Neoplasms of the vermiform appendix represent 1% of all gastrointestinal tumors, with epithelial and neuroendocrine histological subtypes being the most frequent. When two or more neoplasms with different components o...Neoplasms of the vermiform appendix represent 1% of all gastrointestinal tumors, with epithelial and neuroendocrine histological subtypes being the most frequent. When two or more neoplasms with different components originate synchronically in the appendix with clear margin between them, it is called a collision tumor, with exceptional cases being reported in literature. The purpose is to present two new cases of collision tumors of the appendix and perform a review of the published literature. Two cases of an 82-year-old female and a 41-year-old male with collision tumors of the vermiform appendix are presented, with clinical presentation, radiological evaluation and surgical treatment exposed. Our results are compared with other published reports. In accordance with the other reported cases, both patients presented with low-grade appendiceal mucinous neoplasm (LAMN). Female patient with synchronous goblet cell carcinoma managed with a completion right colectomy and Hyperthermic intraperitoneal chemotherapy (HIPEC) and the other patient with well-differentiated neuroendocrine (NET) tumor managed with laparoscopic appendectomy without adjuvant treatment. Since very few cases have been reported, no diagnostic and therapeutic consensus and guidelines exist up to date. We agree that local, regional, and systemic therapies should be chosen according to the tumor that represents the worst prognosis.展开更多
The influence of Ce-Co alloy addition and sintering holding time on permanent magnetic properties and micro structure of nanocrystalline Nd-Fe-B bulk alloy were investigated.The coercivity of Nd-Fe-B bulk alloy can be...The influence of Ce-Co alloy addition and sintering holding time on permanent magnetic properties and micro structure of nanocrystalline Nd-Fe-B bulk alloy were investigated.The coercivity of Nd-Fe-B bulk alloy can be enhanced greatly by more than 100% after adding Ce-Co powders.However,when the concentration of Ce-Co is up to 30 wt%,the density of the magnet can reach the maximum value of 7.58 g/cm^(3),but the coercivity does not increase significantly.On the other hand,with the increase of holding time to 10 min,the density and coercivity of magnets increase gradually,reaching up to 7.55 g/cm^(3) and 1134.3 kA/m,respectively.After the addition of Ce-Co alloy,Ce-Co may easily diffuse into the Nd-Fe-B matrix during hot-pressing and under the high pressure and temperature,thus increasing the content of grain boundary phase and the pinning effect of grain boundary,which leads to the increase of coercivity.The extension of the hot-pressing holding time may be more conducive to the diffusion of CeCo into the Nd-Fe-B matrix.In addition,the effect of Ce-Co addition on the magnetic properties of Nd-FeB with different content of rare earth was also studied.The addition of Ce-Co can effectively increase the coercivity of nanocomposite Nd_(2)Fe_(14)B/α-Fe magnets.The addition of Nb to the parent alloy can further improve the coercivity.For Nd_(11)Fe_(81.5)Nb_(1)Ga_(0.5)B_(6) alloy with 10 wt% Ce-Co addition,the coercivity can increase from 740.28 to 1098.48 kA/m.展开更多
Purpose:Research dynamics have long been a research interest.It is a macro perspective tool for discovering temporal research trends of a certain discipline or subject.A micro perspective of research dynamics,however,...Purpose:Research dynamics have long been a research interest.It is a macro perspective tool for discovering temporal research trends of a certain discipline or subject.A micro perspective of research dynamics,however,concerning a single researcher or a highly cited paper in terms of their citations and“citations of citations”(forward chaining)remains unexplored.Design/methodology/approach:In this paper,we use a cross-collection topic model to reveal the research dynamics of topic disappearance topic inheritance,and topic innovation in each generation of forward chaining.Findings:For highly cited work,scientific influence exists in indirect citations.Topic modeling can reveal how long this influence exists in forward chaining,as well as its influence.Research limitations:This paper measures scientific influence and indirect scientific influence only if the relevant words or phrases are borrowed or used in direct or indirect citations.Paraphrasing or semantically similar concept may be neglected in this research.Practical implications:This paper demonstrates that a scientific influence exists in indirect citations through its analysis of forward chaining.This can serve as an inspiration on how to adequately evaluate research influence.Originality:The main contributions of this paper are the following three aspects.First,besides research dynamics of topic inheritance and topic innovation,we model topic disappearance by using a cross-collection topic model.Second,we explore the length and character of the research impact through“citations of citations”content analysis.Finally,we analyze the research dynamics of artificial intelligence researcher Geoffrey Hinton’s publications and the topic dynamics of forward chaining.展开更多
