Edible-medicinal plants play an important role in promoting the pharmaceutical industry and the construction of beautiful countryside.With the development trend of industry promoting rural revitalization,the applicati...Edible-medicinal plants play an important role in promoting the pharmaceutical industry and the construction of beautiful countryside.With the development trend of industry promoting rural revitalization,the application of edible-medicinal plants in landscaping is also receiving more and more attention.The present study elaborated the role of edible-medicinal plants and their application principles in landscaping.It stated that the application of edible-medicinal plants in landscaping can improve the preservation and application technology of characteristic edible-medicinal plants in the area of south of the Five Ridges,ensure the sustainable development of edible-medicinal plants and promote the effective connection between poverty alleviation and rural revitalization.展开更多
The functions of medicinal botanical gardens are introduced firstly,and then the application status and planning principles of medicinal botanical gardens based on the theme of science popularization education are ana...The functions of medicinal botanical gardens are introduced firstly,and then the application status and planning principles of medicinal botanical gardens based on the theme of science popularization education are analyzed.Moreover,a typical application case is analyzed and summarized.Constructing a scientific medicinal botanical garden is conducive to increasing people's understanding of medicinal plants,and also meets the requirements of current national policies,thereby generating greater economic and social benefits.展开更多
The use of artificial sweeteners is becoming increasingly common.High-fructose corn syrup(HFCS)and aspartame are the two most commonly used sweeteners.It is reported that their consumption was associated with the impa...The use of artificial sweeteners is becoming increasingly common.High-fructose corn syrup(HFCS)and aspartame are the two most commonly used sweeteners.It is reported that their consumption was associated with the impairment of cognitive function.However,the specific mechanism whereby HFCS and aspartame diets influence cognitive function is still unclear.Here,we administered 20%HFCS and 50 mg/kg aspartame in drinking water to establish a dietary intervention,and assessed mouse cognitive function using the novel object recognition(NOR)experiment.Results showed that the cognitive function of the mice declined in the NOR experiment.In order to clarify the molecular mechanisms,the Oxford Nanopore Technologies(ONT)platform was used to perform full-length RNA sequencing.As a result,662 long non-coding RNAs(lncRNAs)and 6895 alternative splicing(AS)events were identified,and the enrichment results of differentially expressed lncRNA target genes and AS genes suggested that the pathways related to cellular autophagy were enriched.The western blotting showed the PI3K/AKT/mTOR signaling pathway was activated,and the results of immunofluorescence also suggested that the HFCS and aspartame intake induced the accumulation of amyloid-βin the hippocampus.All in all,our study,starting from the dimensions of lncRNAs and AS,has deeply analyzed the potential mechanisms underlying the cognitive decline in mice caused by the intake of aspartame and HFCS,and put forward possible and novel insights.展开更多
基金2021 Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province(Cultivation of Science and Technology Innovation for University Students)"Research on Collection and Application of Germplasm Resources of Lingnan Edible-Medicinal Plants in the Implementation of Rural Revitalization Strategy"(pdjh2021b0940).
文摘Edible-medicinal plants play an important role in promoting the pharmaceutical industry and the construction of beautiful countryside.With the development trend of industry promoting rural revitalization,the application of edible-medicinal plants in landscaping is also receiving more and more attention.The present study elaborated the role of edible-medicinal plants and their application principles in landscaping.It stated that the application of edible-medicinal plants in landscaping can improve the preservation and application technology of characteristic edible-medicinal plants in the area of south of the Five Ridges,ensure the sustainable development of edible-medicinal plants and promote the effective connection between poverty alleviation and rural revitalization.
基金Special Foundation for Science and Technology Innovation Strategy of Guangdong Province in 2021(Science and Technology Innovation of College Students Cultivation)(pdjh2021b0940).
文摘The functions of medicinal botanical gardens are introduced firstly,and then the application status and planning principles of medicinal botanical gardens based on the theme of science popularization education are analyzed.Moreover,a typical application case is analyzed and summarized.Constructing a scientific medicinal botanical garden is conducive to increasing people's understanding of medicinal plants,and also meets the requirements of current national policies,thereby generating greater economic and social benefits.
文摘The use of artificial sweeteners is becoming increasingly common.High-fructose corn syrup(HFCS)and aspartame are the two most commonly used sweeteners.It is reported that their consumption was associated with the impairment of cognitive function.However,the specific mechanism whereby HFCS and aspartame diets influence cognitive function is still unclear.Here,we administered 20%HFCS and 50 mg/kg aspartame in drinking water to establish a dietary intervention,and assessed mouse cognitive function using the novel object recognition(NOR)experiment.Results showed that the cognitive function of the mice declined in the NOR experiment.In order to clarify the molecular mechanisms,the Oxford Nanopore Technologies(ONT)platform was used to perform full-length RNA sequencing.As a result,662 long non-coding RNAs(lncRNAs)and 6895 alternative splicing(AS)events were identified,and the enrichment results of differentially expressed lncRNA target genes and AS genes suggested that the pathways related to cellular autophagy were enriched.The western blotting showed the PI3K/AKT/mTOR signaling pathway was activated,and the results of immunofluorescence also suggested that the HFCS and aspartame intake induced the accumulation of amyloid-βin the hippocampus.All in all,our study,starting from the dimensions of lncRNAs and AS,has deeply analyzed the potential mechanisms underlying the cognitive decline in mice caused by the intake of aspartame and HFCS,and put forward possible and novel insights.
