Detecting small forest fire targets in unmanned aerial vehicle(UAV)images is difficult,as flames typically cover only a very limited portion of the visual scene.This study proposes Context-guided Compact Lightweight N...Detecting small forest fire targets in unmanned aerial vehicle(UAV)images is difficult,as flames typically cover only a very limited portion of the visual scene.This study proposes Context-guided Compact Lightweight Network(CCLNet),an end-to-end lightweight model designed to detect small forest fire targets while ensuring efficient inference on devices with constrained computational resources.CCLNet employs a three-stage network architecture.Its key components include three modules.C3F-Convolutional Gated Linear Unit(C3F-CGLU)performs selective local feature extraction while preserving fine-grained high-frequency flame details.Context-Guided Feature Fusion Module(CGFM)replaces plain concatenation with triplet-attention interactions to emphasize subtle flame patterns.Lightweight Shared Convolution with Separated Batch Normalization Detection(LSCSBD)reduces parameters through separated batch normalization while maintaining scale-specific statistics.We build TF-11K,an 11,139-image dataset combining 9139 self-collected UAV images from subtropical forests and 2000 re-annotated frames from the FLAME dataset.On TF-11K,CCLNet attains 85.8%mAP@0.5,45.5%mean Average Precision(mAP)@[0.5:0.95],87.4%precision,and 79.1%recall with 2.21 M parameters and 5.7 Giga Floating-point Operations Per Second(GFLOPs).The ablation study confirms that each module contributes to both accuracy and efficiency.Cross-dataset evaluation on DFS yields 77.5%mAP@0.5 and 42.3%mAP@[0.5:0.95],indicating good generalization to unseen scenes.These results suggest that CCLNet offers a practical balance between accuracy and speed for small-target forest fire monitoring with UAVs.展开更多
Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of h...Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of high-temperature treatments has introduced uncertainties regarding the compositions and microstructures of resulting derivatives.Additionally,complete carbonization has led to diminished yields of the produced carbon composites,significantly limiting their practical applications.Consequently,the exploration of pristine MOF-based EMW absorbers presents an intriguing yet challenging endeavor,primarily due to inherently low electrical conductivity.In this study,we showcase the utilization of structurally robust Zr-MOFs as scaffolds to build highly conductive Zr-MOF/PPy composites via an inner-outer dual-modification approach,which involves the production of conducting polypyrrole(PPy)both within the confined nanoporous channels and the external surface of Zr-MOFs via post-synthetic modification.The interconnection of confined PPy and surface-lined PPy together leads to a consecutive and extensive conducting network to the maximum extent.This therefore entails outstanding conductivity up to~14.3 S cm^(-1) in Zr-MOF/PPy composites,which is approximately 1-2 orders of magnitude higher than that for conductive MOF nanocomposites constructed from either inner or outer modification.Benefiting from the strong and tunable conduction loss,as well as the induced dielectric polarization originated from the porous structures and MOF-polymer interfaces,Zr-MOF/PPy exhibits excellent microwave attenuation capabilities and a tunable absorption frequency range.Specifically,with only 15 wt.%loading,the minimum reflection loss(RLmin)can reach up to-67.4 dB,accompanied by an effective absorption bandwidth(EAB)extending to 6.74 GHz.Furthermore,the microwave absorption characteristics can be tailored from the C-band to the Ku-band by adjusting the loading of PPy.This work provides valuable insights into the fabrication of conductive MOF composites by presenting a straightforward pathway to enhance and reg-ulate electrical conduction in MOF-based nanocomposites,thus paving a way to facilely fabricate pristine MOF-based microwave absorbers.展开更多
In order to further promote the standardization of diagnosis and treatment of gastrointestinal stromal tumor （GIST） in China, the members of Chinese Society of Clinical Oncology （CSCO） Expert Committee on GIST tho...In order to further promote the standardization of diagnosis and treatment of gastrointestinal stromal tumor （GIST） in China, the members of Chinese Society of Clinical Oncology （CSCO） Expert Committee on GIST thoroughly discussed the key contents of the consensus guidelines, and voted on the controversial issue. In final, the Chinese consensus guidelines for the diagnosis and management of GIST （2017 edition） was formed on the basis of 2013 edition consensus guidelines, which is hereby announced. The consensus included the pathological diagnosis, recurrence risk classification evaluation, targeted agent therapy, surgery and principles of surveillance of GIST.展开更多
