Correction to:Opto-Electronic Science https://www.oejournal.org/oes/article/doi/10.29026/oes.2024.230029 published online 21 March 2024.After the publication of this article1,it was brought to our attention that the i...Correction to:Opto-Electronic Science https://www.oejournal.org/oes/article/doi/10.29026/oes.2024.230029 published online 21 March 2024.After the publication of this article1,it was brought to our attention that the inset image and absorption spectrum in Fig.1(b)contained a mistake,probably leading to misunderstandings.The inset image and the absorption spectrum in Fig.1(b)were not based on the specific batch of PbS colloidal quantum dots(CQDs)used in this work.展开更多
This research employs micro-CT scanning technology to analyze the porosity,pore fractal dimension,and spatial variability of sandstone preheated to 600℃ and subsequently cooled in water at varying temperatures(20℃,6...This research employs micro-CT scanning technology to analyze the porosity,pore fractal dimension,and spatial variability of sandstone preheated to 600℃ and subsequently cooled in water at varying temperatures(20℃,60℃,100℃).The study investigates the mechanisms by which various factors influence thermal shock damage,focusing on the effects of cooling water temperature and the boiling phase transition.The objective is to develop a method for characterizing thermal shock damage that considers spatial variability.The findings indicate that thermal shock damage is limited to a shallow depth beneath the surface,with increased severity near the surface.The boiling phase transition significantly enhances the convective heat transfer coefficient,resulting in substantially higher thermal shock damage when cooled with 100℃ boiling water compared to 20℃ and 60℃ water.Furthermore,for the entire specimen,heating damage exceeds thermal shock damage,and the influence of thermal shock diminishes as specimen size increases.This study addresses the limitations of traditional methods for assessing thermal shock damage that disregard spatial variability and provides practical guidance for engineering projects to manage thermal shock damage more effectively.展开更多
The traditional small target detection algorithm often results in a high false alarm rate on the sea surface background. To address this issue, a small target detection method based on guided filtering and local avera...The traditional small target detection algorithm often results in a high false alarm rate on the sea surface background. To address this issue, a small target detection method based on guided filtering and local average gray level difference was proposed in this paper for the sea surface. Firstly, the method enhanced the details of the small targets by employing guided filtering to suppress the background clutter and noise in the sea surface image. Subsequently, the local average gray level difference of each point in the image was calculated to further distinguish the targets from other interference points. Finally, the threshold segmentation method was utilized to obtain the actual small targets on the sea surface. After conducting experiments on various sea surface scenes, the LSCRG, BSF, and ROC curve were computed for the proposed method and five other algorithms. Comparative analysis with BS, Top-hat, TDLMS, Max-median, and LCM demonstrates the superiority of the proposed method for infrared small target detection on the sea surface.展开更多
BACKGROUND:Human amniotic epithelial cells(HAECs)can differentiate into neurons,astrocytes and oligodendrocytes.They biologically secrete many active neurotrophins and have the capacity to metabolize dopamine enzymes....BACKGROUND:Human amniotic epithelial cells(HAECs)can differentiate into neurons,astrocytes and oligodendrocytes.They biologically secrete many active neurotrophins and have the capacity to metabolize dopamine enzymes.These features underlie a theoretical basis for the treatment of Parkinson's disease(PD).OBJECTIVE:To investigate the survival and differentiation of transplanted HAECs in the lateral ventricle of PD model rats,and to explore its effect on circling behavior,as well as levels of dopamine(DA),the metabolite homovanillic acid,dihydroxyphenyl acetic acid,5-hydroxyindoleacetic acid,and 5-hydroxytryptamine in the striatum.DESIGN,TIME AND SETTING:A randomized,controlled,animal study was performed at the Institute of Biochemistry and Cell Biology,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,and Shanghai Celstar Institute of Biotechnology from May 2007 to December 2008.MATERIALS:HAECs were derived from the placental chorion following caesarean delivery at the Shanghai International Matemal and Child Health Hospital.6-hydroxydopamine(6-OHDA),and mouse anti-human Vimentin monoclonal antibody were purchased from Sigma,USA;mouse anti-human nestin and tyrosine hydroxylase(TH)monoclonal antibodies were purchased from Chemicon,USA.METHODS:A total of 114 healthy,adult,Sprague Dawley rats were randomly assigned to two groups:PD model[n=90,stereotactic microinjection of 2μL 6-OHDA(3.5μg/uL)into the striatum]and control(n=24,no treatment).The 51 successful PD model rats were randomly divided into 3 subgroups(n=17):HAEC,PBS,and model.The HAEC and PBS groups were respectively injected with 10μL PBS solution containing 1×10^5/mL HAECs or 10 pL PBS into the lateral ventricle.The model group was not treated.MAIN OUTCOME MEASURES:TH protein expression in the striatum was evaluated by immunohistochemistry 5 weeks after HAEC transplantation.At 10 weeks,HAEC survival in the lateral ventricle was investigated by immunofluorescent staining;differentiation of HAECs in the lateral and third ventricles was examined by TH immunohistochemistry;concentrations of DA,homovanillic acid,dihydroxyphenyl acetic acid,5-hydroxyindoleacetic acid,and 5-hydroxytryptamine in the striatum,as well as DA concentration in the cerebrospinal fluid,were measured with high-performance liquid chromatography-electrochemical detection.Circling behavior of PD model rats was consecutively observed for 10 weeks following intraperitoneal injection of amphetamine 1 week after successful model establishment.RESULTS:tn the HAEC group,the number of TH-positive cells significantly increased in the striatum,and circling behavior significantly decreased,compared with the PBS and model groups(P〈0.01).In addition,monoamine concentrations in the striatum,as well as DA concentrations in the cerebrospinal fluid,significantly increased,compared with the PBS group(P〈0.05-0.01).Moreover,a large number of nestin-,vimentin-,and TH-positive cells were observed in the lateral and third ventricles following HAEC injection.CONCLUSION:HAECs survived for 10 weeks with no overgrowth following transplantation into the lateral ventricle of PD model rats.Moreover,the cells differentiated into dopaminergic neurons,which increased DA secretion.HAEC transplantation improved cycling behavior in PD model rats.展开更多
