To address the current issues with the conventional slide gate system utilized in the steel teeming process,a unique electromagnetic induction controlled automated steel teeming(EICAST)technology has been developed.Co...To address the current issues with the conventional slide gate system utilized in the steel teeming process,a unique electromagnetic induction controlled automated steel teeming(EICAST)technology has been developed.Cooling means of spiral coil in this technology is directly related to its service life.Firstly,heat transfer processes of air cooling and spray cooling were compared and analyzed.Secondly,the impacts of water temperature,water flow rate and air flow rate were examined in order to maximize the spray cooling effect.To maintain coil temperature at a low value consistently throughout the entire thermal cycle process of the ladle,a combined cooling mode was finally employed.Numerical simulation was applied to examine the coil temperature variation with different cooling systems and characteristics.Before coil operation,spray cooling is said to be more effective.By controlling the water flow rate and air flow rate,the spray cooling effect is enhanced.However,water temperature has little or no impact when using spray cooling.Air cooling during the secondary refining process and spray cooling prior to coil operation are combined to further lower coil temperature.When the direction of the spray cooling is from bottom to top,the coil temperature is lowered below 165℃.A practical induction coil cooling plan was provided for the EICAST technology’s production process.展开更多
Steel teeming time is a very important parameter in the new slide gate system with electromagnetic induction （called electromagnetic steel teeming system）, and how to shorten this time is a key to realize applicatio...Steel teeming time is a very important parameter in the new slide gate system with electromagnetic induction （called electromagnetic steel teeming system）, and how to shorten this time is a key to realize application of the new system in continuous casting. The effects of power parameters, coil position, nozzle material and other factors on the steel teeming time were investigated by a self-designed electromagnetic steel teeming system in detail. The experimental results show that the relationship between power and steel teeming time is nonlinear. The coil position has great in- fluence on steel teeming time. And the upper nozzle with high permeability can reduce the teeming time. In addition, the steel teeming time becomes minimum when the size of the spherical cast iron particles is 2.0 ram. This research can provide technical references for the industrial application of the new electromagnetic steel teeming system.展开更多
Ambient temperature of induction coil is an important factor to influence the implementation of the electromagnetic induction-controlled automated steel-teeming(EICAST) technology. Meanwhile, it also affects the forma...Ambient temperature of induction coil is an important factor to influence the implementation of the electromagnetic induction-controlled automated steel-teeming(EICAST) technology. Meanwhile, it also affects the formation of Fe–C alloy blocking layer, which determines the length and installation position of induction coil. An experimental platform was designed to imitate actual working conditions in a ladle with the EICAST system. Ambient temperature of induction coil under high-temperature condition was measured to verify the accuracy of numerical result. After containing molten steel for 120 min and steel teeming for 40 min, the ambient temperature on the upper side of induction coil is 791 °C. In addition, the position of blocking layer in a 110 t ladle was measured by sand-collection and steel-pour methods, and the criterion temperatures of blocking layer in numerical simulation process were corrected. When the refining temperature is1600 °C and the containing time of molten steel is 120 min, the thickness of blocking layer is 130 mm, and the distance between the upper surface of blocking layer and the upper surface of nozzle brick is 154 mm. When the criterion temperatures are 919 °C and 428 °C, the numerical results can be used to confirm the position of blocking layer and the installation position of induction coil.展开更多
AIM:To observe the effects of salvianolic add B(SalB)on in vitro growth inhibition and apoptosis induction of retinoblastoma HXO-RB44 cells.METHODS:The effects of SalB on the HXO-RB44 cells proliferation in vitro were...AIM:To observe the effects of salvianolic add B(SalB)on in vitro growth inhibition and apoptosis induction of retinoblastoma HXO-RB44 cells.METHODS:The effects of SalB on the HXO-RB44 cells proliferation in vitro were observed by MTT colorimetric method.The morphological changes of apoptosis before and after the treatment of SalB were observed by Hoechst 33258 fluorescent staining method.Apoptosis rate and cell cycle changes of HXO-RB44 cells were detected by flow cytometer at 48 hours after treated by SalB.The expression changes of Caspase-3 protein in HXO-RB44 cells were detected by Western Blot.RESULTS:SalB significantly inhibited the growth of HXO-RB44 cells,while the inhibition was in a concentration-and time-dependent manner.The results of fluorescent staining method indicated that HXO-RB44 cells showed significant phenomenon of apoptosis including karyorrhexis,fragmentation and the formation of apoptotic bodies,etc.after 24,48 and 72 hours co-culturing of SalB and HXO-RB44 cells.The results of flow cytometer showed that the apoptosis rate and the proportion of cells in S phase were gradually increased at 48 hours and 72 hours after treated by different concentrations of SalB.Western Blot strip showed that the expression of Caspase-3 protein in HXO-RB44 cells was gradually increased with the increase of the concentration of SalB.CONCLUSION:SalB can significantly affect on HXO-RB44 cells growth inhibition and apoptosis induction which may be achieved through the up-regulation of Caspase-3 expression and the induction of cell cycle arrest.展开更多
基金supported by the Startup Foundation of Shenyang Agriculture University(No.X2023050)the Fundamental Research Funds for the Central Universities(No.N2209006)the National Natural Science Foundation of China(No.U22A20173).
