The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjian...The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjiang,China.Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S.pneumoniae carriage.展开更多
The aim of this study was to evaluate the diagnostic value of the cerebrospinal fluid（CSF） T‐SPOT.TB test for the diagnosis of TB meningitis（TBM）. A retrospective analysis of 96 patients with manifested meningiti...The aim of this study was to evaluate the diagnostic value of the cerebrospinal fluid（CSF） T‐SPOT.TB test for the diagnosis of TB meningitis（TBM）. A retrospective analysis of 96 patients with manifested meningitis was conducted; T‐SPOT.TB test was performed for diagnosing TBM to determine the diagnostic sensitivity, specificity, positive predictive value（PPV）, and negative predictive value（NPV）. A receiver operating characteristic（ROC） curve was also drawn to assess the diagnostic accuracy. The sensitivity, specificity, PPV, and NPV of CSF T‐SPOT.TB test were 97.8%, 78.0%, 80.3%, and 97.5%, respectively, for 52 patients（54.2%） of the 96 enrolled patients. The area under the curve（AUC） was 0.910, and the sensitivities of CSF T‐SPOT.TB for patients with stages I, II, and III of TBM were 96.7%, 97.2%, and 98.9%, respectively. CSF T‐SPOT.TB test is a rapid and accurate diagnostic method with higher sensitivity and specificity for diagnosing TBM.展开更多
[Objective] The aim was to analyze one cold wave weather process in Chengdu in March in 2010.[Method] Based on the NCEP 1°×1° 6 h interval reanalysis data and daily observation data,using synoptic analy...[Objective] The aim was to analyze one cold wave weather process in Chengdu in March in 2010.[Method] Based on the NCEP 1°×1° 6 h interval reanalysis data and daily observation data,using synoptic analysis and diagnosis methods,and combining with the cold wave forecast index in spring of Sichuan,a cold wave event covering the whole region between March 21 and 24,2010 was analyzed from the aspects of circulation background,influencing weather systems and weather causation.[Result] Results showed that the 500 high-altitude cold vortex,700-850 hPa low layer shear,and ground cold front were the main systems that influenced this cold wave;there was a ridge from Lake Balkhash across Lake Baikal at 500 hPa.The early stage of the process was controlled by the high pressure ridge and the temperature was increasing obviously.The daily mean temperature was high.The range of cold high pressure was large and the central intensity was 1 043.0 hPa;the cold air was strong and deep which was in accordance with the strong surface temperature reduction center.The strong north airstream of Lake Balkhash to Lake Baikal,ground cold high pressure center intensity changes,north and south ocean pressure and temperature differences,850 hPa temperature changes,cold advection movement route and intensity were considered as reference factors for the forecast of cold wave intensity.[Conclusion] The study provided theoretical basis for improving the forecast ability of cold wave weather.展开更多
Studying the dynamics of plant populations is crucial to the conservation and management of endangered plants.The diameter at breast height(DBH),tree height,crown width,and environmental factors of a total of 15 plots...Studying the dynamics of plant populations is crucial to the conservation and management of endangered plants.The diameter at breast height(DBH),tree height,crown width,and environmental factors of a total of 15 plots in five populations in Guizhou Province,China were measured in this study.The method of substituting diameter at breast height for age was used to divide the population into 7 age classes.The age structure,static life table,and relationship between the population characteristics and environmental factors of the Litsea coreana Levl.var.sinensis population were studied.Moreover,the time series model was used to predict the population dynamics.Results showed that the age structure of population in Zhengan County(Population ZA)had an inverted Jshape with abundant seedlings and insufficient middle-aged and elderly individuals.The age structures of populations in Daozhen County(Population DZ),Kaiyang County(KY),Meitan County(Population MT),and Xishui County(Population XS)were spindle-shaped with few young individuals and many middle-aged and elderly individuals.The mortality rate of each population fluctuated with the increase in age class,and the populations were extremely unstable.The survival curve was close to the Deevey III type,and the degree of deviation was related to the lack of young individuals.After the age stages II,IV,and VI,the number of aged plants in the different populations initially increased then decreased,and population stability was difficult to maintain.Redundancy analysis showed that the DBH,tree height and crown width of the population decreased with the increase of annual mean temperature,and the population density was restricted by soil nutrient conditions to a certain extent.The results of this work provide scientific basis for the conservation and sustainable utilization of natural populations of L.coreana var.sinensis in Guizhou Province,China.展开更多
