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自身免疫性聋的分子作用机制
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作者 T.J.Yoo x.du +2 位作者 S.S.Kwon 宋鹏 龚树生 《国外医学(耳鼻咽喉科学分册)》 2004年第6期358-361,共4页
本文回顾分析了Ⅱ型胶原、Ⅸ型胶原、内耳膜迷路 30ku蛋白、层粘连蛋白、 6 8ku蛋白、P0蛋白、Raf 1蛋白、β 微管蛋白等几种在自身免疫性耳聋和梅尼埃病中的自身抗原及其致聋的分子机制。
关键词 自身免疫性聋 分子作用机制 Ⅱ型胶原、Ⅸ型胶原 层粘连蛋白 内耳膜迷路
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Periodically poled aluminum scandium nitride bulk acoustic wave resonators and filters for communications in the 6G era
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作者 Izhar M.M.A.Fiagbenu +9 位作者 S.Yao x.du P.Musavigharavi Y.Deng J.Leathersich C.Moe A.Kochhar E.A.Stach R.Vetury R.H.Olsson 《Microsystems & Nanoengineering》 2025年第1期265-275,共11页
Bulk Acoustic Wave(BAW)filters find applications in radio frequency(RF)communication systems for Wi-Fi,3G,4G,and 5G networks.In the beyond-5G(potential 6G)era,high-frequency bands(>8 GHz)are expected to require res... Bulk Acoustic Wave(BAW)filters find applications in radio frequency(RF)communication systems for Wi-Fi,3G,4G,and 5G networks.In the beyond-5G(potential 6G)era,high-frequency bands(>8 GHz)are expected to require resonators with high-quality factor(Q)and electromechanical coupling(k_(t)^(2))to form filters with low insertion loss and high selectivity.However,both the Q and k_(t)^(2)of resonator devices formed in traditional uniform polarization piezoelectric films of aluminum nitride(AlN)and aluminum scandium nitride(AlScN)decrease when scaled beyond 8 GHz.In this work,we utilized 4-layer AlScN periodically poled piezoelectric films(P3F)to construct high-frequency(~17–18 GHz)resonators and filters.The resonator performance is studied over a range of device geometries,with the best resonator achieving a k_(t)^(2)of 11.8%and a Qp of 236.6 at the parallel resonance frequency(f_(p))of 17.9 GHz.These resulting figures-of-merit are(FoM_(1)=k_(t)^(2)Qp and FoM_(2)=f_(p)FoM_(1)×10^(-9))27.9 and 500,respectively.These and the k_(t)^(2)are significantly higher than previously reported AlN/AlScN-based resonators operating at similar frequencies.Fabricated 3-element and 6-element filters formed from these resonators demonstrated low insertion losses(IL)of 1.86 and 3.25 dB,and−3 dB bandwidths(BW)of 680 MHz(fractional BW of 3.9%)and 590 MHz(fractional BW of 3.3%)at a~17.4 GHz center frequency.The 3-element and 6-element filters achieved excellent linearity with in-band input third-order intercept point(IIP3)values of+36 and+40 dBm,respectively,which are significantly higher than previously reported acoustic filters operating at similar frequencies. 展开更多
关键词 Periodically Poled FILTERS uniform polarization piezoelectric films electromechanical coupling k t Aluminum Scandium Nitride High Frequency Communication Bulk Acoustic Wave Resonators aluminum scandium n
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Inside-Out 3D Reversible Ion-Triggered Shape-Morphing Hydrogels 被引量:13
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作者 x.du H.Cui +3 位作者 Q.Zhao J.Wang H.Chen Y.Wang 《Research》 EI CAS 2019年第1期1237-1248,共12页
Shape morphing is a critical aptitude for the survival of organisms and is determined by anisotropic tissue composition and directional orientation of micro-and nanostructures within cell walls,resulting in diferent s... Shape morphing is a critical aptitude for the survival of organisms and is determined by anisotropic tissue composition and directional orientation of micro-and nanostructures within cell walls,resulting in diferent swelling behaviors.Recent eforts have been dedicated to mimicking the behaviors that nature has perfected over billions of years.We present a robust strategy for preparing 3D periodically patterned single-component sodium alginate hydrogel sheets cross-linked with Ca^(2+)ions,which can reversibly deform and be retained into various desirable inside-out shapes as triggered by biocompatible ions(Na^(+)/Ca^(2+)).By changing the orientations of the patterned microchannels or triggering with Na^(+)/Ca^(2+)ions,various 3D twisting,tubular,and plantinspired architectures can be facilely programmed.Not only can the transformation recover their initial shapes reversibly,but also it can keep the designated shapes without continuous stimuli.Tese inside-out 3D reversible ion-triggered hydrogel transformations shall inspire more attractive applications in tissue engineering,biomedical devices,and sof robotics felds. 展开更多
关键词 SWELLING PREPARING ATTRACTIVE
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