Coking industry is an important volatile organic compounds(VOCs) emission source in China,however,detailed information on VOCs emissions is lacking.Therefore,we selected a typical mechanized coking plant and collected...Coking industry is an important volatile organic compounds(VOCs) emission source in China,however,detailed information on VOCs emissions is lacking.Therefore,we selected a typical mechanized coking plant and collected air samples according to the Emission Standard of Pollutants for Coking Chemical Industry(GB16171-2012).Using gas chromatographymass spectrometry method,we analyzed the VOCs in the air samples,and applied maximum increment reactivity(MIR) rule to estimate ozone formation potential(OFP) of the VOCs emitted from the coke production.More than 90 VOCs species were detected from the coking plant,including alkanes,alkenes,alkynes,aromatic hydrocarbons,halogenated hydrocarbons and oxygenated VOCs.The concentrations of VOCs(p(VOCs)) generated at different stages of the coking process are significantly different.p(VOCs) from coke oven chimney had the highest concentration(87.1 mg/m3),followed by coke pushing(4.0 mg/m3),coal charging(3.3 mg/m3) and coke oven tops(1.1 mg/m3).VOCs species emitted from the coke production processes were dominated by alkanes and alkenes,but the composition proportions were different at the different stages.Alkenes were the most abundant emission species in flue gases of the coke oven chimney accounting for up to 66% of the total VOCs,while the VOCs emissions from coke pushing and coal charging were dominated by alkanes(36% and 42%,respectively),and the alkanes and alkenes emitted from coke oven top were similar(31% and 29%,respectively).Based on above results,reduction of VOCs emissions from coke oven chimney flue gases is suggested to be an effective measure,especially for alkenes.展开更多
Ambient benzene homologues were measured at a site in the northeastern urban area of Beijing, China, from August 24 to September 4, 2012 by SUMMA canister sampling followed by laboratory determination using cryogenic ...Ambient benzene homologues were measured at a site in the northeastern urban area of Beijing, China, from August 24 to September 4, 2012 by SUMMA canister sampling followed by laboratory determination using cryogenic cold trap pre-concentration-GC-MS/FID, and their health risks were also assessed. Daily total benzene homologues ranged from 0.99 to 49.71 μg/m3 with an average of 11.98 μg/m3. Benzene homologues showed higher concentrations in the morning and evening than that at noontime. Comparison with previous studies revealed a trend of decrease for ambient benzene homologues probably due to the effective emission control in Beijing in recent years. Vehicular exhaust was the main source while volatilization of paints and solvents also made substantial contributions. Health risk assessment showed that BTEX （benzene, toluene, ethylbenzene, o-xylene, m-xylene and p-xylene） and styrene had no appreciable adverse non-cancer health risks for the exposed population, while benzene has potential cancer risk of 1.34E-05. Available data from cities in China all implied that benzene imposes relatively higher cancer risk on the exposed populations and therefore strict control measures should be taken to further lower ambient benzene levels in China.展开更多
Owing to rapid economic and industrial development, China has been suffering from degraded air quality and visibility. Volatile organic compounds （VOCs） are important precursors to the formation of ground-level ozon...Owing to rapid economic and industrial development, China has been suffering from degraded air quality and visibility. Volatile organic compounds （VOCs） are important precursors to the formation of ground-level ozone and hence photochemical smog. Some VOCs adversely affect human health. Therefore, VOCs have recently elicited public concern and given new impetus to scientific interest. China is now implementing a series of polices to control VOCs pollution. The key to formulating policy is understanding the ambient VOCs pollution status. This paper mainly analyzes the species, levels, sources, and spatial distributions of VOCs in ambient air. The results show that the concentrations of ambient VOCs in China are much higher than those of developed countries such as the United States and Japan, especial benzene, which exceeds available standards. At the same time, the ozone formation potential （OFP） and secondary organic aerosol formation potential （SOAFP） of various VOCs are calculated. Aromatics and alkenes have much higher OFPs, while aromatics have higher SOAFP. The OFPs of ambient VOCs in the cities of Beijing, Guangzhou and Changchun are very high, and the SOAFP of ambient VOCs in the cities of Hangzhou, Guangzhou and Changchun are higher.展开更多
Emissions derived from the consumption of organic solvents have been proven to be the primary industrial source of volatile organic compounds(VOCs).In conjunction with epidemiologic studies, water-based paints(WBPs) a...Emissions derived from the consumption of organic solvents have been proven to be the primary industrial source of volatile organic compounds(VOCs).In conjunction with epidemiologic studies, water-based paints(WBPs) and solvent-based paints(SBPs) were selected as representatives of newly developed solvents and traditional solvents, respectively,to simulate the effects of consuming solvents emitted during industrial production.And non-carcinogenic and carcinogenic risks to residents near emission sources were studied in detail.The results showed that the spatial distribution of health risks varied with meteorological conditions and type of emission source, and the prevailing wind direction strongly affected the distribution range and shape of the influenced area.The areas of influence maximized on heavy-polluting days for both WBP and SBP emission sources with the total span reaching 804 m and 16 km, respectively;meanwhile, the areas of influence for carcinogenic risk resulting from WBP emission sources were 1.2 and 2.3 times greater than those measured on fine and rainy days, respectively, and 1.8 and 2.9 times greater for SBP emission sources.Compared with WBPs, the total spans of negatively influenced regions resulting from SBP emission sources were 10.4, 12.5 and 19.9 times greater on fine, rainy and heavypolluting days, respectively.Therefore, carcinogenic risk was the dominant health threat for populations residing close to solvent-consuming industrial emission sources.The findings suggest that newly developed solvents are capable of significantly reducing consequent health threats, nevertheless, they could still pose occasional threats to nearby residents under specific meteorological conditions.展开更多
