试验旨在探究斑蝥黄微胶囊产品制备的优化工艺参数。通过单因素试验,分析溶剂类别、溶解温度和时间以及微胶囊包埋壁材、乳化剂等因素对微囊化斑蝥黄产品的影响,确定了斑蝥黄最佳溶解工艺条件、微囊化最佳包埋壁材与乳化剂;然后通过正...试验旨在探究斑蝥黄微胶囊产品制备的优化工艺参数。通过单因素试验,分析溶剂类别、溶解温度和时间以及微胶囊包埋壁材、乳化剂等因素对微囊化斑蝥黄产品的影响,确定了斑蝥黄最佳溶解工艺条件、微囊化最佳包埋壁材与乳化剂;然后通过正交试验分析,针对产品感观质量和稳定性等因素,得出了合理的微囊化斑蝥黄10%冷水溶性(Cold Water Solubility,CWS)产品配方。结果表明:最佳工艺条件是以二氯甲烷作溶剂,溶解温度50℃,瞬时溶解时间少于5 min,且斑蝥黄与二氯甲烷的最佳比值为12∶135。斑蝥黄微囊化过程中最佳包埋壁材为木质素磺酸盐,最佳乳化剂为抗坏血酸棕榈酸酯;产品配方为斑蝥黄12%、DL-α生育酚4.5%、抗坏血酸棕榈酸酯3.5%、大豆磷脂3.0%、木质素磺酸盐35%、麦芽糊精22%、玉米淀粉20%。“瞬时溶解、二次乳化和均质、双重包埋”技术的应用可在很大程度上提高斑蝥黄微胶囊产品的稳定性、水溶性、安全性以及生物利用率。展开更多
近期在琼东南盆地超深水区发现了L18气田上新统地层圈闭气田,但在聚气背景、烃源岩、储层沉积成因及天然气输导体系等气田形成条件和成藏模式认识存在争议。通过对该气田形成条件的综合分析,认为上新世轴向古洼槽内地层圈闭、陵水凹陷...近期在琼东南盆地超深水区发现了L18气田上新统地层圈闭气田,但在聚气背景、烃源岩、储层沉积成因及天然气输导体系等气田形成条件和成藏模式认识存在争议。通过对该气田形成条件的综合分析,认为上新世轴向古洼槽内地层圈闭、陵水凹陷东洼下渐新统崖城组浅海相烃源岩、上新统限制型重力流砂岩储层和渐新统-中新统断裂垂向沟源通道是形成上新统地层圈闭气田的4个基本条件。中中新世以来盆地中央继承性发育轴向古洼槽和限制型重力流沉积,随着后期地层沉积迁移、差异压实作用,上新统莺歌海组砂岩顶面在轴向洼槽内起伏,并被周边泥岩封盖、封堵,形成了地层圈闭;约3.4 Ma BP,陵水凹陷东洼下渐新统崖城组浅海相烃源岩生成了成熟天然气,沿渐新统-中新统断裂向上运移到上新统莺歌海组重力流沉积砂岩中,再侧向运移至地层圈闭中聚集成藏,具有"烃源岩、圈闭、断裂+砂岩输导层"三要素控藏的上新统地层圈闭成藏模式。展开更多
Crude oil has been discovered in the Paleogene and Neogene units of the Weixinan Sag in the Beibu Gulf Basin.To determine the source and accumulation mode of this crude oil,12 crude oil samples and 27 source rock samp...Crude oil has been discovered in the Paleogene and Neogene units of the Weixinan Sag in the Beibu Gulf Basin.To determine the source and accumulation mode of this crude oil,12 crude oil samples and 27 source rock samples were collected and an extensive organic geochemical analysis was conducted on them.Based on the geological conditions and the analytical results,the types,origins and accumulation patterns of crude oil in the study area were elucidated.Except for a shallowly-buried and biodegraded crude oil deposit in Neogene rocks,the crude oil samples in the study area were normal.All of the crude oils were derived from lacustrine source rocks.According to biomarker compositions,the crude oils could be divided into two families,A and B,distinctions that were reinforced by differences in carbon isotope composition and spatial distribution.Oil-source correlation analysis based on biomarkers revealed that Family A oils were derived from the mature oil shale at the bottom of the second member of the Liushagang Formation,while the Family B oils formed in the mature shale of the Liushagang Formation.The Family A oils,generated by oil shale,mainly migrated laterally along sand bodies and were then redistributed in adjacent reservoirs above and below the oil shale layer,as well as in shallow layers at high structural positions,occupying a wide distribution range.The Family B oils were generated by other shale units before migrating vertically along faults to form reservoirs nearby,resulting in a narrow distribution range.展开更多
