Flexible zinc-ion batteries(FZIBs)have been acknowledged as a potential cornerstone for the future development of flexible energy storage,yet conventional FZIBs still encounter challenges,particularly concerning perfo...Flexible zinc-ion batteries(FZIBs)have been acknowledged as a potential cornerstone for the future development of flexible energy storage,yet conventional FZIBs still encounter challenges,particularly concerning performance failure at low temperatures.To address these challenges,a novel anti-freezing leather gel electrolyte(AFLGE-30)is designed,incorporating ethanol as a hydrogen bonding acceptor.The AFLGE-30 demonstrates exceptional frost resistance while maintaining favorable flexibility even at-30℃;accordingly,the battery can achieve a high specific capacity of about 70 m Ah/g.Cu//Zn battery exhibits remarkable stability at room temperature,retaining~96%efficiency after 120 plating/stripping cycles at1 m A/cm^(2).Concurrently,the Zn//Zn symmetric batteries demonstrate a lifespan of 4100 h at room temperature,which is attributed to the enhancement of Zn^(2+)deposition kinetics,restraining the formation of zinc dendrites.Furthermore,FZIBs exhibit minimal capacity loss even after bending,impacting,or burning.This work provides a promising strategy for designing low-temperature-resistant FZIBs.展开更多
Organic electrodes are considered competitive candidates for the next-generation high-performance energy storage devices owing to their advantages of structural flexibility and abundant resources.However,solubility an...Organic electrodes are considered competitive candidates for the next-generation high-performance energy storage devices owing to their advantages of structural flexibility and abundant resources.However,solubility and low electronic conductivity have been major obstacles to the practical application.To address these challenges,the structural design and interfacial regulation of organic electrodes are crucial to the performance enhancement.Herein,we report on aπ-conjugated polymer cathode material of poly(3,4,9,10-perylenetetracarboxylic diimide)(PPI)for metal ion batteries,and the performance optimization is achieved by matching suitable conductive carbons and liquid electrolytes.Ultimately,the carbon nanotubes(CNTs)with weight content of 25%and 1 M NaPF6 in ethylene carbonate/diethyl carbonate electrolyte are introduced to assemble the batteries,and the discharge specific capacity,cycling stability and rate performance are enhanced effectively.The PPI-CNTjjNa battery displays high specific capacities of 146.4 and 117 mAh g^(-1) at current densities of 0.1 C and 5 C,respectively.Furthermore,PPI-CNTjjNa battery demonstrates excellent long-term cycling stability of 5000 cycles with low 0.007 mAh g^(-1)capacity decay per cycle at 1C due to the thin and uniform cathode electrolyte interphase.Moreover,the PPI-CNTjjNa battery presents good cycling stability at high temperatures of 60℃,and retains a capacity of 132.5 mAh g^(-1) after 300 cycles with a high capacity retention rate of 96.9%.Besides,PPI-CNT displays good electrochemical performance and compatibility in lithium-ion and potassium-ion batteries.This work provides an alternative optimization strategy for organic electrodes applied in long-lifetime metal ion batteries.展开更多
The color difference of capsicum fruit is closely related to the type and content of pigment in the peel,which is mainly determined by anthocyanins,chlorophyll,and carotenoids.This study used green“CA59”and purple“...The color difference of capsicum fruit is closely related to the type and content of pigment in the peel,which is mainly determined by anthocyanins,chlorophyll,and carotenoids.This study used green“CA59”and purple“Z81”pepper fruits as parents to create the F2 generation.The fruit color of 466 F2 population was identified,and the extreme individuals from this population were selected for Bulked Segregant Analysis(BSA)using resequencing.Genetic analysis revealed that a pair of genes controls the expression of the purple fruit trait in capsicum.Using functional annotation,expression analysis,and sequencing analysis of candidate genes,it was determined that there were four genes in the region between InDel 67 and InDel 75(185,664,068 BP-186,514,350 bp)on chromosome 10,that is the linkage interval for pepper purple fruit.There are 7 SNPs in the CaMYB1 gene(Capann_59V1aChr10g016200)in the pepper variety“Z81”.Of these,4 SNPs are located in the gene’s coding region.These 4 SNPs lead to 2 mutations that do not change the amino acid sequence(synonymous mutations)and 2 mutations that do change the amino acid sequence(non-synonymous mutations).Additionally,the expression level of the CaMYB1 gene in the purple fruit of“Z81”is significantly higher than that in the green fruit of“CA59”.CaMYB1 is believed to be a crucial candidate gene in regulating anthocyanin production in purple capsicum fruit.A molecular marker,InDel 67,was successfully developed,with a total separation rate of 92.4%.展开更多
The skin wound is susceptible to bacterial invasion,which hinders the healing of the wound,especially when infected with multi-drug resistant strains.This demands novel bioactive materials to combat bacterial infectio...The skin wound is susceptible to bacterial invasion,which hinders the healing of the wound,especially when infected with multi-drug resistant strains.This demands novel bioactive materials to combat bacterial infections.In this study,gallium oxide nanoparticles(Ga_(2)O_(3)NPs)were successfully synthesized through high-temperature thermal decomposition,exhibiting excellent biocompatibility and photocatalytic antimicrobial activity.The Ga_(2)O_(3)NPs were crosslinked into chitosan hydrogel to create a light-responsive multilayered 3D porous hydrogel(Ga_(2)O_(3)NPs hydrogel)for use in photocatalytic antimicrobial therapy(PCAT).The prepared Ga_(2)O_(3)NPs hydrogel exhibits broad-spectrum photocatalytic activity and remarkable antibacterial efficacy against E.coli and S.aureus.It effectively eradicates biofilms,promotes reactive oxygen species production,disrupts bacterial cell membranes,and induces nucleic acid leakage,ultimately resulting in bacterial death.Additionally,it exhibits excellent biosafety.Both in vitro pigskin and in vivo mouse wound infection models have confirmed the remarkable efficacy of Ga_(2)O_(3)NPs hydrogel in PCAT.Notably,Ga_(2)O_(3)NPs hydrogel created a moist environment for the wound in an MDR S.aureus-infected mouse wound model,demonstrating significant potential to facilitate wound healing and minimize scar formation.This study introduces a novel hydrogel dressing without antibiotic components for resistant bacterial-infected wounds.展开更多