Figs(Ficus, Moraceae) and their pollinating fig wasps(Hymenoptera, Agaonidae, Chalcidoidea) are a striking example of obligate mutualism and coevolution. Agaonid females enter the figs to lay their eggs,but also activ...Figs(Ficus, Moraceae) and their pollinating fig wasps(Hymenoptera, Agaonidae, Chalcidoidea) are a striking example of obligate mutualism and coevolution. Agaonid females enter the figs to lay their eggs,but also actively or passively transport pollen into the figs at the same time. We examined eight related fig tree species pollinated by host specific Eupristina agaonids to determine the relationships between pollination mode, host pollen, ovule ratios and the ability of the figs to recruit additional non-agaonid pollinators. Uniquely amongst the eight Eupristina species, the pollinator of Ficus curtipes has nonfunctional pollen pockets and no coxal combs, showing that it pollinates passively. Reflecting this, the anther-to-ovule ratio of F. curtipes is unusually high.In addition to the agaonids, figs support many species of 'non-pollinating fig wasps'(NPFW) that are typically ovule gallers or parasitoids. These mainly oviposit from outside the figs but there are a few species of NPFW that are like agaonids and enter the figs to oviposit. Two of the eight Eupristina pollinated fig trees support host specific internally-ovipositing fig wasps belonging to the chalcidoid genera Diaziella(Sycoecinae) and Lipothymus(Otitesellinae). Reflecting the trees' pollination modes, these fig wasps act as supplementary pollinators of F. curtipes, but not of Ficus glaberrima, where agaonid pollination is active.展开更多
Oct4 is one of the key pluripotent factors essential for embryonic stem cells and induced pluripotent stem （iPS） cells. Oct4 belongs to the POU domain family, which contains multiples genes with various important fu...Oct4 is one of the key pluripotent factors essential for embryonic stem cells and induced pluripotent stem （iPS） cells. Oct4 belongs to the POU domain family, which contains multiples genes with various important functions. Although the function of Oct4 has been extensively studied, detailed comparison of Oct4 with other POU family genes and their evolutionary analysis are still lacking. Here, we systematically identified POU family genes from lower to higher animal species. We observed an expansion of POU family genes in vertebrates, with an additional increment in mammalian genomes. We analyzed the phylogenetic relationship, tissue specific expression profiles and regulatory networks of POU family genes of the human genome, and predicted the putative binding microRNAs of human POU family genes. These results provide the first comprehensive evolutionary and comparative analysis of POU family genes, which will help to better understand the relationships among POU family genes and shed light on their future functional studies.展开更多
According to characteristics of General Entomology and existing problems in teaching process,it came up with methods and countermeasures for improving teaching General Entomology,including improving practical ability ...According to characteristics of General Entomology and existing problems in teaching process,it came up with methods and countermeasures for improving teaching General Entomology,including improving practical ability of students through enhancing all links of practice teaching,and stimulating learning interest of students through improving methods of course examination.展开更多
Firstly,the status quo of low-carbon agriculture development in China was analyzed,and then advanced experience of developed countries in low-carbon agriculture development was introduced,finally ways of developing lo...Firstly,the status quo of low-carbon agriculture development in China was analyzed,and then advanced experience of developed countries in low-carbon agriculture development was introduced,finally ways of developing low-carbon agriculture in China were put forward.展开更多
The global automotive industry demands world-class levels of product quality, productivity, and competitiveness as well as continual improvement. To achieve this goal,?many vehicle manufacturers companies use?quality ...The global automotive industry demands world-class levels of product quality, productivity, and competitiveness as well as continual improvement. To achieve this goal,?many vehicle manufacturers companies use?quality control tools to improve the quality of the product with zero defects and highly satisfied to the customer. Nowadays, there are a lot of quality tools applied to solve the problem quickly but it’s still the fact to find out good and efficient solving way. The study emphasizes the identification of potential failure which failures may have encountered in the production process and it will lead to car scrap, rework and influence of the internal production and quality target. After the complete study of the manufacturing process and production data-failure causes, failure rate and data etc. FMEA discover the weak processes in the form of higher risk priority number in the manufacturing of the car painting process, which required reducing by identifying and implementing of the defects and this will improve the process quality of the painting surface of the car. To analysis, the improvement of the car surface defects SPC (Statistical Process Control) tools are more efficient where can easily visible the defects trends. SPC chart is chronological graphs of process data that are used in manufactures industries to help understand, control and improve the process and that although based on statistical theory area easy for practitioners to use and interpret. In order to orient goal of zero defects of the car, surface uses the PFMEA technique to prioritize?the defects and statistically analyze the roots cause of the defect and control the defects through continues improvements process.展开更多