文摘To address the current issues with the conventional slide gate system utilized in the steel teeming process,a unique electromagnetic induction controlled automated steel teeming(EICAST)technology has been developed.Cooling means of spiral coil in this technology is directly related to its service life.Firstly,heat transfer processes of air cooling and spray cooling were compared and analyzed.Secondly,the impacts of water temperature,water flow rate and air flow rate were examined in order to maximize the spray cooling effect.To maintain coil temperature at a low value consistently throughout the entire thermal cycle process of the ladle,a combined cooling mode was finally employed.Numerical simulation was applied to examine the coil temperature variation with different cooling systems and characteristics.Before coil operation,spray cooling is said to be more effective.By controlling the water flow rate and air flow rate,the spray cooling effect is enhanced.However,water temperature has little or no impact when using spray cooling.Air cooling during the secondary refining process and spray cooling prior to coil operation are combined to further lower coil temperature.When the direction of the spray cooling is from bottom to top,the coil temperature is lowered below 165℃.A practical induction coil cooling plan was provided for the EICAST technology’s production process.
基金Sponsored by Science and Techonlogy Program of Liaoning Province of China(2008221015)
文摘Steel teeming time is a very important parameter in the new slide gate system with electromagnetic induction （called electromagnetic steel teeming system）, and how to shorten this time is a key to realize application of the new system in continuous casting. The effects of power parameters, coil position, nozzle material and other factors on the steel teeming time were investigated by a self-designed electromagnetic steel teeming system in detail. The experimental results show that the relationship between power and steel teeming time is nonlinear. The coil position has great in- fluence on steel teeming time. And the upper nozzle with high permeability can reduce the teeming time. In addition, the steel teeming time becomes minimum when the size of the spherical cast iron particles is 2.0 ram. This research can provide technical references for the industrial application of the new electromagnetic steel teeming system.
基金financially supported by the National Natural Science Foundation of China (Grant No. U1560207)
文摘Ambient temperature of induction coil is an important factor to influence the implementation of the electromagnetic induction-controlled automated steel-teeming(EICAST) technology. Meanwhile, it also affects the formation of Fe–C alloy blocking layer, which determines the length and installation position of induction coil. An experimental platform was designed to imitate actual working conditions in a ladle with the EICAST system. Ambient temperature of induction coil under high-temperature condition was measured to verify the accuracy of numerical result. After containing molten steel for 120 min and steel teeming for 40 min, the ambient temperature on the upper side of induction coil is 791 °C. In addition, the position of blocking layer in a 110 t ladle was measured by sand-collection and steel-pour methods, and the criterion temperatures of blocking layer in numerical simulation process were corrected. When the refining temperature is1600 °C and the containing time of molten steel is 120 min, the thickness of blocking layer is 130 mm, and the distance between the upper surface of blocking layer and the upper surface of nozzle brick is 154 mm. When the criterion temperatures are 919 °C and 428 °C, the numerical results can be used to confirm the position of blocking layer and the installation position of induction coil.
基金National"Eleventh Five-year Plan"Science and Technology Support Project(No.2006BAI06 A15-3)
文摘AIM:To observe the effects of salvianolic add B(SalB)on in vitro growth inhibition and apoptosis induction of retinoblastoma HXO-RB44 cells.METHODS:The effects of SalB on the HXO-RB44 cells proliferation in vitro were observed by MTT colorimetric method.The morphological changes of apoptosis before and after the treatment of SalB were observed by Hoechst 33258 fluorescent staining method.Apoptosis rate and cell cycle changes of HXO-RB44 cells were detected by flow cytometer at 48 hours after treated by SalB.The expression changes of Caspase-3 protein in HXO-RB44 cells were detected by Western Blot.RESULTS:SalB significantly inhibited the growth of HXO-RB44 cells,while the inhibition was in a concentration-and time-dependent manner.The results of fluorescent staining method indicated that HXO-RB44 cells showed significant phenomenon of apoptosis including karyorrhexis,fragmentation and the formation of apoptotic bodies,etc.after 24,48 and 72 hours co-culturing of SalB and HXO-RB44 cells.The results of flow cytometer showed that the apoptosis rate and the proportion of cells in S phase were gradually increased at 48 hours and 72 hours after treated by different concentrations of SalB.Western Blot strip showed that the expression of Caspase-3 protein in HXO-RB44 cells was gradually increased with the increase of the concentration of SalB.CONCLUSION:SalB can significantly affect on HXO-RB44 cells growth inhibition and apoptosis induction which may be achieved through the up-regulation of Caspase-3 expression and the induction of cell cycle arrest.
