期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
母猪饲喂关键营养技术 被引量:3
1
作者 丁小玲 苗文萍 +2 位作者 张琳琨 刘国桢 张宇昕 《猪业科学》 2021年第5期42-45,共4页
母猪的生产性能影响整个猪场的效益,营养调控是改善母猪生产性能的重要途径。文章结合国内外母猪营养研究的最新报道,概述了母猪后备期、妊娠期和泌乳期的关键营养技术,为养猪生产中的营养调控提供参考。
关键词 母猪 营养技术 生产性能 阶段营养
在线阅读 下载PDF
免疫治疗在胃癌中的应用研究进展 被引量:10
2
作者 熊德君 丁晓凌 周晓荣 《中国肿瘤临床》 CAS CSCD 北大核心 2024年第7期359-365,共7页
胃癌是全球最常见的恶性肿瘤之一,由于胃癌筛查率低和早期症状轻微,多数患者在晚期才被确诊,影响预后。近年来,随着研究深入,胃癌的免疫治疗取得显著进展,尤其对不可切除和转移性病例效果显著,使其成为继手术、化疗、放疗和靶向治疗后... 胃癌是全球最常见的恶性肿瘤之一,由于胃癌筛查率低和早期症状轻微,多数患者在晚期才被确诊,影响预后。近年来,随着研究深入,胃癌的免疫治疗取得显著进展,尤其对不可切除和转移性病例效果显著,使其成为继手术、化疗、放疗和靶向治疗后的有效治疗方法。免疫治疗通过人为调控免疫系统生效,包括过继细胞疗法、免疫检查点抑制剂和肿瘤疫苗等。目前,免疫治疗虽然前景广阔,但在临床应用中仍面临诸多挑战和问题。本文就胃癌免疫治疗的临床应用以及存在的问题进行综述。 展开更多
关键词 胃癌 免疫治疗 过继细胞疗法 免疫检查点抑制剂 肿瘤疫苗
暂未订购
间充质干细胞及其外泌体对肿瘤影响的研究进展 被引量:4
3
作者 崔舒悦 汤帅 +1 位作者 丁晓玲 丁刚 《中国肺癌杂志》 CAS CSCD 北大核心 2022年第5期351-357,共7页
在我国,无论城市还是农村,恶性肿瘤都是我国居民死亡的主要原因。间充质干细胞(mesenchymal stem cells,MSCs)具有多向分化潜能、自我更新能力和良好的免疫调节特性。而外泌体作为MSCs旁分泌的重要物质,在肿瘤微环境中介导细胞间的信息... 在我国,无论城市还是农村,恶性肿瘤都是我国居民死亡的主要原因。间充质干细胞(mesenchymal stem cells,MSCs)具有多向分化潜能、自我更新能力和良好的免疫调节特性。而外泌体作为MSCs旁分泌的重要物质,在肿瘤微环境中介导细胞间的信息交流与传递,影响肿瘤的发生发展。有研究报道了MSCs及其来源的外泌体对肿瘤的影响具有相互矛盾的发现,一方面MSCs及其外泌体具有肿瘤趋向性,能够靶向特定部位抑制肿瘤生长;另一方面也有证据表明MSCs具有致瘤性,作为肿瘤微环境的一部分影响肿瘤的生长和迁移。本文将综述MSCs及其外泌体与肿瘤发生发展的关系以及MSCs及其外泌体如何在肿瘤发生发展中扮演不同角色,以期为肿瘤的诊断、预后和精准治疗提供有益的帮助。 展开更多
关键词 间充质干细胞 外泌体 肿瘤 癌症
暂未订购
Integrated Active Suspension and Anti-Lock Braking Control for Four-Wheel-Independent-Drive Electric Vehicles 被引量:1
4
作者 Ze Zhao Lei Zhang +3 位作者 xiaoling ding Zhiqiang Zhang Shaohua Li Liang Gu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期87-98,共12页
This paper presents an integrated control scheme for enhancing the ride comfort and handling performance of a four-wheel-independent-drive electric vehicle through the coordination of active suspension system(ASS)and ... This paper presents an integrated control scheme for enhancing the ride comfort and handling performance of a four-wheel-independent-drive electric vehicle through the coordination of active suspension system(ASS)and anti-lock braking system(ABS).First,a longitudinal-vertical coupled vehicle dynamics model is established by integrating a road input model.Then the coupling mechanisms between longitudinal and vertical vehicle dynamics are analyzed.An ASS-ABS integrated control system is proposed,utilizing an H∞controller for ASS to optimize load transfer effect and a neural network sliding mode control for ABS implementation.Finally,the effectiveness of the proposed control scheme is evaluated through comprehensive tests conducted on a hardware-in-loop(HIL)test platform.The HIL test results demonstrate that the proposed control scheme can significantly improve the braking performance and ride comfort compared to conventional ABS control methods. 展开更多
关键词 Four-wheel-independent-drive electric vehicles Active suspension system(ASS) Anti-lock braking system(ABS) Vertical-longitudinal vehicle dynamics
在线阅读 下载PDF
Undernutrition disrupts jejunal and ileal microbiota and epithelial tissue homeostasis in a pregnant sheep model
5
作者 Weibin Wu Muhammad Faheem Akhtar +6 位作者 Jiahong Geng Huizhen Lu Muhammad Ajwad Rahim Jianbo Cheng xiaoling ding Shengyong Mao Yanfeng Xue 《Animal Nutrition》 2025年第1期263-276,共14页
Nutrition consistently affects microbe-host interactions in the gastrointestinal tract. This study aimed to unravel how undernutrition reshapes the microbial composition and the homeostasis of epithelium in the jejunu... Nutrition consistently affects microbe-host interactions in the gastrointestinal tract. This study aimed to unravel how undernutrition reshapes the microbial composition and the homeostasis of epithelium in the jejunum and ileum. Sixteen late-gestation Hu-sheep were randomly assigned to the control group(n=8, 100% ad libitum feeding levels) or the undernutrition group(n=8, which received 30% ad libitum feeding