In the broader field of mechanical technology,and particularly in the context of self-driving vehicles,cameras and Light Detection and Ranging(LiDAR)sensors provide complementary modalities that hold significant poten...In the broader field of mechanical technology,and particularly in the context of self-driving vehicles,cameras and Light Detection and Ranging(LiDAR)sensors provide complementary modalities that hold significant potential for sensor fusion.However,directly merging multi-sensor data through point projection often results in information loss due to quantization,and managing the differing data formats from multiple sensors remains a persistent challenge.To address these issues,we propose a new fusion method that leverages continuous convolution,point-pooling,and a learned Multilayer Perceptron(MLP)to achieve superior detection performance.Our approach integrates the segmentation mask with raw LiDAR points rather than relying on projected points,effectively avoiding quantization loss.Additionally,when retrieving corresponding semantic information from images through point cloud projection,we employ linear interpolation and upsample the image feature maps to mitigate quantization loss.We employ nearest-neighbor search and continuous convolution to seamlessly fuse data from different formats.Moreover,we integrate pooling and aggregation operations,which serve as conceptual extensions of convolution,and are specifically designed to reconcile the inherent disparities among these data representations.Our detection network operates in two stages:in the first stage,preliminary proposals and segmentation features are generated;in the second stage,we refine the fusion results together with the segmentation mask to yield the final prediction.Notably,in our approach,the image network is used solely to provide semantic information,serving to enhance the point cloud features.Extensive experiments on the Karlsruhe Institute of Technology and Toyota Technological Institute(KITTI)dataset demonstrate the effectiveness of our approach,which achieves both high precision and robust performance in 3D object detection tasks.展开更多
Plant architecture traits influence crop yield. An understanding of the genetic basis of cotton plant architecture traits is beneficial for identifying favorable alleles and functional genes and breeding elite cultiva...Plant architecture traits influence crop yield. An understanding of the genetic basis of cotton plant architecture traits is beneficial for identifying favorable alleles and functional genes and breeding elite cultivars. We collected 121 cotton accessions including 100 brownfiber and 21 white-fiber accessions, genotyped them by whole-genome resequencing, and phenotyped them in multiple environments. This genome-wide association study(GWAS)identified 11 quantitative trait loci(QTL) for two plant architecture traits: plant height and fruit spur branch number. Negative-effect alleles were enriched in the elite cultivars. Based on these QTL, gene annotation information, and published QTL, candidate genes and natural genetic variations in four QTL were identified. Ghir_D02 G017510 and Ghir_D02 G017600 were identified as candidate genes for qD02-FSBN-1, and a premature start codon gain variation was found in Ghir_D02 G017510. Ghir_A12 G026570, the candidate gene of qA12-FSBN-2, belongs to the pectin lyase-like superfamily, and a significantly associated SNP, A12_105366045(T/C), in this gene represents an amino acid change. The QTL, candidate genes, and associated natural variations in this study are expected to lay a foundation for studying functional genes and developing breeding programs for desirable architecture in brown-fiber cotton.展开更多
Near-infrared(NIR)light-triggered photothermal therapy(PTT)is a promising treatment strategy for treating cancer.The combination of nanotechnology and NIR has been widely applied.However,the therapeutic efficacy of th...Near-infrared(NIR)light-triggered photothermal therapy(PTT)is a promising treatment strategy for treating cancer.The combination of nanotechnology and NIR has been widely applied.However,the therapeutic efficacy of the drug-delivery system depends on their ability to avoid phagocytosis of endothelial system,cross the biological barriers,prolong circulation life,localize and rapidly release the therapeutic at target sites.In this work,we designed a platelet membrane(PM)-camouflaged hollow mesoporous bismuth selenide nanoparticles(BS NPs)loading with indocyanine green(ICG)(PM@BS-ICG NPs)to achieve the above advantages.PM-coating has active tumor-targe ting ability which could preve nt drug leakage and provide drug long circulation,causing drug delivery systems to accumulate in tumor sites effectively.Moreover,as a type of the photothermal sensitizers,BS NPs are used as the inner cores to improve ICG stability and are served as scaffolds to enhance the hardness of this drug delivery system.For one hand,the thermal vibration of BS NPs under NIR laser irradiation causes tumor inhibition through hyperthermia.For another hand,this hyperthermia process could damage PM and let ICG rapid release from PM@BS-ICG NPs.The in vitro and in vivo results showed that this biomimetic nano-drug delivery system exhibits obvious antitumor activity which has good application prospect.展开更多
The morphological evolution and coarsening kinetics ofγ'precipitates in a Re-containing Ni-based single crystal superalloy were investigated during isothermal aging at 900,950 and 1000℃.After heat treatment,well...The morphological evolution and coarsening kinetics ofγ'precipitates in a Re-containing Ni-based single crystal superalloy were investigated during isothermal aging at 900,950 and 1000℃.After heat treatment,well-defined cuboidalγ'precipitates with low misfit was obtained within the experimental alloy.Then coarsening rate constants and particle size distribution(PSD)ofγ'phases were calculated and specified based on the measured precipitate sizes for va rying periods of aging times from 100 to 2000 h.After aging for 2000 h,γ'precipitates maintained cubical shape at 900℃,while exhibited sphere at 950 and 1000℃.Coarsening models based on diffusion-controlled process with a functional relationship of r^(3) vs.t(classic Lifshitz-Slyozov-Wagner coarsening model)and interface-controlled model with a function of r^(2) vs.t(trans-interface diffusion-controlled coarsening model)were investigated to fit between the experimental results and theoretical analysis.It was found that Re as the slowest diffusing solute in the alloy constituted the rate-limited step for coarsening based on LSW model,while the process limiting coarsening as governed by an interface diffusion process could possibly be related to the Al diffusion through theγ/γ'interface.The PSDs and coarsening exponent were discussed by comparing the experimental data with predictions of LSW and TIDC models.Finally,coarsening mechanism could be divided into four regimes:(i)coarsening by diffusion-controlled;(ii)coarsening by diffusion and interface cocontrolled;(iii)coarsening by interface-controlled;(iv)coarsening by interface-controlled accompanied withγ'coalescence.展开更多
Cellulase is a complex enzyme that can decompose cellulose into glucose,and it could effectively treat cellulose waste. In this paper,it aims to explore development status and research progress of cellulase,and introd...Cellulase is a complex enzyme that can decompose cellulose into glucose,and it could effectively treat cellulose waste. In this paper,it aims to explore development status and research progress of cellulase,and introduce concept and action mechanism of cellulase,research situation of cellulase in molecular aspect,application of cellulase,and development of cellulase is also prospected.展开更多