Molybdenum phosphide(MoP),owing to its abundant reserve and high theoretical capacity,is regarded as a promising anode material for potassium-ion batteries.However,it still suffers from the problems of acute volume ex...Molybdenum phosphide(MoP),owing to its abundant reserve and high theoretical capacity,is regarded as a promising anode material for potassium-ion batteries.However,it still suffers from the problems of acute volume expansion and weak diffusion kinetics.This study reports a simple method to synthesize a composite of molybdenum phosphide and porous carbon(MoP@PC)through simple mixing and annealing treatment.In the MoP@PC,lots of MoP nanodots with an average diameter of about 4 nm uniformly embedded in the petal-like porous carbon.The MoP@PC shows reversible capacities of 330 mAh g^(-1) at100 mA g^(-1) after 100 cycles,and ultra-long cycling stability with a capacity of 240 mAh g^(-1) after 1000 cycles at 1 A g^(-1) and 161 mAh g^(-1) after 1000 cycles at 5 A g^(-1).The structure of MoP@PC after charging-discharging cycles is also investigated by high resolution transmission electron microscope(HRTEM)and the result shows that MoP can still maintain the nanodot morphology without any agglomeration after 1000 cycles at 5 A g^(-1).The storage mechanism of potassium ions was studied as well,which reveals that MoP and potassium ion have a conversion reaction.展开更多
Radio Frequency(RF) technology represents a high-precision relative navigation solution that has significant potential for application to earth-orbiting satellites. In precision applications, multipath errors dominate...Radio Frequency(RF) technology represents a high-precision relative navigation solution that has significant potential for application to earth-orbiting satellites. In precision applications, multipath errors dominate the total error because observables, which are used to estimate carrier-phase integer ambiguity, are not always subject to a Gaussian distribution when dualfrequency ambiguity estimation methods are used in the presence of multipath. As it has been shown that ranging observables obey a Gaussian mixture distribution, this study proposes improvements to the accuracy of estimation based on multipath mitigation founded on the Gaussian mixture model. To this end, such a model is created for integer ambiguity resolution in the presence of multipath, using which the theoretical error in dual-frequency ambiguity estimation is derived.Expectation Maximization(EM), which aids dual-frequency ambiguity estimation, is subsequently proposed to reduce the effect of multipath errors. Finally, two experimental scenarios are implemented to test the performance of the proposed method. The results show that EM-aided dualfrequency ambiguity estimation reduces the range error to approximately 20% in comparison with simple dual-frequency ambiguity estimation. Therefore the proposed technique is effective for multipath mitigation in RF relative measurement.展开更多
The Na^(+)/vacancy ordering can effectively affect the electrochemical behavior of P2-type cathode material.In this work we proposed an integrated strategy by attaining a high Na content,In^(3+) doping in conjunction ...The Na^(+)/vacancy ordering can effectively affect the electrochemical behavior of P2-type cathode material.In this work we proposed an integrated strategy by attaining a high Na content,In^(3+) doping in conjunction with NaInO_(2) coating in the P2-Na_(0.75)Mn_(0.67)Ni_(0.33)O_(2) which can inhibit the sodium vacancy order,smooth the electrochemical curve,and enhance the structural stability and rate capability.A combination of X-ray diffraction analysis and DFT calculation indicate that the In(3+) ions in the Na layer serve as"pillars”to stabilize the layered structure,especially for high current density charging.The P2-Na_(0.75)Mn_(0.67)Ni_(0.33)In_(0.02)O_(2) with an impressive sodium content exhibits a remarkable reversible capacity of 109.6 mAh g^(-1),superior rate capability capacity of 79.8 mAh g^(-1)at 20 C,and 85%capacity retention after 100 cycles at 5 C.This work demonstrates an efficient approach for the comprehensive optimization of sodium ion cathode materials.展开更多
Zinc-based degradable metals are considered one of the most promising biodegradable materials due to their moderate corrosion rate,excellent mechanical properties,and good biocompatibility.In this work,biodegradable Z...Zinc-based degradable metals are considered one of the most promising biodegradable materials due to their moderate corrosion rate,excellent mechanical properties,and good biocompatibility.In this work,biodegradable Zn-0.4Mn-0.8Li alloy was fabricated and rolled in multiple passes at different tem peratures.As the hot rolling temperature increases,the grain size of Zn-0.4Mn-0.8Li alloy was found to increase cor-respondingly.Further,a multi-scale structure with the coexistence of coarse grains and fine grains was obtained.The results demonstrated that the mechanical strength and corrosion resistance were improved by increasing the rolled temperature.It was observed that Zn-0.4Mn-0.8Li alloy with a total reduction of 90%after hot rolling at 325℃ exhibited excellent mechanical and corrosion properties.The cooperation of multi-scale microstructure and twinning was found to improve the strength and guarantee the duc-tility of Zn-0.4Mn-0.8Li alloy significantly so that the 325℃ hot-rolled Zn-0.4Mn-0.8Li alloy has optimal comprehensive properties.Further,yield strength,ultimate tensile strength,and elongation were found to be 449.7±5.3 MPa,505.1±6.5 MPa,and 40.5%±7.5%,respectively.Meanwhile,Zn-0.4Mn-0.8Li al-loy via 325℃ hot-rolled processes also exhibited excellent corrosion resistance.The corrosion current density and corrosion potential were found to be 8.8×10-5 mA cm^(-2)and−0.929 V,respectively.The preliminary study indicates that Zn-0.4Mn-0.8Li alloy is a promising candidate material for medical de-vice applications.展开更多
Quantum dot-based up-conversion photodetector,in which an infrared photodiode(PD)and a quantum dot light-emitting diode(QLED)are back-to-back connected,is a promising candidate for low-cost infrared imaging.However,th...Quantum dot-based up-conversion photodetector,in which an infrared photodiode(PD)and a quantum dot light-emitting diode(QLED)are back-to-back connected,is a promising candidate for low-cost infrared imaging.However,the huge efficiency losses caused by integrating the PD and QLED together hasn’t been studied sufficiently.This work revealed at least three origins for the efficiency losses.First,the PD unit and QLED unit usually didn’t work under optimal conditions at the same time.Second,the potential barriers and traps at the interconnection between PD and QLED units induced unfavorable carrier recombination.Third,much emitted visible light was lost due to the strong visible absorption in the PD unit.Based on the understandings on the loss mechanisms,the infrared up-conversion photodetectors were optimized and achieved a breakthrough photon-to-photon conversion efficiency of 6.9%.This study provided valuable guidance on how to optimize the way of integration for up-conversion photodetectors.展开更多