In this note, the authors prove that the commutator Tb, generated by θ-type Calderon-Zygmund operator T and a Lipschitz function b is bounded from LP（R^n） intoLip（β_n/p）（R^n） and also maps from Ln/β （R^n） i...In this note, the authors prove that the commutator Tb, generated by θ-type Calderon-Zygmund operator T and a Lipschitz function b is bounded from LP（R^n） intoLip（β_n/p）（R^n） and also maps from Ln/β （R^n） into BMO（R^n）.展开更多
Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in ...Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in Fuzhou in the Fujian Province of southeast China, resulting in the death of 51 parrots. In this study, the disease was diagnosed and the pathogen was identified by PCR and whole genome sequencing. A distinct BFDV strain was identified and named as the FZ strain.This BFDV strain caused severe disease symptoms and pathological changes characteristic of typical PBFD in parrots, for example, loss of feathers and deformities of the beak and claws, and severe pathological changes in multiple organs of the infected birds. Phylogenetic analysis showed that the FZ strain was more closely related to the strain circulating in New Caledonia than the strains previously reported in China. Nucleotide homology between the FZ strain and other 43 strains of BFDV ranged from 80.0% to 92.0%. Blind passage experiment showed that this strain had limited replication capability in SPF Chicken Embryos and DF-1 Cells. Furthermore, the capsid(Cap) gene of this FZ strain was cloned into the p GEX-4 T-1 expression vector to prepare the polyclonal anti-Cap antibody. Western blotting analysis using the anti-Cap antibody further confirmed that the diseased parrots were infected with BFDV. In this study, a PBFD and its pathogen was identified for the first time in Fujian Province of China, suggesting that future surveillance of BFDV should be performed.展开更多
Purpose:To address the“anomalies”that occur when scientific breakthroughs emerge,this study focuses on identifying early signs and nascent stages of breakthrough innovations from the perspective of outliers,aiming t...Purpose:To address the“anomalies”that occur when scientific breakthroughs emerge,this study focuses on identifying early signs and nascent stages of breakthrough innovations from the perspective of outliers,aiming to achieve early identification of scientific breakthroughs in papers.Design/methodology/approach:This study utilizes semantic technology to extract research entities from the titles and abstracts of papers to represent each paper’s research content.Outlier detection methods are then employed to measure and analyze the anomalies in breakthrough papers during their early stages.The development and evolution process are traced using literature time tags.Finally,a case study is conducted using the key publications of the 2021 Nobel Prize laureates in Physiology or Medicine.Findings:Through manual analysis of all identified outlier papers,the effectiveness of the proposed method for early identifying potential scientific breakthroughs is verified.Research limitations:The study’s applicability has only been empirically tested in the biomedical field.More data from various fields are needed to validate the robustness and generalizability of the method.Practical implications:This study provides a valuable supplement to current methods for early identification of scientific breakthroughs,effectively supporting technological intelligence decision-making and services.Originality/value:The study introduces a novel approach to early identification of scientific breakthroughs by leveraging outlier analysis of research entities,offering a more sensitive,precise,and fine-grained alternative method compared to traditional citation-based evaluations,which enhances the ability to identify nascent breakthrough innovations.展开更多
Background: The mortality rate of colorectal cancer in China is on the rise, which has exceeded the global average rate, thus making the care of colorectal cancer widely concerned. As a comprehensive nursing model, th...Background: The mortality rate of colorectal cancer in China is on the rise, which has exceeded the global average rate, thus making the care of colorectal cancer widely concerned. As a comprehensive nursing model, the patient navigation model has shown its effectiveness in improving the quality of life among patients with chronic diseases and reducing the shortage of current healthcare resources in some area. This study aims to identify the current status and dilemma of the patient navigation model applied in colorectal cancer care in China. Methods: Bibliometric method was used to analyze published articles regarding the application of patient navigation model in colorectal cancer care retrieved from the Web of Science database. Statistics were presented using visualization