针对频率分集多输入多输出(Multiple-Input Multiple-Output with Frequency Diverse Array,FDA-MIMO)雷达在采用常规线性频率间隔的情况下,出现的距离维栅瓣与距离维主瓣宽度的矛盾问题,提出了一种基于子阵的FDA-MIMO雷达去栅瓣方法,...针对频率分集多输入多输出(Multiple-Input Multiple-Output with Frequency Diverse Array,FDA-MIMO)雷达在采用常规线性频率间隔的情况下,出现的距离维栅瓣与距离维主瓣宽度的矛盾问题,提出了一种基于子阵的FDA-MIMO雷达去栅瓣方法,推导出基于子阵的FDA-MIMO雷达闭合方向图表达式,并分析了FDA-MIMO雷达采用子阵去除栅瓣和提高距离维分辨率的原理。仿真结果表明,与通过限定频率间隔选取范围去除距离维栅瓣的常规方法相比,当子阵采用互质大频率间隔时,FDA-MIMO雷达形成的方向图不仅去除了距离维栅瓣,且距离维主瓣宽度更窄,距离维分辨率更高。展开更多
A highly efficient method to get 3-and 6-modified mannose/ahrose derivatives for oligosaccharide synthesis is described. All the compounds were obtained exclusively with the combinations of 3-and/or 6-hydroxyl protect...A highly efficient method to get 3-and 6-modified mannose/ahrose derivatives for oligosaccharide synthesis is described. All the compounds were obtained exclusively with the combinations of 3-and/or 6-hydroxyl protection and/or activation( including the configuration conversion of 3-carbon atom).展开更多
Deep learning based recommendation methods, such as the recurrent neural network based recommendation method(RNNRec) and the gated recurrent unit(GRU) based recommendation method(GRURec), are proposed to solve the pro...Deep learning based recommendation methods, such as the recurrent neural network based recommendation method(RNNRec) and the gated recurrent unit(GRU) based recommendation method(GRURec), are proposed to solve the problem of time heterogeneous feedback recommendation. These methods out-perform several state-of-the-art methods. However, in RNNRec and GRURec, action vectors and item vectors are shared among users. The different meanings of the same action for different users are not considered. Similarly, different user preference for the same item is also ignored. To address this problem, the models of RNNRec and GRURec are modified in this paper. In the proposed methods, action vectors and item vectors are transformed into the user space for each user firstly, and then the transformed vectors are fed into the original neural networks of RNNRec and GRURec. The transformed action vectors and item vectors represent the user specified meaning of actions and the preference for items, which makes the proposed method obtain more accurate recommendation results. The experimental results on two real-life datasets indicate that the proposed method outperforms RNNRec and GRURec as well as other state-of-the-art approaches in most cases.展开更多
The organization of the microtubule cytoskeleton is critical for cell and organ morphogenesis.The evolutionarily conserved microtubule-severing enzyme KATANIN plays critical roles in microtubule organization in the pl...The organization of the microtubule cytoskeleton is critical for cell and organ morphogenesis.The evolutionarily conserved microtubule-severing enzyme KATANIN plays critical roles in microtubule organization in the plant and animal kingdoms.We previously used conical cell of Arabidopsis thaliana petals as a model system to investigate cortical microtubule organization and cell morphogenesis and determined that KATANIN promotes the formation of circumferential cortical microtubule arrays in conical cells.Here,we demonstrate that the conserved protein phosphatase PP2A interacts with and dephosphorylates KATANIN to promote the formation of circumferential cortical microtubule arrays in conical cells.KATANIN undergoes cycles of phosphorylation and dephosphorylation.Using co-immunoprecipitation coupled with mass spectrometry,we identified PP2A subunits as KATANIN-interacting proteins.Further biochemical studies showed that PP2 A interacts with and dephosphorylates KATANIN to stabilize its cellular abundance.Similar to the katanin mutant,mutants for genes encoding PP2A subunits showed disordered cortical microtubule arrays and defective conical cell shape.Taken together,these findings identify PP2A as a regulator of conical cell shape and suggest that PP2A mediates KATANIN phospho-regulation during plant cell morphogenesis.展开更多
文摘针对频率分集多输入多输出(Multiple-Input Multiple-Output with Frequency Diverse Array,FDA-MIMO)雷达在采用常规线性频率间隔的情况下,出现的距离维栅瓣与距离维主瓣宽度的矛盾问题,提出了一种基于子阵的FDA-MIMO雷达去栅瓣方法,推导出基于子阵的FDA-MIMO雷达闭合方向图表达式,并分析了FDA-MIMO雷达采用子阵去除栅瓣和提高距离维分辨率的原理。仿真结果表明,与通过限定频率间隔选取范围去除距离维栅瓣的常规方法相比,当子阵采用互质大频率间隔时,FDA-MIMO雷达形成的方向图不仅去除了距离维栅瓣,且距离维主瓣宽度更窄,距离维分辨率更高。
文摘A highly efficient method to get 3-and 6-modified mannose/ahrose derivatives for oligosaccharide synthesis is described. All the compounds were obtained exclusively with the combinations of 3-and/or 6-hydroxyl protection and/or activation( including the configuration conversion of 3-carbon atom).
基金supported by the National Natural Science Foundation of China(61403350)。
文摘Deep learning based recommendation methods, such as the recurrent neural network based recommendation method(RNNRec) and the gated recurrent unit(GRU) based recommendation method(GRURec), are proposed to solve the problem of time heterogeneous feedback recommendation. These methods out-perform several state-of-the-art methods. However, in RNNRec and GRURec, action vectors and item vectors are shared among users. The different meanings of the same action for different users are not considered. Similarly, different user preference for the same item is also ignored. To address this problem, the models of RNNRec and GRURec are modified in this paper. In the proposed methods, action vectors and item vectors are transformed into the user space for each user firstly, and then the transformed vectors are fed into the original neural networks of RNNRec and GRURec. The transformed action vectors and item vectors represent the user specified meaning of actions and the preference for items, which makes the proposed method obtain more accurate recommendation results. The experimental results on two real-life datasets indicate that the proposed method outperforms RNNRec and GRURec as well as other state-of-the-art approaches in most cases.
基金financially supported by grants from the Natural Science Foundation of Fujian Province(2018J01600)the National Natural Science Foundation of China(31822003,31771344,and 31500160)。
文摘The organization of the microtubule cytoskeleton is critical for cell and organ morphogenesis.The evolutionarily conserved microtubule-severing enzyme KATANIN plays critical roles in microtubule organization in the plant and animal kingdoms.We previously used conical cell of Arabidopsis thaliana petals as a model system to investigate cortical microtubule organization and cell morphogenesis and determined that KATANIN promotes the formation of circumferential cortical microtubule arrays in conical cells.Here,we demonstrate that the conserved protein phosphatase PP2A interacts with and dephosphorylates KATANIN to promote the formation of circumferential cortical microtubule arrays in conical cells.KATANIN undergoes cycles of phosphorylation and dephosphorylation.Using co-immunoprecipitation coupled with mass spectrometry,we identified PP2A subunits as KATANIN-interacting proteins.Further biochemical studies showed that PP2 A interacts with and dephosphorylates KATANIN to stabilize its cellular abundance.Similar to the katanin mutant,mutants for genes encoding PP2A subunits showed disordered cortical microtubule arrays and defective conical cell shape.Taken together,these findings identify PP2A as a regulator of conical cell shape and suggest that PP2A mediates KATANIN phospho-regulation during plant cell morphogenesis.