Photothermal therapy(PTT)-induced immune response has attracted much attention,however,which cannot work at full capacity.In this study,the simvastatin(SV)adjuvant is loaded into gold nanocages(AuNCs)to develop a simp...Photothermal therapy(PTT)-induced immune response has attracted much attention,however,which cannot work at full capacity.In this study,the simvastatin(SV)adjuvant is loaded into gold nanocages(AuNCs)to develop a simple drug delivery system,which can efficiently utilize the tumor-associated antigens(TAAs)for improving immune responses.AuNCs/SV-mediated PTT treatment enhances tumor cells damage and promotes the release of TAAs which are immediately captured by Au NCs/SV to form AuNCs/SV/TAAs recombinant nanoparticle.Impressively,AuNCs/SV/TAAs can accumulate in lymph nodes effectively due to the suitable size of~55 nm and hyperthermia-induced vasodilative effect.And the codelivery of antigen and adjuvant is beneficial to stimulating the maturation of dendritic cells for further activating T cells.In a word,the recombinant strategy could make full use of TAAs to produce an individual powerful immunotherapy.展开更多
Sodium-ion battery is a potential application system for large-scale energy storage due to the advantage of higher nature abundance and lower production cost of sodium-based materials.However,there exist inevitably th...Sodium-ion battery is a potential application system for large-scale energy storage due to the advantage of higher nature abundance and lower production cost of sodium-based materials.However,there exist inevitably the safety problems such as flammability due to the use of the same type of organic liquid electrolyte with lithium-ion battery.Gel polymer electrolytes are being considered as an effective solution to replace conventional organic liquid electrolytes for building safer sodium-ion batteries.In this review paper,the authors present a comprehensive overview of the research progress in electrochemical and physical properties of the gel polymer electrolyte-based sodium batteries.The gel polymer electrolytes based on different polymer hosts namely poly(ethylene oxide),poly(acrylonitrile),poly(methyl methacrylate),poly(vinylidene fluoride),poly(vinylidene fluoride-hexafluoro propylene),and other new polymer networks are summarized.The ionic conductivity,ion transference number,electrochemical window,thermal stability,mechanical property,and interfacial issue with electrodes of gel polymer electrolytes,and the corresponding influence factors are described in detail.Furthermore,the ion transport pathway and ion conduction mechanism are analyzed and discussed.In addition,the advanced gel polymer electrolyte systems including flame-retardant polymer electrolytes,composite gel polymer electrolytes,copolymerization,single-ion conducting polymer electrolytes,etc.with more superior and functional performance are classified and summarized.Finally,the application prospects,development opportunities,remaining challenges,and possible solutions are discussed.展开更多
Carbon materials derived from biomass waste are considered as potential electrocatalysts for applications in zinc-air batteries(ZABs)due to their low cost and good catalytic activity.Here,we reported the preparation o...Carbon materials derived from biomass waste are considered as potential electrocatalysts for applications in zinc-air batteries(ZABs)due to their low cost and good catalytic activity.Here,we reported the preparation of gel-based catalysts through utilizing hydrolyzed waste leather powder cross-linked with metallic salt solutions.After calcination,iron-nickel alloy anchored in nitrogen-doped porous carbon catalysts(Fe Ni@NDC)was achieved.Compared with commercial Pt/C catalyst,Fe Ni@NDC-800 exhibited lower E_(1/2)(0.77 V)and better durability.More importantly,the resulting Fe Ni@NDC-800-based alkaline ZABs achieved power density of 93.01 m W/cm^(2) and open circuit voltage of 1.45 V,which the Fe Ni@NDC-800-based neutral ZAB displayed a charge/discharge cycle stability of 275 h.This work opens up the possibility of rational design and preparation of low-cost and high-performance electrocatalysts from recyclable leather waste.展开更多
In device-to-device(D2D)underlay cellular networks with downlink spectrum sharing,massive MIMO seems promising as the large number of antennas at the base station(BS) can be utilized to suppress interference.However,t...In device-to-device(D2D)underlay cellular networks with downlink spectrum sharing,massive MIMO seems promising as the large number of antennas at the base station(BS) can be utilized to suppress interference.However,the channel state information(CSI) from the BS to D2D receivers is required to obtain this advantage.In this paper,we first propose a novel time division duplex(TDD) scheme for D2D users to acquire this CSI,without additional pilot overhead.Moreover,we propose an interference-aware MMSE precoder utilizing the acquired CSI from the BS to not only cellular users but also D2D users to suppress the cellular-to-D2D interference.Simulation results show that our proposed TDD scheme and precoder can significantly improve the achievable sum spectral efficiency(SE) and D2D SE,compared to the classical MMSE precoder.Compared with the interferenceaware ZF precoder,whose performance severely degrades for large user numbers,our proposed interference-aware MMSE precoder can always guarantees a high and stable performance in terms of achievable SE.展开更多
Globally,fossil fuel dependence has created several environmental challenges and climate change.Hence,creating other alternative renewable and ecologically friendly bio-energy sources is necessary.Lignocellulosic biom...Globally,fossil fuel dependence has created several environmental challenges and climate change.Hence,creating other alternative renewable and ecologically friendly bio-energy sources is necessary.Lignocellulosic biomass has gained significant attention recently as a renewable material for biofuel production.The large amounts of plantain and banana plant parts wasted after harvesting,as well as the peels generated daily by the fruit market and industries,demonstrate the potential of bioenergy resources.This review briefly assesses plantain and banana plant biomass(PBB)generated in the developing,developed,and underdeveloped countries,the consumable parts,and feasible products yield.It emphasized the advantages and disadvantages of the commonly adopted treatment technologies of composting,incineration,and landfilling.Further,the utilization of PBB as catalysts in biodiesel synthesis was briefly highlighted.To optimize recovery of biofuel,different integration routes of pyrolysis,anaerobic digestion,fermentation,hydrothermal carbonization,hydrothermal liquefaction,and hydrothermal gasification for the valorization of the PBB were proposed.The complex compounds present in the PBB(hemicellulose,cellulose,and lignin)can be converted into valuable bio-products such as methane gas and bio-ethanol for bioenergy,and nutrients to promote bioactive ingredients.The investigation of the viability and innovation potential of the integrated routes’technology is necessary to improve the circular bio-economy and the recovery of biofuels from biomass waste,particularly PBB.展开更多
