A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is...A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is introduced. Simulation results verify that the protocol is correct and efficient.展开更多
The successful implementation of mass customization lies on reengineeringtechnology and management methods to organize the production. Especially in assembly phase, variousproduct configurations, due-time penalties an...The successful implementation of mass customization lies on reengineeringtechnology and management methods to organize the production. Especially in assembly phase, variousproduct configurations, due-time penalties and order-driven strategy challenge the traditionaloperation and management of assembly lines. The business features and the operation pattern ofassembly line based on mass customization are analyzed. And the research emphatically studiesvarious technologic factors to improve customer satisfaction and their corresponding implementmethods in operating assembly line. In addition, the models are proposed for operating assembly lineunder dynamic process environment in mass customization. A genetic approach is developed to providethe optimal solution to the models. The effectiveness of the proposed approach is evaluated with anindustrial application.展开更多
A mobile robot network is said to be easily scalable to any number of robots if its performance is kept almost fixed after these robots are added or some fail in the network. An interaction dynamics model based on mot...A mobile robot network is said to be easily scalable to any number of robots if its performance is kept almost fixed after these robots are added or some fail in the network. An interaction dynamics model based on motion synchronization is first established. Considering the mobility of mobile robot networks, we propose a relay switched, distributed topology control for the scalable network to drive neMy added robots to the most suitable positions with more neighbors as well as self-heal the blank positions of failed robots, and give a metric of the topology structure for evaluating the performance of network topologies. Then, we prove the stability of motion synchronization with the individual control based on Lyapunov exponent. Finally, the results of simulations have demonstrated the validity of the proposed modeling and control methods.展开更多
A robust H∞ approach to filtering for a class of uncertain linear systems with time-delayed measurement is investigated. The parameter uncertainties are described by real time-varying norm-bounded form. A methodology...A robust H∞ approach to filtering for a class of uncertain linear systems with time-delayed measurement is investigated. The parameter uncertainties are described by real time-varying norm-bounded form. A methodology is developed for designing linear filters such that the filtering process remains robustly stable and the transfer function from the disturbance inputs to error state outputs meets the prescribed H∞-norm upper-bound constraints. The filter can be obtained and parameterized by solving two Riccati equations based on the lemma of robust stability for control system with delay. Simulation example proves the method to be effective and feasible.展开更多
Focused on several problems during robot target tracking, and proposed a new kind of scheme and algorithm for it. The hybrid systematic structure reduces the control complexity and guarantees the tracking effectivenes...Focused on several problems during robot target tracking, and proposed a new kind of scheme and algorithm for it. The hybrid systematic structure reduces the control complexity and guarantees the tracking effectiveness as well as the control stability. The convergence and the feasibility of the algorithm are analyzed and proofed thoroughly. An on-line updating method for navigation coefficient is presented. Finally, the control scheme and proposed algorithm is applied to the real robotic system. The simulation and experimental results show its effectiveness.展开更多
Since the use of drugs is related to the health of the nation, the manufacturing process is usually only one way to ensure the standardization of pharmaceutical technology and the effectiveness of pharmaceutical actio...Since the use of drugs is related to the health of the nation, the manufacturing process is usually only one way to ensure the standardization of pharmaceutical technology and the effectiveness of pharmaceutical action. However, in the process of clinical treatment, according to different situations, the types and types of drugs required are also different, which puts forward a high requirement for pharmaceutical workers. We should have the courage to innovate and break through, and improve the quality of drugs from the selection of API, production plan, technological process and other aspects. In addition, with the rapid development of pharmaceutical technology in China, the recycling of pharmaceutical waste can not be ignored. This plays a vital role in the sustainable development of the pharmaceutical industry.展开更多
