Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gan...Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gangrene.Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease.The present case involved a 62-year-old male patient with poorly controlled diabetes,who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed.However,the procedure was unsuccessful.This case was characterized by rapid disease progression,widespread wound involvement,and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.Our team performed early,extensive surgical debridement and,based on the results of antimicrobial susceptibility testing,initiated combination antibiotic therapy.The patient’s condition improved significantly after these interventions.However,the treatment was ultimately discontinued by the patient’s family for personal reasons,and follow-up care was declined.展开更多
Graphene is a two-dimensional nanomaterial with huge surface area,high carrier mobility and high mechanical strength.Because of its great potential in nanotechnology and environmental protection,it has attracted much ...Graphene is a two-dimensional nanomaterial with huge surface area,high carrier mobility and high mechanical strength.Because of its great potential in nanotechnology and environmental protection,it has attracted much attention in environmental and energy fields since its discovery in 2004.Although graphene is a star material,many reviews have introduced its use in terms of energy,the research progress in the field of environment,especially water pollution control,has been rarely reported.Here,we review exhaustively the research progress of graphene-based materials in environmental pollution remediation in the past ten years.Firstly,the advantages and classification of graphene were introduced.Secondly,the research progress and main achievements of graphene and its composites in the fields of photocatalytic degradation,pollutant adsorption and water treatment were emphatically described,and the mechanism of action in the above fields was summarized.Finally,we discuss the problems existing in the preparation and summarize the application of graphene in the environment.展开更多
基金supported by the Collaborative Innovation Center of China’s Ministry of Education(grant no.2020-39)Constructive Project of Innovative Talent Platform for Precise Repair of Wounds(grant no.2021-3)+1 种基金Scientific Research and Talent Training Fund of Kweichow Moutai Hospital(grant no.2022-13)Shanghai Wang Zhengguo Trauma Medicine Development Foundation(grant no.SZYZ-TR-05).
文摘Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gangrene.Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease.The present case involved a 62-year-old male patient with poorly controlled diabetes,who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed.However,the procedure was unsuccessful.This case was characterized by rapid disease progression,widespread wound involvement,and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.Our team performed early,extensive surgical debridement and,based on the results of antimicrobial susceptibility testing,initiated combination antibiotic therapy.The patient’s condition improved significantly after these interventions.However,the treatment was ultimately discontinued by the patient’s family for personal reasons,and follow-up care was declined.
基金supported by the State Key Research Development Program of China(No.2016YFA0204200)National Natural Science Foundation of China(Nos.21822603,21811540394,5171101651,21677048,21773062,21577036)+1 种基金Shanghai Pujiang Program(No.17PJD011)the Fundamental Research Funds for the Central Universities(No.22A201514021)。
文摘Graphene is a two-dimensional nanomaterial with huge surface area,high carrier mobility and high mechanical strength.Because of its great potential in nanotechnology and environmental protection,it has attracted much attention in environmental and energy fields since its discovery in 2004.Although graphene is a star material,many reviews have introduced its use in terms of energy,the research progress in the field of environment,especially water pollution control,has been rarely reported.Here,we review exhaustively the research progress of graphene-based materials in environmental pollution remediation in the past ten years.Firstly,the advantages and classification of graphene were introduced.Secondly,the research progress and main achievements of graphene and its composites in the fields of photocatalytic degradation,pollutant adsorption and water treatment were emphatically described,and the mechanism of action in the above fields was summarized.Finally,we discuss the problems existing in the preparation and summarize the application of graphene in the environment.