The contradiction between the strength and ductility of metallic materials is a major scientific problemthat has been researched for a long time. Dual-phase equiatomic and non-equiatomic Ti-Zr-Nb-Ta highentropy alloys...The contradiction between the strength and ductility of metallic materials is a major scientific problemthat has been researched for a long time. Dual-phase equiatomic and non-equiatomic Ti-Zr-Nb-Ta highentropy alloys (HEAs) with super-high strength and excellent ductility have been successfully developedvia mechanical alloying (MA) combined with spark plasma sintering (SPS) technology. This is adjustedby altering the atomic ratios of the different phases. X-ray diffraction (XRD) and transmission electronmicroscopy (TEM) were performed to confirm the dual-phase microstructure. After the SPS process, theaverage grain size of the aforementioned equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs (134 ± 50 nm) evaluated byelectron back-scattering diffraction (EBSD) is smaller than that of the Ti-Zr-Nb-Ta HEAs (150 μm), whichwere fabricated using arc melting. According to the Hall-Petch formula, the grain boundary strengthening contribution in the Ti-Zr-Nb-Ta system is 33-fold higher than those fabricated using the arc-meltingprocess. When the alloy phase comprises the equivalent dual-phase, equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAshave good comprehensive performance compared to non-equiatomic Ti-Zr-Nb-Ta HEAs prepared usingthe same process. The yield strength of equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs (2212 ± 38 MPa) is two-foldhigher than that of Ti-Zr-Nb-Ta HEAs (1100 ± 90 MPa) fabricated via arc melting. This can be attributed tothe ultra-fine grain size. Notably, the equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs possess approximately the samebiocompatibility as commercial pure Ti (CP-Ti), indicating that the equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs areprovided with a possibility as an advanced biomaterial for the applications of the medical field.展开更多
O3-type layered oxide cathodes have been widely investigated due to their high reversible capacities and sufficient Na+reservoirs.However,such materials usually suffer from complex multistep phase transitions along wi...O3-type layered oxide cathodes have been widely investigated due to their high reversible capacities and sufficient Na+reservoirs.However,such materials usually suffer from complex multistep phase transitions along with drastic volume changes,leading to the unsatisfied cycle performance.Herein,we report a Mg/Ti co-doped O3-type NaNi_(0.5)Mn_(0.5)O_(2),which can effectively suppress the complex multistep phase transition and realize a solid-solution reaction within a wide voltage range.It is confirmed that,the Mg/Ti co-doping is beneficial to enhance the structural stability and integrity by absorbing micro-strain and distortions.Thus,the as obtained sample delivers an outstanding cyclic performance(82.3%after 200 cycles at 1 C)in the voltage range of 2.0-4.0 V,and a high discharge capacity of 86.6 mAh/g after 100 cycles within the wide voltage range(2.0-4.5 V),which outperform the existing literatures.This co-doping strategy offers new insights into high performance O3-type cathode for sodium ion batteries.展开更多
Dysregulation of cytoskeletal proteins has been found in response to DNA damage stress,yet the functional role of cytoskeletal proteins in DNA repair remained unexplored.Here,we found that DNA-damaging agents induced ...Dysregulation of cytoskeletal proteins has been found in response to DNA damage stress,yet the functional role of cytoskeletal proteins in DNA repair remained unexplored.Here,we found that DNA-damaging agents induced substantial upregulation of smooth muscle-specific cytoskeletal protein smoothelin(SMTN)in colorectal cancer(CRC)cells.Silencing SMTN abrogated G2/M arrest,exacerbated DNA damage,and markedly enhanced the chemosensitivity of CRC cells to various DNA-damaging agents.Notably,SMTN could rapidly accumulate at DNA damage sites within 1 min after laser irradiation,which was indispensable for the initiation of homologous recombination(HR)repair.Mechanistically,SMTN stabilized RAD51 by disrupting its interaction with its E3 ubiquitin ligase HUWE1,thereby maintaining the process of HR repair.To explore the therapeutic role of SMTN,customized cell membrane infused biomimetic liposomes were constructed to ensure rapid delivery of SMTN siRNA specifically into HCT-116 cells,yielding significantly enhanced anti-cancer effects of irinotecan and fuzuloparib both in vitro and in vivo.To summarize,our findings revealed a novel function of SMTN in DNA damage repair and provided a therapeutic strategy of targeting SMTN to enhance the efficacy of DNA damage agents.展开更多
Background:Malaria remains a global health challenge,with 249 million cases and 608,000 deaths reported in 2022.While China achieved malaria elimination,imported cases surged by 194.4% in 2023,underscoring the need fo...Background:Malaria remains a global health challenge,with 249 million cases and 608,000 deaths reported in 2022.While China achieved malaria elimination,imported cases surged by 194.4% in 2023,underscoring the need for rapid diagnostics.Traditional methods like microscopy and rapid diagnostic tests(RDTs)face limitations in sensitivity and infrastructure requirements.This study aimed to establish and optimize a“one-pot”enzymatic recombinase amplification(ERA)assay for the molecular detection of Plasmodium falciparum and Plasmodium vivax,and to evaluate the efficacy of this assay through methodological verification and clinical performance.Methods:We designed a specific ERA assay targeting the conserved regions of P.falciparum and P.vivax genetic material.We evaluated the sensitivity and specificity of this assay using synthetic plasmids and genomic material.Additionally,we tested the stability of the reaction by incorporating potential interfering substances into the reaction system.Finally,we analyzed the detection performance of the ERA method against real-time fluorescent quantitative PCR and rapid diagnostic tests using clinical samples.Results:The detection process could be completed within 25 min at 35℃-40℃,and the results could be interpreted either under UV light or using a GeneScope instrument.The detection limit of the ERA assay was 250 copies/mL,which was 40 times more sensitive than fluorescent quantitative PCR.When evaluating the clinical performance using 75 clinical specimens,the detection rate of the ERA method was 94.54% compared with 89.09% for fluorescent quantitative PCR.The ERA assay and fluorescent quantitative PCR can achieve positive detection when blood samples were diluted 1024 times or even 4096 times.Comparatively,the detection capabilities of rapid diagnostic tests were significantly lower than that of the ERA assay.Conclusion:The ERA method shows good performance in the detection of P.falciparum and P.vivax,and can be used as a complementary tool for malaria screening and clinical diagnosis.展开更多