Dongguan is an important industrial city, located in the Pearl River Delta, South China. Recently, Dongguan city experienced a rapid urban growth with the locational advantage by transforming from traditional agricult...Dongguan is an important industrial city, located in the Pearl River Delta, South China. Recently, Dongguan city experienced a rapid urban growth with the locational advantage by transforming from traditional agricultural region to modern manufacturing metropolis. The urban transformation became the usual change in China under the background of urbanization which belongs to one trend of globalization in the 21st century. This paper tries to analyze urban growth simulation based on remotely sensed data of previous years and the related physical and socio-economic factors and predict future urban growth in 2024. The study examined and compared the land use/cover (LUC) changes over time based on produced maps of 2004, 2009, and 2014. The results showed that water and forest area decreased since the past years. In contrast, the urban land increased from 2004 to 2014, and this increasing trend will continue to the future years through the urbanization process. Having understood the spatiotemporal trends of urban growth, the study simulated the urban growth of Dongguan city for 2024 using neural network simulation technique. Further, the figure of merit (FoM) of simulated map of 2014 map was 8.86%, which can be accepted in the simulation and used in the prediction process. Based on the consideration of water body and forest, the newly growth area is located in the west, northeast, and southeast regions of Dongguan city. The finding can help us to understand which areas are going to be considered in the future urban planning and policy by the local government.展开更多
Alteration in skin microbiome profile is involved in many skin conditions, therefore, microbiome modulation is a reasonable target for skin health. Probiotic skincare was suggested, and leave-on synbiotic skincare pre...Alteration in skin microbiome profile is involved in many skin conditions, therefore, microbiome modulation is a reasonable target for skin health. Probiotic skincare was suggested, and leave-on synbiotic skincare preparation, blending bacillus spores, as probiotic active ingredient, and inulin sugar, as prebiotic booster, is evaluated, using microarray, 16S gene sequencing, and clinical skin analyses. Topical application of leave-on synbiotic skincare on skin model activates a profound effect on skin biology, expressed in the transcriptome level, with higher than 10% affected genes. The significance of the synbiotic preparation on skin biology was assured, indicating the involvement of major biological pathways. Blending probiotic with Polygonum aviculare plant extract, had triggered a distinct gene expression alteration, demonstrating the sensitivity of skin responses to different active substances. A synbiotic skincare application, had successfully introduced live and active Bacillus probiotics on human skin, detectable days after application was finalized. Following synbiotic application, the microbial content of several microorganisms, related to skin pathologies, was reduced, while the content of bacillus species, representing a healthier microbiome status, was increased, suggesting that frequent application may lead to overall healthier skin microbiome. Acne vulgaris involves unbalanced skin microbiome, with expansion of Cutibacterium acnes. The efficacy of a synbiotic skin cream was assessed to improve acne symptoms, including IGA dermatologist acne severity score, the number of counted acne lesions, measured skin oiliness and skin redness, visual appearance of skin-pores, skin smoothness and softness, and Acne Quality of Life Index.展开更多
Acute morphological changes in de novo coronary lesions after drug-coated balloon(DCB)angioplasty can affect endothelial mechanics and consequently clinical outcomes.Angiography-based computational modeling has been v...Acute morphological changes in de novo coronary lesions after drug-coated balloon(DCB)angioplasty can affect endothelial mechanics and consequently clinical outcomes.Angiography-based computational modeling has been validated to assess endothelial dynamic strain(EDS)in coronary arteries in vivo.The EDS was calculated on the basis of pre-and post-DCB angiography.Parameters of quantitative coronary angiography and EDS were quantified at cross-sections in the treated segments.A total of 336 and 348 lesion cross-sections were included in the small/large vessel groups,respectively.The acute lumen gain after DCB was significantly higher in large than small vessels(relative changes:21.3%[17.4%,25.1%]vs.7.4%[4.8%,10.1%],P<0.001).Before treatment,three indices of EDS were significantly higher in small than large vessels(for ED-EDS:29.2%[19.8%,44.8%]vs.20.4%[14.3%,30.2%];for ES-EDS:26.8%[18.9%,37.7%]vs.18.3%[13.9%,25.4%];for TA-EDS:19.1%[13.9%,27.8%]vs.14.3%[10.5%,20.1%],P<0.001).After treatment,the EDS in small vessels significantly decreased(P<0.001).ED-EDS showed the highest correlation with pre-DCB DSP(r=0.43,P<0.001)and post-DCB MLD(r=0.35,P<0.001).The levels of EDS parameters for small or large vessel lesions significantly differed.Further study is required to examine the clinical value of EDS in predicting cardiac events after DCB treatment.展开更多
Balloon rupture during transcatheter aortic valve replacement(TAVR)is a rare but serious complication.Here,we present two cases of balloon rupture in patients with severe aortic stenosis and type 0 bicuspid aortic val...Balloon rupture during transcatheter aortic valve replacement(TAVR)is a rare but serious complication.Here,we present two cases of balloon rupture in patients with severe aortic stenosis and type 0 bicuspid aortic valves.Three-dimensional models based on pre-procedure cardiac CT angiography were used to investigate these cases post hoc.The models revealed asymmetrical distribution of calcifications with sharply spiked features in the bicuspid aortic valves.The narrow calcified orifices resulted in uneven force distribution on the expanded balloon,thus leading to balloon rupture.We additionally review the classification and causes of balloon rupture,summarize methods for avoiding com-plications,and describe treatment options.Accurate pre-procedural anatomy evaluation and computer modeling are crucial for planning and managing TAVR procedures.Further investigation through computer simulation is necessary to determine the appropriate balloon size and inflation locations,to provide a reference for pre-procedural preparation.展开更多