Inhaled drug-containing nanocarriers have been well applied as an important strategy in pulmonary dis-eases.Acute lung injury(ALI)is characterized by abnormal lung tension and complex pathogenesis,with high mortality ...Inhaled drug-containing nanocarriers have been well applied as an important strategy in pulmonary dis-eases.Acute lung injury(ALI)is characterized by abnormal lung tension and complex pathogenesis,with high mortality because of the limitations of targeted intervention.Accordingly,in the present study,we first identified that the mechanosensitive ion channel Piezo1 participated in the ALI-associated processes induced by lipopolysaccharide(LPS)in vitro and in vivo.Then,chitosan-stabilized bovine serum albu-min nanoparticles(NCs)emulsified with the Piezo1 inhibitor GsMTx4(NC-GsMTx4)were generated and exhibited excellent biocompatibility and biological function.Through aerosol inhalation,NC-GsMTx4 im-proved lung injury and inhibited cell apoptosis in LPS-stressed ALI mice and alleviated pulmonary fibrosis during the later stage of ALI.Mechanistically,GsMTx4 could regulate inflammation and apoptosis in lung epithelial cells via NF-κB and ERK1/2 signaling.In summary,our findings provide new insights into the pathological mechanisms of Piezo1 in ALI progression,and nebulized inhalation of NC-GsMTx4 offers a prospective platform for targeting Piezo1 to treat ALI efficiently and conveniently.展开更多
Bacterial-based antitumor immunity has become a promising strategy to activate the immune system for fighting cancer.However,the potential application of bacterial therapy is hindered by the presence of instability an...Bacterial-based antitumor immunity has become a promising strategy to activate the immune system for fighting cancer.However,the potential application of bacterial therapy is hindered by the presence of instability and susceptibility to infections within bacterial populations.Furthermore,monotherapy is ineffective in completely eliminating complex cancer with multiple contributing factors.In this study,based on our discovery that spore shell(SS)of Bacillus coagulans exhibits excellent tumor-targeting ability and adjuvant activity,we develop a biomimetic spore nanoplatform to boost bacteria-mediated antitumor therapy,chemodynamic therapy and antitumor immunity for synergistic cancer treatment.In detail,SS is separated from probiotic spores and then attached to the surface of liposome(Lipo)that was loaded with hemoglobin(Hb),glucose oxidase(GOx)and JQ1to construct SS@Lipo/Hb/GOx/JQ1.In tumor tissue,highly toxic hydroxyl radicals(·OH)are generated via sequential catalytic reactions:GOx catalyzing glucose into H_(2)O_(2)and Fe^(2+)in Hb decomposing H_(2)O_(2)into·OH.The combination of·OH and SS adjuvant can improve tumor immunogenicity and activate immune system.Meanwhile,JQ1-mediated down-regulation of PD-L1 and Hb-induced hypoxia alleviation synergistically reshape immunosuppressive tumor microenvironment and potentiate immune response.In this manner,SS@Lipo/Hb/GOx/JQ1 significantly suppresses tumor growth and metastasis.To summarize,the nanoplatform represents an optimum strategy to potentiate bacteria-based cancer immunotherapy.展开更多
The Internet now is a large-scale platform with big data. Finding truth from a huge dataset has attracted extensive attention, which can maintain the quality of data collected by users and provide users with accurate ...The Internet now is a large-scale platform with big data. Finding truth from a huge dataset has attracted extensive attention, which can maintain the quality of data collected by users and provide users with accurate and efficient data. However, current truth finder algorithms are unsatisfying, because of their low accuracy and complication. This paper proposes a truth finder algorithm based on entity attributes (TFAEA). Based on the iterative computation of source reliability and fact accuracy, TFAEA considers the interactive degree among facts and the degree of dependence among sources, to simplify the typical truth finder algorithms. In order to improve the accuracy of them, TFAEA combines the one-way text similarity and the factual conflict to calculate the mutual support degree among facts. Furthermore, TFAEA utilizes the symmetric saturation of data sources to calculate the degree of dependence among sources. The experimental results show that TFAEA is not only more stable, but also more accurate than the typical truth finder algorithms.展开更多
In this paper, the effects of annealing time on the dielectric properties of the Spark Plasma Sintered (SPS) BaMn3Ti4O14.25 pellets were detail studied by the crystal structure analysis, micro structural observation a...In this paper, the effects of annealing time on the dielectric properties of the Spark Plasma Sintered (SPS) BaMn3Ti4O14.25 pellets were detail studied by the crystal structure analysis, micro structural observation and electrical properties research. The results showed that long annealing time was beneficial to the recovery of crystal structure damage caused by SPS, the formation of a reoxidation layer at the surface of grains and decreasing of the electrically insulating phase. All of these resulted in an increase in dielectric constant and loss, and a reduction in breakdown voltage.展开更多
Forward modeling of elastic wave propagation in porous media has great importance for understanding and interpreting the influences of rock properties on characteristics of seismic wavefield. However,the finite-differ...Forward modeling of elastic wave propagation in porous media has great importance for understanding and interpreting the influences of rock properties on characteristics of seismic wavefield. However,the finite-difference forward-modeling method is usually implemented with global spatial grid-size and time-step; it consumes large amounts of computational cost when small-scaled oil/gas-bearing structures or large velocity-contrast exist underground. To overcome this handicap,combined with variable grid-size and time-step,this paper developed a staggered-grid finite-difference scheme for elastic wave modeling in porous media. Variable finite-difference coefficients and wavefield interpolation were used to realize the transition of wave propagation between regions of different grid-size. The accuracy and efficiency of the algorithm were shown by numerical examples. The proposed method is advanced with low computational cost in elastic wave simulation for heterogeneous oil/gas reservoirs.展开更多
基金supported by the National Natural Science Foundation of China(Nos.22075139 and 62288102)。
文摘Flexible zinc-ion batteries(FZIBs)have been acknowledged as a potential cornerstone for the future development of flexible energy storage,yet conventional FZIBs still encounter challenges,particularly concerning performance failure at low temperatures.To address these challenges,a novel anti-freezing leather gel electrolyte(AFLGE-30)is designed,incorporating ethanol as a hydrogen bonding acceptor.The AFLGE-30 demonstrates exceptional frost resistance while maintaining favorable flexibility even at-30℃;accordingly,the battery can achieve a high specific capacity of about 70 m Ah/g.Cu//Zn battery exhibits remarkable stability at room temperature,retaining~96%efficiency after 120 plating/stripping cycles at1 m A/cm^(2).Concurrently,the Zn//Zn symmetric batteries demonstrate a lifespan of 4100 h at room temperature,which is attributed to the enhancement of Zn^(2+)deposition kinetics,restraining the formation of zinc dendrites.Furthermore,FZIBs exhibit minimal capacity loss even after bending,impacting,or burning.This work provides a promising strategy for designing low-temperature-resistant FZIBs.
