To the Editor:Measurement of nuchal translucency(NT)is a validated marker for aneuploidy,fetal abnormalities,and other pathologic conditions,[1] which makes it crucial to ensure the accuracy of NT measurement in clini...To the Editor:Measurement of nuchal translucency(NT)is a validated marker for aneuploidy,fetal abnormalities,and other pathologic conditions,[1] which makes it crucial to ensure the accuracy of NT measurement in clinical treatment.Ever since 2012,all the pregnant women visiting our hospital(The International Peace Maternity&Child Health Hospital Affliated to Shanghai Jiao Tong University School of Medicine,China)need to receive a routine first-trimester sonographic marker assessment.展开更多
The major mechanism for ring chromosome formation is thought to result from breakage and reunion at the breakpoints on the long and short arms of a chromosome.This fusion event can produce terminal arm inversions,dele...The major mechanism for ring chromosome formation is thought to result from breakage and reunion at the breakpoints on the long and short arms of a chromosome.This fusion event can produce terminal arm inversions,deletions,and duplications that determine the resulting phenotype.[1] Ring chromosome 13 is relatively uncommon,with an estimated incidence of 1/58,000 live births.展开更多
Twin pregnancies have increased significantly over recent decades,mainly due to the growing rate of such pregnancies that have been achieved via assisted reproductive techniques.Twin pregnancies are associated with hi...Twin pregnancies have increased significantly over recent decades,mainly due to the growing rate of such pregnancies that have been achieved via assisted reproductive techniques.Twin pregnancies are associated with high infant morbidity and mortality.Maternal obesity has been found to be significantly related to an increased risk of pre-eclampsia and other adverse outcomes.Maternal weight gains during pregnancy may have important implications for maternal and fetus health.Women with excessive gestational weight gains(GWG)are more likely to increase their risk of gestational diabetes mellitus(GDM),macrosomia,preterm birth,and fetal growth restriction.As with singletons,GDM is also expected to be more frequent in pre-gravid obese mothers of twins.111 Although there are some guides for twin pregnancies,few researches are focused on the systematic management of twin pregnancies.展开更多
基金the Interdisciplinary Program of Shanghai Jiao Tong University(No.YG2017MS37)the National Natural Science Foundation of China(No.81971401)+3 种基金the Western Medicine Guide Project of Shanghai Science and Technology Commission(No.19411960900)the Project of Translational Medicine Cross-research Fund,Shanghai Jiao Tong University(No.ZH2018QNB14)Chinese Academy of Medical Sciences Research Unit(No.2019RU056),Shanghai Jiao Tong University,CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2019-I2M-5-064)Shanghai Municipal Key Clinical Specialty,Shanghai,China.
文摘To the Editor:Measurement of nuchal translucency(NT)is a validated marker for aneuploidy,fetal abnormalities,and other pathologic conditions,[1] which makes it crucial to ensure the accuracy of NT measurement in clinical treatment.Ever since 2012,all the pregnant women visiting our hospital(The International Peace Maternity&Child Health Hospital Affliated to Shanghai Jiao Tong University School of Medicine,China)need to receive a routine first-trimester sonographic marker assessment.
文摘The major mechanism for ring chromosome formation is thought to result from breakage and reunion at the breakpoints on the long and short arms of a chromosome.This fusion event can produce terminal arm inversions,deletions,and duplications that determine the resulting phenotype.[1] Ring chromosome 13 is relatively uncommon,with an estimated incidence of 1/58,000 live births.
基金This work was supported by the National Natural Science Foundation of China(No.81971401)Chinese Academy of Medical Sciences Research Unit(No.2019RU056)+2 种基金CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-064)the Western Medicine Guide Project of Shanghai Science and Technology Commission(No.19411960900)the Project of Translational Medicine Cross-research Fund,Shanghai JiaoTong University(No.ZH2018QNB14).
文摘Twin pregnancies have increased significantly over recent decades,mainly due to the growing rate of such pregnancies that have been achieved via assisted reproductive techniques.Twin pregnancies are associated with high infant morbidity and mortality.Maternal obesity has been found to be significantly related to an increased risk of pre-eclampsia and other adverse outcomes.Maternal weight gains during pregnancy may have important implications for maternal and fetus health.Women with excessive gestational weight gains(GWG)are more likely to increase their risk of gestational diabetes mellitus(GDM),macrosomia,preterm birth,and fetal growth restriction.As with singletons,GDM is also expected to be more frequent in pre-gravid obese mothers of twins.111 Although there are some guides for twin pregnancies,few researches are focused on the systematic management of twin pregnancies.