Magnetic field was introduced in laser melting deposition to reduce the pores in workpieces.Finite 3-D model of the coil-deposition layer-substrate was established.Simulation results show that the electromagnetic forc...Magnetic field was introduced in laser melting deposition to reduce the pores in workpieces.Finite 3-D model of the coil-deposition layer-substrate was established.Simulation results show that the electromagnetic force in deposition layer mainly concentrates in the projection area of the coil.Axial electromagnetic force shows repulsion in one cycle.The experimental results indicate that the magnetic field is beneficial for grain refinement,microhardness increasement and decline of quantities and average sizes of pores.展开更多
This thesis probes into the current situation of host social media usage and intercultural adaptation of preparatory international students in China. Study covered 208 preparatory international students in total was c...This thesis probes into the current situation of host social media usage and intercultural adaptation of preparatory international students in China. Study covered 208 preparatory international students in total was conducted, with subject observation, structured interview, and questionnaire, in Shandong University, which is considered as one of the most representative institutions providing high-level preparatory education for international students in China. Field data collected were analyzed descriptively in the form of frequencies, tables, and percentages. Taken all that have been analyzed in this thesis, findings strongly suggest that the main factors influencing international students’ intercultural adaptability include host social media usage, intercultural experience, mandarin level, and cultural distance. Results also indicate significant correlation between host social media usage and intercultural adaptation: students who frequently use host social media to chat with Chinese perform better at intercultural adaptation;those who are more dependent and satisfied with host social media are more adaptive as well, the same goes to students who use host social media more frequently to get information or socialize. Consequently, this study suggests necessary promotion of host social media for international students in China.展开更多
Objective:To explore the relationship between the expression of miR-29c and clinicopathological characteristics of gastric cancer and predict the biological functions of target genes of miR-29c.Methods:The expression ...Objective:To explore the relationship between the expression of miR-29c and clinicopathological characteristics of gastric cancer and predict the biological functions of target genes of miR-29c.Methods:The expression and clinical data of microRNA of gastric cancer were downloaded from The Cancer Genome Atlas(TCGA)to analyze the expression of miR-29c in gastric cancer tissues and normal gastric mucosal tissues.Paraffin specimens of gastric cancer and normal tissues were collected to make tissue microarray.The expression of miR-29c in gastric cancer tissues and normal tissues were detected by miRNAscope technique.The relationship between the expression of miR-29c and clinicopathological characteristics of gastric cancer was analyzed by chi-square test.Target genes of miR-29c were predicted by TargetScan,Pictar,miRTarbase and Starbase databases,and enrichment analysis were performed on potential target genens.Results:TCGA analysis showed that the expression of miR-29c was significantly lower in gastric cancer tissue(n=434)than normal tissues(n=41,P<0.001).miRNAscope analysis showed that the expression of miR-29c was significantly lower in gastric cancer tissue than normal tissues(P<0.001),and was significantly associated with TNM staging,lymph node metastasis and histological type of gastric cancer patients(P<0.05).Database predicted 18 potential target genes that were enriched in DNA methyltransferase activity and cancer-associated miRNA signal pathways.Conclusion:miR-29c was expressed at a low level in gastric cancer tissue and associated with TNM staging,lymph node metastasis and histological type,and could become a potential prognosis marker of gastric cancer and a new target of molecular treatment.展开更多
Rhynchaenus empopulifolis is a defoliator harming poplar,and its occurrence is reported in Tai’an area for the first time.Through indoor rearing and forest investigation,the morphological,biological and damage charac...Rhynchaenus empopulifolis is a defoliator harming poplar,and its occurrence is reported in Tai’an area for the first time.Through indoor rearing and forest investigation,the morphological,biological and damage characteristics of R.empopulifolis in Tai’an were observed,and color pictures of each instar and local characteristics of adult as well as damage symptoms were provided,in order to lay a theoretical basis for rapid identification and precise control of R.empopulifolis.展开更多
基金supported by grants from the State Key Laboratory of Infectious Disease Prevention and Control[2015SKLID502]the National Natural Science Foundation of China[81602903]Youth Science and Technology Talented Project of special scientific research in health and family planning commission in Xinjiang Uygur Autonomous Region[2016Y25]
文摘The carriage rate and serotype distribution of Streptococcus pneumoniae（S.pneumoniae）in a healthy population in China remains unclear.In this study,we collected the oropharyngeal swabs from513 individuals in Xinjiang,China.Real-time PCR targeting the lytA gene and 12 serotypes were assessed to identify S.pneumoniae carriage.