基金supported by Open Foundation of Shanghai Jiao Tong University Shaoxing Research Institute of Renewable Energy and Molecular Engineering(Grant No.JDSX2023008)Joint Fund of Scientific and Technological Research and Development Program of Henan Province(222301420009)the funding of Zhengzhou University.
文摘Organic electrodes are considered competitive candidates for the next-generation high-performance energy storage devices owing to their advantages of structural flexibility and abundant resources.However,solubility and low electronic conductivity have been major obstacles to the practical application.To address these challenges,the structural design and interfacial regulation of organic electrodes are crucial to the performance enhancement.Herein,we report on aπ-conjugated polymer cathode material of poly(3,4,9,10-perylenetetracarboxylic diimide)(PPI)for metal ion batteries,and the performance optimization is achieved by matching suitable conductive carbons and liquid electrolytes.Ultimately,the carbon nanotubes(CNTs)with weight content of 25%and 1 M NaPF6 in ethylene carbonate/diethyl carbonate electrolyte are introduced to assemble the batteries,and the discharge specific capacity,cycling stability and rate performance are enhanced effectively.The PPI-CNTjjNa battery displays high specific capacities of 146.4 and 117 mAh g^(-1) at current densities of 0.1 C and 5 C,respectively.Furthermore,PPI-CNTjjNa battery demonstrates excellent long-term cycling stability of 5000 cycles with low 0.007 mAh g^(-1)capacity decay per cycle at 1C due to the thin and uniform cathode electrolyte interphase.Moreover,the PPI-CNTjjNa battery presents good cycling stability at high temperatures of 60℃,and retains a capacity of 132.5 mAh g^(-1) after 300 cycles with a high capacity retention rate of 96.9%.Besides,PPI-CNT displays good electrochemical performance and compatibility in lithium-ion and potassium-ion batteries.This work provides an alternative optimization strategy for organic electrodes applied in long-lifetime metal ion batteries.
基金supported by the National Natural Science Foundation of China(U2IA20230)the Guangdong Modern Vegetable Industry Technology System Project(2024CXTD08)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(2024A1515010403)the Xizang Autonomous Region of Lhasa City Science and Technology Project(LSKJ202418)the Guangdong Provincial Department of Agriculture and Rural Affairs(Selection and Breeding of New High-Yielding and High-Quality Pepper Varieties)(2024-NPY-00-020).
文摘The color difference of capsicum fruit is closely related to the type and content of pigment in the peel,which is mainly determined by anthocyanins,chlorophyll,and carotenoids.This study used green“CA59”and purple“Z81”pepper fruits as parents to create the F2 generation.The fruit color of 466 F2 population was identified,and the extreme individuals from this population were selected for Bulked Segregant Analysis(BSA)using resequencing.Genetic analysis revealed that a pair of genes controls the expression of the purple fruit trait in capsicum.Using functional annotation,expression analysis,and sequencing analysis of candidate genes,it was determined that there were four genes in the region between InDel 67 and InDel 75(185,664,068 BP-186,514,350 bp)on chromosome 10,that is the linkage interval for pepper purple fruit.There are 7 SNPs in the CaMYB1 gene(Capann_59V1aChr10g016200)in the pepper variety“Z81”.Of these,4 SNPs are located in the gene’s coding region.These 4 SNPs lead to 2 mutations that do not change the amino acid sequence(synonymous mutations)and 2 mutations that do change the amino acid sequence(non-synonymous mutations).Additionally,the expression level of the CaMYB1 gene in the purple fruit of“Z81”is significantly higher than that in the green fruit of“CA59”.CaMYB1 is believed to be a crucial candidate gene in regulating anthocyanin production in purple capsicum fruit.A molecular marker,InDel 67,was successfully developed,with a total separation rate of 92.4%.
基金financially supported by the Advanced Fiber Materials Engineering Research Center of Anhui Province(No.2023AFMC20)the Scientific Research Foundation for Advanced Talents of Anhui Polytechnic University(No.2022YQQ072)+5 种基金the Anhui Province Key Research and Development Program(No.2022i01020002)the Key Project Foundation of Anhui Higher Education Institutes of China(No.2023AH050941)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.22KJB180020)the Transversal Project(No.KH10004443),the Anhui Provincial Natural Science Foundation(No.2308085Y45)the Program for Excellent Sci-tech Innovation Teams of Universities in Anhui Province(No.2023AH010073)Wuhu Science and Technology Department project(No.2023jc22).
文摘The skin wound is susceptible to bacterial invasion,which hinders the healing of the wound,especially when infected with multi-drug resistant strains.This demands novel bioactive materials to combat bacterial infections.In this study,gallium oxide nanoparticles(Ga_(2)O_(3)NPs)were successfully synthesized through high-temperature thermal decomposition,exhibiting excellent biocompatibility and photocatalytic antimicrobial activity.The Ga_(2)O_(3)NPs were crosslinked into chitosan hydrogel to create a light-responsive multilayered 3D porous hydrogel(Ga_(2)O_(3)NPs hydrogel)for use in photocatalytic antimicrobial therapy(PCAT).The prepared Ga_(2)O_(3)NPs hydrogel exhibits broad-spectrum photocatalytic activity and remarkable antibacterial efficacy against E.coli and S.aureus.It effectively eradicates biofilms,promotes reactive oxygen species production,disrupts bacterial cell membranes,and induces nucleic acid leakage,ultimately resulting in bacterial death.Additionally,it exhibits excellent biosafety.Both in vitro pigskin and in vivo mouse wound infection models have confirmed the remarkable efficacy of Ga_(2)O_(3)NPs hydrogel in PCAT.Notably,Ga_(2)O_(3)NPs hydrogel created a moist environment for the wound in an MDR S.aureus-infected mouse wound model,demonstrating significant potential to facilitate wound healing and minimize scar formation.This study introduces a novel hydrogel dressing without antibiotic components for resistant bacterial-infected wounds.
