To the Editor:Unstable clinical conditions and complications make multiple laboratory tests and blood sampling inevitable in preterm infants,contributing to iatrogenic blood loss.Undoubtedly,iatrogenic blood loss is h...To the Editor:Unstable clinical conditions and complications make multiple laboratory tests and blood sampling inevitable in preterm infants,contributing to iatrogenic blood loss.Undoubtedly,iatrogenic blood loss is highly correlated with red blood cell transfusion(RBCT).A previous study on extremely low birth weight(BW)infants reported that the sampling blood loss was 30.0 mL/kg within the first week of life,leading to one or more RBCTs in 98%of patients.[1]RBCTs are increasingly reported to cause inflammatory responses and increase the incidence of preterm complications.Therefore,reducing iatrogenic blood loss could not only decrease the need for transfusions but also reduce the risk of neonatal mortality and morbidity.展开更多
基金supported by a grant from the National Natural Science Foundation of China(Nos.82271749 and 82171710).
文摘To the Editor:Unstable clinical conditions and complications make multiple laboratory tests and blood sampling inevitable in preterm infants,contributing to iatrogenic blood loss.Undoubtedly,iatrogenic blood loss is highly correlated with red blood cell transfusion(RBCT).A previous study on extremely low birth weight(BW)infants reported that the sampling blood loss was 30.0 mL/kg within the first week of life,leading to one or more RBCTs in 98%of patients.[1]RBCTs are increasingly reported to cause inflammatory responses and increase the incidence of preterm complications.Therefore,reducing iatrogenic blood loss could not only decrease the need for transfusions but also reduce the risk of neonatal mortality and morbidity.