I.EXECUTIVE SUMMARY next-generation,high-intensity electron-positron collider"Higgs factory",such as the Circular Electron-Positron Collider(CEPC),is among the highest priorities for the global high-energy c...I.EXECUTIVE SUMMARY next-generation,high-intensity electron-positron collider"Higgs factory",such as the Circular Electron-Positron Collider(CEPC),is among the highest priorities for the global high-energy collider physics community.The CEPC can provide unprecedented opportunities for making fundamental discoveries and providing decisive insights in the quest for a"New Standard Model(SM)"of nature's fundamental interactions.The CEPC could:·Identify the origin of matter,especially the mechanism related to the first-order phase transition in the early Universe,which could produce a detectable gravitational wave signal.展开更多
The article "Data-driven soft sensors in blast furnace ironmaking:a survey,"written by Yueyang LUO,Xinmin ZHANG,Manabu KANO,Long DENG,Chunjie YANG,and Zhihuan SONG,was originally published electronically on ...The article "Data-driven soft sensors in blast furnace ironmaking:a survey,"written by Yueyang LUO,Xinmin ZHANG,Manabu KANO,Long DENG,Chunjie YANG,and Zhihuan SONG,was originally published electronically on the publisher's Internet portal on Mar.27,2023 without open access.展开更多
Deep learning has empowered traffic prediction models to integrate diverse auxiliary data sources,such as weather and temporal features,for enhanced forecasting accuracy.However,existing approaches often suffer from l...Deep learning has empowered traffic prediction models to integrate diverse auxiliary data sources,such as weather and temporal features,for enhanced forecasting accuracy.However,existing approaches often suffer from limited generality and scalability,and the field lacks a unified benchmark for fair model comparison.This absence hinders consistent performance evaluation,slows the development of robust and adaptable models,and makes it challenging to quantify the incremental benefits of different auxiliary data sources.To address these issues,we present MltAuxTSPP,a unified benchmark framework for deep learning-based traffic state prediction with multi-source auxiliary data.The framework features a standardized data container and a fusion embedding module,enabling consistent utilization of heterogeneous data and improving scalability.It produces unified hidden representations that can be seamlessly adopted by various downstream models,ensuring fair and reproducible comparisons under identical conditions.Extensive experiments on real-world datasets demonstrate that MltAuxTSPP effectively leverages weather and temporal features to improve long-term forecast performance and offers a practical and reproducible foundation for advancing research in traffic state prediction.展开更多
Accurately predicting ocean eddy lifetimes is challenging due to their nonlinear energy dynamics and complex environmental interactions.This study utilizes a global ocean eddy trajectory dataset to analyse spatio-temp...Accurately predicting ocean eddy lifetimes is challenging due to their nonlinear energy dynamics and complex environmental interactions.This study utilizes a global ocean eddy trajectory dataset to analyse spatio-temporal dynamics,from energy accumulation to dissipation,identifying key lifetime factors:self energy,spatial distribution,and seasonal variability.We propose the first deep learning framework(ELPNet)designed to model the complete lifetimes of mesoscale eddies.lt employs an adaptive time-series dimensionality reduction technique to present the dynamic evolution of eddies in a real-time and normalized manner.Furthermore,it integrates Long Short-Term Memory(LSTM)networks and Transformer models within a U-shaped encoder-decoder architecture to capture multi-scale spatio-temporal patterns,thereby enhancing the representation capability of eddies'complete lifecycles.To address limitations of conventional metrics for nonlinear dissipation,we introduce the Eddy Lifetime Prediction Accuracy(ELPA)metric.With ELPA at a 30%tolerance,ELPNet achieves 71.2%prediction accuracy,doubling the performance of traditional methods.Error analysis highlights seafloor topography,energy dissipation rates,and eddy survival stages as primary accuracy constraints.This scalable approach extends to forecasting other oceanic phenomena like ocean fronts and internal waves,thereby enhancing intelligent ocean science forecasting systems.展开更多
The recently released data of DESI DR2 favors a dynamical dark energy theory,with the equation of state crossing the cosmological constant boundary w=-1.In this paper,we briefly review quintom cosmology,especially the...The recently released data of DESI DR2 favors a dynamical dark energy theory,with the equation of state crossing the cosmological constant boundary w=-1.In this paper,we briefly review quintom cosmology,especially the quintom bounce.We will give three examples of a quintom bounce and one example of a cyclic universe with quintom matter.展开更多
基金supported by National Research Program for Key Issues in Air Pollution Control in China(No.DQGG0524)
文摘Coking industry is an important volatile organic compounds(VOCs) emission source in China,however,detailed information on VOCs emissions is lacking.Therefore,we selected a typical mechanized coking plant and collected air samples according to the Emission Standard of Pollutants for Coking Chemical Industry(GB16171-2012).Using gas chromatographymass spectrometry method,we analyzed the VOCs in the air samples,and applied maximum increment reactivity(MIR) rule to estimate ozone formation potential(OFP) of the VOCs emitted from the coke production.More than 90 VOCs species were detected from the coking plant,including alkanes,alkenes,alkynes,aromatic hydrocarbons,halogenated hydrocarbons and oxygenated VOCs.The concentrations of VOCs(p(VOCs)) generated at different stages of the coking process are significantly different.p(VOCs) from coke oven chimney had the highest concentration(87.1 mg/m3),followed by coke pushing(4.0 mg/m3),coal charging(3.3 mg/m3) and coke oven tops(1.1 mg/m3).VOCs species emitted from the coke production processes were dominated by alkanes and alkenes,but the composition proportions were different at the different stages.Alkenes were the most abundant emission species in flue gases of the coke oven chimney accounting for up to 66% of the total VOCs,while the VOCs emissions from coke pushing and coal charging were dominated by alkanes(36% and 42%,respectively),and the alkanes and alkenes emitted from coke oven top were similar(31% and 29%,respectively).Based on above results,reduction of VOCs emissions from coke oven chimney flue gases is suggested to be an effective measure,especially for alkenes.