BACKGROUND Dilated cardiomyopathy(DCM)is a common cause of systolic heart failure,and is the most prevalent type of non-ischemic cardiomyopathy.Primary hyperparathyroidism(PHPT)is characterized by hypercalcemia and ex...BACKGROUND Dilated cardiomyopathy(DCM)is a common cause of systolic heart failure,and is the most prevalent type of non-ischemic cardiomyopathy.Primary hyperparathyroidism(PHPT)is characterized by hypercalcemia and excessive secretion of parathyroid hormone(PTH).Generally,PHPT is asymptomatic and is incidentally identified during routine laboratory assessments.CASE SUMMARY This case report details a 52-year-old man diagnosed with DCM and refractory hypercalcemia,who presented with clinical manifestations including dyspnea,recurrent anorexia,and abdominal distention.Laboratory investigations indicated an elevated serum PTH level,and the sestamibi scan suggested the presence of a parathyroid adenoma.Hence,the patient underwent a parathyroidectomy,which pathologically confirmed the diagnosis of a parathyroid adenoma.Postoperatively,the patient's hypercalcemia was corrected,the dimensions of the cardiac chambers were reduced,and there was a marked improvement in cardiac function.CONCLUSION Our findings emphasize the importance of PTH assessment in patients with DCM and concurrent hypercalcemia.展开更多
Aluminum(Al)exhibits excellent electrical conductivity,mechanical ductility,and good chemical compatibility with high-ionic-conductivity electrolytes.This makes it more suitable as an anode material for all-solid-stat...Aluminum(Al)exhibits excellent electrical conductivity,mechanical ductility,and good chemical compatibility with high-ionic-conductivity electrolytes.This makes it more suitable as an anode material for all-solid-state lithium batteries(ASSLBs)compared to the overly reactive metallic lithium anode and the mechanically weak silicon anode.This study finds that the pre-lithiated Al anode demonstrates outstanding interfacial stability with the Li_6PS_5Cl(LPSCl)electrolyte,maintaining stable cycling for over 1200 h under conditions of deep charge-discharge.This paper combines the pre-lithiated Al anode with a high-nickel cathode,LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2),paired with the highly ionic conductive LPSCl electrolyte,to design an ASSLB with high energy density and stability.Using anode pre-lithiation techniques,along with dual-reinforcement technology between the electrolyte and the cathode active material,the ASSLB achieves stable cycling for 1000 cycles at a 0.2C rate,with a capacity retention rate of up to 82.2%.At a critical negative-to-positive ratio of 1.1,the battery's specific energy reaches up to 375 Wh kg^(-1),and it maintains over 85.9%of its capacity after 100 charge-discharge cycles.This work provides a new approach and an excellent solution for developing low-cost,high-stability all-solid-state batteries.展开更多
Hyperuricemia(HUA)refers to a condition where fasting serum uric acid levels exceed 420μmol/L in men and 350μmol/L in women,affecting 17.4%of China’s general population,showing increasing prevalence among younger i...Hyperuricemia(HUA)refers to a condition where fasting serum uric acid levels exceed 420μmol/L in men and 350μmol/L in women,affecting 17.4%of China’s general population,showing increasing prevalence among younger individuals.Luteolin,a common flavonoid compound,exhibits multiple biological effects,including inhibition of tumor proliferation and inflammatory responses.It also suppresses the activity of urate transporter 1(URAT1),promoting uric acid excretion.This study is the first to integrate network toxicology and network pharmacology approaches to systematically analyze the multi-target mechanisms of adenine-induced HUA and luteolin-treated HUA,with molecular docking validation of interaction targets.We constructed compound-pathway-intersection gene networks and a dual-group PPI network to analyze the mechanisms of adenine-induced HUA and luteolin-treated HUA.The dual-group PPI network identified 7 shared targets,namely XDH,PYGL,IL10,PPARG,TNF,VEGFA,and MAOA,involving core intersecting pathways such as purine-xanthine metabolism and insulin resistance.Luteolin may activate PPARG to regulate inflammation and uric acid excretion modules in the adenine network.GO-KEGG analysis indicates that intersection genes for adenine pathogenesis involve diverse biological processes,cellular components,and molecular functions,with core target KEGG analysis revealing 15 signaling pathways.Luteolin’s therapeutic targets are associated with more entries,and its core target KEGG analysis identified 46 signaling pathways.Molecular docking shows TNF,PPARG,and PYGL bind to both luteolin and adenine with negative binding energies,and luteolin’s binding energies are all below 5 kJ/mol,confirming stable binding.Luteolin’s anti-HUA mechanism is characterized by inhibition of production,promotion of excretion,anti-inflammation and metabolic regulation,but interactions with gut microbiota metabolites require further study.展开更多