文摘In the broader field of mechanical technology,and particularly in the context of self-driving vehicles,cameras and Light Detection and Ranging(LiDAR)sensors provide complementary modalities that hold significant potential for sensor fusion.However,directly merging multi-sensor data through point projection often results in information loss due to quantization,and managing the differing data formats from multiple sensors remains a persistent challenge.To address these issues,we propose a new fusion method that leverages continuous convolution,point-pooling,and a learned Multilayer Perceptron(MLP)to achieve superior detection performance.Our approach integrates the segmentation mask with raw LiDAR points rather than relying on projected points,effectively avoiding quantization loss.Additionally,when retrieving corresponding semantic information from images through point cloud projection,we employ linear interpolation and upsample the image feature maps to mitigate quantization loss.We employ nearest-neighbor search and continuous convolution to seamlessly fuse data from different formats.Moreover,we integrate pooling and aggregation operations,which serve as conceptual extensions of convolution,and are specifically designed to reconcile the inherent disparities among these data representations.Our detection network operates in two stages:in the first stage,preliminary proposals and segmentation features are generated;in the second stage,we refine the fusion results together with the segmentation mask to yield the final prediction.Notably,in our approach,the image network is used solely to provide semantic information,serving to enhance the point cloud features.Extensive experiments on the Karlsruhe Institute of Technology and Toyota Technological Institute(KITTI)dataset demonstrate the effectiveness of our approach,which achieves both high precision and robust performance in 3D object detection tasks.
基金supported by the Fundamental Research Funds for the Central Universities(2662015PY097)the Breeding of New Early Maturing and High-quality Coloured Cotton Varieties(2016HZ09)
文摘Plant architecture traits influence crop yield. An understanding of the genetic basis of cotton plant architecture traits is beneficial for identifying favorable alleles and functional genes and breeding elite cultivars. We collected 121 cotton accessions including 100 brownfiber and 21 white-fiber accessions, genotyped them by whole-genome resequencing, and phenotyped them in multiple environments. This genome-wide association study(GWAS)identified 11 quantitative trait loci(QTL) for two plant architecture traits: plant height and fruit spur branch number. Negative-effect alleles were enriched in the elite cultivars. Based on these QTL, gene annotation information, and published QTL, candidate genes and natural genetic variations in four QTL were identified. Ghir_D02 G017510 and Ghir_D02 G017600 were identified as candidate genes for qD02-FSBN-1, and a premature start codon gain variation was found in Ghir_D02 G017510. Ghir_A12 G026570, the candidate gene of qA12-FSBN-2, belongs to the pectin lyase-like superfamily, and a significantly associated SNP, A12_105366045(T/C), in this gene represents an amino acid change. The QTL, candidate genes, and associated natural variations in this study are expected to lay a foundation for studying functional genes and developing breeding programs for desirable architecture in brown-fiber cotton.
基金supported by the National Natural Science Foundation of China(Nos.81673021 and U1804183)the Scientific and Technological Project of Henan Province(No.182102310117)。
文摘Near-infrared(NIR)light-triggered photothermal therapy(PTT)is a promising treatment strategy for treating cancer.The combination of nanotechnology and NIR has been widely applied.However,the therapeutic efficacy of the drug-delivery system depends on their ability to avoid phagocytosis of endothelial system,cross the biological barriers,prolong circulation life,localize and rapidly release the therapeutic at target sites.In this work,we designed a platelet membrane(PM)-camouflaged hollow mesoporous bismuth selenide nanoparticles(BS NPs)loading with indocyanine green(ICG)(PM@BS-ICG NPs)to achieve the above advantages.PM-coating has active tumor-targe ting ability which could preve nt drug leakage and provide drug long circulation,causing drug delivery systems to accumulate in tumor sites effectively.Moreover,as a type of the photothermal sensitizers,BS NPs are used as the inner cores to improve ICG stability and are served as scaffolds to enhance the hardness of this drug delivery system.For one hand,the thermal vibration of BS NPs under NIR laser irradiation causes tumor inhibition through hyperthermia.For another hand,this hyperthermia process could damage PM and let ICG rapid release from PM@BS-ICG NPs.The in vitro and in vivo results showed that this biomimetic nano-drug delivery system exhibits obvious antitumor activity which has good application prospect.
基金the financial support by the National Natural Science Foundation of China(51631008)the National Key Research and Development Program of China(No.2016YFB0701400)+1 种基金Natural Science Foundation of Shaanxi Province 2020JM-122the National High Technology Research and Development Program of China(No.2012AA03A511)。
文摘The morphological evolution and coarsening kinetics ofγ'precipitates in a Re-containing Ni-based single crystal superalloy were investigated during isothermal aging at 900,950 and 1000℃.After heat treatment,well-defined cuboidalγ'precipitates with low misfit was obtained within the experimental alloy.Then coarsening rate constants and particle size distribution(PSD)ofγ'phases were calculated and specified based on the measured precipitate sizes for va rying periods of aging times from 100 to 2000 h.After aging for 2000 h,γ'precipitates maintained cubical shape at 900℃,while exhibited sphere at 950 and 1000℃.Coarsening models based on diffusion-controlled process with a functional relationship of r^(3) vs.t(classic Lifshitz-Slyozov-Wagner coarsening model)and interface-controlled model with a function of r^(2) vs.t(trans-interface diffusion-controlled coarsening model)were investigated to fit between the experimental results and theoretical analysis.It was found that Re as the slowest diffusing solute in the alloy constituted the rate-limited step for coarsening based on LSW model,while the process limiting coarsening as governed by an interface diffusion process could possibly be related to the Al diffusion through theγ/γ'interface.The PSDs and coarsening exponent were discussed by comparing the experimental data with predictions of LSW and TIDC models.Finally,coarsening mechanism could be divided into four regimes:(i)coarsening by diffusion-controlled;(ii)coarsening by diffusion and interface cocontrolled;(iii)coarsening by interface-controlled;(iv)coarsening by interface-controlled accompanied withγ'coalescence.
