A one-pot synthesis of vicinal diamines using indoles,azoles and phenothiazines in a tandem multi-component reaction is developed.The utilization of a copper-iodine co-catalytic system enables the generation of a dive...A one-pot synthesis of vicinal diamines using indoles,azoles and phenothiazines in a tandem multi-component reaction is developed.The utilization of a copper-iodine co-catalytic system enables the generation of a diverse range of vicinal diaminoindoles with good selectivity and moderate to good yields.An attractive aspect of this method is that it can be conducted under mild and environmentally friendly conditions,showcasing its potential as an alternative approach for synthesizing vicinal diamines.Moreover,the use of a multicomponent tandem reaction highlights the power and versatility of such strategies in synthetic chemistry.展开更多
基金the National Natural Science Foundation of China(22201048)the Natural Science Foundation of Guangxi Province(2022GXNSFBA035480)+1 种基金the Specific Research Project of Guangxi for Research Bases and Talents(2022AC21099)the Start-up Fund of Guangxi University(A3040051013)for financial support.
文摘A one-pot synthesis of vicinal diamines using indoles,azoles and phenothiazines in a tandem multi-component reaction is developed.The utilization of a copper-iodine co-catalytic system enables the generation of a diverse range of vicinal diaminoindoles with good selectivity and moderate to good yields.An attractive aspect of this method is that it can be conducted under mild and environmentally friendly conditions,showcasing its potential as an alternative approach for synthesizing vicinal diamines.Moreover,the use of a multicomponent tandem reaction highlights the power and versatility of such strategies in synthetic chemistry.