文摘The aim of this study was to evaluate the diagnostic value of the cerebrospinal fluid（CSF） T‐SPOT.TB test for the diagnosis of TB meningitis（TBM）. A retrospective analysis of 96 patients with manifested meningitis was conducted; T‐SPOT.TB test was performed for diagnosing TBM to determine the diagnostic sensitivity, specificity, positive predictive value（PPV）, and negative predictive value（NPV）. A receiver operating characteristic（ROC） curve was also drawn to assess the diagnostic accuracy. The sensitivity, specificity, PPV, and NPV of CSF T‐SPOT.TB test were 97.8%, 78.0%, 80.3%, and 97.5%, respectively, for 52 patients（54.2%） of the 96 enrolled patients. The area under the curve（AUC） was 0.910, and the sensitivities of CSF T‐SPOT.TB for patients with stages I, II, and III of TBM were 96.7%, 97.2%, and 98.9%, respectively. CSF T‐SPOT.TB test is a rapid and accurate diagnostic method with higher sensitivity and specificity for diagnosing TBM.
文摘[Objective] The aim was to analyze one cold wave weather process in Chengdu in March in 2010.[Method] Based on the NCEP 1°×1° 6 h interval reanalysis data and daily observation data,using synoptic analysis and diagnosis methods,and combining with the cold wave forecast index in spring of Sichuan,a cold wave event covering the whole region between March 21 and 24,2010 was analyzed from the aspects of circulation background,influencing weather systems and weather causation.[Result] Results showed that the 500 high-altitude cold vortex,700-850 hPa low layer shear,and ground cold front were the main systems that influenced this cold wave;there was a ridge from Lake Balkhash across Lake Baikal at 500 hPa.The early stage of the process was controlled by the high pressure ridge and the temperature was increasing obviously.The daily mean temperature was high.The range of cold high pressure was large and the central intensity was 1 043.0 hPa;the cold air was strong and deep which was in accordance with the strong surface temperature reduction center.The strong north airstream of Lake Balkhash to Lake Baikal,ground cold high pressure center intensity changes,north and south ocean pressure and temperature differences,850 hPa temperature changes,cold advection movement route and intensity were considered as reference factors for the forecast of cold wave intensity.[Conclusion] The study provided theoretical basis for improving the forecast ability of cold wave weather.
基金supported by the National Natural Science Foundation of China(32060349)China Scholarship Council([2021]15)。
文摘Studying the dynamics of plant populations is crucial to the conservation and management of endangered plants.The diameter at breast height(DBH),tree height,crown width,and environmental factors of a total of 15 plots in five populations in Guizhou Province,China were measured in this study.The method of substituting diameter at breast height for age was used to divide the population into 7 age classes.The age structure,static life table,and relationship between the population characteristics and environmental factors of the Litsea coreana Levl.var.sinensis population were studied.Moreover,the time series model was used to predict the population dynamics.Results showed that the age structure of population in Zhengan County(Population ZA)had an inverted Jshape with abundant seedlings and insufficient middle-aged and elderly individuals.The age structures of populations in Daozhen County(Population DZ),Kaiyang County(KY),Meitan County(Population MT),and Xishui County(Population XS)were spindle-shaped with few young individuals and many middle-aged and elderly individuals.The mortality rate of each population fluctuated with the increase in age class,and the populations were extremely unstable.The survival curve was close to the Deevey III type,and the degree of deviation was related to the lack of young individuals.After the age stages II,IV,and VI,the number of aged plants in the different populations initially increased then decreased,and population stability was difficult to maintain.Redundancy analysis showed that the DBH,tree height and crown width of the population decreased with the increase of annual mean temperature,and the population density was restricted by soil nutrient conditions to a certain extent.The results of this work provide scientific basis for the conservation and sustainable utilization of natural populations of L.coreana var.sinensis in Guizhou Province,China.