method processed by the Bibliographic Items Co-occurrence Matrix Builder (BICOMB) software. Results: 124 articles, from 2006 to 2018, covering 14 countries, involving 931 researchers, 356 institutions and 60 publications were obtained;American research papers are the largest components of the aforementioned articles;only one of them is written by Chinese authors. The 3 leading institutions in this domain are University OF Rochester, Ohio State University, Icahn School of Medicine at Mount Sinai, yet the distribution of authors is relatively decentralized. “Cancer” is the main journal that publishes the researches in this domain. Research hotspots are on “cancer prevention and screening”, “health disparities”, “economic evaluation”, “patient navigators”, and “ethnicity”. Conclusion: In China, the research on the patient navigation is still in its infancy. Therefore, the Chinese government should provide more endorsement to this particular area and encourage the cooperation with other countries. China, having a long way to go, should further explore patient navigation on colorectal cancer care and establish a model that matches its cultural backgrounds.展开更多
Information on the Arctic sea ice climate indicators is crucial to business strategic planning and climate monitoring.Data on the evolvement of the Arctic sea ice and decadal trends of phenology factors during melt se...Information on the Arctic sea ice climate indicators is crucial to business strategic planning and climate monitoring.Data on the evolvement of the Arctic sea ice and decadal trends of phenology factors during melt season are necessary for climate prediction under global warming.Previous studies on Arctic sea ice phenology did not involve melt ponds that dramatically lower the ice surface albedo and tremendously affect the process of sea ice surface melt.Temporal means and trends of the Arctic sea ice phenology from 1982 to 2017 were examined based on satellite-derived sea ice concentration and albedo measurements.Moreover,the timing of ice ponding and two periods corresponding to it were newly proposed as key stages in the melt season.Therefore,four timings,i.e.,date of snow and ice surface melt onset(MO),date of pond onset(PO),date of sea ice opening(DOO),and date of sea ice retreat(DOR);and three durations,i.e.,melt pond formation period(MPFP,i.e.,MO–PO),melt pond extension period(MPEP,i.e.,PO–DOR),and seasonal loss of ice period(SLIP,i.e.,DOO–DOR),were used.PO ranged from late April in the peripheral seas to late June in the central Arctic Ocean in Bootstrap results,whereas the pan-Arctic was observed nearly 4 days later in NASA Team results.Significant negative trends were presented in the MPEP in the Hudson Bay,the Baffin Bay,the Greenland Sea,the Kara and Barents seas in both results,indicating that the Arctic sea ice undergoes a quick transition from ice to open water,thereby extending the melt season year to year.The high correlation coefficient between MO and PO,MPFP illustrated that MO predominates the process of pond formation.展开更多
A novel tetra-nuclear Tb-organic network,named as [Tb_(4)(2-pyia)_(6)(HAc)_(0.5)(2,2'-bipy)(H_(2)O)_(4.5)]·2,2'-bipy·H_(2)O(1),was synthesized hydrothermally based on 5-(pyridin-2-ylmethoxy) isophtha...A novel tetra-nuclear Tb-organic network,named as [Tb_(4)(2-pyia)_(6)(HAc)_(0.5)(2,2'-bipy)(H_(2)O)_(4.5)]·2,2'-bipy·H_(2)O(1),was synthesized hydrothermally based on 5-(pyridin-2-ylmethoxy) isophthalic acid(H_(2)pyia) and 2,2'-bipyridine(2,2'-bipy) ligands,and characterized by single crystal X-ray diffraction,thermogravimetric(TG) analyses,powder X-ray diffraction(PXRD) and infrared(IR) technology.1 possesses a two-dimensional network based on the tetra-nuclear inorganic building units,and the π-πstacking interactions between the pyia^(2-) ligands and the vip 2,2'-bipy molecules play an important role in the forming of 3D supramolecular structure.1 exhibits excellent fluorescent sensing performance for Fe^(3+)(1.26×10^(-8) mol/L),Cr_(2)O_(7)^(2-)(8.1×10^(-7) mol/L),2,4,6-trinitrophenol(TNP)(2.71×10^(-8) mol/L)and tetracycline(TCT)(2.76×10^(-7) mol/L) in aqueous solution with lower detection concentrations.The sensing mechanisms of 1 were investigated by density functional theory(DFT) calculations,ultraviolet-visible(UV-Vis) diffuse reflectance spectroscopy,PXRD and fluorescent lifetime analyses.The activated product of 1 was prepared by heating at 255℃ under constant pressure and used to photo-catalytically degrade TCT.Both 1 and the activated one have good photocatalytic degradation performance for TCT with degradation rates of 84.29% and 96.07%,respectively.The photocatalytic mechanisms were discovered by UV-Vis diffuse reflectance spectroscopy and radical trap experiments.The Tb-organic framework might be an excellent multifunctional fluorescent sensor and a good photocatalytic agent for TCT degradation in the future.展开更多
In this paper, the author proves that Multiplier operator is bounded on BMO（Rn）, LMO（Rn） and CBMOPp,λ（Rn） respectively if some concellation conditions are satisfied.
