Diabetes mellitus entails significant health problems worldwide.The pathogenesis of diabetes is multifactorial,resulting from interactions of both genetic and environmental factors that trigger a complex network of pa...Diabetes mellitus entails significant health problems worldwide.The pathogenesis of diabetes is multifactorial,resulting from interactions of both genetic and environmental factors that trigger a complex network of pathophysiological events,with metabolic and hemodynamic alterations.In this context,inflammation has emerged as a key pathophysiology mechanism.New pathogenic pathways will provide targets for prevention or future treatments.This review will focus on the implications of inflammation in diabetes mellitus,with special attention to inflammatory cytokines.展开更多
基金Supported by Ministerio de Ciencia e Innovación(Instituto de Salud Carlos III-Fondo de Investigación Sanitaria),No.PI07/0870 and No.PI10/576Ministerio de Sanidad y Política Social(Dirección General de Terapias Avanzadas y Trasplante),No.TRA-182+1 种基金Sociedad Espaola de Nefrología y ACINEFResearch activity by Navarro-González JF is supported by Programa de Intensificación de la Actividad Investigadora,ISCIII/Canarias
文摘Diabetes mellitus entails significant health problems worldwide.The pathogenesis of diabetes is multifactorial,resulting from interactions of both genetic and environmental factors that trigger a complex network of pathophysiological events,with metabolic and hemodynamic alterations.In this context,inflammation has emerged as a key pathophysiology mechanism.New pathogenic pathways will provide targets for prevention or future treatments.This review will focus on the implications of inflammation in diabetes mellitus,with special attention to inflammatory cytokines.