KangBingDuKouFuYe(KBDKFY)is widely used to treat influenza,upper respiratory tract infections,mumps and other diseases.Due to their diverse active ingredients,it is believed that they may have excellent anti-inflammat...KangBingDuKouFuYe(KBDKFY)is widely used to treat influenza,upper respiratory tract infections,mumps and other diseases.Due to their diverse active ingredients,it is believed that they may have excellent anti-inflammatory,antibacterial and antiviral effects.Therefore,we believe they may have multiple therapeutic targets for throat inflammation caused by bacterial or viral infections.This study utilizes network pharmacology methods to analyze the therapeutic effects of KBDKFY on Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis,aiming to identify its active ingredients,action targets and related pathways through molecular docking.Additionally,it determines the affinity between the main active ingredient and the core target before conducting in vitro bacteriostatic tests.The analysis results show that KBDKFY contains multiple active ingredients and potential targets for treating Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis.KEGG enrichment analysis indicates that KBDKFY may have therapeutic effects on these conditions through pathways such as pathways in cancer,Kaposi sarcoma-associated herpesvirus infection,PI3K-Akt signaling pathway,and others.This provides a theoretical basis for further exploring pharmacological effects and clinical applications of KBDKFY.展开更多
Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy...Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).展开更多
In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount imp...In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount importance.These processes offer a distinctive opportunity to probe the gluon structure of nuclei across a broad range of Bjorken x,thereby enabling measurements of nuclear shadowing and facilitating the search for gluon saturation and color glass condensates.This study explores the potential of utilizing neutron tagging via the Coulomb excitation of nuclei to precisely determine the impact parameter for exclusive photoproduction in electron-ion collisions.By developing the equivalent photon approximation for fast electrons,this study incorporates a coordinate-space-dependent photon flux distribution to elucidate the relationship between the photon transverse momentum distribution and the collision impact parameter.Furthermore,the differential cross section for Coulomb excitation of nuclei is derived by leveraging the spatial information from the photon flux.Our calculations demonstrate that neutron tagging can significantly alter the impact parameter distributions,thereby providing a robust method for impact parameter manipulation in electron-ion collisions.This study provides valuable insights and strategies for exploring the impact parameter dependence of exclusive photoproduction,offering novel insights for experimental design and data analysis.Ultimately,it enhances our understanding of the gluon distribution within the nucleus.展开更多
As the integration of electronic components in high-performance servers increases,heat generation significantly impacts performance and raises failure rates.Therefore,heat dissipation has become a critical concern in ...As the integration of electronic components in high-performance servers increases,heat generation significantly impacts performance and raises failure rates.Therefore,heat dissipation has become a critical concern in electronic circuit design.This study uses numerical simulations to investigate the heat dissipation characteristics of electronic components in air-cooled servers.By adjusting airflow speed,heat sink configurations,and the arrangement of straight-fin heat sinks,we optimize heat dissipation performance and analyze the mechanisms at different airflow speeds.The results show that,at the same airflow speed,the temperature of the heat sink is lower than that of the electronic components,creating a temperature gradient that enhances heat transfer.Compared to a front-to-back arrangement of two straight-fin heat sinks,placing the heat sinks parallel to each other results in a lower maximum component temperature and better temperature uniformity.Heat sinks with fins significantly improve heat dissipation.The heat sink with semicylindrical fins on the rib surface provides the best cooling performance.Moreover,compared to natural convection,the maximum temperature of the electronic components decreases by 56.17%and 61%when the incoming flow velocity is 6 m/s with two parallel flat ribbed heat sinks and front-to-back arrangement,respectively.展开更多
基金funded by the Natural Science Foundation of Hunan Province(Grant No.2025JJ80352)the National Natural Science Foundation Project of China(Grant No.32271879).
