The pathogenic mechanisms of hepatic encephalopathy remain to be elucidated. It has been suggested that a digestive motor disorder could promote the absorpti on of toxins produced within the lumen and thus enhance hep...The pathogenic mechanisms of hepatic encephalopathy remain to be elucidated. It has been suggested that a digestive motor disorder could promote the absorpti on of toxins produced within the lumen and thus enhance hepatic encephalopathy. Aim - To evaluate oro- cecal transit time in cirrhotic patients with and with out hepatic encephalopathy. Methods - Hospitalized patients with alcoholic cir rhosis without encephalopathy and with spontaneous grade I and II encephalopathy were included. Severity of hepatic encephalopathy was assessed clinically and t he Child- Pugh score was used to describe cirrhosis severity. Nine healthy volu nteers constituted a control group. Oro- cecal transit time was measured with t he sulfasalazine test. Results - Twenty- eight patients (mean age 62.5 ± 8. 5 years) were included. Ten had hepatic encephalopathy of unknown cause and 18 w ere free of hepatic encephalopathy. Oro- cecal transit time was significantly l onger in patients with hepatic encephalopathy (641 ± 350 min) compared to pati ents without hepatic encephalopathy (298 ± 96; P< 0.05) and to controls (354 ± 90; P < 0.05). Oro- cecal transit time was comparable for each Child- Pugh score and was not different between the two grades of hepatic encephalopathy. C onclusion Oro- cecal transit time is longer in alcoholic cirrhosis patients wi th hepatic encephalopathy. This digestive motor disorder provides a partial expl anation of hepatic encephalopathy of unknown etiology.展开更多
不只是爱地球,也不只是爱自己和家人的健康,而是两者都爱的生活方式,跨越地理、种族、年龄的限制渗透全球,这就是LOHAS(lifestyles of health and sustainability)。美国社会学者Paul Ray与同事花了15年调查,于1998年写了一本《文化创造...不只是爱地球,也不只是爱自己和家人的健康,而是两者都爱的生活方式,跨越地理、种族、年龄的限制渗透全球,这就是LOHAS(lifestyles of health and sustainability)。美国社会学者Paul Ray与同事花了15年调查,于1998年写了一本《文化创造:5000万人如何改变世界(The Cultural Creative:How 50 Million People are Changing the World)》定义了LOHAS族:一群人在做消费决策时,会考虑到自己与家人的健康和环境责任。展开更多
文摘The pathogenic mechanisms of hepatic encephalopathy remain to be elucidated. It has been suggested that a digestive motor disorder could promote the absorpti on of toxins produced within the lumen and thus enhance hepatic encephalopathy. Aim - To evaluate oro- cecal transit time in cirrhotic patients with and with out hepatic encephalopathy. Methods - Hospitalized patients with alcoholic cir rhosis without encephalopathy and with spontaneous grade I and II encephalopathy were included. Severity of hepatic encephalopathy was assessed clinically and t he Child- Pugh score was used to describe cirrhosis severity. Nine healthy volu nteers constituted a control group. Oro- cecal transit time was measured with t he sulfasalazine test. Results - Twenty- eight patients (mean age 62.5 ± 8. 5 years) were included. Ten had hepatic encephalopathy of unknown cause and 18 w ere free of hepatic encephalopathy. Oro- cecal transit time was significantly l onger in patients with hepatic encephalopathy (641 ± 350 min) compared to pati ents without hepatic encephalopathy (298 ± 96; P< 0.05) and to controls (354 ± 90; P < 0.05). Oro- cecal transit time was comparable for each Child- Pugh score and was not different between the two grades of hepatic encephalopathy. C onclusion Oro- cecal transit time is longer in alcoholic cirrhosis patients wi th hepatic encephalopathy. This digestive motor disorder provides a partial expl anation of hepatic encephalopathy of unknown etiology.
文摘不只是爱地球,也不只是爱自己和家人的健康,而是两者都爱的生活方式,跨越地理、种族、年龄的限制渗透全球,这就是LOHAS(lifestyles of health and sustainability)。美国社会学者Paul Ray与同事花了15年调查,于1998年写了一本《文化创造:5000万人如何改变世界(The Cultural Creative:How 50 Million People are Changing the World)》定义了LOHAS族:一群人在做消费决策时,会考虑到自己与家人的健康和环境责任。