文摘试验旨在探究斑蝥黄微胶囊产品制备的优化工艺参数。通过单因素试验,分析溶剂类别、溶解温度和时间以及微胶囊包埋壁材、乳化剂等因素对微囊化斑蝥黄产品的影响,确定了斑蝥黄最佳溶解工艺条件、微囊化最佳包埋壁材与乳化剂;然后通过正交试验分析,针对产品感观质量和稳定性等因素,得出了合理的微囊化斑蝥黄10%冷水溶性(Cold Water Solubility,CWS)产品配方。结果表明:最佳工艺条件是以二氯甲烷作溶剂,溶解温度50℃,瞬时溶解时间少于5 min,且斑蝥黄与二氯甲烷的最佳比值为12∶135。斑蝥黄微囊化过程中最佳包埋壁材为木质素磺酸盐,最佳乳化剂为抗坏血酸棕榈酸酯;产品配方为斑蝥黄12%、DL-α生育酚4.5%、抗坏血酸棕榈酸酯3.5%、大豆磷脂3.0%、木质素磺酸盐35%、麦芽糊精22%、玉米淀粉20%。“瞬时溶解、二次乳化和均质、双重包埋”技术的应用可在很大程度上提高斑蝥黄微胶囊产品的稳定性、水溶性、安全性以及生物利用率。
文摘近期在琼东南盆地超深水区发现了L18气田上新统地层圈闭气田,但在聚气背景、烃源岩、储层沉积成因及天然气输导体系等气田形成条件和成藏模式认识存在争议。通过对该气田形成条件的综合分析,认为上新世轴向古洼槽内地层圈闭、陵水凹陷东洼下渐新统崖城组浅海相烃源岩、上新统限制型重力流砂岩储层和渐新统-中新统断裂垂向沟源通道是形成上新统地层圈闭气田的4个基本条件。中中新世以来盆地中央继承性发育轴向古洼槽和限制型重力流沉积,随着后期地层沉积迁移、差异压实作用,上新统莺歌海组砂岩顶面在轴向洼槽内起伏,并被周边泥岩封盖、封堵,形成了地层圈闭;约3.4 Ma BP,陵水凹陷东洼下渐新统崖城组浅海相烃源岩生成了成熟天然气,沿渐新统-中新统断裂向上运移到上新统莺歌海组重力流沉积砂岩中,再侧向运移至地层圈闭中聚集成藏,具有"烃源岩、圈闭、断裂+砂岩输导层"三要素控藏的上新统地层圈闭成藏模式。
文摘Crude oil has been discovered in the Paleogene and Neogene units of the Weixinan Sag in the Beibu Gulf Basin.To determine the source and accumulation mode of this crude oil,12 crude oil samples and 27 source rock samples were collected and an extensive organic geochemical analysis was conducted on them.Based on the geological conditions and the analytical results,the types,origins and accumulation patterns of crude oil in the study area were elucidated.Except for a shallowly-buried and biodegraded crude oil deposit in Neogene rocks,the crude oil samples in the study area were normal.All of the crude oils were derived from lacustrine source rocks.According to biomarker compositions,the crude oils could be divided into two families,A and B,distinctions that were reinforced by differences in carbon isotope composition and spatial distribution.Oil-source correlation analysis based on biomarkers revealed that Family A oils were derived from the mature oil shale at the bottom of the second member of the Liushagang Formation,while the Family B oils formed in the mature shale of the Liushagang Formation.The Family A oils,generated by oil shale,mainly migrated laterally along sand bodies and were then redistributed in adjacent reservoirs above and below the oil shale layer,as well as in shallow layers at high structural positions,occupying a wide distribution range.The Family B oils were generated by other shale units before migrating vertically along faults to form reservoirs nearby,resulting in a narrow distribution range.