基金supported by the National Science Foundation of China(No.51475238)the Jiangsu Science and Technology Support Program(No.BE2014009-1)the Jiangsu Provincial Key Research and Development Plan (Nos.BE201561,BE201603-3)
文摘Magnetic field was introduced in laser melting deposition to reduce the pores in workpieces.Finite 3-D model of the coil-deposition layer-substrate was established.Simulation results show that the electromagnetic force in deposition layer mainly concentrates in the projection area of the coil.Axial electromagnetic force shows repulsion in one cycle.The experimental results indicate that the magnetic field is beneficial for grain refinement,microhardness increasement and decline of quantities and average sizes of pores.
文摘This thesis probes into the current situation of host social media usage and intercultural adaptation of preparatory international students in China. Study covered 208 preparatory international students in total was conducted, with subject observation, structured interview, and questionnaire, in Shandong University, which is considered as one of the most representative institutions providing high-level preparatory education for international students in China. Field data collected were analyzed descriptively in the form of frequencies, tables, and percentages. Taken all that have been analyzed in this thesis, findings strongly suggest that the main factors influencing international students’ intercultural adaptability include host social media usage, intercultural experience, mandarin level, and cultural distance. Results also indicate significant correlation between host social media usage and intercultural adaptation: students who frequently use host social media to chat with Chinese perform better at intercultural adaptation;those who are more dependent and satisfied with host social media are more adaptive as well, the same goes to students who use host social media more frequently to get information or socialize. Consequently, this study suggests necessary promotion of host social media for international students in China.
基金National Natural Science Foundation of China(82060437)。
文摘Objective:To explore the relationship between the expression of miR-29c and clinicopathological characteristics of gastric cancer and predict the biological functions of target genes of miR-29c.Methods:The expression and clinical data of microRNA of gastric cancer were downloaded from The Cancer Genome Atlas(TCGA)to analyze the expression of miR-29c in gastric cancer tissues and normal gastric mucosal tissues.Paraffin specimens of gastric cancer and normal tissues were collected to make tissue microarray.The expression of miR-29c in gastric cancer tissues and normal tissues were detected by miRNAscope technique.The relationship between the expression of miR-29c and clinicopathological characteristics of gastric cancer was analyzed by chi-square test.Target genes of miR-29c were predicted by TargetScan,Pictar,miRTarbase and Starbase databases,and enrichment analysis were performed on potential target genens.Results:TCGA analysis showed that the expression of miR-29c was significantly lower in gastric cancer tissue(n=434)than normal tissues(n=41,P<0.001).miRNAscope analysis showed that the expression of miR-29c was significantly lower in gastric cancer tissue than normal tissues(P<0.001),and was significantly associated with TNM staging,lymph node metastasis and histological type of gastric cancer patients(P<0.05).Database predicted 18 potential target genes that were enriched in DNA methyltransferase activity and cancer-associated miRNA signal pathways.Conclusion:miR-29c was expressed at a low level in gastric cancer tissue and associated with TNM staging,lymph node metastasis and histological type,and could become a potential prognosis marker of gastric cancer and a new target of molecular treatment.
文摘Rhynchaenus empopulifolis is a defoliator harming poplar,and its occurrence is reported in Tai’an area for the first time.Through indoor rearing and forest investigation,the morphological,biological and damage characteristics of R.empopulifolis in Tai’an were observed,and color pictures of each instar and local characteristics of adult as well as damage symptoms were provided,in order to lay a theoretical basis for rapid identification and precise control of R.empopulifolis.
