The infrared band contains rich opportunities for astronomical research,but due to the limitations of infrared technology,the development of infrared astronomy in China has been far from satisfactory for a long time,e...The infrared band contains rich opportunities for astronomical research,but due to the limitations of infrared technology,the development of infrared astronomy in China has been far from satisfactory for a long time,especially for solar observation.“Accurate Infrared Magnetic field Measurements of the Sun”project(AIMS)is a National Major Scientific Research Instrument Development Project(recommended by the Ministries)supported by the National Natural Science Foundation of China.It is aimed at improving the accuracy of magnetic field measurement by an order of magnitude,by measuring the“Zeeman splitting”directly.In addition,as AIMS is also the first equipment specifically designed for mid-to far-infrared solar observation in the world,we also hope to utilize AIMS to explore potential new scientific research opportunities in the vast infrared region.This article will briefly introduce the scientific objectives,the telescope,the scientific post-focus instruments,and finally summarize the commissioning observations of AIMS.展开更多
Spatial mode(de)multiplexiing of orbital angular momentum(OAM)beams is a promising solution to address future bandwidth issues,but the rapidly increasing divergence with the mode order severely limits the practically ...Spatial mode(de)multiplexiing of orbital angular momentum(OAM)beams is a promising solution to address future bandwidth issues,but the rapidly increasing divergence with the mode order severely limits the practically addressable number of OAM modes.Here we present a set of multi-vortex geometric beams(MVGBs)as high-dimensional information carriers for free-space optical communication,by virtue of three independent degrees of freedom(DoFs)including central OAM,sub-beam OAM,and coherent-state phase.The novel modal basis set has high divergence degeneracy,and highly consistent propagation behaviors among all spatial modes,capable of increasing the addressable spatial channels by two orders of magnitude than OAM basis as predicted.We experimentally realize the tri-DoF MVGB mode(de)multiplexing and data transmission by the conjugated modulation method,demonstrating lower error rates caused by center offset and coherent background noise,compared with OAM basis.Our work provides a potentially useful basis for the next generation of large-scale dense data communication.展开更多
Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves ...Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves were administrated with 0(control) or 150,000 IU vitamin A(retinyl palmitate in glycerol,i.m.) per calf at birth and 1 month of age.At 2 months of age,a biopsy of the Biceps femoris muscle was obtained to analyze the immediate effects of vitamin A injection on myogenic capacity of muscle cells.The resulting steers were harvested at 14 months of age.Results: Vitamin A administration increased cattle growth at 2 months.At 2 months of age,Vitamin A increased PAX7 positive satellite cells and the expression of myogenic marker genes including PAX7,MYF5,MYOD and MYOG.Muscle derived mononuclear cells were further isolated and induced myogenesis in vitro.More myotubes and a higher degree of myogenesis was observed in vitamin A groups.Consistently,vitamin A increased Latissimus dorsi(LD) muscle fiber size at harvest.In addition,vitamin A increased the ratio of oxidative type I and type IIA fibers and reduced the glycolic type IIX fibers.Furthermore,we found that RA,a key bioactive metabolite of vitamin A,activated PPARGC1 A promoter,which explains the upregulated expression of PPARGC1 A in skeletal muscle.Conclusion: Vitamin A administration to neonatal calves enhanced postnatal muscle growth by promoting myogenesis and increasing satellite cell density,accompanied with a shift to oxidative muscle fibers.展开更多
The formation of humins hampers the large-scale production of 5-hydroxymethylfurfural(HMF)in biorefinery.Here,a detailed reaction network of humin formation at the initial stage of fructose-to-HMF dehydration in water...The formation of humins hampers the large-scale production of 5-hydroxymethylfurfural(HMF)in biorefinery.Here,a detailed reaction network of humin formation at the initial stage of fructose-to-HMF dehydration in water is delineated by combined experimental,spectroscopic,and theoretical studies.Three bimolecular reaction pathways to build up soluble humins are demonstrated.That is,the intermolecular etherification of β-furanose at room temperature initiates the C12 path,whereas the C-C cleavage of a-furanose at 130-150℃ leads to C11 path,and that of open-chain fructose at 180℃ to C11' path.The successive intramolecular dehydrations and condensations of the as-formed bimolecular intermediates lead to three types of soluble humins.We show that the C12 path could be restrained by using HCl or AlCl_(3) catalyst,and both the C12 and C110 paths could be effectively inhibited by adding THF as a co-solvent or accelerating heating rate via microwave heating.展开更多
The dried roots of Aconitum pendulum Busch are the major source of a commonly used Tibetan medicine,namely Tiebangchui(TBC)(Fig.S1).However,raw TBC contains a large amount of high toxic diester-diterpenoid alkaloids(D...The dried roots of Aconitum pendulum Busch are the major source of a commonly used Tibetan medicine,namely Tiebangchui(TBC)(Fig.S1).However,raw TBC contains a large amount of high toxic diester-diterpenoid alkaloids(DDAs),and the improper use would cause arrhythmia,irreversible cardiovascular damages,and even death.“Paozhi”,an appropriate processing method,is the essential prerequisite for the safe clinical application of TBC.Water-decocting and sand-frying are commonly used processing methods for toxicity attenuation and efficacy preservation for TBC.展开更多
文摘The infrared band contains rich opportunities for astronomical research,but due to the limitations of infrared technology,the development of infrared astronomy in China has been far from satisfactory for a long time,especially for solar observation.“Accurate Infrared Magnetic field Measurements of the Sun”project(AIMS)is a National Major Scientific Research Instrument Development Project(recommended by the Ministries)supported by the National Natural Science Foundation of China.It is aimed at improving the accuracy of magnetic field measurement by an order of magnitude,by measuring the“Zeeman splitting”directly.In addition,as AIMS is also the first equipment specifically designed for mid-to far-infrared solar observation in the world,we also hope to utilize AIMS to explore potential new scientific research opportunities in the vast infrared region.This article will briefly introduce the scientific objectives,the telescope,the scientific post-focus instruments,and finally summarize the commissioning observations of AIMS.