In this note, the author prove that maximal Bocher-Riesz commutator Bδ,＊^b generated by operator Bδ,＊ and function b∈ BMO（ω） is a bounded operator from L^p（μ） into L^p（ν）, where w∈ （μν^- 1）^1/p,μ...In this note, the author prove that maximal Bocher-Riesz commutator Bδ,＊^b generated by operator Bδ,＊ and function b∈ BMO（ω） is a bounded operator from L^p（μ） into L^p（ν）, where w∈ （μν^- 1）^1/p,μ,v ∈ Ap for 1 〈 p 〈 ∞. The proof relies heavily on the pointwise estimates for the sharp maximal function of the commutator Bδ,＊^b.展开更多
This note investigates the global regularity of 3D liquid crystal equations in terms of the vertical derivative of uh.More precisely,we prove that if the vertical derivative of the horizontal velocity component uh sat...This note investigates the global regularity of 3D liquid crystal equations in terms of the vertical derivative of uh.More precisely,we prove that if the vertical derivative of the horizontal velocity component uh satisfiesδ_(3uh)∈L^(p)(0,T;R^(3))with 2/p+3/q≤3/2,2≤p≤∞,then the local strong solution(u,d)can be smoothly extended beyond t=T.展开更多
In order to provide the technological support for further implementing measures of reducing chemical pesticide to control plant diseases,the research progress on non-chemical pesticide measures to control plant diseas...In order to provide the technological support for further implementing measures of reducing chemical pesticide to control plant diseases,the research progress on non-chemical pesticide measures to control plant diseases are reviewed from the aspects of agricultural control,botanical pesticide control and microbial pesticide control,and the development prospects are proposed,including accelerating innovative research on botani-cal pesticide control such as Chinese herb extracts,and screening microbial pesticides from valuable bio-control bacteria or plant endophyte metabolites for commercial production and utilization.展开更多
The aim of this article is to review our recent work on nonlocal dynamics of non-Gaussian systems arising in a gene regulatory network.We have used the mean exit time,escape probability and maximal likely trajectory t...The aim of this article is to review our recent work on nonlocal dynamics of non-Gaussian systems arising in a gene regulatory network.We have used the mean exit time,escape probability and maximal likely trajectory to quantify dynamical behaviors of a stochastic diferential system with non-Gaussianα-stable Lévy motions,to examine how the nonGaussianity index and noise intensity afect the gene transcription processes.展开更多
Seasonal distribution of mono-modal, monsoonal rainfall across the semi-arid ecotone of sub-Saharan of West Africa is highly variable and unpredictable. The ever-present risk of drought and crop failure in this enviro...Seasonal distribution of mono-modal, monsoonal rainfall across the semi-arid ecotone of sub-Saharan of West Africa is highly variable and unpredictable. The ever-present risk of drought and crop failure in this environment often results in food shortages that are met by emergency food aid. Humanitarian assistance planners would be better prepared for such interventions in a timely manner if they have reliable indicators that forewarn the impending failure of the rains. A good indicator would be a characteristic of the seasonal rainfall distribution that can be shown to be reasonably invariant over time and space. The objective of this study is to investigate whether such invariance existed for the seasonal median date (meaning the date when 50% of the seasonal total occurs). Such invariance is expected since the sun’s cyclic declination forces the advance and retreat of the Inter-tropical Front over West Africa. We examined the statistical properties of the seasonal median date for 1349 station-years of rainfall records for 30 rainfall stations in Burkina Faso and Niger with coordinates ranging from 9.88° to 18.5° north latitude and -4.77° to 13.2° longitude. The results showed that the median date was quite narrowly distributed over years with rather weak dependence on geographical coordinates. It can therefore be used as a reasonable ex-ante indicator of the success or failure of the rains as the rainy season progress.展开更多
This study was designed to explore the prevalence of fibrovascular proliferation not regressed in zone Ⅱ stage 3 retinopathy of prematurity(ROP)after initial intravitreal ranibizumab(IVR)injections and to explore the...This study was designed to explore the prevalence of fibrovascular proliferation not regressed in zone Ⅱ stage 3 retinopathy of prematurity(ROP)after initial intravitreal ranibizumab(IVR)injections and to explore the possible influence factors.Fifty-seven patients(108 eyes)with ROP who underwent intravitreal injection of ranibizumab between January 2013 and July 2014 participated in the retrospective study.Based on regress of fibrovascular tissue or not after initial injections of ranibizumab,eligible eyes were divided into two groups.Data was collected and analyzed with SPSS 16.0.In the study,108 eyes of 57 patients(18 females,39 males)underwent initial intravitreal injection.The mean birth weight was 1,440.0±357.7 g and the mean gestational age was 30.5±2.0 weeks.Eight of 57(14.0%)patients showed unfavorable fibrovascular proliferation after initial ranibizumab treatment within 2 weeks.Among them,11 eyes were controlled by further laser treatment and 3 eyes underwent vitrectomy.The difference of occurrence rate in hemorrhage between the two groups was significant(P<0.030),and the unfavorable group required more laser treatment(P<0.001).The incidence of unfavorable fibrovascular proliferation was relatively high,and intraocular hemorrhage was possibly associated with the progress in zone Ⅱ stage 3 ROP after initial IVR injection.展开更多
With the rapid development of the society,water contamination events cause great loss if the accidents happen in the water supply system.A large number of sensor nodes of water quality are deployed in the water supply...With the rapid development of the society,water contamination events cause great loss if the accidents happen in the water supply system.A large number of sensor nodes of water quality are deployed in the water supply network to detect and warn the contamination events to prevent pollution from speading.If all of sensor nodes detect and transmit the water quality data when the contamination occurs,it results in the heavy communication overhead.To reduce the communication overhead,the Connected Dominated Set construction algorithm-Rule K,is adopted to select a part fo sensor nodes.Moreover,in order to improve the detection accuracy,a Spatial-Temporal Abnormal Event Detection Algorithm with Multivariate water quality data(M-STAEDA)was proposed.In M-STAEDA,first,Back Propagation neural network models are adopted to analyze the multiple water quality parameters and calculate the possible outliers.Then,M-STAEDA algorithm determines the potential contamination events through Bayesian sequential analysis to estimate the probability of a contamination event.Third,it can make decision based on the multiple event probabilities fusion.Finally,a spatial correlation model is applied to determine the spatial-temporal contamination event in the water supply networks.The experimental results indicate that the proposed M-STAEDA algorithm can obtain more accuracy with BP neural network model and improve the rate of detection and the false alarm rate,compared with the temporal event detection of Single Variate Temporal Abnormal Event Detection Algorithm(M-STAEDA).展开更多
文摘Neoplasms of the vermiform appendix represent 1% of all gastrointestinal tumors, with epithelial and neuroendocrine histological subtypes being the most frequent. When two or more neoplasms with different components originate synchronically in the appendix with clear margin between them, it is called a collision tumor, with exceptional cases being reported in literature. The purpose is to present two new cases of collision tumors of the appendix and perform a review of the published literature. Two cases of an 82-year-old female and a 41-year-old male with collision tumors of the vermiform appendix are presented, with clinical presentation, radiological evaluation and surgical treatment exposed. Our results are compared with other published reports. In accordance with the other reported cases, both patients presented with low-grade appendiceal mucinous neoplasm (LAMN). Female patient with synchronous goblet cell carcinoma managed with a completion right colectomy and Hyperthermic intraperitoneal chemotherapy (HIPEC) and the other patient with well-differentiated neuroendocrine (NET) tumor managed with laparoscopic appendectomy without adjuvant treatment. Since very few cases have been reported, no diagnostic and therapeutic consensus and guidelines exist up to date. We agree that local, regional, and systemic therapies should be chosen according to the tumor that represents the worst prognosis.