Objective To design and synthesize an amount of butyrolactone V derivatives,evaluate the anti-inflammatory effects of all the derivatives,look for potential drugs that inhibit inflammatory bowel disease(IBD),and deter...Objective To design and synthesize an amount of butyrolactone V derivatives,evaluate the anti-inflammatory effects of all the derivatives,look for potential drugs that inhibit inflammatory bowel disease(IBD),and determine the structure-activity relationship(SAR).Methods The butyrolactone V derivatives were synthesized with high yield by oxidation reaction,substitution reaction,and esterification reaction in sequence,and the production of nitric oxide was assessed in RAW264.7 cells treated with the lipopolysaccharide and the compounds.Then,the target compounds were studied for their activity in dextran sodium sulfate(DSS)-induced ulcerative colitis.Results A total of three series of compounds encompassing 60 derivatives of the natural product butyrolactone V were designed and synthesized.The results showed that compounds 5p and 7e could alleviate the symptoms of DSS-induced colitis in mice,including alleviating diarrhea,inhibiting the reduction of colon length,and reducing tissue damage.The preliminary mechanism exploration indicated that compounds 5p and 7e could improve the symptoms of IBD in mice mainly by reducing the expression of chemokines and exerting anti-inflammatory effects.Conclusion This study reports the synthesis and the derivatization of butyrolactone V and analysis on anti-inflammatory activity.The most effective compounds 5p and 7e have the potential to be further developed as drugs to treat IBD.展开更多
Nuclear power development is a complex issue spanning cyber,physical,and social systems that is essential to achieving energy security and climate goals.With the ongoing worldwide trend towards carbon neutrality,the p...Nuclear power development is a complex issue spanning cyber,physical,and social systems that is essential to achieving energy security and climate goals.With the ongoing worldwide trend towards carbon neutrality,the positioning of nuclear power in energy mix should be reconsidered.This paper aims to present a systematic review of current research on optimization of nuclear power development.The concept of cyber-physical-social system in energy(CPSSE)is adopted,which provides a suitable perspective and enables the review of relevant studies to achieve some novel insights.Based on the CPSSE,firstly,a research framework is established and the main research elements in optimization are identified,followed by a proposed conceptual risk-based optimization model.Secondly,current studies are analyzed and classified into four categories according to the research boundary.The status quo and limitations are discussed.It is found that the research results of nuclear-specific issues have not been well integrated into the optimization of nuclear power.As a relatively reliable power supply,nuclear power is capable of maintaining power and electricity adequacy of the whole system,especially in the case of power shortage caused by long-period low output of renewable energy or extreme external disasters.This superiority should not be ignored in the optimization.Other critical factors that should be further considered include disruptive technologies,nuclear safety,energy policies,and stakeholder behaviors.Finally,suggestions are given for future research.展开更多
Suppressor of G2 allele of skp1(SGT1)is a highly conserved eukaryotic protein that plays a vital role in growth,development,and immunity in both animals and plants.Although some SGT1 interactors have been identified,t...Suppressor of G2 allele of skp1(SGT1)is a highly conserved eukaryotic protein that plays a vital role in growth,development,and immunity in both animals and plants.Although some SGT1 interactors have been identified,the molecular regulatory network of SGT1 remains unclear.SGT1 serves as a co-chaperone to stabilize protein complexes such as the nucleotide-binding leucine-rich repeat(NLR)class of immune receptors,thereby positively regulating plant immunity.SGT1 has also been found to be asso-ciated with the SKP1-Cullin-F-box(SCF)E3 ubiquitin ligase complex.However,whether SGT1 targets im-mune repressors to coordinate plant immune activation remains elusive.In this study,we constructed a toolbox for TurbolD-and split-TurbolD-based proximity labeling(PL)assays in Nicotiana benthamiana and used the PL toolbox to explore the SGT1 interactome during pre-and post-immune activation.The comprehensive SGT1 interactome network we identified highlights a dynamic shift from proteins associ-ated with plant development to those linked with plant immune responses.We found that SGT1 interacts with Necrotic Spotted Lesion1(NSL1),which negatively regulates salicylic acid-mediated defenseby inter-fering with the nucleocytoplasmic trafficking of non-expressor of pathogenesis-related genes 1(NPR1)during N NLR-mediated response to tobacco mosaic virus.SGT1 promotes the SCF-dependent degrada-tion of NSL1 to facilitate immune activation,while salicylate-induced protein kinase-mediated phosphory-lation of SGT1further potentiates this process.Besides NNLR,NSL1also functions in several other NLR-mediated immunity.Collectively,our study unveils the regulatory landscape of SGT1 and reveals a novel SGT1-NSL1 signaling module that orchestrates plant innate immunity.展开更多
Antimony-based Zintl compounds AM2Sb2(A=Ca,Sr,Ba,Yb,Eu;M=Mg,Zn,Cd,Mn),which enable a broad range of manipulation on electrical and thermal transport properties,are considered as an important class of thermoelectric ma...Antimony-based Zintl compounds AM2Sb2(A=Ca,Sr,Ba,Yb,Eu;M=Mg,Zn,Cd,Mn),which enable a broad range of manipulation on electrical and thermal transport properties,are considered as an important class of thermoelectric materials.Phonon and carrier transport engineering were realized in YbMg2Sb2 via equivalent and aliovalent substitution of Zn and Ag,respectively.The roomtemperature thermal conductivity reduces from 1.96 to 1.15 W m^-1 K^-1 for YbMg2-xZnxSb2 due to the mass and strain fluctuation through the formation of the absolute solid solution of YbMg2Sb2-YbZn2Sb2.Furthermore,the carrier concentration has been further optimized by Ag doping(from 0.42×10^19 to 7.72×10^19 cm^-3 at room temperature),and thus the electrical conductivity and the power factor are enhanced effectively.The integrated aspects make the dimensionless figure of merit(zT)reach 0.48 at 703 K,which is 60%higher than the pristine YbMgZnSb2 sample.展开更多
文摘Correction to:Opto-Electronic Science https://www.oejournal.org/oes/article/doi/10.29026/oes.2024.230029 published online 21 March 2024.After the publication of this article1,it was brought to our attention that the inset image and absorption spectrum in Fig.1(b)contained a mistake,probably leading to misunderstandings.The inset image and the absorption spectrum in Fig.1(b)were not based on the specific batch of PbS colloidal quantum dots(CQDs)used in this work.
基金financially supported by the National Natural Science Foundation of China(Grant No.51874207)the Natural Science Foundation of Shanxi Province(Grant Nos.202303021211042 and 202303011222006).