基金This work was funded by the National Natural Science Foundation of China(61975087).
文摘Spatial mode(de)multiplexiing of orbital angular momentum(OAM)beams is a promising solution to address future bandwidth issues,but the rapidly increasing divergence with the mode order severely limits the practically addressable number of OAM modes.Here we present a set of multi-vortex geometric beams(MVGBs)as high-dimensional information carriers for free-space optical communication,by virtue of three independent degrees of freedom(DoFs)including central OAM,sub-beam OAM,and coherent-state phase.The novel modal basis set has high divergence degeneracy,and highly consistent propagation behaviors among all spatial modes,capable of increasing the addressable spatial channels by two orders of magnitude than OAM basis as predicted.We experimentally realize the tri-DoF MVGB mode(de)multiplexing and data transmission by the conjugated modulation method,demonstrating lower error rates caused by center offset and coherent background noise,compared with OAM basis.Our work provides a potentially useful basis for the next generation of large-scale dense data communication.
基金supported by Agriculture and Food Research Initiative Competitive Grants No.2015–67015-23219 and 2016–68006-24634 from the USDA National Institute of Food and Agriculture
文摘Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves were administrated with 0(control) or 150,000 IU vitamin A(retinyl palmitate in glycerol,i.m.) per calf at birth and 1 month of age.At 2 months of age,a biopsy of the Biceps femoris muscle was obtained to analyze the immediate effects of vitamin A injection on myogenic capacity of muscle cells.The resulting steers were harvested at 14 months of age.Results: Vitamin A administration increased cattle growth at 2 months.At 2 months of age,Vitamin A increased PAX7 positive satellite cells and the expression of myogenic marker genes including PAX7,MYF5,MYOD and MYOG.Muscle derived mononuclear cells were further isolated and induced myogenesis in vitro.More myotubes and a higher degree of myogenesis was observed in vitamin A groups.Consistently,vitamin A increased Latissimus dorsi(LD) muscle fiber size at harvest.In addition,vitamin A increased the ratio of oxidative type I and type IIA fibers and reduced the glycolic type IIX fibers.Furthermore,we found that RA,a key bioactive metabolite of vitamin A,activated PPARGC1 A promoter,which explains the upregulated expression of PPARGC1 A in skeletal muscle.Conclusion: Vitamin A administration to neonatal calves enhanced postnatal muscle growth by promoting myogenesis and increasing satellite cell density,accompanied with a shift to oxidative muscle fibers.
基金the National Natural Science Foundation of China(No.21875149)111 project(B17030)the Basal Research Fund of the Central University.
文摘The formation of humins hampers the large-scale production of 5-hydroxymethylfurfural(HMF)in biorefinery.Here,a detailed reaction network of humin formation at the initial stage of fructose-to-HMF dehydration in water is delineated by combined experimental,spectroscopic,and theoretical studies.Three bimolecular reaction pathways to build up soluble humins are demonstrated.That is,the intermolecular etherification of β-furanose at room temperature initiates the C12 path,whereas the C-C cleavage of a-furanose at 130-150℃ leads to C11 path,and that of open-chain fructose at 180℃ to C11' path.The successive intramolecular dehydrations and condensations of the as-formed bimolecular intermediates lead to three types of soluble humins.We show that the C12 path could be restrained by using HCl or AlCl_(3) catalyst,and both the C12 and C110 paths could be effectively inhibited by adding THF as a co-solvent or accelerating heating rate via microwave heating.
基金supported by the National Natural Science Foundation of China(Grant No.:82130113)the National Key R&D Program of China(Program No.:2023YFC3504402)+2 种基金the China Postdoctoral Science Foundation(Grant No.:2021MD703800)the Science Foundation for Youths of Science&Technology Department of Sichuan Province(Grant Nos.:2023NSFSC1775,2022NSFSC1449)the“Xinglin Scholars”Research Promotion Program of Chengdu University of TCM(Grant Nos.:BSH2021009,QJRC2022044).
文摘The dried roots of Aconitum pendulum Busch are the major source of a commonly used Tibetan medicine,namely Tiebangchui(TBC)(Fig.S1).However,raw TBC contains a large amount of high toxic diester-diterpenoid alkaloids(DDAs),and the improper use would cause arrhythmia,irreversible cardiovascular damages,and even death.“Paozhi”,an appropriate processing method,is the essential prerequisite for the safe clinical application of TBC.Water-decocting and sand-frying are commonly used processing methods for toxicity attenuation and efficacy preservation for TBC.