基金Project supported by National Key Research and Development Program of China(2018YFC0115202)the Science and Technology Research Program of Chongqing Municipal Education Commission(KJZD-M201801501)the Program for Creative Research Groups in University of Chongqing(CXQT19031)。
文摘The influence of Ce-Co alloy addition and sintering holding time on permanent magnetic properties and micro structure of nanocrystalline Nd-Fe-B bulk alloy were investigated.The coercivity of Nd-Fe-B bulk alloy can be enhanced greatly by more than 100% after adding Ce-Co powders.However,when the concentration of Ce-Co is up to 30 wt%,the density of the magnet can reach the maximum value of 7.58 g/cm^(3),but the coercivity does not increase significantly.On the other hand,with the increase of holding time to 10 min,the density and coercivity of magnets increase gradually,reaching up to 7.55 g/cm^(3) and 1134.3 kA/m,respectively.After the addition of Ce-Co alloy,Ce-Co may easily diffuse into the Nd-Fe-B matrix during hot-pressing and under the high pressure and temperature,thus increasing the content of grain boundary phase and the pinning effect of grain boundary,which leads to the increase of coercivity.The extension of the hot-pressing holding time may be more conducive to the diffusion of CeCo into the Nd-Fe-B matrix.In addition,the effect of Ce-Co addition on the magnetic properties of Nd-FeB with different content of rare earth was also studied.The addition of Ce-Co can effectively increase the coercivity of nanocomposite Nd_(2)Fe_(14)B/α-Fe magnets.The addition of Nb to the parent alloy can further improve the coercivity.For Nd_(11)Fe_(81.5)Nb_(1)Ga_(0.5)B_(6) alloy with 10 wt% Ce-Co addition,the coercivity can increase from 740.28 to 1098.48 kA/m.
基金This work is supported by the Programs for the Young Talents of National Science Library,Chinese Academy of Sciences(Grant No.2019QNGR003).
文摘Purpose:Research dynamics have long been a research interest.It is a macro perspective tool for discovering temporal research trends of a certain discipline or subject.A micro perspective of research dynamics,however,concerning a single researcher or a highly cited paper in terms of their citations and“citations of citations”(forward chaining)remains unexplored.Design/methodology/approach:In this paper,we use a cross-collection topic model to reveal the research dynamics of topic disappearance topic inheritance,and topic innovation in each generation of forward chaining.Findings:For highly cited work,scientific influence exists in indirect citations.Topic modeling can reveal how long this influence exists in forward chaining,as well as its influence.Research limitations:This paper measures scientific influence and indirect scientific influence only if the relevant words or phrases are borrowed or used in direct or indirect citations.Paraphrasing or semantically similar concept may be neglected in this research.Practical implications:This paper demonstrates that a scientific influence exists in indirect citations through its analysis of forward chaining.This can serve as an inspiration on how to adequately evaluate research influence.Originality:The main contributions of this paper are the following three aspects.First,besides research dynamics of topic inheritance and topic innovation,we model topic disappearance by using a cross-collection topic model.Second,we explore the length and character of the research impact through“citations of citations”content analysis.Finally,we analyze the research dynamics of artificial intelligence researcher Geoffrey Hinton’s publications and the topic dynamics of forward chaining.
基金Supported by NSFC(10571014)NSFC(10571156)+1 种基金the Doctor Foundation of Jxnu (2443)the Natural Science Foundation of Jiangxi province(2008GZS0051)
文摘In this note, the authors prove that the commutator Tb, generated by θ-type Calderon-Zygmund operator T and a Lipschitz function b is bounded from LP（R^n） intoLip（β_n/p）（R^n） and also maps from Ln/β （R^n） into BMO（R^n）.
