Purpose:To evaluate outcome and toxicity after carbon ion radiotherapy(RT)in skin carcinomas.Patients and Methods:Between November 2006 to September 2008,thirty-three patients with squamous cell carcinoma of the skin(...Purpose:To evaluate outcome and toxicity after carbon ion radiotherapy(RT)in skin carcinomas.Patients and Methods:Between November 2006 to September 2008,thirty-three patients with squamous cell carcinoma of the skin(n=12),basal cell carcinoma of the skin(n=7),malignant skin melanoma(n=6),Bowen’s disease(n=6)and Paget’s disease(n=2)were treated with carbon ion RT at Heavy Ion Research Facility in Lanzhou(HIRFL)within a Phase I trial.Two and three-dimensional conformal irradiation methods realized by the passive beam delivery system and the average RBE of 2.5-3 within the target volume were used in the trial.In 33 patients,there were 9 with failures or recurrences of conventional RT and 14 with recurrences of surgeries.展开更多
文摘Purpose:To evaluate outcome and toxicity after carbon ion radiotherapy(RT)in skin carcinomas.Patients and Methods:Between November 2006 to September 2008,thirty-three patients with squamous cell carcinoma of the skin(n=12),basal cell carcinoma of the skin(n=7),malignant skin melanoma(n=6),Bowen’s disease(n=6)and Paget’s disease(n=2)were treated with carbon ion RT at Heavy Ion Research Facility in Lanzhou(HIRFL)within a Phase I trial.Two and three-dimensional conformal irradiation methods realized by the passive beam delivery system and the average RBE of 2.5-3 within the target volume were used in the trial.In 33 patients,there were 9 with failures or recurrences of conventional RT and 14 with recurrences of surgeries.
