The effects of different annealing processes on the phase precipitation behavior and corrosion properties of copper-bearing 430 ferritic stainless steel were systematically investigated.The shape,quantity and distribu...The effects of different annealing processes on the phase precipitation behavior and corrosion properties of copper-bearing 430 ferritic stainless steel were systematically investigated.The shape,quantity and distribution of copper-rich precipitates by different annealing processes were characterized by scanning electron microscopy,transmission electron microscopy,backscatter electron and backscatter diffraction.The pitting resistance behavior in simulated physiological saline envi-ronments(0.9 wt.%NaCl)was investigated using electrochemical workstation and X-ray photoelectron spectroscopy.The results showed that the copper-rich phase prepared by repeated rolling and annealing gradually changed from long needle-like to short thick rod-like and granular,whose distribution tended to be uniform and diffusive,and the number of copper-rich phases increased.After solution/antibacterial annealing process,the size and density of the copper-rich phase increase,resulting in a discontinuity of the passivation film on the stainless steel,which reduces the pitting resistance to some extent.The refinement mechanism revealed that pre-deformation brings about a modification in both precipitation mechanism and growth kinetics of epsilon copper.展开更多
Placentation and tumorigenesis have many common features.Human placentation builds a maternal-fetal connection,circumvents maternal immune rejection of the fetus,and utilizes mechanisms that support tumorigenesis,such...Placentation and tumorigenesis have many common features.Human placentation builds a maternal-fetal connection,circumvents maternal immune rejection of the fetus,and utilizes mechanisms that support tumorigenesis,such as proliferation,invasion,angiogenesis,and immune tolerance.Trophoblasts of the human placenta mimic the behavior of malignant cells,proliferating and invading the uterine decidua until reaching the myometrium and remodeling the spiral arteries that establish a new vascular system and escape the maternal immune response.These processes are under precise temporal and spatial regulation,and their dysregulation is associated with different pregnancy syndromes,including preeclampsia(PE),a pregnancy syndrome that is the leading cause of maternal and perinatal mortality and morbidity.At present,the precise mechanisms underlying the development of PE remain unclear.Here,we summarize and dissect the features between physiological placentation and pathological tumorigenesis to explore the pathogenesis of PE-which we believe to be the result of insufficient placentation,compared to the overaggression of tumorigenesis-to provide novel strategies to prevent and treat PE.展开更多
基金support of this work by the National Natural Science Foundation of China(51774226)the Major Program of Science and Technology in Shanxi Province(No.20191102006).
文摘The effects of different annealing processes on the phase precipitation behavior and corrosion properties of copper-bearing 430 ferritic stainless steel were systematically investigated.The shape,quantity and distribution of copper-rich precipitates by different annealing processes were characterized by scanning electron microscopy,transmission electron microscopy,backscatter electron and backscatter diffraction.The pitting resistance behavior in simulated physiological saline envi-ronments(0.9 wt.%NaCl)was investigated using electrochemical workstation and X-ray photoelectron spectroscopy.The results showed that the copper-rich phase prepared by repeated rolling and annealing gradually changed from long needle-like to short thick rod-like and granular,whose distribution tended to be uniform and diffusive,and the number of copper-rich phases increased.After solution/antibacterial annealing process,the size and density of the copper-rich phase increase,resulting in a discontinuity of the passivation film on the stainless steel,which reduces the pitting resistance to some extent.The refinement mechanism revealed that pre-deformation brings about a modification in both precipitation mechanism and growth kinetics of epsilon copper.
基金This study was supported by grants from the National Key R&D Program of China(2019YFA0802600 and 2017YFC1001403)NSFC(31871512 and 31671199)to CZSupport was also obtained by the Shanghai Commission of Science and Technology(17DZ2271100).
文摘Placentation and tumorigenesis have many common features.Human placentation builds a maternal-fetal connection,circumvents maternal immune rejection of the fetus,and utilizes mechanisms that support tumorigenesis,such as proliferation,invasion,angiogenesis,and immune tolerance.Trophoblasts of the human placenta mimic the behavior of malignant cells,proliferating and invading the uterine decidua until reaching the myometrium and remodeling the spiral arteries that establish a new vascular system and escape the maternal immune response.These processes are under precise temporal and spatial regulation,and their dysregulation is associated with different pregnancy syndromes,including preeclampsia(PE),a pregnancy syndrome that is the leading cause of maternal and perinatal mortality and morbidity.At present,the precise mechanisms underlying the development of PE remain unclear.Here,we summarize and dissect the features between physiological placentation and pathological tumorigenesis to explore the pathogenesis of PE-which we believe to be the result of insufficient placentation,compared to the overaggression of tumorigenesis-to provide novel strategies to prevent and treat PE.