基金supported by the Special Research Project for the National Environmental Protection Public Welfare Industry of China(No.201009032)the Strategic Pilot Science and Technology Project of Chinese Academy of Sciences(Class B)(No.XDB05010200)the Project of National Natural Science Foundation of China(No.41175111)
文摘Ambient benzene homologues were measured at a site in the northeastern urban area of Beijing, China, from August 24 to September 4, 2012 by SUMMA canister sampling followed by laboratory determination using cryogenic cold trap pre-concentration-GC-MS/FID, and their health risks were also assessed. Daily total benzene homologues ranged from 0.99 to 49.71 μg/m3 with an average of 11.98 μg/m3. Benzene homologues showed higher concentrations in the morning and evening than that at noontime. Comparison with previous studies revealed a trend of decrease for ambient benzene homologues probably due to the effective emission control in Beijing in recent years. Vehicular exhaust was the main source while volatilization of paints and solvents also made substantial contributions. Health risk assessment showed that BTEX （benzene, toluene, ethylbenzene, o-xylene, m-xylene and p-xylene） and styrene had no appreciable adverse non-cancer health risks for the exposed population, while benzene has potential cancer risk of 1.34E-05. Available data from cities in China all implied that benzene imposes relatively higher cancer risk on the exposed populations and therefore strict control measures should be taken to further lower ambient benzene levels in China.
基金supported by the National Science & Technology Pillar Program(No.2014BAC23B00,2014BAC23B01)the National Department Public Benefit Research Foundation(Ministry of Environmental Protection of the People's Republic of China)(No.201009032,201307121,201409005)
文摘Owing to rapid economic and industrial development, China has been suffering from degraded air quality and visibility. Volatile organic compounds （VOCs） are important precursors to the formation of ground-level ozone and hence photochemical smog. Some VOCs adversely affect human health. Therefore, VOCs have recently elicited public concern and given new impetus to scientific interest. China is now implementing a series of polices to control VOCs pollution. The key to formulating policy is understanding the ambient VOCs pollution status. This paper mainly analyzes the species, levels, sources, and spatial distributions of VOCs in ambient air. The results show that the concentrations of ambient VOCs in China are much higher than those of developed countries such as the United States and Japan, especial benzene, which exceeds available standards. At the same time, the ozone formation potential （OFP） and secondary organic aerosol formation potential （SOAFP） of various VOCs are calculated. Aromatics and alkenes have much higher OFPs, while aromatics have higher SOAFP. The OFPs of ambient VOCs in the cities of Beijing, Guangzhou and Changchun are very high, and the SOAFP of ambient VOCs in the cities of Hangzhou, Guangzhou and Changchun are higher.
基金supported by the International Research Center of Big Data for Sustainable Development Goals [grant number CBAS2022GSP01]the National Natural Science Foundation of China [grant numbers 42276203 and 42030406]+1 种基金the Natural Science Foundation of Shandong Province [grant number ZR2021MD001]the Laoshan Laboratory [grant number LSKJ202204302].
基金supported by the Ministry of Science and Technology of the People’s Republic of China (No.2020YFC1806303)the Beijing Municipal Science & Technology Commission (No.Z171100004417029)。
文摘Emissions derived from the consumption of organic solvents have been proven to be the primary industrial source of volatile organic compounds(VOCs).In conjunction with epidemiologic studies, water-based paints(WBPs) and solvent-based paints(SBPs) were selected as representatives of newly developed solvents and traditional solvents, respectively,to simulate the effects of consuming solvents emitted during industrial production.And non-carcinogenic and carcinogenic risks to residents near emission sources were studied in detail.The results showed that the spatial distribution of health risks varied with meteorological conditions and type of emission source, and the prevailing wind direction strongly affected the distribution range and shape of the influenced area.The areas of influence maximized on heavy-polluting days for both WBP and SBP emission sources with the total span reaching 804 m and 16 km, respectively;meanwhile, the areas of influence for carcinogenic risk resulting from WBP emission sources were 1.2 and 2.3 times greater than those measured on fine and rainy days, respectively, and 1.8 and 2.9 times greater for SBP emission sources.Compared with WBPs, the total spans of negatively influenced regions resulting from SBP emission sources were 10.4, 12.5 and 19.9 times greater on fine, rainy and heavypolluting days, respectively.Therefore, carcinogenic risk was the dominant health threat for populations residing close to solvent-consuming industrial emission sources.The findings suggest that newly developed solvents are capable of significantly reducing consequent health threats, nevertheless, they could still pose occasional threats to nearby residents under specific meteorological conditions.