The operating temperature of PEMFC stack is a very important control parameter. In operating process, electro-chemical reaction and the humidity of proton exchange membrane vary sensibly with it, the variation of oper...The operating temperature of PEMFC stack is a very important control parameter. In operating process, electro-chemical reaction and the humidity of proton exchange membrane vary sensibly with it, the variation of operating temperature has a significant influence on the output performance and lifespan of fuel cells. The most existing PEMFC mathematical models are too complicated to apply in on-line control process, so it is necessary to find a simple accurate stable control method. In this paper, a novel genetic algorithm (NGA) is presented, which possesses stronger global searching and local optimizing capacities than SGA. NGA is applied to optimize rapidly the weights of neural network according to the population of excellent individuals, neural networks technique is used to establish a self-adjusted control model for PEMFC system. The results of simulation and experiment are given in the end.展开更多
The corona-like spikes or peplomers on the surface of the virion under electronic microscope are the most striking features of coronaviruses. The S (spike) protein is the largest structural protein, with 1,255 amino a...The corona-like spikes or peplomers on the surface of the virion under electronic microscope are the most striking features of coronaviruses. The S (spike) protein is the largest structural protein, with 1,255 amino acids, in the viral genome. Its structure can be divided into three regions: a long N-terminal region in the exterior, a characteristic transmembrane (TM) region, and a short C-terminus in the interior of a virion. We detected fifteen substitutions of nucleotides by comparisons with the seventeen published SARS-CoV genome sequences, eight (53.3%) of which are non-synonymous mutations leading to amino acid alternations with predicted physiochemical changes. The possible antigenic determinants of the S protein are predicted, and the result is confirmed by ELISA (enzyme-linked immunosorbent assay) with synthesized peptides. Another profound finding is that three disulfide bonds are defined at the C-terminus with the N-terminus of the E (envelope) protein, based on the typical sequence and positions, thus establishing the structural connection with these two important structural proteins, if confirmed. Phyloge-netic analysis reveals several conserved regions that might be potent drug targets.展开更多
We report a complete genomic sequence of rare isolates (minor genotype) of the SARS-CoV from SARS patients in Guangdong, China, where the first few cases emerged. The most striking discovery from the isolate is an ext...We report a complete genomic sequence of rare isolates (minor genotype) of the SARS-CoV from SARS patients in Guangdong, China, where the first few cases emerged. The most striking discovery from the isolate is an extra 29-nucleotide sequence located at the nucleotide positions between 27,863 and 27,864 (referred to the complete sequence of BJ01) within an overlapped region composed of BGI-PUP5 (BGI-postulated uncharacterized protein 5) and BGI-PUP6 upstream of the N (nucleocapsid) protein. The discovery of this minor genotype, GD-Ins29, suggests a significant genetic event and differentiates it from the previously reported genotype, the dominant form among all sequenced SARS-CoV isolates. A 17-nt segment of this extra sequence is identical to a segment of the same size in two human mRNA sequences that may interfere with viral genome replication and transcription in the cytosol of the infected cells. It provides a new avenue for the exploration of the virus-host interaction in viral evolution, host pathogenesis, and vaccine development.展开更多
文摘A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is introduced. Simulation results verify that the protocol is correct and efficient.
基金National Natural Science Foundation of China (No.59889505)
文摘The successful implementation of mass customization lies on reengineeringtechnology and management methods to organize the production. Especially in assembly phase, variousproduct configurations, due-time penalties and order-driven strategy challenge the traditionaloperation and management of assembly lines. The business features and the operation pattern ofassembly line based on mass customization are analyzed. And the research emphatically studiesvarious technologic factors to improve customer satisfaction and their corresponding implementmethods in operating assembly line. In addition, the models are proposed for operating assembly lineunder dynamic process environment in mass customization. A genetic approach is developed to providethe optimal solution to the models. The effectiveness of the proposed approach is evaluated with anindustrial application.
基金Supported by the National High Technology Research and Development Programme of China ( No. 2006AA040203 )the National Natural Science Foundation of China (No. 60775062)the Program for New Century Excellent Talents in University (No. NCET-07-0538).
文摘A mobile robot network is said to be easily scalable to any number of robots if its performance is kept almost fixed after these robots are added or some fail in the network. An interaction dynamics model based on motion synchronization is first established. Considering the mobility of mobile robot networks, we propose a relay switched, distributed topology control for the scalable network to drive neMy added robots to the most suitable positions with more neighbors as well as self-heal the blank positions of failed robots, and give a metric of the topology structure for evaluating the performance of network topologies. Then, we prove the stability of motion synchronization with the individual control based on Lyapunov exponent. Finally, the results of simulations have demonstrated the validity of the proposed modeling and control methods.
