Interrupted Aortic Arch(IAA)combined with aortic stenosis(AS)is a rare and complex congenital cardiac anomaly that presents significant challenges in clinical management.In this letter,we aim to share our experience i...Interrupted Aortic Arch(IAA)combined with aortic stenosis(AS)is a rare and complex congenital cardiac anomaly that presents significant challenges in clinical management.In this letter,we aim to share our experience in performing hybrid procedures on an infant diagnosed with IAA combined with bicuspid AS.This child exhibited significant recovery during follow-up.展开更多
The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the result...The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the results of multi-center clinical nutrition research for congenital heart disease following thefirst Chinese consensus edition of 2016.The consensus was also shaped by the results of three discussion sessions and two questionnaires con-ducted by the 13-member collaboration group.This process was informed by both clinical guidelines and expert consensus.The quality of literature,both in English and Chinese,and the level of recommendations were evaluated using the Grading of Recommendations Assessment,Development,and Evaluations(GRADE)system.展开更多
Objective To develop a model using patient-specific computational fluid dynamics(CFD)to predict the required anastomotic size for total anomalous pulmonary venous connection(TAPVC)surgery and to forecast surgical outc...Objective To develop a model using patient-specific computational fluid dynamics(CFD)to predict the required anastomotic size for total anomalous pulmonary venous connection(TAPVC)surgery and to forecast surgical outcomes.Methods Based on clinical data from patients,a CFD model was used to simulate the anastomosis between pulmonary venous confluence and the left atrium.Blood flow velocity,wall shear stress,power loss,and pressure were calculated using numerical algorithms within the model.Various sizes of anastomosis were applied during the simulation.The energy dissipation at the anastomosis was computed from the results and compared with real-world data.Results As the simulated anastomotic size increased,blood flow velocity,pulmonary venous pressure,and energy loss decreased.However,when the anastomotic size exceeded 18 mm,the efficiency of energy conversion no longer improved.The realistic and simulated velocities matched well for anastomosis sizes ranging from 15 to 20 mm.Conclusion The model can assist surgeons in preoperative planning for determining the anastomotic size in TAPVC surgical treatment.展开更多
基金Supported by Zhejiang University Scientific Research Development Project(2021FZZX005-06).
文摘Interrupted Aortic Arch(IAA)combined with aortic stenosis(AS)is a rare and complex congenital cardiac anomaly that presents significant challenges in clinical management.In this letter,we aim to share our experience in performing hybrid procedures on an infant diagnosed with IAA combined with bicuspid AS.This child exhibited significant recovery during follow-up.
基金supported by the National Natural Science Foundation of China(81970265,82270310)a Sub-Project of the National Key R&D Program“The recognition and Identification of Genetic Pathogenic Genes for Structural Birth Defects”(2021YFC2701002)+1 种基金Nanjing Science and Technology Development Project(2019060007)Jiangsu Provincial Key Research and Development Program(BE2023662).
文摘The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the results of multi-center clinical nutrition research for congenital heart disease following thefirst Chinese consensus edition of 2016.The consensus was also shaped by the results of three discussion sessions and two questionnaires con-ducted by the 13-member collaboration group.This process was informed by both clinical guidelines and expert consensus.The quality of literature,both in English and Chinese,and the level of recommendations were evaluated using the Grading of Recommendations Assessment,Development,and Evaluations(GRADE)system.
基金supported by the Basic Public Welfare Research Program of Zhejiang Province(LY23H020007).
文摘Objective To develop a model using patient-specific computational fluid dynamics(CFD)to predict the required anastomotic size for total anomalous pulmonary venous connection(TAPVC)surgery and to forecast surgical outcomes.Methods Based on clinical data from patients,a CFD model was used to simulate the anastomosis between pulmonary venous confluence and the left atrium.Blood flow velocity,wall shear stress,power loss,and pressure were calculated using numerical algorithms within the model.Various sizes of anastomosis were applied during the simulation.The energy dissipation at the anastomosis was computed from the results and compared with real-world data.Results As the simulated anastomotic size increased,blood flow velocity,pulmonary venous pressure,and energy loss decreased.However,when the anastomotic size exceeded 18 mm,the efficiency of energy conversion no longer improved.The realistic and simulated velocities matched well for anastomosis sizes ranging from 15 to 20 mm.Conclusion The model can assist surgeons in preoperative planning for determining the anastomotic size in TAPVC surgical treatment.