文摘This research employs micro-CT scanning technology to analyze the porosity,pore fractal dimension,and spatial variability of sandstone preheated to 600℃ and subsequently cooled in water at varying temperatures(20℃,60℃,100℃).The study investigates the mechanisms by which various factors influence thermal shock damage,focusing on the effects of cooling water temperature and the boiling phase transition.The objective is to develop a method for characterizing thermal shock damage that considers spatial variability.The findings indicate that thermal shock damage is limited to a shallow depth beneath the surface,with increased severity near the surface.The boiling phase transition significantly enhances the convective heat transfer coefficient,resulting in substantially higher thermal shock damage when cooled with 100℃ boiling water compared to 20℃ and 60℃ water.Furthermore,for the entire specimen,heating damage exceeds thermal shock damage,and the influence of thermal shock diminishes as specimen size increases.This study addresses the limitations of traditional methods for assessing thermal shock damage that disregard spatial variability and provides practical guidance for engineering projects to manage thermal shock damage more effectively.
文摘The traditional small target detection algorithm often results in a high false alarm rate on the sea surface background. To address this issue, a small target detection method based on guided filtering and local average gray level difference was proposed in this paper for the sea surface. Firstly, the method enhanced the details of the small targets by employing guided filtering to suppress the background clutter and noise in the sea surface image. Subsequently, the local average gray level difference of each point in the image was calculated to further distinguish the targets from other interference points. Finally, the threshold segmentation method was utilized to obtain the actual small targets on the sea surface. After conducting experiments on various sea surface scenes, the LSCRG, BSF, and ROC curve were computed for the proposed method and five other algorithms. Comparative analysis with BS, Top-hat, TDLMS, Max-median, and LCM demonstrates the superiority of the proposed method for infrared small target detection on the sea surface.
基金Supported by:the Major State Basic Research Development Program of China(973 Program),No.2005CB522604the National Natural Science Foundation of China,No.30271325
文摘BACKGROUND:Human amniotic epithelial cells(HAECs)can differentiate into neurons,astrocytes and oligodendrocytes.They biologically secrete many active neurotrophins and have the capacity to metabolize dopamine enzymes.These features underlie a theoretical basis for the treatment of Parkinson's disease(PD).OBJECTIVE:To investigate the survival and differentiation of transplanted HAECs in the lateral ventricle of PD model rats,and to explore its effect on circling behavior,as well as levels of dopamine(DA),the metabolite homovanillic acid,dihydroxyphenyl acetic acid,5-hydroxyindoleacetic acid,and 5-hydroxytryptamine in the striatum.DESIGN,TIME AND SETTING:A randomized,controlled,animal study was performed at the Institute of Biochemistry and Cell Biology,Shanghai Institute for Biological Sciences,Chinese Academy of Sciences,and Shanghai Celstar Institute of Biotechnology from May 2007 to December 2008.MATERIALS:HAECs were derived from the placental chorion following caesarean delivery at the Shanghai International Matemal and Child Health Hospital.6-hydroxydopamine(6-OHDA),and mouse anti-human Vimentin monoclonal antibody were purchased from Sigma,USA;mouse anti-human nestin and tyrosine hydroxylase(TH)monoclonal antibodies were purchased from Chemicon,USA.METHODS:A total of 114 healthy,adult,Sprague Dawley rats were randomly assigned to two groups:PD model[n=90,stereotactic microinjection of 2μL 6-OHDA(3.5μg/uL)into the striatum]and control(n=24,no treatment).The 51 successful PD model rats were randomly divided into 3 subgroups(n=17):HAEC,PBS,and model.The HAEC and PBS groups were respectively injected with 10μL PBS solution containing 1×10^5/mL HAECs or 10 pL PBS into the lateral ventricle.The model group was not treated.MAIN OUTCOME MEASURES:TH protein expression in the striatum was evaluated by immunohistochemistry 5 weeks after HAEC transplantation.At 10 weeks,HAEC survival in the lateral ventricle was investigated by immunofluorescent staining;differentiation of HAECs in the lateral and third ventricles was examined by TH immunohistochemistry;concentrations of DA,homovanillic acid,dihydroxyphenyl acetic acid,5-hydroxyindoleacetic acid,and 5-hydroxytryptamine in the striatum,as well as DA concentration in the cerebrospinal fluid,were measured with high-performance liquid chromatography-electrochemical detection.Circling behavior of PD model rats was consecutively observed for 10 weeks following intraperitoneal injection of amphetamine 1 week after successful model establishment.RESULTS:tn the HAEC group,the number of TH-positive cells significantly increased in the striatum,and circling behavior significantly decreased,compared with the PBS and model groups(P〈0.01).In addition,monoamine concentrations in the striatum,as well as DA concentrations in the cerebrospinal fluid,significantly increased,compared with the PBS group(P〈0.05-0.01).Moreover,a large number of nestin-,vimentin-,and TH-positive cells were observed in the lateral and third ventricles following HAEC injection.CONCLUSION:HAECs survived for 10 weeks with no overgrowth following transplantation into the lateral ventricle of PD model rats.Moreover,the cells differentiated into dopaminergic neurons,which increased DA secretion.HAEC transplantation improved cycling behavior in PD model rats.
基金supported by the National Natural Science Foundation of China(Grant Nos.51974114,51672075 and 21908049)Natural Science Foundation of Hunan Province(Grant No.2020JJ4175)the Fundamental Research Funds for the Central Universities。
文摘Molybdenum phosphide(MoP),owing to its abundant reserve and high theoretical capacity,is regarded as a promising anode material for potassium-ion batteries.However,it still suffers from the problems of acute volume expansion and weak diffusion kinetics.This study reports a simple method to synthesize a composite of molybdenum phosphide and porous carbon(MoP@PC)through simple mixing and annealing treatment.In the MoP@PC,lots of MoP nanodots with an average diameter of about 4 nm uniformly embedded in the petal-like porous carbon.The MoP@PC shows reversible capacities of 330 mAh g^(-1) at100 mA g^(-1) after 100 cycles,and ultra-long cycling stability with a capacity of 240 mAh g^(-1) after 1000 cycles at 1 A g^(-1) and 161 mAh g^(-1) after 1000 cycles at 5 A g^(-1).The structure of MoP@PC after charging-discharging cycles is also investigated by high resolution transmission electron microscope(HRTEM)and the result shows that MoP can still maintain the nanodot morphology without any agglomeration after 1000 cycles at 5 A g^(-1).The storage mechanism of potassium ions was studied as well,which reveals that MoP and potassium ion have a conversion reaction.
