Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy...Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).展开更多
Satellite glial cells surround neurons within dorsal root ganglia. Previous studies have focused on single-cell suspensions of cultured neurons derived from rat dorsal root ganglia. At present, the primary culture met...Satellite glial cells surround neurons within dorsal root ganglia. Previous studies have focused on single-cell suspensions of cultured neurons derived from rat dorsal root ganglia. At present, the primary culture method for satellite glial cells derived from rat dorsal root ganglia requires no digestion skill. Hence, the aim of the present study was to establish a novel primary culture method for satellite glial cells derived from dorsal root ganglia. Neonatal rat spine was collected and an incision made to expose the transverse protrusion and remove dorsal root ganglia. Dorsal root ganglia were freed from nerve fibers, connective tissue, and capsule membranes, then rinsed and transferred to 6-well plates, and cultured in a humidified 5% CO_2 incubator at 37°C. After 3 days in culture, some cells had migrated from dorsal root ganglia. After subculture, cells were identified by immunofluorescence labeling for three satellite glial cell-specific markers: glutamine synthetase, glial fibrillary acidic protein, and S100β. Cultured cells expressed glutamine synthetase, glial fibrillary acidic protein, and S100β, suggesting they are satellite glial cells with a purity of > 95%. Thus, we have successfully established a novel primary culture method for obtaining high-purity satellite glial cells from rat dorsal root ganglia without digestion.展开更多
We propose to use transverse momentum pT distribution of J/ψ production at the future Electron Ion Collider(EIC)to explore the production mechanism of heavy quarkonia in high energy collisions.We apply QCD and QED co...We propose to use transverse momentum pT distribution of J/ψ production at the future Electron Ion Collider(EIC)to explore the production mechanism of heavy quarkonia in high energy collisions.We apply QCD and QED collinear factorization to the production of a cc pair at high pT,and non-relativistic QCD factorization to the hadronization of the pair to a J/ψ.We evaluate J/ψ pT-distribution at both leading and next-to-leading order in strong coupling,and show that production rates for various color-spin channels of a cc pair in electronhadron collisions are very different from that in hadron-hadron collisions,which provides a strong discriminative power to determine various transition rates for the pair to become a J/ψ.We predict that the J/ψproduced in electron-hadron collisions is likely unpolarized,and the production is an ideal probe for gluon distribution of colliding hadron(or nucleus).We find that the J/ψ production is dominated by the color-octet channel,providing an excellent probe to explore the gluon medium in large nuclei at the EIC.展开更多
基金supported by the National Key Research and Development Program of China(No.2022YFA1602200)the National Natural Science Foundation of China(Nos.12341501 and 12405174)the Hefei Comprehensive National Science Center for the strong support on the STCF key technology research project.
文摘Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).
基金supported by the National Natural Science Foundation of China,No.31560295(to LYL)the Priority Union Foundation of Yunnan Department of Science and Technology and Kunming Medical University of China,No.2015FB098(to JHG)+1 种基金the Project of Major Scientific and Technological Achievements Cultivation of Kunming Medical University of China,No.CGPY201802(to LYL)the Health Science and Technology Plan Projects of Yunnan Province of China,No.2014NS202(to JHG)
文摘Satellite glial cells surround neurons within dorsal root ganglia. Previous studies have focused on single-cell suspensions of cultured neurons derived from rat dorsal root ganglia. At present, the primary culture method for satellite glial cells derived from rat dorsal root ganglia requires no digestion skill. Hence, the aim of the present study was to establish a novel primary culture method for satellite glial cells derived from dorsal root ganglia. Neonatal rat spine was collected and an incision made to expose the transverse protrusion and remove dorsal root ganglia. Dorsal root ganglia were freed from nerve fibers, connective tissue, and capsule membranes, then rinsed and transferred to 6-well plates, and cultured in a humidified 5% CO_2 incubator at 37°C. After 3 days in culture, some cells had migrated from dorsal root ganglia. After subculture, cells were identified by immunofluorescence labeling for three satellite glial cell-specific markers: glutamine synthetase, glial fibrillary acidic protein, and S100β. Cultured cells expressed glutamine synthetase, glial fibrillary acidic protein, and S100β, suggesting they are satellite glial cells with a purity of > 95%. Thus, we have successfully established a novel primary culture method for obtaining high-purity satellite glial cells from rat dorsal root ganglia without digestion.
基金Guangdong Major Project of Basic and Applied Basic Research(Grant No.2020B0301030008)the National Natural Science Foundation of China(Grant Nos.12022512 and 12035007)+3 种基金Science and Technology Program of Guangzhou(Grant No.2019050001)supported by the U.S.Department of Energy(Grant No.DE-AC05-06OR23177),under which Jefferson Science Associates,LLC,manages and operates Jefferson Labsupported by the U.S.Department of Energy,Division of High Energy Physics(Grant No.DE-AC02-06CH11357)supported within the framework of the TMD Topical Collaboration。
文摘We propose to use transverse momentum pT distribution of J/ψ production at the future Electron Ion Collider(EIC)to explore the production mechanism of heavy quarkonia in high energy collisions.We apply QCD and QED collinear factorization to the production of a cc pair at high pT,and non-relativistic QCD factorization to the hadronization of the pair to a J/ψ.We evaluate J/ψ pT-distribution at both leading and next-to-leading order in strong coupling,and show that production rates for various color-spin channels of a cc pair in electronhadron collisions are very different from that in hadron-hadron collisions,which provides a strong discriminative power to determine various transition rates for the pair to become a J/ψ.We predict that the J/ψproduced in electron-hadron collisions is likely unpolarized,and the production is an ideal probe for gluon distribution of colliding hadron(or nucleus).We find that the J/ψ production is dominated by the color-octet channel,providing an excellent probe to explore the gluon medium in large nuclei at the EIC.