Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves extract.Methods:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at w...Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves extract.Methods:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at weekly intervals i.e.0,7,14 and 21 in normal and streptozotocin induced diabetic rats.Total cholesterol,triglyceride and HDL-cholesterol were determined in normal and streptozotocin induces diabetic rats by autoanalyser.Glibenclamide was used as a reference drug at a dose of 10 mg/kg.Results:After the oral administration of extracts at doses of 250 mg/kg and 500 mg/kg for three weeks,blood glucose levels and body weights were significantly improved(P【0.01).Daily oral treatment with the extract also resulted in significantly reduction of serum cholesterol and triglycerides.HDL-cholesterol level was found to be improved to(P【0.01).Conclusions:The Cassia siamea leaf extract is useful in controlling blood glucose level as well as improving lipid metabolism and body weight in rats with induced diabetes.展开更多
Objective:To study detail microscopic evaluation and physiochemical analysis of Dillenia indica(D.indica)leaf.Methods:Fresh leaf sample and dried power of the leaf were studied macroscopically and microscopically.Prel...Objective:To study detail microscopic evaluation and physiochemical analysis of Dillenia indica(D.indica)leaf.Methods:Fresh leaf sample and dried power of the leaf were studied macroscopically and microscopically.Preliminary phytochemical investigation of plant material was done.Other WHO recommended parameters for standardizations were also performed.Results:The detail microscopy revealed the presence of anomocytic stomata,unicellular trichome,xylem fibres,calcium oxalate crystals,vascular bundles,etc.Leaf constants such as stomatal number,stomatal index,vein-islet number and veinlet termination numbers were also measured.Physiochemical parameters such as ash values,loss on drying,extractive values,percentage of foreign matters,swelling index,etc.were also determined.Preliminary phytochemical screening showed the presence of steroids,terpenoids,glycosides,fatty acids,flavonoids,phenolic compounds and carbohydrates.Conclusions:The microscopic and physiochemical analysis of the D.indica leaf is useful in standardization for quality,purity and sample identification.展开更多
文摘Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves extract.Methods:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at weekly intervals i.e.0,7,14 and 21 in normal and streptozotocin induced diabetic rats.Total cholesterol,triglyceride and HDL-cholesterol were determined in normal and streptozotocin induces diabetic rats by autoanalyser.Glibenclamide was used as a reference drug at a dose of 10 mg/kg.Results:After the oral administration of extracts at doses of 250 mg/kg and 500 mg/kg for three weeks,blood glucose levels and body weights were significantly improved(P【0.01).Daily oral treatment with the extract also resulted in significantly reduction of serum cholesterol and triglycerides.HDL-cholesterol level was found to be improved to(P【0.01).Conclusions:The Cassia siamea leaf extract is useful in controlling blood glucose level as well as improving lipid metabolism and body weight in rats with induced diabetes.
基金Supported by Career Award for Young Teachers.AICTE.New Delhi.(No.1-51/RID/CA/4/2009-10)
文摘Objective:To study detail microscopic evaluation and physiochemical analysis of Dillenia indica(D.indica)leaf.Methods:Fresh leaf sample and dried power of the leaf were studied macroscopically and microscopically.Preliminary phytochemical investigation of plant material was done.Other WHO recommended parameters for standardizations were also performed.Results:The detail microscopy revealed the presence of anomocytic stomata,unicellular trichome,xylem fibres,calcium oxalate crystals,vascular bundles,etc.Leaf constants such as stomatal number,stomatal index,vein-islet number and veinlet termination numbers were also measured.Physiochemical parameters such as ash values,loss on drying,extractive values,percentage of foreign matters,swelling index,etc.were also determined.Preliminary phytochemical screening showed the presence of steroids,terpenoids,glycosides,fatty acids,flavonoids,phenolic compounds and carbohydrates.Conclusions:The microscopic and physiochemical analysis of the D.indica leaf is useful in standardization for quality,purity and sample identification.