基金supported by the National Natural Science Foundation of China(No.91438116)the Program for New Century Excellent Talents of China(No.NCET-12-0030)
文摘Radio Frequency(RF) technology represents a high-precision relative navigation solution that has significant potential for application to earth-orbiting satellites. In precision applications, multipath errors dominate the total error because observables, which are used to estimate carrier-phase integer ambiguity, are not always subject to a Gaussian distribution when dualfrequency ambiguity estimation methods are used in the presence of multipath. As it has been shown that ranging observables obey a Gaussian mixture distribution, this study proposes improvements to the accuracy of estimation based on multipath mitigation founded on the Gaussian mixture model. To this end, such a model is created for integer ambiguity resolution in the presence of multipath, using which the theoretical error in dual-frequency ambiguity estimation is derived.Expectation Maximization(EM), which aids dual-frequency ambiguity estimation, is subsequently proposed to reduce the effect of multipath errors. Finally, two experimental scenarios are implemented to test the performance of the proposed method. The results show that EM-aided dualfrequency ambiguity estimation reduces the range error to approximately 20% in comparison with simple dual-frequency ambiguity estimation. Therefore the proposed technique is effective for multipath mitigation in RF relative measurement.
基金supported by the National Natural Science Foundation of China (22179077, 51774251)the Shanghai Science and Technology Commission’s “2020 Science and Technology Innovation Action Plan” (20511104003)+2 种基金the Natural Science Foundation in Shanghai (21ZR1424200)the Hebei Natural Science Foundation for Distinguished Young Scholars (B2017203313)the Scientific Research Foundation for the Returned Overseas Chinese Scholars (CG2014003002)。
文摘The Na^(+)/vacancy ordering can effectively affect the electrochemical behavior of P2-type cathode material.In this work we proposed an integrated strategy by attaining a high Na content,In^(3+) doping in conjunction with NaInO_(2) coating in the P2-Na_(0.75)Mn_(0.67)Ni_(0.33)O_(2) which can inhibit the sodium vacancy order,smooth the electrochemical curve,and enhance the structural stability and rate capability.A combination of X-ray diffraction analysis and DFT calculation indicate that the In(3+) ions in the Na layer serve as"pillars”to stabilize the layered structure,especially for high current density charging.The P2-Na_(0.75)Mn_(0.67)Ni_(0.33)In_(0.02)O_(2) with an impressive sodium content exhibits a remarkable reversible capacity of 109.6 mAh g^(-1),superior rate capability capacity of 79.8 mAh g^(-1)at 20 C,and 85%capacity retention after 100 cycles at 5 C.This work demonstrates an efficient approach for the comprehensive optimization of sodium ion cathode materials.
基金The work was financially supported by the National Natural Science Foundation of China(No.51871077)the Guangdong Basic and Applied Basic Research Foundation(No.2021A1515012626)+1 种基金the Shenzhen Knowledge Innovation Plan-Fundamental Research(Discipline Distribution)(No.JCYJ20180507184623297)the Startup Foundation from Shenzhen and Startup Foundation from Harbin Institute of Technology(Shenzhen),and the Development and Reform Commission of Shenzhen Municipality Shenzhen R&D Center for Al-based Hydrogen Hydrolysis Materials(No.ZX20190229).
文摘Zinc-based degradable metals are considered one of the most promising biodegradable materials due to their moderate corrosion rate,excellent mechanical properties,and good biocompatibility.In this work,biodegradable Zn-0.4Mn-0.8Li alloy was fabricated and rolled in multiple passes at different tem peratures.As the hot rolling temperature increases,the grain size of Zn-0.4Mn-0.8Li alloy was found to increase cor-respondingly.Further,a multi-scale structure with the coexistence of coarse grains and fine grains was obtained.The results demonstrated that the mechanical strength and corrosion resistance were improved by increasing the rolled temperature.It was observed that Zn-0.4Mn-0.8Li alloy with a total reduction of 90%after hot rolling at 325℃ exhibited excellent mechanical and corrosion properties.The cooperation of multi-scale microstructure and twinning was found to improve the strength and guarantee the duc-tility of Zn-0.4Mn-0.8Li alloy significantly so that the 325℃ hot-rolled Zn-0.4Mn-0.8Li alloy has optimal comprehensive properties.Further,yield strength,ultimate tensile strength,and elongation were found to be 449.7±5.3 MPa,505.1±6.5 MPa,and 40.5%±7.5%,respectively.Meanwhile,Zn-0.4Mn-0.8Li al-loy via 325℃ hot-rolled processes also exhibited excellent corrosion resistance.The corrosion current density and corrosion potential were found to be 8.8×10-5 mA cm^(-2)and−0.929 V,respectively.The preliminary study indicates that Zn-0.4Mn-0.8Li alloy is a promising candidate material for medical de-vice applications.
基金supported by the following research fundings including:the National Natural Science Foundation of China(Nos.62005114,62204078 and U22A2072)Natural Science Foundation of Henan-Excellent Youth Scholar(No.232300421092)Open Fund of the State Key Laboratory of Integrated Optoelectronics+(IOSKL2020KF01).
文摘Quantum dot-based up-conversion photodetector,in which an infrared photodiode(PD)and a quantum dot light-emitting diode(QLED)are back-to-back connected,is a promising candidate for low-cost infrared imaging.However,the huge efficiency losses caused by integrating the PD and QLED together hasn’t been studied sufficiently.This work revealed at least three origins for the efficiency losses.First,the PD unit and QLED unit usually didn’t work under optimal conditions at the same time.Second,the potential barriers and traps at the interconnection between PD and QLED units induced unfavorable carrier recombination.Third,much emitted visible light was lost due to the strong visible absorption in the PD unit.Based on the understandings on the loss mechanisms,the infrared up-conversion photodetectors were optimized and achieved a breakthrough photon-to-photon conversion efficiency of 6.9%.This study provided valuable guidance on how to optimize the way of integration for up-conversion photodetectors.
基金The work was financially supported by the National Natural Science Foundation of China(No.51871077)the Guangdong Basic and Applied Basic Research Foundation(No.2021A1515012626)+3 种基金the Shenzhen Knowledge Innovation Plan-Fundamental Research(Discipline Distribution)(No.JCYJ20180507184623297)the Shenzhen Science and Technology Plan-Technology Innovation(No.KQJSCX20180328165656256)the Development and Reform Commission of Shenzhen Municipality-Shenzhen R&D Center for Albased Hydrogen Hydrolysis Materials(No.ZX20190229)the Startup Foundation from Shenzhen and Startup Foundation from Harbin Institute of Technology(Shenzhen).