基金the National Key Research and Development Program of China(2018YFD0500100,2016YFD0500205)Discipline Development Grant from College of Animal Sciences FAFU(2018DK003)+3 种基金Natural Science Foundation of China(31602046)National Basic Research Program(973)of China(2015CB910502)Program for Fujian University Outstanding Youth Scientific Research,Science and Technology Innovation Special Foundation of Fujian Agriculture and Forestry University(KFA17229A)Collaborative Innovation Center of Animal Health and Food Safety Application Technology in Fujian,Fujian Vocational College of Agriculture(Kla17H01A).
文摘Beak and feather disease virus(BFDV) is an infectious agent responsible for feather degeneration and beak deformation in birds. In March 2017, an epidemic of psittacine beak and feather disease(PBFD) struck a farm in Fuzhou in the Fujian Province of southeast China, resulting in the death of 51 parrots. In this study, the disease was diagnosed and the pathogen was identified by PCR and whole genome sequencing. A distinct BFDV strain was identified and named as the FZ strain.This BFDV strain caused severe disease symptoms and pathological changes characteristic of typical PBFD in parrots, for example, loss of feathers and deformities of the beak and claws, and severe pathological changes in multiple organs of the infected birds. Phylogenetic analysis showed that the FZ strain was more closely related to the strain circulating in New Caledonia than the strains previously reported in China. Nucleotide homology between the FZ strain and other 43 strains of BFDV ranged from 80.0% to 92.0%. Blind passage experiment showed that this strain had limited replication capability in SPF Chicken Embryos and DF-1 Cells. Furthermore, the capsid(Cap) gene of this FZ strain was cloned into the p GEX-4 T-1 expression vector to prepare the polyclonal anti-Cap antibody. Western blotting analysis using the anti-Cap antibody further confirmed that the diseased parrots were infected with BFDV. In this study, a PBFD and its pathogen was identified for the first time in Fujian Province of China, suggesting that future surveillance of BFDV should be performed.
基金supported by the major project of the National Social Science Foundation of China“Big Data-driven Semantic Evaluation System of Science and Technology Literature”(Grant No.21&ZD329)。
文摘Purpose:To address the“anomalies”that occur when scientific breakthroughs emerge,this study focuses on identifying early signs and nascent stages of breakthrough innovations from the perspective of outliers,aiming to achieve early identification of scientific breakthroughs in papers.Design/methodology/approach:This study utilizes semantic technology to extract research entities from the titles and abstracts of papers to represent each paper’s research content.Outlier detection methods are then employed to measure and analyze the anomalies in breakthrough papers during their early stages.The development and evolution process are traced using literature time tags.Finally,a case study is conducted using the key publications of the 2021 Nobel Prize laureates in Physiology or Medicine.Findings:Through manual analysis of all identified outlier papers,the effectiveness of the proposed method for early identifying potential scientific breakthroughs is verified.Research limitations:The study’s applicability has only been empirically tested in the biomedical field.More data from various fields are needed to validate the robustness and generalizability of the method.Practical implications:This study provides a valuable supplement to current methods for early identification of scientific breakthroughs,effectively supporting technological intelligence decision-making and services.Originality/value:The study introduces a novel approach to early identification of scientific breakthroughs by leveraging outlier analysis of research entities,offering a more sensitive,precise,and fine-grained alternative method compared to traditional citation-based evaluations,which enhances the ability to identify nascent breakthrough innovations.
文摘Background: The mortality rate of colorectal cancer in China is on the rise, which has exceeded the global average rate, thus making the care of colorectal cancer widely concerned. As a comprehensive nursing model, the patient navigation model has shown its effectiveness in improving the quality of life among patients with chronic diseases and reducing the shortage of current healthcare resources in some area. This study aims to identify the current status and dilemma of the patient navigation model applied in colorectal cancer care in China. Methods: Bibliometric method was used to analyze published articles regarding the application of patient navigation model in colorectal cancer care retrieved from the Web of Science database. Statistics were presented using visualization method processed by the Bibliographic Items Co-occurrence Matrix Builder (BICOMB) software. Results: 124 articles, from 2006 to 2018, covering 14 countries, involving 931 researchers, 356 institutions and 60 publications were obtained;American research papers are the largest components of the aforementioned articles;only one of them is written by Chinese authors. The 3 leading institutions in this domain are University OF Rochester, Ohio State University, Icahn School of Medicine at Mount Sinai, yet the distribution of authors is relatively decentralized. “Cancer” is the main journal that publishes the researches in this domain. Research hotspots are on “cancer prevention and screening”, “health disparities”, “economic evaluation”, “patient navigators”, and “ethnicity”. Conclusion: In China, the research on the patient navigation is still in its infancy. Therefore, the Chinese government should provide more endorsement to this particular area and encourage the cooperation with other countries. China, having a long way to go, should further explore patient navigation on colorectal cancer care and establish a model that matches its cultural backgrounds.