基金funded by the National Natural Science Foundation of China(30571507,30670358)
文摘Figs(Ficus, Moraceae) and their pollinating fig wasps(Hymenoptera, Agaonidae, Chalcidoidea) are a striking example of obligate mutualism and coevolution. Agaonid females enter the figs to lay their eggs,but also actively or passively transport pollen into the figs at the same time. We examined eight related fig tree species pollinated by host specific Eupristina agaonids to determine the relationships between pollination mode, host pollen, ovule ratios and the ability of the figs to recruit additional non-agaonid pollinators. Uniquely amongst the eight Eupristina species, the pollinator of Ficus curtipes has nonfunctional pollen pockets and no coxal combs, showing that it pollinates passively. Reflecting this, the anther-to-ovule ratio of F. curtipes is unusually high.In addition to the agaonids, figs support many species of 'non-pollinating fig wasps'(NPFW) that are typically ovule gallers or parasitoids. These mainly oviposit from outside the figs but there are a few species of NPFW that are like agaonids and enter the figs to oviposit. Two of the eight Eupristina pollinated fig trees support host specific internally-ovipositing fig wasps belonging to the chalcidoid genera Diaziella(Sycoecinae) and Lipothymus(Otitesellinae). Reflecting the trees' pollination modes, these fig wasps act as supplementary pollinators of F. curtipes, but not of Ficus glaberrima, where agaonid pollination is active.
基金supported by the grants from the Ministry of Science and Technology of China(No.2011CBA01101 to X.-J.W.)the Chinese Academy of Sciences(Nos. XDA01020105,KSCX2-EW-R-01-03 and 2010-Biols-CAS- 0303 to X.-J.W.)
文摘Oct4 is one of the key pluripotent factors essential for embryonic stem cells and induced pluripotent stem （iPS） cells. Oct4 belongs to the POU domain family, which contains multiples genes with various important functions. Although the function of Oct4 has been extensively studied, detailed comparison of Oct4 with other POU family genes and their evolutionary analysis are still lacking. Here, we systematically identified POU family genes from lower to higher animal species. We observed an expansion of POU family genes in vertebrates, with an additional increment in mammalian genomes. We analyzed the phylogenetic relationship, tissue specific expression profiles and regulatory networks of POU family genes of the human genome, and predicted the putative binding microRNAs of human POU family genes. These results provide the first comprehensive evolutionary and comparative analysis of POU family genes, which will help to better understand the relationships among POU family genes and shed light on their future functional studies.
文摘According to characteristics of General Entomology and existing problems in teaching process,it came up with methods and countermeasures for improving teaching General Entomology,including improving practical ability of students through enhancing all links of practice teaching,and stimulating learning interest of students through improving methods of course examination.
基金Supported by the Planning Project of Philosophy and Social Sciences in Beijing City in 2011(11JGB035)Soft Science Subject of Henan Province in 2013(132400410012)
文摘Firstly,the status quo of low-carbon agriculture development in China was analyzed,and then advanced experience of developed countries in low-carbon agriculture development was introduced,finally ways of developing low-carbon agriculture in China were put forward.
文摘The global automotive industry demands world-class levels of product quality, productivity, and competitiveness as well as continual improvement. To achieve this goal,?many vehicle manufacturers companies use?quality control tools to improve the quality of the product with zero defects and highly satisfied to the customer. Nowadays, there are a lot of quality tools applied to solve the problem quickly but it’s still the fact to find out good and efficient solving way. The study emphasizes the identification of potential failure which failures may have encountered in the production process and it will lead to car scrap, rework and influence of the internal production and quality target. After the complete study of the manufacturing process and production data-failure causes, failure rate and data etc. FMEA discover the weak processes in the form of higher risk priority number in the manufacturing of the car painting process, which required reducing by identifying and implementing of the defects and this will improve the process quality of the painting surface of the car. To analysis, the improvement of the car surface defects SPC (Statistical Process Control) tools are more efficient where can easily visible the defects trends. SPC chart is chronological graphs of process data that are used in manufactures industries to help understand, control and improve the process and that although based on statistical theory area easy for practitioners to use and interpret. In order to orient goal of zero defects of the car, surface uses the PFMEA technique to prioritize?the defects and statistically analyze the roots cause of the defect and control the defects through continues improvements process.
文摘Dongguan is an important industrial city, located in the Pearl River Delta, South China. Recently, Dongguan city experienced a rapid urban growth with the locational advantage by transforming from traditional agricultural region to modern manufacturing metropolis. The urban transformation became the usual change in China under the background of urbanization which belongs to one trend of globalization in the 21st century. This paper tries to analyze urban growth simulation based on remotely sensed data of previous years and the related physical and socio-economic factors and predict future urban growth in 2024. The study examined and compared the land use/cover (LUC) changes over time based on produced maps of 2004, 2009, and 2014. The results showed that water and forest area decreased since the past years. In contrast, the urban land increased from 2004 to 2014, and this increasing trend will continue to the future years through the urbanization process. Having understood the spatiotemporal trends of urban growth, the study simulated the urban growth of Dongguan city for 2024 using neural network simulation technique. Further, the figure of merit (FoM) of simulated map of 2014 map was 8.86%, which can be accepted in the simulation and used in the prediction process. Based on the consideration of water body and forest, the newly growth area is located in the west, northeast, and southeast regions of Dongguan city. The finding can help us to understand which areas are going to be considered in the future urban planning and policy by the local government.