文摘The contradiction between the strength and ductility of metallic materials is a major scientific problemthat has been researched for a long time. Dual-phase equiatomic and non-equiatomic Ti-Zr-Nb-Ta highentropy alloys (HEAs) with super-high strength and excellent ductility have been successfully developedvia mechanical alloying (MA) combined with spark plasma sintering (SPS) technology. This is adjustedby altering the atomic ratios of the different phases. X-ray diffraction (XRD) and transmission electronmicroscopy (TEM) were performed to confirm the dual-phase microstructure. After the SPS process, theaverage grain size of the aforementioned equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs (134 ± 50 nm) evaluated byelectron back-scattering diffraction (EBSD) is smaller than that of the Ti-Zr-Nb-Ta HEAs (150 μm), whichwere fabricated using arc melting. According to the Hall-Petch formula, the grain boundary strengthening contribution in the Ti-Zr-Nb-Ta system is 33-fold higher than those fabricated using the arc-meltingprocess. When the alloy phase comprises the equivalent dual-phase, equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAshave good comprehensive performance compared to non-equiatomic Ti-Zr-Nb-Ta HEAs prepared usingthe same process. The yield strength of equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs (2212 ± 38 MPa) is two-foldhigher than that of Ti-Zr-Nb-Ta HEAs (1100 ± 90 MPa) fabricated via arc melting. This can be attributed tothe ultra-fine grain size. Notably, the equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs possess approximately the samebiocompatibility as commercial pure Ti (CP-Ti), indicating that the equiatomic Ti_(25)Zr_(25)Nb_(25)Ta_(25) HEAs areprovided with a possibility as an advanced biomaterial for the applications of the medical field.
基金supported by the National Natural Science Foundation of China(Nos.22179077,51774251,21908142)Shanghai Science and Technology Commission’s“2020 Science and Technology In-novation Action Plan”(No.20511104003)Natural Science Foundation in Shanghai(No.21ZR1424200)。
文摘O3-type layered oxide cathodes have been widely investigated due to their high reversible capacities and sufficient Na+reservoirs.However,such materials usually suffer from complex multistep phase transitions along with drastic volume changes,leading to the unsatisfied cycle performance.Herein,we report a Mg/Ti co-doped O3-type NaNi_(0.5)Mn_(0.5)O_(2),which can effectively suppress the complex multistep phase transition and realize a solid-solution reaction within a wide voltage range.It is confirmed that,the Mg/Ti co-doping is beneficial to enhance the structural stability and integrity by absorbing micro-strain and distortions.Thus,the as obtained sample delivers an outstanding cyclic performance(82.3%after 200 cycles at 1 C)in the voltage range of 2.0-4.0 V,and a high discharge capacity of 86.6 mAh/g after 100 cycles within the wide voltage range(2.0-4.5 V),which outperform the existing literatures.This co-doping strategy offers new insights into high performance O3-type cathode for sodium ion batteries.
基金supported by National Natural Science Foundation(82073297,China)Department of Science and Technology of Zhejiang Province Key R&D Projects(2022C03155 and 2023C03112,China)+2 种基金Zhejiang Provincial Program for the Cultivation of High-level Leading Health Talents(2020-18,China)Clinical Pharmacy of Hangzhou Medical Key Discipline(2021-21-16,China)Huzhou City Public Application Research Project(2019GYB63,China)。
文摘Dysregulation of cytoskeletal proteins has been found in response to DNA damage stress,yet the functional role of cytoskeletal proteins in DNA repair remained unexplored.Here,we found that DNA-damaging agents induced substantial upregulation of smooth muscle-specific cytoskeletal protein smoothelin(SMTN)in colorectal cancer(CRC)cells.Silencing SMTN abrogated G2/M arrest,exacerbated DNA damage,and markedly enhanced the chemosensitivity of CRC cells to various DNA-damaging agents.Notably,SMTN could rapidly accumulate at DNA damage sites within 1 min after laser irradiation,which was indispensable for the initiation of homologous recombination(HR)repair.Mechanistically,SMTN stabilized RAD51 by disrupting its interaction with its E3 ubiquitin ligase HUWE1,thereby maintaining the process of HR repair.To explore the therapeutic role of SMTN,customized cell membrane infused biomimetic liposomes were constructed to ensure rapid delivery of SMTN siRNA specifically into HCT-116 cells,yielding significantly enhanced anti-cancer effects of irinotecan and fuzuloparib both in vitro and in vivo.To summarize,our findings revealed a novel function of SMTN in DNA damage repair and provided a therapeutic strategy of targeting SMTN to enhance the efficacy of DNA damage agents.
基金supported by a National Key Research and Development Plan Project(2021YFC2301801).
文摘Background:Malaria remains a global health challenge,with 249 million cases and 608,000 deaths reported in 2022.While China achieved malaria elimination,imported cases surged by 194.4% in 2023,underscoring the need for rapid diagnostics.Traditional methods like microscopy and rapid diagnostic tests(RDTs)face limitations in sensitivity and infrastructure requirements.This study aimed to establish and optimize a“one-pot”enzymatic recombinase amplification(ERA)assay for the molecular detection of Plasmodium falciparum and Plasmodium vivax,and to evaluate the efficacy of this assay through methodological verification and clinical performance.Methods:We designed a specific ERA assay targeting the conserved regions of P.falciparum and P.vivax genetic material.We evaluated the sensitivity and specificity of this assay using synthetic plasmids and genomic material.Additionally,we tested the stability of the reaction by incorporating potential interfering substances into the reaction system.Finally,we analyzed the detection performance of the ERA method against real-time fluorescent quantitative PCR and rapid diagnostic tests using clinical samples.Results:The detection process could be completed within 25 min at 35℃-40℃,and the results could be interpreted either under UV light or using a GeneScope instrument.The detection limit of the ERA assay was 250 copies/mL,which was 40 times more sensitive than fluorescent quantitative PCR.When evaluating the clinical performance using 75 clinical specimens,the detection rate of the ERA method was 94.54% compared with 89.09% for fluorescent quantitative PCR.The ERA assay and fluorescent quantitative PCR can achieve positive detection when blood samples were diluted 1024 times or even 4096 times.Comparatively,the detection capabilities of rapid diagnostic tests were significantly lower than that of the ERA assay.Conclusion:The ERA method shows good performance in the detection of P.falciparum and P.vivax,and can be used as a complementary tool for malaria screening and clinical diagnosis.