文摘Cellulase is a complex enzyme that can decompose cellulose into glucose,and it could effectively treat cellulose waste. In this paper,it aims to explore development status and research progress of cellulase,and introduce concept and action mechanism of cellulase,research situation of cellulase in molecular aspect,application of cellulase,and development of cellulase is also prospected.
基金financially supported by the National Natural Science Foundation of China(Nos.U1804183,81901878 and 81874304)China Postdoctoral Science Foundation(No.2019M662553)Key Scientific Research Project(Education Department of Henan Province,No.20HASTIT049)。
文摘Photothermal therapy(PTT)-induced immune response has attracted much attention,however,which cannot work at full capacity.In this study,the simvastatin(SV)adjuvant is loaded into gold nanocages(AuNCs)to develop a simple drug delivery system,which can efficiently utilize the tumor-associated antigens(TAAs)for improving immune responses.AuNCs/SV-mediated PTT treatment enhances tumor cells damage and promotes the release of TAAs which are immediately captured by Au NCs/SV to form AuNCs/SV/TAAs recombinant nanoparticle.Impressively,AuNCs/SV/TAAs can accumulate in lymph nodes effectively due to the suitable size of~55 nm and hyperthermia-induced vasodilative effect.And the codelivery of antigen and adjuvant is beneficial to stimulating the maturation of dendritic cells for further activating T cells.In a word,the recombinant strategy could make full use of TAAs to produce an individual powerful immunotherapy.
基金supported by the National Natural Science Foundation of China(Nos.21771164,U1804129)the Natural Science Foundation of Henan Province(No.222300420525)the Zhongyuan Youth Talent Support Program of Henan Province
文摘Sodium-ion battery is a potential application system for large-scale energy storage due to the advantage of higher nature abundance and lower production cost of sodium-based materials.However,there exist inevitably the safety problems such as flammability due to the use of the same type of organic liquid electrolyte with lithium-ion battery.Gel polymer electrolytes are being considered as an effective solution to replace conventional organic liquid electrolytes for building safer sodium-ion batteries.In this review paper,the authors present a comprehensive overview of the research progress in electrochemical and physical properties of the gel polymer electrolyte-based sodium batteries.The gel polymer electrolytes based on different polymer hosts namely poly(ethylene oxide),poly(acrylonitrile),poly(methyl methacrylate),poly(vinylidene fluoride),poly(vinylidene fluoride-hexafluoro propylene),and other new polymer networks are summarized.The ionic conductivity,ion transference number,electrochemical window,thermal stability,mechanical property,and interfacial issue with electrodes of gel polymer electrolytes,and the corresponding influence factors are described in detail.Furthermore,the ion transport pathway and ion conduction mechanism are analyzed and discussed.In addition,the advanced gel polymer electrolyte systems including flame-retardant polymer electrolytes,composite gel polymer electrolytes,copolymerization,single-ion conducting polymer electrolytes,etc.with more superior and functional performance are classified and summarized.Finally,the application prospects,development opportunities,remaining challenges,and possible solutions are discussed.
基金supported by National Natural Science Foundation of China(No.22075139)。
文摘Carbon materials derived from biomass waste are considered as potential electrocatalysts for applications in zinc-air batteries(ZABs)due to their low cost and good catalytic activity.Here,we reported the preparation of gel-based catalysts through utilizing hydrolyzed waste leather powder cross-linked with metallic salt solutions.After calcination,iron-nickel alloy anchored in nitrogen-doped porous carbon catalysts(Fe Ni@NDC)was achieved.Compared with commercial Pt/C catalyst,Fe Ni@NDC-800 exhibited lower E_(1/2)(0.77 V)and better durability.More importantly,the resulting Fe Ni@NDC-800-based alkaline ZABs achieved power density of 93.01 m W/cm^(2) and open circuit voltage of 1.45 V,which the Fe Ni@NDC-800-based neutral ZAB displayed a charge/discharge cycle stability of 275 h.This work opens up the possibility of rational design and preparation of low-cost and high-performance electrocatalysts from recyclable leather waste.
基金supported by National Basic Research Program of China under Grants No. 2013CB329002Science Fund for Creative Research Groups of NSFC under Grants No.61321061+3 种基金China's 863 Project under Grants No.2015AA01A706National Major Project under Grants No.2016ZX03001023-003Program for New Century Excellent Talents in University under Grants No.NCET-130321Tsinghua-Qualcomm Joint Research Program,and Tsinghua University Initiative Scientific Research Program under Grants No. 2011THZ02-2
文摘In device-to-device(D2D)underlay cellular networks with downlink spectrum sharing,massive MIMO seems promising as the large number of antennas at the base station(BS) can be utilized to suppress interference.However,the channel state information(CSI) from the BS to D2D receivers is required to obtain this advantage.In this paper,we first propose a novel time division duplex(TDD) scheme for D2D users to acquire this CSI,without additional pilot overhead.Moreover,we propose an interference-aware MMSE precoder utilizing the acquired CSI from the BS to not only cellular users but also D2D users to suppress the cellular-to-D2D interference.Simulation results show that our proposed TDD scheme and precoder can significantly improve the achievable sum spectral efficiency(SE) and D2D SE,compared to the classical MMSE precoder.Compared with the interferenceaware ZF precoder,whose performance severely degrades for large user numbers,our proposed interference-aware MMSE precoder can always guarantees a high and stable performance in terms of achievable SE.
基金This work was supported by the Start-Up Funding for Research of Nanchang Institute of Science and Technology(NGRCZX-22-03)School of Environment and Civil Engineering,Nanchang,Jiangxi,China.
文摘Globally,fossil fuel dependence has created several environmental challenges and climate change.Hence,creating other alternative renewable and ecologically friendly bio-energy sources is necessary.Lignocellulosic biomass has gained significant attention recently as a renewable material for biofuel production.The large amounts of plantain and banana plant parts wasted after harvesting,as well as the peels generated daily by the fruit market and industries,demonstrate the potential of bioenergy resources.This review briefly assesses plantain and banana plant biomass(PBB)generated in the developing,developed,and underdeveloped countries,the consumable parts,and feasible products yield.It emphasized the advantages and disadvantages of the commonly adopted treatment technologies of composting,incineration,and landfilling.Further,the utilization of PBB as catalysts in biodiesel synthesis was briefly highlighted.To optimize recovery of biofuel,different integration routes of pyrolysis,anaerobic digestion,fermentation,hydrothermal carbonization,hydrothermal liquefaction,and hydrothermal gasification for the valorization of the PBB were proposed.The complex compounds present in the PBB(hemicellulose,cellulose,and lignin)can be converted into valuable bio-products such as methane gas and bio-ethanol for bioenergy,and nutrients to promote bioactive ingredients.The investigation of the viability and innovation potential of the integrated routes’technology is necessary to improve the circular bio-economy and the recovery of biofuels from biomass waste,particularly PBB.