基金in part by the National Natural Science Foundation under Grrant 69804007,863/CIMS High Technology Foundation 511--845-008 and Science and Technology Program of Shanghai(99QD14012)
文摘A robust H∞ approach to filtering for a class of uncertain linear systems with time-delayed measurement is investigated. The parameter uncertainties are described by real time-varying norm-bounded form. A methodology is developed for designing linear filters such that the filtering process remains robustly stable and the transfer function from the disturbance inputs to error state outputs meets the prescribed H∞-norm upper-bound constraints. The filter can be obtained and parameterized by solving two Riccati equations based on the lemma of robust stability for control system with delay. Simulation example proves the method to be effective and feasible.
文摘Focused on several problems during robot target tracking, and proposed a new kind of scheme and algorithm for it. The hybrid systematic structure reduces the control complexity and guarantees the tracking effectiveness as well as the control stability. The convergence and the feasibility of the algorithm are analyzed and proofed thoroughly. An on-line updating method for navigation coefficient is presented. Finally, the control scheme and proposed algorithm is applied to the real robotic system. The simulation and experimental results show its effectiveness.
文摘Since the use of drugs is related to the health of the nation, the manufacturing process is usually only one way to ensure the standardization of pharmaceutical technology and the effectiveness of pharmaceutical action. However, in the process of clinical treatment, according to different situations, the types and types of drugs required are also different, which puts forward a high requirement for pharmaceutical workers. We should have the courage to innovate and break through, and improve the quality of drugs from the selection of API, production plan, technological process and other aspects. In addition, with the rapid development of pharmaceutical technology in China, the recycling of pharmaceutical waste can not be ignored. This plays a vital role in the sustainable development of the pharmaceutical industry.
文摘The operating temperature of PEMFC stack is a very important control parameter. In operating process, electro-chemical reaction and the humidity of proton exchange membrane vary sensibly with it, the variation of operating temperature has a significant influence on the output performance and lifespan of fuel cells. The most existing PEMFC mathematical models are too complicated to apply in on-line control process, so it is necessary to find a simple accurate stable control method. In this paper, a novel genetic algorithm (NGA) is presented, which possesses stronger global searching and local optimizing capacities than SGA. NGA is applied to optimize rapidly the weights of neural network according to the population of excellent individuals, neural networks technique is used to establish a self-adjusted control model for PEMFC system. The results of simulation and experiment are given in the end.
文摘The corona-like spikes or peplomers on the surface of the virion under electronic microscope are the most striking features of coronaviruses. The S (spike) protein is the largest structural protein, with 1,255 amino acids, in the viral genome. Its structure can be divided into three regions: a long N-terminal region in the exterior, a characteristic transmembrane (TM) region, and a short C-terminus in the interior of a virion. We detected fifteen substitutions of nucleotides by comparisons with the seventeen published SARS-CoV genome sequences, eight (53.3%) of which are non-synonymous mutations leading to amino acid alternations with predicted physiochemical changes. The possible antigenic determinants of the S protein are predicted, and the result is confirmed by ELISA (enzyme-linked immunosorbent assay) with synthesized peptides. Another profound finding is that three disulfide bonds are defined at the C-terminus with the N-terminus of the E (envelope) protein, based on the typical sequence and positions, thus establishing the structural connection with these two important structural proteins, if confirmed. Phyloge-netic analysis reveals several conserved regions that might be potent drug targets.
文摘We report a complete genomic sequence of rare isolates (minor genotype) of the SARS-CoV from SARS patients in Guangdong, China, where the first few cases emerged. The most striking discovery from the isolate is an extra 29-nucleotide sequence located at the nucleotide positions between 27,863 and 27,864 (referred to the complete sequence of BJ01) within an overlapped region composed of BGI-PUP5 (BGI-postulated uncharacterized protein 5) and BGI-PUP6 upstream of the N (nucleocapsid) protein. The discovery of this minor genotype, GD-Ins29, suggests a significant genetic event and differentiates it from the previously reported genotype, the dominant form among all sequenced SARS-CoV isolates. A 17-nt segment of this extra sequence is identical to a segment of the same size in two human mRNA sequences that may interfere with viral genome replication and transcription in the cytosol of the infected cells. It provides a new avenue for the exploration of the virus-host interaction in viral evolution, host pathogenesis, and vaccine development.