基金The National Key Research and Development Program of China under contract No.2018YFC1406102the Funds for the Distinguished Young Scientists of Hubei Province(China)under contract No.2019CFA057the National Natural Science Foundation of China under contract Nos 41941010 and 41776200。
文摘Information on the Arctic sea ice climate indicators is crucial to business strategic planning and climate monitoring.Data on the evolvement of the Arctic sea ice and decadal trends of phenology factors during melt season are necessary for climate prediction under global warming.Previous studies on Arctic sea ice phenology did not involve melt ponds that dramatically lower the ice surface albedo and tremendously affect the process of sea ice surface melt.Temporal means and trends of the Arctic sea ice phenology from 1982 to 2017 were examined based on satellite-derived sea ice concentration and albedo measurements.Moreover,the timing of ice ponding and two periods corresponding to it were newly proposed as key stages in the melt season.Therefore,four timings,i.e.,date of snow and ice surface melt onset(MO),date of pond onset(PO),date of sea ice opening(DOO),and date of sea ice retreat(DOR);and three durations,i.e.,melt pond formation period(MPFP,i.e.,MO–PO),melt pond extension period(MPEP,i.e.,PO–DOR),and seasonal loss of ice period(SLIP,i.e.,DOO–DOR),were used.PO ranged from late April in the peripheral seas to late June in the central Arctic Ocean in Bootstrap results,whereas the pan-Arctic was observed nearly 4 days later in NASA Team results.Significant negative trends were presented in the MPEP in the Hudson Bay,the Baffin Bay,the Greenland Sea,the Kara and Barents seas in both results,indicating that the Arctic sea ice undergoes a quick transition from ice to open water,thereby extending the melt season year to year.The high correlation coefficient between MO and PO,MPFP illustrated that MO predominates the process of pond formation.
基金Project supported by the National Natural Science Foundation of China(22063010)the Youth Innovation Team of Shaanxi Universities。
文摘A novel tetra-nuclear Tb-organic network,named as [Tb_(4)(2-pyia)_(6)(HAc)_(0.5)(2,2'-bipy)(H_(2)O)_(4.5)]·2,2'-bipy·H_(2)O(1),was synthesized hydrothermally based on 5-(pyridin-2-ylmethoxy) isophthalic acid(H_(2)pyia) and 2,2'-bipyridine(2,2'-bipy) ligands,and characterized by single crystal X-ray diffraction,thermogravimetric(TG) analyses,powder X-ray diffraction(PXRD) and infrared(IR) technology.1 possesses a two-dimensional network based on the tetra-nuclear inorganic building units,and the π-πstacking interactions between the pyia^(2-) ligands and the vip 2,2'-bipy molecules play an important role in the forming of 3D supramolecular structure.1 exhibits excellent fluorescent sensing performance for Fe^(3+)(1.26×10^(-8) mol/L),Cr_(2)O_(7)^(2-)(8.1×10^(-7) mol/L),2,4,6-trinitrophenol(TNP)(2.71×10^(-8) mol/L)and tetracycline(TCT)(2.76×10^(-7) mol/L) in aqueous solution with lower detection concentrations.The sensing mechanisms of 1 were investigated by density functional theory(DFT) calculations,ultraviolet-visible(UV-Vis) diffuse reflectance spectroscopy,PXRD and fluorescent lifetime analyses.The activated product of 1 was prepared by heating at 255℃ under constant pressure and used to photo-catalytically degrade TCT.Both 1 and the activated one have good photocatalytic degradation performance for TCT with degradation rates of 84.29% and 96.07%,respectively.The photocatalytic mechanisms were discovered by UV-Vis diffuse reflectance spectroscopy and radical trap experiments.The Tb-organic framework might be an excellent multifunctional fluorescent sensor and a good photocatalytic agent for TCT degradation in the future.
基金Supported by the National Natural Science Foundation of China(Grant Nos.109610151087117310931001)
文摘In this paper, the author proves that Multiplier operator is bounded on BMO（Rn）, LMO（Rn） and CBMOPp,λ（Rn） respectively if some concellation conditions are satisfied.
基金supported by the NNSF (10961015, 11261023) of Chinathe Jiangxi Natural Science Foundation of China (20122BAB201011), GJJ12203
文摘In this note, the author prove that maximal Bocher-Riesz commutator Bδ,＊^b generated by operator Bδ,＊ and function b∈ BMO（ω） is a bounded operator from L^p（μ） into L^p（ν）, where w∈ （μν^- 1）^1/p,μ,v ∈ Ap for 1 〈 p 〈 ∞. The proof relies heavily on the pointwise estimates for the sharp maximal function of the commutator Bδ,＊^b.
基金Supported by the National Natural Science Foundation of China(Grant Nos.1196103211971209)the Natural Science Foundation of Jiangxi Province(Grant No.20191BAB201003).
文摘This note investigates the global regularity of 3D liquid crystal equations in terms of the vertical derivative of uh.More precisely,we prove that if the vertical derivative of the horizontal velocity component uh satisfiesδ_(3uh)∈L^(p)(0,T;R^(3))with 2/p+3/q≤3/2,2≤p≤∞,then the local strong solution(u,d)can be smoothly extended beyond t=T.