基金funded by the National Natural Science Foundation of China(Nos.81725021,81903461,and 82173705)the Natural Science Foundation of Hubei Province,China(No.ZRMS2023000340).
文摘Objective To design and synthesize an amount of butyrolactone V derivatives,evaluate the anti-inflammatory effects of all the derivatives,look for potential drugs that inhibit inflammatory bowel disease(IBD),and determine the structure-activity relationship(SAR).Methods The butyrolactone V derivatives were synthesized with high yield by oxidation reaction,substitution reaction,and esterification reaction in sequence,and the production of nitric oxide was assessed in RAW264.7 cells treated with the lipopolysaccharide and the compounds.Then,the target compounds were studied for their activity in dextran sodium sulfate(DSS)-induced ulcerative colitis.Results A total of three series of compounds encompassing 60 derivatives of the natural product butyrolactone V were designed and synthesized.The results showed that compounds 5p and 7e could alleviate the symptoms of DSS-induced colitis in mice,including alleviating diarrhea,inhibiting the reduction of colon length,and reducing tissue damage.The preliminary mechanism exploration indicated that compounds 5p and 7e could improve the symptoms of IBD in mice mainly by reducing the expression of chemokines and exerting anti-inflammatory effects.Conclusion This study reports the synthesis and the derivatization of butyrolactone V and analysis on anti-inflammatory activity.The most effective compounds 5p and 7e have the potential to be further developed as drugs to treat IBD.
基金supported in part by the China Huaneng Group Co.,Ltd.project“Research on the Optimization of Mid-long Term Electric Power Structure Transition of China Huaneng Group”(No.HNKJ20-H01)。
文摘Nuclear power development is a complex issue spanning cyber,physical,and social systems that is essential to achieving energy security and climate goals.With the ongoing worldwide trend towards carbon neutrality,the positioning of nuclear power in energy mix should be reconsidered.This paper aims to present a systematic review of current research on optimization of nuclear power development.The concept of cyber-physical-social system in energy(CPSSE)is adopted,which provides a suitable perspective and enables the review of relevant studies to achieve some novel insights.Based on the CPSSE,firstly,a research framework is established and the main research elements in optimization are identified,followed by a proposed conceptual risk-based optimization model.Secondly,current studies are analyzed and classified into four categories according to the research boundary.The status quo and limitations are discussed.It is found that the research results of nuclear-specific issues have not been well integrated into the optimization of nuclear power.As a relatively reliable power supply,nuclear power is capable of maintaining power and electricity adequacy of the whole system,especially in the case of power shortage caused by long-period low output of renewable energy or extreme external disasters.This superiority should not be ignored in the optimization.Other critical factors that should be further considered include disruptive technologies,nuclear safety,energy policies,and stakeholder behaviors.Finally,suggestions are given for future research.
基金supported by grants from the National Natural Science Foundation of China(32320103003 and 32122070)the“High-end Foreign Experts Recruitment Plan”of Ministry of Science and Technology(G2023108007L)+3 种基金Chinese Universities Scientific Fund(2023TC074)Pinduoduo-China Agricultural University Research Fund(PC2023B02012)China National Postdoctoral Program for Innovative Talents(BX20240421)2115 Talent Development Program of China Agricultural University.
文摘Suppressor of G2 allele of skp1(SGT1)is a highly conserved eukaryotic protein that plays a vital role in growth,development,and immunity in both animals and plants.Although some SGT1 interactors have been identified,the molecular regulatory network of SGT1 remains unclear.SGT1 serves as a co-chaperone to stabilize protein complexes such as the nucleotide-binding leucine-rich repeat(NLR)class of immune receptors,thereby positively regulating plant immunity.SGT1 has also been found to be asso-ciated with the SKP1-Cullin-F-box(SCF)E3 ubiquitin ligase complex.However,whether SGT1 targets im-mune repressors to coordinate plant immune activation remains elusive.In this study,we constructed a toolbox for TurbolD-and split-TurbolD-based proximity labeling(PL)assays in Nicotiana benthamiana and used the PL toolbox to explore the SGT1 interactome during pre-and post-immune activation.The comprehensive SGT1 interactome network we identified highlights a dynamic shift from proteins associ-ated with plant development to those linked with plant immune responses.We found that SGT1 interacts with Necrotic Spotted Lesion1(NSL1),which negatively regulates salicylic acid-mediated defenseby inter-fering with the nucleocytoplasmic trafficking of non-expressor of pathogenesis-related genes 1(NPR1)during N NLR-mediated response to tobacco mosaic virus.SGT1 promotes the SCF-dependent degrada-tion of NSL1 to facilitate immune activation,while salicylate-induced protein kinase-mediated phosphory-lation of SGT1further potentiates this process.Besides NNLR,NSL1also functions in several other NLR-mediated immunity.Collectively,our study unveils the regulatory landscape of SGT1 and reveals a novel SGT1-NSL1 signaling module that orchestrates plant innate immunity.
基金supported by the National Key Research and Development Program of China (2018YFA0702100)the National Natural Science Foundation of China (21771123)+2 种基金the Programme of Introducing Talents of Discipline to Universities (D16002)the Science and Technology Commission of Shanghai Municipality (15DZ2260300)Key Laboratory of Optoelectronic Materials Chemistry and Physics, Chinese Academy of Sciences (2008DP173016)
文摘Antimony-based Zintl compounds AM2Sb2(A=Ca,Sr,Ba,Yb,Eu;M=Mg,Zn,Cd,Mn),which enable a broad range of manipulation on electrical and thermal transport properties,are considered as an important class of thermoelectric materials.Phonon and carrier transport engineering were realized in YbMg2Sb2 via equivalent and aliovalent substitution of Zn and Ag,respectively.The roomtemperature thermal conductivity reduces from 1.96 to 1.15 W m^-1 K^-1 for YbMg2-xZnxSb2 due to the mass and strain fluctuation through the formation of the absolute solid solution of YbMg2Sb2-YbZn2Sb2.Furthermore,the carrier concentration has been further optimized by Ag doping(from 0.42×10^19 to 7.72×10^19 cm^-3 at room temperature),and thus the electrical conductivity and the power factor are enhanced effectively.The integrated aspects make the dimensionless figure of merit(zT)reach 0.48 at 703 K,which is 60%higher than the pristine YbMgZnSb2 sample.