基金supported by the Science and Technology Plan of Jiangxi Provincial Health Commission(No.SKJP220201115)Live Science and Technology of Suzhou(No.SS201862)the Prior-ity Academic Program Development of Jiangsu Higher Education Institutions(PAPD).Translational Research Grant of NCRCH(No.2020WSB08).
文摘Inhaled drug-containing nanocarriers have been well applied as an important strategy in pulmonary dis-eases.Acute lung injury(ALI)is characterized by abnormal lung tension and complex pathogenesis,with high mortality because of the limitations of targeted intervention.Accordingly,in the present study,we first identified that the mechanosensitive ion channel Piezo1 participated in the ALI-associated processes induced by lipopolysaccharide(LPS)in vitro and in vivo.Then,chitosan-stabilized bovine serum albu-min nanoparticles(NCs)emulsified with the Piezo1 inhibitor GsMTx4(NC-GsMTx4)were generated and exhibited excellent biocompatibility and biological function.Through aerosol inhalation,NC-GsMTx4 im-proved lung injury and inhibited cell apoptosis in LPS-stressed ALI mice and alleviated pulmonary fibrosis during the later stage of ALI.Mechanistically,GsMTx4 could regulate inflammation and apoptosis in lung epithelial cells via NF-κB and ERK1/2 signaling.In summary,our findings provide new insights into the pathological mechanisms of Piezo1 in ALI progression,and nebulized inhalation of NC-GsMTx4 offers a prospective platform for targeting Piezo1 to treat ALI efficiently and conveniently.
基金supported by the National Natural Science Foundation of China(No.82272847,82202318,82304417,82303529)The Henan Province Fund for Cultivating Advantageous Disciplines(No.222301420012)+2 种基金Central Plains science and technology innovation leading talent project(No.234200510005)The project tackling of key scientific and technical problems of Henan Provine(No.232102311163)China Postdoctoral Science Foundation(2022TQ0310,2023TQ0307,2023M730971)。
文摘Bacterial-based antitumor immunity has become a promising strategy to activate the immune system for fighting cancer.However,the potential application of bacterial therapy is hindered by the presence of instability and susceptibility to infections within bacterial populations.Furthermore,monotherapy is ineffective in completely eliminating complex cancer with multiple contributing factors.In this study,based on our discovery that spore shell(SS)of Bacillus coagulans exhibits excellent tumor-targeting ability and adjuvant activity,we develop a biomimetic spore nanoplatform to boost bacteria-mediated antitumor therapy,chemodynamic therapy and antitumor immunity for synergistic cancer treatment.In detail,SS is separated from probiotic spores and then attached to the surface of liposome(Lipo)that was loaded with hemoglobin(Hb),glucose oxidase(GOx)and JQ1to construct SS@Lipo/Hb/GOx/JQ1.In tumor tissue,highly toxic hydroxyl radicals(·OH)are generated via sequential catalytic reactions:GOx catalyzing glucose into H_(2)O_(2)and Fe^(2+)in Hb decomposing H_(2)O_(2)into·OH.The combination of·OH and SS adjuvant can improve tumor immunogenicity and activate immune system.Meanwhile,JQ1-mediated down-regulation of PD-L1 and Hb-induced hypoxia alleviation synergistically reshape immunosuppressive tumor microenvironment and potentiate immune response.In this manner,SS@Lipo/Hb/GOx/JQ1 significantly suppresses tumor growth and metastasis.To summarize,the nanoplatform represents an optimum strategy to potentiate bacteria-based cancer immunotherapy.
基金supported by the National Natural Science Foundation of China(61472192)the Scientific and Technological Support Project(Society)of Jiangsu Province(BE2016776)
文摘The Internet now is a large-scale platform with big data. Finding truth from a huge dataset has attracted extensive attention, which can maintain the quality of data collected by users and provide users with accurate and efficient data. However, current truth finder algorithms are unsatisfying, because of their low accuracy and complication. This paper proposes a truth finder algorithm based on entity attributes (TFAEA). Based on the iterative computation of source reliability and fact accuracy, TFAEA considers the interactive degree among facts and the degree of dependence among sources, to simplify the typical truth finder algorithms. In order to improve the accuracy of them, TFAEA combines the one-way text similarity and the factual conflict to calculate the mutual support degree among facts. Furthermore, TFAEA utilizes the symmetric saturation of data sources to calculate the degree of dependence among sources. The experimental results show that TFAEA is not only more stable, but also more accurate than the typical truth finder algorithms.
文摘In this paper, the effects of annealing time on the dielectric properties of the Spark Plasma Sintered (SPS) BaMn3Ti4O14.25 pellets were detail studied by the crystal structure analysis, micro structural observation and electrical properties research. The results showed that long annealing time was beneficial to the recovery of crystal structure damage caused by SPS, the formation of a reoxidation layer at the surface of grains and decreasing of the electrically insulating phase. All of these resulted in an increase in dielectric constant and loss, and a reduction in breakdown voltage.
基金supported by the National Basic Research Program of China (No. 2013CB228604)the National Science and Technology Major Project (No. 2011ZX05030-004-002,2011ZX05019-003)the National Natural Science Foundation (No. 41004050)
文摘Forward modeling of elastic wave propagation in porous media has great importance for understanding and interpreting the influences of rock properties on characteristics of seismic wavefield. However,the finite-difference forward-modeling method is usually implemented with global spatial grid-size and time-step; it consumes large amounts of computational cost when small-scaled oil/gas-bearing structures or large velocity-contrast exist underground. To overcome this handicap,combined with variable grid-size and time-step,this paper developed a staggered-grid finite-difference scheme for elastic wave modeling in porous media. Variable finite-difference coefficients and wavefield interpolation were used to realize the transition of wave propagation between regions of different grid-size. The accuracy and efficiency of the algorithm were shown by numerical examples. The proposed method is advanced with low computational cost in elastic wave simulation for heterogeneous oil/gas reservoirs.
