Mammalian cells respond to ionization radiation by sending out extracellular signals to affect non-irradiated neighboring cells,which is referred to as radiation bystander effect.In the present paper,we described a ne...Mammalian cells respond to ionization radiation by sending out extracellular signals to affect non-irradiated neighboring cells,which is referred to as radiation bystander effect.In the present paper,we described a new phenomenon entitled the“rescue effects”,where the bystander cells rescued the irradiated cells through intercellular signal feedback.The effect was observed in both human primary fibroblast(NHLF)and cancer cells(HeLa)using two-cell co-culture systems.展开更多
文摘Mammalian cells respond to ionization radiation by sending out extracellular signals to affect non-irradiated neighboring cells,which is referred to as radiation bystander effect.In the present paper,we described a new phenomenon entitled the“rescue effects”,where the bystander cells rescued the irradiated cells through intercellular signal feedback.The effect was observed in both human primary fibroblast(NHLF)and cancer cells(HeLa)using two-cell co-culture systems.