文摘Alteration in skin microbiome profile is involved in many skin conditions, therefore, microbiome modulation is a reasonable target for skin health. Probiotic skincare was suggested, and leave-on synbiotic skincare preparation, blending bacillus spores, as probiotic active ingredient, and inulin sugar, as prebiotic booster, is evaluated, using microarray, 16S gene sequencing, and clinical skin analyses. Topical application of leave-on synbiotic skincare on skin model activates a profound effect on skin biology, expressed in the transcriptome level, with higher than 10% affected genes. The significance of the synbiotic preparation on skin biology was assured, indicating the involvement of major biological pathways. Blending probiotic with Polygonum aviculare plant extract, had triggered a distinct gene expression alteration, demonstrating the sensitivity of skin responses to different active substances. A synbiotic skincare application, had successfully introduced live and active Bacillus probiotics on human skin, detectable days after application was finalized. Following synbiotic application, the microbial content of several microorganisms, related to skin pathologies, was reduced, while the content of bacillus species, representing a healthier microbiome status, was increased, suggesting that frequent application may lead to overall healthier skin microbiome. Acne vulgaris involves unbalanced skin microbiome, with expansion of Cutibacterium acnes. The efficacy of a synbiotic skin cream was assessed to improve acne symptoms, including IGA dermatologist acne severity score, the number of counted acne lesions, measured skin oiliness and skin redness, visual appearance of skin-pores, skin smoothness and softness, and Acne Quality of Life Index.
基金supported by the Zhejiang Provincial Natural Science Foundation of China(LTGY24H180019)Basic Medical and Health Science Technology Projects of Wenzhou City(Y20220132)Medical and Health Science and Technology Project of Zhejiang Province(2023RC210 and 2024KY160).
文摘Acute morphological changes in de novo coronary lesions after drug-coated balloon(DCB)angioplasty can affect endothelial mechanics and consequently clinical outcomes.Angiography-based computational modeling has been validated to assess endothelial dynamic strain(EDS)in coronary arteries in vivo.The EDS was calculated on the basis of pre-and post-DCB angiography.Parameters of quantitative coronary angiography and EDS were quantified at cross-sections in the treated segments.A total of 336 and 348 lesion cross-sections were included in the small/large vessel groups,respectively.The acute lumen gain after DCB was significantly higher in large than small vessels(relative changes:21.3%[17.4%,25.1%]vs.7.4%[4.8%,10.1%],P<0.001).Before treatment,three indices of EDS were significantly higher in small than large vessels(for ED-EDS:29.2%[19.8%,44.8%]vs.20.4%[14.3%,30.2%];for ES-EDS:26.8%[18.9%,37.7%]vs.18.3%[13.9%,25.4%];for TA-EDS:19.1%[13.9%,27.8%]vs.14.3%[10.5%,20.1%],P<0.001).After treatment,the EDS in small vessels significantly decreased(P<0.001).ED-EDS showed the highest correlation with pre-DCB DSP(r=0.43,P<0.001)and post-DCB MLD(r=0.35,P<0.001).The levels of EDS parameters for small or large vessel lesions significantly differed.Further study is required to examine the clinical value of EDS in predicting cardiac events after DCB treatment.
基金This study was funded by the Basic Medical and Health Science Technology Projects of Wenzhou City(Y20220132)the Medical and Health Science and Technology Project of Zhejiang Province(2023RC210).
文摘Balloon rupture during transcatheter aortic valve replacement(TAVR)is a rare but serious complication.Here,we present two cases of balloon rupture in patients with severe aortic stenosis and type 0 bicuspid aortic valves.Three-dimensional models based on pre-procedure cardiac CT angiography were used to investigate these cases post hoc.The models revealed asymmetrical distribution of calcifications with sharply spiked features in the bicuspid aortic valves.The narrow calcified orifices resulted in uneven force distribution on the expanded balloon,thus leading to balloon rupture.We additionally review the classification and causes of balloon rupture,summarize methods for avoiding com-plications,and describe treatment options.Accurate pre-procedural anatomy evaluation and computer modeling are crucial for planning and managing TAVR procedures.Further investigation through computer simulation is necessary to determine the appropriate balloon size and inflation locations,to provide a reference for pre-procedural preparation.
