Stroke is one of the leading causes of death and long-term disability worldwide,severely affecting patients'quality of life and socio-economic development.In recent years,with advancements in neuroscience,research...Stroke is one of the leading causes of death and long-term disability worldwide,severely affecting patients'quality of life and socio-economic development.In recent years,with advancements in neuroscience,researchers have gradually recognized that neuroinflammation plays critical roles in the neurorestoration after stroke.1 Understanding the molecular mechanisms of these processes helps reveal the complex pathophysiological changes following stroke and provides new perspectives for developing effective therapeutic strategies.2 This editorial aims to explore the molecular mechanisms of neuroinflammation and neurorestoration after stroke and review current therapeutic strategies to provide theoretical support for clinical interventions.展开更多
基金supported by grants from the National Natural Science Foundation of China(81960234,82071331)National Key Research and Development Program of China(2018YFC1312200)+3 种基金Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(GZC20232401)Henan Province Medical Science and Technology Research Program(SBGJ202403031)Hunan Provincial Natural Science Foundation(2023JJ40572)Canadian Institutes of Health Research(VWY)。
文摘Stroke is one of the leading causes of death and long-term disability worldwide,severely affecting patients'quality of life and socio-economic development.In recent years,with advancements in neuroscience,researchers have gradually recognized that neuroinflammation plays critical roles in the neurorestoration after stroke.1 Understanding the molecular mechanisms of these processes helps reveal the complex pathophysiological changes following stroke and provides new perspectives for developing effective therapeutic strategies.2 This editorial aims to explore the molecular mechanisms of neuroinflammation and neurorestoration after stroke and review current therapeutic strategies to provide theoretical support for clinical interventions.