Fluorescence(FL)imaging guided photodynamic therapy(PDT)is becoming highly desirable for personalized therapy and precision medicine.In this study,fluorescent polymer nanoparticles TCPP@PEI/PGA were facilely synthesiz...Fluorescence(FL)imaging guided photodynamic therapy(PDT)is becoming highly desirable for personalized therapy and precision medicine.In this study,fluorescent polymer nanoparticles TCPP@PEI/PGA were facilely synthesized through electrostatic interaction-mediated self-assembly of porphyrins tetra(4-carboxyphenyl)porphine(TCPP)and polyethylenimine(PEI),and subsequent surface modification withγ-poly(glutamic acid)(γ-PGA).TCPP served a dual function as the FL imaging probe and the photosensitizer.The as-prepared TCPP@PEI/PGA nanoparticles showed excellent water-solubility and biocompatibility,while having outstanding capabilities of in vivo bioimaging and~1 O_(2) generation.FL bioimaging of mice and effective killing of CT 26 cells as well as CT 26 tumor-bearing mice upon laser irradiation were successfully demonstrated when using TCPP@PEI/PGA as theranostic nanoprobes.This study provides a simple but robust method to design and synthesize porphyrin-based polymer nanoparticles for theranostics.展开更多
With the acceleration of digitization and informatization,graphic visualization has already become an indispensable tool and medium in modern society.Electroluminescent devices(EL),which refer to certain materials tha...With the acceleration of digitization and informatization,graphic visualization has already become an indispensable tool and medium in modern society.Electroluminescent devices(EL),which refer to certain materials that release photons through internal electron leaps when excited by an electric field,can construct low-cost and flexible multispectral image sensors.In this paper,we propose an alternating current EL device based on a pyramidal conical structure luminescent layer and design a luminescent display image recognition system in combination with a convolutional neural network.The system can recognize the shapes of objects made of different materials while effectively reducing the influence of environmental factors on recognition accuracy,thus achieving a more efficient and reliable image recognition function.Multi-spectral imaging technology provides rich spectral information for the robot,which can provide richer and more comprehensive environment perception capability to meet the needs of diverse dynamic application scenarios.With the significant advantages of EL technology-based image recognition devices,such as high brightness,high contrast,low power consumption,long life,flexibility,and multispectral imaging capability,robots can adapt to complex dynamic environments and achieve higher recognition accuracy and operational efficiency.展开更多
Amorphous gallium oxide(a-Ga_(2)O_(3))has a low carrier concentration and limited mobility,which constrains its application in neuromorphic computing.In this study,Zndoped Ga_(2)O_(3)(ZGO)artificial synaptic devices w...Amorphous gallium oxide(a-Ga_(2)O_(3))has a low carrier concentration and limited mobility,which constrains its application in neuromorphic computing.In this study,Zndoped Ga_(2)O_(3)(ZGO)artificial synaptic devices were fabricated under oxygen-free conditions using radio-frequency magnetron sputtering(RFMS).Compared to undoped Ga_(2)O_(3),the ZGO device exhibited a 106-fold increase in excitatory postsynaptic current under 254 nm illumination,with the response intensity positively correlated with the optical pulse parameters.Under light pulse modulation,the devices demonstrated dynamic behavior transitioning from short-term plasticity to long-term plasticity,including paired-pulse facilitation and the learning-forgetting-relearning process.Furthermore,the electrical and optical energy consumption of synaptic events are as low as 28 fJ and 2 nJ,respectively.The mechanism analysis indicates that the persistent photoconductivity effect in the ZGO thin film is attributed to the abundant oxygen vacancies.A multi-layer perceptron simulation based on ZGO devices achieved a 90.74%accuracy in handwritten digit recognition,and maintained 76.18%accuracy even with 50%noise.Zn doping provides a new material design approach for Ga_(2)O_(3)-based neuromorphic devices,demonstrating potential for future applications in neuromorphic computing.展开更多
In the time of Internet of Things(IoT),alternating current electroluminescence(ACEL)has unique advantages in the fields of smart display and human–computer interaction.However,their reliance on external high-voltage ...In the time of Internet of Things(IoT),alternating current electroluminescence(ACEL)has unique advantages in the fields of smart display and human–computer interaction.However,their reliance on external high-voltage AC power supplies poses challenges in terms of wearability and limits their practical application.This paper proposed an innovative scheme for preparing a feather triboelectric nanogenerator(F-TENG)using recyclable and environmentally friendly material.The highest open-circuit voltage,short-circuit current,and transferred charge of SF6-treated F-TENGs can reach 449 V,63μA,and 152 nC,which enables easy lighting of BaTiO_(3)^(-)doped ACEL devices.Using a human electrical potential,a single-electrode F-TENG is combined with ACEL device for self-powered fingerprint recognition display.These works achieve self-powered flexible wearable ACEL devices,which are not only efficient and portable but also have good application prospects in the human–computer interaction,functional displays,and wearable electronic devices.展开更多
基金The financial support from Shenzhen Basic Research Program(No.JCYJ20210324140004013)Guangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instruments(No.2020B1212060077)Guangdong Natural Science Foundation(No.2020A1515010661)。
文摘Fluorescence(FL)imaging guided photodynamic therapy(PDT)is becoming highly desirable for personalized therapy and precision medicine.In this study,fluorescent polymer nanoparticles TCPP@PEI/PGA were facilely synthesized through electrostatic interaction-mediated self-assembly of porphyrins tetra(4-carboxyphenyl)porphine(TCPP)and polyethylenimine(PEI),and subsequent surface modification withγ-poly(glutamic acid)(γ-PGA).TCPP served a dual function as the FL imaging probe and the photosensitizer.The as-prepared TCPP@PEI/PGA nanoparticles showed excellent water-solubility and biocompatibility,while having outstanding capabilities of in vivo bioimaging and~1 O_(2) generation.FL bioimaging of mice and effective killing of CT 26 cells as well as CT 26 tumor-bearing mice upon laser irradiation were successfully demonstrated when using TCPP@PEI/PGA as theranostic nanoprobes.This study provides a simple but robust method to design and synthesize porphyrin-based polymer nanoparticles for theranostics.