levels). After 15-d treatment, all ewes were slaughtered, and jejunal and ileal digesta and epithelium samples were collected for 16S rRNA gene sequencing and transcriptome sequencing,respectively. Results indicated that undernutrition decreased the jejunal and ileal tissue weights(P=0.005 and P=0.022) and the levels of volatile fatty acids(P=0.019 and P=0.007) and microbial protein levels(P=0.019 and P=0.031) in jejunal and ileal digesta. The relative abundance of acetate producing microbiota, including Clostridia UCG-014 norank, Ruminococcus, [Ruminococcus] gauvreauii, and Lachnospiraceae_Blautia, were significantly reduced(P<0.05) in the jejunum and ileum. Undernutrition up-regulated(P<0.05) the expression of genes involved in amino acid synthesis and fatty acid oxidation,but down-regulated(P<0.05) the expression of genes associated with amino acid degradation, fatty acid synthesis, and extracellular structures in jejunal and ileal epithelium. In the jejunal epithelium, genes associated with extracellular matrix-receptor interactions, cell growth, and immune response were down-regulated(P<0.05) upon undernutrition. Taken together, undernutrition changed the microbial community in the jejunum and ileum, which altered the fermentation mode and the production of volatile fatty acids and microbial protein. These affected the energy and protein system in the epithelium and reprogrammed substance metabolism and extracellular structures, which probably further influenced cell growth and immune response. These insights provide a foundation for completely clarifying the crosstalk between small intestinal microbiota and the host. 展开更多
关键词 UNDERNUTRITION MICROBIOTA Epithelial metabolism Immune response
原文传递
Enhanced photocatalytic hydrogen evolution along with byproducts suppressing over Z-scheme CdxZn1-xS/Au/g-C3N4 photocatalysts under visible light 被引量:12
6
作者 He Zhao xiaoling ding +2 位作者 Bing Zhang Yingxuan Li Chuanyi Wang 《Science Bulletin》 SCIE EI CAS CSCD 2017年第9期602-609,共8页
Inspired by natural photosynthesis, a new series of Z-scheme Cd_xZn_(1-x)S/Au/g-C_3N_4 photocatalysts were synthesized via depositing Au particles on g-C_3N_4, followed by anchoring CdxZn_(1-x)S solid solution on the ... Inspired by natural photosynthesis, a new series of Z-scheme Cd_xZn_(1-x)S/Au/g-C_3N_4 photocatalysts were synthesized via depositing Au particles on g-C_3N_4, followed by anchoring CdxZn_(1-x)S solid solution on the pre-formed Au/g-C_3N_4 for photocatalytic hydrogen evolution. Their structure, morphology and optical property were investigated in detail. Photocatalytic activities of the developed photocatalysts for water splitting were evaluated under visible-light irradiation(k > 420 nm) using glucose as electron donor.The highest hydrogen evolution rate of 123 lmol g^(-1)h^(-1)is achieved by Cd_(0.8Z)n_(0.2)S/Au/g-C_3N_4, which is 52.2 and 8.63 times higher than that of Au/g-C_3N_4 and Cd S/Au/g-C_3N_4, respectively. The results of photoluminescence spectra, photoelectrochemical and time-resolved photoluminescence spectra indicate that the improved photocatalytic activities for Cd_xZn_(1-x)S/Au/g-C_3N_4 are due to the efficient separation of photogenerated carriers. In addition, it is noteworthy that the undesired byproducts CO and CO_2 are greatly reduced by introducing CdxZn_(1-x)S over Au/g-C_3N_4 surface. In the photocatalytic process, gluconic acid originated from the reaction of photogenerated hydroxyl radical with glucose plays a vital role on suppressing the formation of the gas byproducts. The present work will provide a new strategy to design Z-scheme photocatalysts with enhanced efficiency for water splitting along with suppressing the byproducts. 展开更多
关键词 Hydrogen evolution CdxZn1-xS/Au/g-C3N4 BYPRODUCTS Z-scheme Visible light
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部