic pathways to clarify vitamin D3’s role in smooth muscle electrophysiology,leveraging the team’s prior research insights.
基金Supported by Fujian Provincial Science and Technology Innovation Joint Fund Project,No.2024Y9555Fujian Provincial Natural Science Foundation Project,No.20241011124.
文摘This letter comments on a study on lipid metabolism,immunity,and lymph node metastasis in esophageal cancer,a clinically relevant topic given lipid-immune crosstalk in tumor progression,to be published by the World Journal of Gastrointestinal Surgery.Key concerns include the following:Lack of detailed lipid parameter data[especially low-density lipoprotein(LDL)distribution]to contextualize LDL-metastasis associations,unclear criteria for selecting LDL receptors/LDL receptor-related protein family genes and unexplained exclusion of broader lipid metabolism genes,and a disconnect between the proposed LDL-B lymp-hocyte regulatory hypothesis and literature emphasizing cholesterol’s impact on T cells.We therefore suggest that future research should supplement lipid data,clarify gene selection rationale,and provide direct evidence for LDL-B lympho-cyte interplay,in order to enhance reliability in understanding esophageal cancer lipid-immune regulation.