文摘Detecting small forest fire targets in unmanned aerial vehicle(UAV)images is difficult,as flames typically cover only a very limited portion of the visual scene.This study proposes Context-guided Compact Lightweight Network(CCLNet),an end-to-end lightweight model designed to detect small forest fire targets while ensuring efficient inference on devices with constrained computational resources.CCLNet employs a three-stage network architecture.Its key components include three modules.C3F-Convolutional Gated Linear Unit(C3F-CGLU)performs selective local feature extraction while preserving fine-grained high-frequency flame details.Context-Guided Feature Fusion Module(CGFM)replaces plain concatenation with triplet-attention interactions to emphasize subtle flame patterns.Lightweight Shared Convolution with Separated Batch Normalization Detection(LSCSBD)reduces parameters through separated batch normalization while maintaining scale-specific statistics.We build TF-11K,an 11,139-image dataset combining 9139 self-collected UAV images from subtropical forests and 2000 re-annotated frames from the FLAME dataset.On TF-11K,CCLNet attains 85.8%mAP@0.5,45.5%mean Average Precision(mAP)@[0.5:0.95],87.4%precision,and 79.1%recall with 2.21 M parameters and 5.7 Giga Floating-point Operations Per Second(GFLOPs).The ablation study confirms that each module contributes to both accuracy and efficiency.Cross-dataset evaluation on DFS yields 77.5%mAP@0.5 and 42.3%mAP@[0.5:0.95],indicating good generalization to unseen scenes.These results suggest that CCLNet offers a practical balance between accuracy and speed for small-target forest fire monitoring with UAVs.
基金supported by the Fundamental Research Funds for the Central Universities(Nos.2232023D-01 and 2232023D-07)the Shanghai Science&Technology Committee(No.22ZR1403300)the National Natural Science Foundation of China(No.52372040).
文摘Metal-organic frameworks(MOFs)have attracted significant interest as self-templates and precursors for the synthesis of carbon-based composites aimed at electromagnetic wave(EMW)absorption.However,the utilization of high-temperature treatments has introduced uncertainties regarding the compositions and microstructures of resulting derivatives.Additionally,complete carbonization has led to diminished yields of the produced carbon composites,significantly limiting their practical applications.Consequently,the exploration of pristine MOF-based EMW absorbers presents an intriguing yet challenging endeavor,primarily due to inherently low electrical conductivity.In this study,we showcase the utilization of structurally robust Zr-MOFs as scaffolds to build highly conductive Zr-MOF/PPy composites via an inner-outer dual-modification approach,which involves the production of conducting polypyrrole(PPy)both within the confined nanoporous channels and the external surface of Zr-MOFs via post-synthetic modification.The interconnection of confined PPy and surface-lined PPy together leads to a consecutive and extensive conducting network to the maximum extent.This therefore entails outstanding conductivity up to~14.3 S cm^(-1) in Zr-MOF/PPy composites,which is approximately 1-2 orders of magnitude higher than that for conductive MOF nanocomposites constructed from either inner or outer modification.Benefiting from the strong and tunable conduction loss,as well as the induced dielectric polarization originated from the porous structures and MOF-polymer interfaces,Zr-MOF/PPy exhibits excellent microwave attenuation capabilities and a tunable absorption frequency range.Specifically,with only 15 wt.%loading,the minimum reflection loss(RLmin)can reach up to-67.4 dB,accompanied by an effective absorption bandwidth(EAB)extending to 6.74 GHz.Furthermore,the microwave absorption characteristics can be tailored from the C-band to the Ku-band by adjusting the loading of PPy.This work provides valuable insights into the fabrication of conductive MOF composites by presenting a straightforward pathway to enhance and reg-ulate electrical conduction in MOF-based nanocomposites,thus paving a way to facilely fabricate pristine MOF-based microwave absorbers.
文摘In order to further promote the standardization of diagnosis and treatment of gastrointestinal stromal tumor （GIST） in China, the members of Chinese Society of Clinical Oncology （CSCO） Expert Committee on GIST thoroughly discussed the key contents of the consensus guidelines, and voted on the controversial issue. In final, the Chinese consensus guidelines for the diagnosis and management of GIST （2017 edition） was formed on the basis of 2013 edition consensus guidelines, which is hereby announced. The consensus included the pathological diagnosis, recurrence risk classification evaluation, targeted agent therapy, surgery and principles of surveillance of GIST.
基金Supported by Sichuan Province Science and Technology Program,No.2024YFHZ0214 and No.2023YFS0299Chengdu Science and Technology Program,No.2024-YF05-01820-SN.