基金the Natural Science Foundation of China(NSFC)(11905162,12035008,12075097,12075123,12090060,12090064,12105248,12135006,12175039,12205227,12205312,12205387,12205171,12235008,12321005,12235001,12305094,12305115,12335005,12375091,12375094,12375096,11975129,12375194,12447167,12475094,12475101,12475106,12475111,12425506,12375101,12405119,12405101,12505121,12135007,12175218,12075213,12335005,12175243,12533001,12125503,12305103,12505120,12575099,12505122,12342502,12575106,12147214,W2432006,W2441004)the National Key R&D Program of China(2024YFA1610603)+22 种基金the China Postdoctoral Science Foundation(2023M732255,2025M773403,GZC20231613)the Natural Science Foundation of Jiangsu Province(BK20210201)the Natural Science Foundation of Henan(Distinguished Young Scholars of Henan Province)(242300421046)the Natural Science Foundation of Sichuan Province(2025ZNSFSC0880)the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030008)the Department of Science and Technology of Shandong province(tsqn202312052,2024HWYQ-005)the Startup Research Fund of Henan Academy of Sciences(20251820001)the Excellent Young Talents Program of Wuhan University of Technology(40122102)the research program of the Wuhan University of Technology(3120625397,2020IB024)the Fundamental Research Funds for the Central Universities(JZ2023HGTB0222,WUT:2022IVA052)the Excellent Scholar Project of Southeast University(Class A)the Big Data Computing Center of Southeast University,National Science and Technology Council,the Ministry of Education(Higher Education Sprout Project NTU-114L104022-1)the Center for Theoretical Sciences of Taiwan,and Vietnam National Foundation for Science and Technology Development(NAFOSTED)(103.01-2023.50)the Research Office of the University of the Witwatersrand and South African Department of Science and Innovation through the SA-CERN programthe self-determined research funds of Central China Normal University from the colleges'basic research and operation of MOE(CCNU24AI003)SJTU Double First Class start-up fund(WF220442604)the Innovation Capability Support Program of Shaanxi(2021KJXX-47)the Slovenian Research Agency under the research core funding No.P1-0035,the research grants J1-3013,N1-0253,CONICET,ANPCyT under project(PICT-2021-00374)Higher Education Sprout Project(NTU-114L104022-1)KIAS Individual Grants(PG086002)at the Korea Institute for Advanced Study,FAPESP(2021/09547-9)the Slovenian Research Agency under the research core funding(P1-0035)research grants J1-3013,N1-0253the bilateral project Proteus PR-12696/Projet 50194VC。
文摘I.EXECUTIVE SUMMARY next-generation,high-intensity electron-positron collider"Higgs factory",such as the Circular Electron-Positron Collider(CEPC),is among the highest priorities for the global high-energy collider physics community.The CEPC can provide unprecedented opportunities for making fundamental discoveries and providing decisive insights in the quest for a"New Standard Model(SM)"of nature's fundamental interactions.The CEPC could:·Identify the origin of matter,especially the mechanism related to the first-order phase transition in the early Universe,which could produce a detectable gravitational wave signal.
文摘The article "Data-driven soft sensors in blast furnace ironmaking:a survey,"written by Yueyang LUO,Xinmin ZHANG,Manabu KANO,Long DENG,Chunjie YANG,and Zhihuan SONG,was originally published electronically on the publisher's Internet portal on Mar.27,2023 without open access.
基金supported by the National Science and Technology Major Project of China(No.2022ZD0120003)。
文摘Deep learning has empowered traffic prediction models to integrate diverse auxiliary data sources,such as weather and temporal features,for enhanced forecasting accuracy.However,existing approaches often suffer from limited generality and scalability,and the field lacks a unified benchmark for fair model comparison.This absence hinders consistent performance evaluation,slows the development of robust and adaptable models,and makes it challenging to quantify the incremental benefits of different auxiliary data sources.To address these issues,we present MltAuxTSPP,a unified benchmark framework for deep learning-based traffic state prediction with multi-source auxiliary data.The framework features a standardized data container and a fusion embedding module,enabling consistent utilization of heterogeneous data and improving scalability.It produces unified hidden representations that can be seamlessly adopted by various downstream models,ensuring fair and reproducible comparisons under identical conditions.Extensive experiments on real-world datasets demonstrate that MltAuxTSPP effectively leverages weather and temporal features to improve long-term forecast performance and offers a practical and reproducible foundation for advancing research in traffic state prediction.
基金supported by the National Natural Science Foundation of China[Nos.42276203,42530404]the Laoshan Laboratory[No.LSKJ202204302]the Natural Science Foundation of Shandong Province[No.ZR2021MD001].
文摘Accurately predicting ocean eddy lifetimes is challenging due to their nonlinear energy dynamics and complex environmental interactions.This study utilizes a global ocean eddy trajectory dataset to analyse spatio-temporal dynamics,from energy accumulation to dissipation,identifying key lifetime factors:self energy,spatial distribution,and seasonal variability.We propose the first deep learning framework(ELPNet)designed to model the complete lifetimes of mesoscale eddies.lt employs an adaptive time-series dimensionality reduction technique to present the dynamic evolution of eddies in a real-time and normalized manner.Furthermore,it integrates Long Short-Term Memory(LSTM)networks and Transformer models within a U-shaped encoder-decoder architecture to capture multi-scale spatio-temporal patterns,thereby enhancing the representation capability of eddies'complete lifecycles.To address limitations of conventional metrics for nonlinear dissipation,we introduce the Eddy Lifetime Prediction Accuracy(ELPA)metric.With ELPA at a 30%tolerance,ELPNet achieves 71.2%prediction accuracy,doubling the performance of traditional methods.Error analysis highlights seafloor topography,energy dissipation rates,and eddy survival stages as primary accuracy constraints.This scalable approach extends to forecasting other oceanic phenomena like ocean fronts and internal waves,thereby enhancing intelligent ocean science forecasting systems.
基金supported by the National Key R&D Program of China Grant No.2021YFC2203100the National Natural Science Foundation of China No.12575053+1 种基金supported by the Higher Education and Science Committee of the Republic of Armenia(Research Project No.24RL-1C047)supported by the National Natural Science Foundation of China No.12403005。
文摘The recently released data of DESI DR2 favors a dynamical dark energy theory,with the equation of state crossing the cosmological constant boundary w=-1.In this paper,we briefly review quintom cosmology,especially the quintom bounce.We will give three examples of a quintom bounce and one example of a cyclic universe with quintom matter.