基金Supported by Open Fund Project of Key Laboratory of Plant Nutrition and Fertilizer,Ministry of Agriculture and Rural Affairs"Study on Precise Nutrient Demand Model of Corn"(KLPNF-2018-4)
文摘In order to provide the technological support for further implementing measures of reducing chemical pesticide to control plant diseases,the research progress on non-chemical pesticide measures to control plant diseases are reviewed from the aspects of agricultural control,botanical pesticide control and microbial pesticide control,and the development prospects are proposed,including accelerating innovative research on botani-cal pesticide control such as Chinese herb extracts,and screening microbial pesticides from valuable bio-control bacteria or plant endophyte metabolites for commercial production and utilization.
基金This work was supported by the National Natural Science Foundation of China Grants 11801192,11531006,11371367,11271290 and 11771062.
文摘The aim of this article is to review our recent work on nonlocal dynamics of non-Gaussian systems arising in a gene regulatory network.We have used the mean exit time,escape probability and maximal likely trajectory to quantify dynamical behaviors of a stochastic diferential system with non-Gaussianα-stable Lévy motions,to examine how the nonGaussianity index and noise intensity afect the gene transcription processes.
文摘Seasonal distribution of mono-modal, monsoonal rainfall across the semi-arid ecotone of sub-Saharan of West Africa is highly variable and unpredictable. The ever-present risk of drought and crop failure in this environment often results in food shortages that are met by emergency food aid. Humanitarian assistance planners would be better prepared for such interventions in a timely manner if they have reliable indicators that forewarn the impending failure of the rains. A good indicator would be a characteristic of the seasonal rainfall distribution that can be shown to be reasonably invariant over time and space. The objective of this study is to investigate whether such invariance existed for the seasonal median date (meaning the date when 50% of the seasonal total occurs). Such invariance is expected since the sun’s cyclic declination forces the advance and retreat of the Inter-tropical Front over West Africa. We examined the statistical properties of the seasonal median date for 1349 station-years of rainfall records for 30 rainfall stations in Burkina Faso and Niger with coordinates ranging from 9.88° to 18.5° north latitude and -4.77° to 13.2° longitude. The results showed that the median date was quite narrowly distributed over years with rather weak dependence on geographical coordinates. It can therefore be used as a reasonable ex-ante indicator of the success or failure of the rains as the rainy season progress.
基金This work was supported by the National Natural Science Foundation of China(grant No.81470649).
文摘This study was designed to explore the prevalence of fibrovascular proliferation not regressed in zone Ⅱ stage 3 retinopathy of prematurity(ROP)after initial intravitreal ranibizumab(IVR)injections and to explore the possible influence factors.Fifty-seven patients(108 eyes)with ROP who underwent intravitreal injection of ranibizumab between January 2013 and July 2014 participated in the retrospective study.Based on regress of fibrovascular tissue or not after initial injections of ranibizumab,eligible eyes were divided into two groups.Data was collected and analyzed with SPSS 16.0.In the study,108 eyes of 57 patients(18 females,39 males)underwent initial intravitreal injection.The mean birth weight was 1,440.0±357.7 g and the mean gestational age was 30.5±2.0 weeks.Eight of 57(14.0%)patients showed unfavorable fibrovascular proliferation after initial ranibizumab treatment within 2 weeks.Among them,11 eyes were controlled by further laser treatment and 3 eyes underwent vitrectomy.The difference of occurrence rate in hemorrhage between the two groups was significant(P<0.030),and the unfavorable group required more laser treatment(P<0.001).The incidence of unfavorable fibrovascular proliferation was relatively high,and intraocular hemorrhage was possibly associated with the progress in zone Ⅱ stage 3 ROP after initial IVR injection.
文摘With the rapid development of the society,water contamination events cause great loss if the accidents happen in the water supply system.A large number of sensor nodes of water quality are deployed in the water supply network to detect and warn the contamination events to prevent pollution from speading.If all of sensor nodes detect and transmit the water quality data when the contamination occurs,it results in the heavy communication overhead.To reduce the communication overhead,the Connected Dominated Set construction algorithm-Rule K,is adopted to select a part fo sensor nodes.Moreover,in order to improve the detection accuracy,a Spatial-Temporal Abnormal Event Detection Algorithm with Multivariate water quality data(M-STAEDA)was proposed.In M-STAEDA,first,Back Propagation neural network models are adopted to analyze the multiple water quality parameters and calculate the possible outliers.Then,M-STAEDA algorithm determines the potential contamination events through Bayesian sequential analysis to estimate the probability of a contamination event.Third,it can make decision based on the multiple event probabilities fusion.Finally,a spatial correlation model is applied to determine the spatial-temporal contamination event in the water supply networks.The experimental results indicate that the proposed M-STAEDA algorithm can obtain more accuracy with BP neural network model and improve the rate of detection and the false alarm rate,compared with the temporal event detection of Single Variate Temporal Abnormal Event Detection Algorithm(M-STAEDA).