基金the National Key R&D Program of China(2022YFB3606603)Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China(2020ZZ111,2020ZZ113)。
文摘With the acceleration of digitization and informatization,graphic visualization has already become an indispensable tool and medium in modern society.Electroluminescent devices(EL),which refer to certain materials that release photons through internal electron leaps when excited by an electric field,can construct low-cost and flexible multispectral image sensors.In this paper,we propose an alternating current EL device based on a pyramidal conical structure luminescent layer and design a luminescent display image recognition system in combination with a convolutional neural network.The system can recognize the shapes of objects made of different materials while effectively reducing the influence of environmental factors on recognition accuracy,thus achieving a more efficient and reliable image recognition function.Multi-spectral imaging technology provides rich spectral information for the robot,which can provide richer and more comprehensive environment perception capability to meet the needs of diverse dynamic application scenarios.With the significant advantages of EL technology-based image recognition devices,such as high brightness,high contrast,low power consumption,long life,flexibility,and multispectral imaging capability,robots can adapt to complex dynamic environments and achieve higher recognition accuracy and operational efficiency.
基金supported by the National Key Research and Development Program of China (2022YFB3606603)the Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China (2020ZZ111, 2020ZZ113 and 2021ZZ130)the Natural Science Foundation of Fujian Province of China (2024J01281)。
文摘Amorphous gallium oxide(a-Ga_(2)O_(3))has a low carrier concentration and limited mobility,which constrains its application in neuromorphic computing.In this study,Zndoped Ga_(2)O_(3)(ZGO)artificial synaptic devices were fabricated under oxygen-free conditions using radio-frequency magnetron sputtering(RFMS).Compared to undoped Ga_(2)O_(3),the ZGO device exhibited a 106-fold increase in excitatory postsynaptic current under 254 nm illumination,with the response intensity positively correlated with the optical pulse parameters.Under light pulse modulation,the devices demonstrated dynamic behavior transitioning from short-term plasticity to long-term plasticity,including paired-pulse facilitation and the learning-forgetting-relearning process.Furthermore,the electrical and optical energy consumption of synaptic events are as low as 28 fJ and 2 nJ,respectively.The mechanism analysis indicates that the persistent photoconductivity effect in the ZGO thin film is attributed to the abundant oxygen vacancies.A multi-layer perceptron simulation based on ZGO devices achieved a 90.74%accuracy in handwritten digit recognition,and maintained 76.18%accuracy even with 50%noise.Zn doping provides a new material design approach for Ga_(2)O_(3)-based neuromorphic devices,demonstrating potential for future applications in neuromorphic computing.
基金supported by Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China(2021ZZ130)the Natural Science Foundation of Fujian Province,China(2021J01577)。
基金supported by the National Key Research and Development Program of China(No.2021YFB3600402)the National Natural Science Foundation of China(No.62004039)+1 种基金Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China(Nos.2020ZZ111 and 2020ZZ113)the National Natural Science Foundation of Fujian Province,China(No.2021J01577).
文摘In the time of Internet of Things(IoT),alternating current electroluminescence(ACEL)has unique advantages in the fields of smart display and human–computer interaction.However,their reliance on external high-voltage AC power supplies poses challenges in terms of wearability and limits their practical application.This paper proposed an innovative scheme for preparing a feather triboelectric nanogenerator(F-TENG)using recyclable and environmentally friendly material.The highest open-circuit voltage,short-circuit current,and transferred charge of SF6-treated F-TENGs can reach 449 V,63μA,and 152 nC,which enables easy lighting of BaTiO_(3)^(-)doped ACEL devices.Using a human electrical potential,a single-electrode F-TENG is combined with ACEL device for self-powered fingerprint recognition display.These works achieve self-powered flexible wearable ACEL devices,which are not only efficient and portable but also have good application prospects in the human–computer interaction,functional displays,and wearable electronic devices.