文摘BACKGROUND Dilated cardiomyopathy(DCM)is a common cause of systolic heart failure,and is the most prevalent type of non-ischemic cardiomyopathy.Primary hyperparathyroidism(PHPT)is characterized by hypercalcemia and excessive secretion of parathyroid hormone(PTH).Generally,PHPT is asymptomatic and is incidentally identified during routine laboratory assessments.CASE SUMMARY This case report details a 52-year-old man diagnosed with DCM and refractory hypercalcemia,who presented with clinical manifestations including dyspnea,recurrent anorexia,and abdominal distention.Laboratory investigations indicated an elevated serum PTH level,and the sestamibi scan suggested the presence of a parathyroid adenoma.Hence,the patient underwent a parathyroidectomy,which pathologically confirmed the diagnosis of a parathyroid adenoma.Postoperatively,the patient's hypercalcemia was corrected,the dimensions of the cardiac chambers were reduced,and there was a marked improvement in cardiac function.CONCLUSION Our findings emphasize the importance of PTH assessment in patients with DCM and concurrent hypercalcemia.
基金the technical support for Nano-X from Suzhou Institute of Nano-Tech and NanoBionics,Chinese Academy of Sciences(SINANO)supported by the National Key R&D Program of China(2021YFB3800300)+2 种基金the National Natural Science Foundation of China(22179059,22239002,92372201)the science and technology innovation fund for emission peak and carbon neutrality of Jiangsu province(BK20231512,BK20220034)the Key R&D project funded by department of science and technology of Jiangsu Province(BE2020003)。
文摘Aluminum(Al)exhibits excellent electrical conductivity,mechanical ductility,and good chemical compatibility with high-ionic-conductivity electrolytes.This makes it more suitable as an anode material for all-solid-state lithium batteries(ASSLBs)compared to the overly reactive metallic lithium anode and the mechanically weak silicon anode.This study finds that the pre-lithiated Al anode demonstrates outstanding interfacial stability with the Li_6PS_5Cl(LPSCl)electrolyte,maintaining stable cycling for over 1200 h under conditions of deep charge-discharge.This paper combines the pre-lithiated Al anode with a high-nickel cathode,LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2),paired with the highly ionic conductive LPSCl electrolyte,to design an ASSLB with high energy density and stability.Using anode pre-lithiation techniques,along with dual-reinforcement technology between the electrolyte and the cathode active material,the ASSLB achieves stable cycling for 1000 cycles at a 0.2C rate,with a capacity retention rate of up to 82.2%.At a critical negative-to-positive ratio of 1.1,the battery's specific energy reaches up to 375 Wh kg^(-1),and it maintains over 85.9%of its capacity after 100 charge-discharge cycles.This work provides a new approach and an excellent solution for developing low-cost,high-stability all-solid-state batteries.
基金supported by the National College Student Innovation and Entrepreneurship Project.
文摘Hyperuricemia(HUA)refers to a condition where fasting serum uric acid levels exceed 420μmol/L in men and 350μmol/L in women,affecting 17.4%of China’s general population,showing increasing prevalence among younger individuals.Luteolin,a common flavonoid compound,exhibits multiple biological effects,including inhibition of tumor proliferation and inflammatory responses.It also suppresses the activity of urate transporter 1(URAT1),promoting uric acid excretion.This study is the first to integrate network toxicology and network pharmacology approaches to systematically analyze the multi-target mechanisms of adenine-induced HUA and luteolin-treated HUA,with molecular docking validation of interaction targets.We constructed compound-pathway-intersection gene networks and a dual-group PPI network to analyze the mechanisms of adenine-induced HUA and luteolin-treated HUA.The dual-group PPI network identified 7 shared targets,namely XDH,PYGL,IL10,PPARG,TNF,VEGFA,and MAOA,involving core intersecting pathways such as purine-xanthine metabolism and insulin resistance.Luteolin may activate PPARG to regulate inflammation and uric acid excretion modules in the adenine network.GO-KEGG analysis indicates that intersection genes for adenine pathogenesis involve diverse biological processes,cellular components,and molecular functions,with core target KEGG analysis revealing 15 signaling pathways.Luteolin’s therapeutic targets are associated with more entries,and its core target KEGG analysis identified 46 signaling pathways.Molecular docking shows TNF,PPARG,and PYGL bind to both luteolin and adenine with negative binding energies,and luteolin’s binding energies are all below 5 kJ/mol,confirming stable binding.Luteolin’s anti-HUA mechanism is characterized by inhibition of production,promotion of excretion,anti-inflammation and metabolic regulation,but interactions with gut microbiota metabolites require further study.
基金supported by Scientific Research Fund Project of Education Department of Liaoning Province(LJKZ0960)Science Foundation of Shenyang Pharmaceutical University(GGJJ2021105)National College Student Innovation and Entrepreneurship Project.
文摘KangBingDuKouFuYe(KBDKFY)is widely used to treat influenza,upper respiratory tract infections,mumps and other diseases.Due to their diverse active ingredients,it is believed that they may have excellent anti-inflammatory,antibacterial and antiviral effects.Therefore,we believe they may have multiple therapeutic targets for throat inflammation caused by bacterial or viral infections.This study utilizes network pharmacology methods to analyze the therapeutic effects of KBDKFY on Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis,aiming to identify its active ingredients,action targets and related pathways through molecular docking.Additionally,it determines the affinity between the main active ingredient and the core target before conducting in vitro bacteriostatic tests.The analysis results show that KBDKFY contains multiple active ingredients and potential targets for treating Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis.KEGG enrichment analysis indicates that KBDKFY may have therapeutic effects on these conditions through pathways such as pathways in cancer,Kaposi sarcoma-associated herpesvirus infection,PI3K-Akt signaling pathway,and others.This provides a theoretical basis for further exploring pharmacological effects and clinical applications of KBDKFY.
基金supported by the National Key Research and Development Program of China(No.2022YFA1602200)the National Natural Science Foundation of China(Nos.12341501 and 12405174)the Hefei Comprehensive National Science Center for the strong support on the STCF key technology research project.
文摘Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×10^(34)cm^(−2)s^(−1)that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).
基金supported in part by the National Key Research and Development Program of China under Contract No.2022YFA1604900the National Natural Science Foundation of China(NSFC)under Contract No.12175223 and 12005220+1 种基金W.Zha is supported by Anhui Provincial Natural Science Foundation No.2208085J23Youth Innovation Promotion Association of Chinese Academy of Science.
文摘In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount importance.These processes offer a distinctive opportunity to probe the gluon structure of nuclei across a broad range of Bjorken x,thereby enabling measurements of nuclear shadowing and facilitating the search for gluon saturation and color glass condensates.This study explores the potential of utilizing neutron tagging via the Coulomb excitation of nuclei to precisely determine the impact parameter for exclusive photoproduction in electron-ion collisions.By developing the equivalent photon approximation for fast electrons,this study incorporates a coordinate-space-dependent photon flux distribution to elucidate the relationship between the photon transverse momentum distribution and the collision impact parameter.Furthermore,the differential cross section for Coulomb excitation of nuclei is derived by leveraging the spatial information from the photon flux.Our calculations demonstrate that neutron tagging can significantly alter the impact parameter distributions,thereby providing a robust method for impact parameter manipulation in electron-ion collisions.This study provides valuable insights and strategies for exploring the impact parameter dependence of exclusive photoproduction,offering novel insights for experimental design and data analysis.Ultimately,it enhances our understanding of the gluon distribution within the nucleus.
基金supported by the key technology project of China Southern Power Grid Corporation(GZKJXM20240009).
文摘As the integration of electronic components in high-performance servers increases,heat generation significantly impacts performance and raises failure rates.Therefore,heat dissipation has become a critical concern in electronic circuit design.This study uses numerical simulations to investigate the heat dissipation characteristics of electronic components in air-cooled servers.By adjusting airflow speed,heat sink configurations,and the arrangement of straight-fin heat sinks,we optimize heat dissipation performance and analyze the mechanisms at different airflow speeds.The results show that,at the same airflow speed,the temperature of the heat sink is lower than that of the electronic components,creating a temperature gradient that enhances heat transfer.Compared to a front-to-back arrangement of two straight-fin heat sinks,placing the heat sinks parallel to each other results in a lower maximum component temperature and better temperature uniformity.Heat sinks with fins significantly improve heat dissipation.The heat sink with semicylindrical fins on the rib surface provides the best cooling performance.Moreover,compared to natural convection,the maximum temperature of the electronic components decreases by 56.17%and 61%when the incoming flow velocity is 6 m/s with two parallel flat ribbed heat sinks and front-to-back arrangement,respectively.
