Carcinosarcoma is an uncommon mixed tumor of the lung. It is composed of a mixture of carcinoma and sarcoma elements. We present a case of 64-year-old male with carcinosarcoma of the lung associated with tuberculosis ...Carcinosarcoma is an uncommon mixed tumor of the lung. It is composed of a mixture of carcinoma and sarcoma elements. We present a case of 64-year-old male with carcinosarcoma of the lung associated with tuberculosis involvement of the same site. The patient was admitted for cough, malaise and fever. Bronchial lavage culture revealed M. tuberculosis. Six months after completion of tuberculosis treatment, the patient was admitted for hemoptysis and headache. CT revealed a solid lesion at the left upper lobe anterior bronchus. Histopathologic examination of the bronchial biopsy specimen revealed carcinosarcoma. Cranial MRI showed a metastatic lesion in the cerebellum which was removed surgically. Four months later, the patient developed bilateral malignant pleural effusions, recurrent cerebellar and skeletal metastases and died in the intensive care unit following intubation for respiratory failure. We describe a case of pulmonary carcinosarcoma occurring at the same localization shortly after successful treatment of tuberculosis with reference to relevant literature.展开更多
Neurodegenerative disorders,including Alzheimer’s disease(AD),Parkinson’s disease(PD),and amyotrophic lateral sclerosis,impose a considerable social and economic burden on society and have dramatic consequences for ...Neurodegenerative disorders,including Alzheimer’s disease(AD),Parkinson’s disease(PD),and amyotrophic lateral sclerosis,impose a considerable social and economic burden on society and have dramatic consequences for individuals and their families.The majority of existing interventions have been found to be capable of only a slight modification of disease progression or to moderately delay significant functional decline in motor,cognitive,or mental domains.展开更多
文摘Carcinosarcoma is an uncommon mixed tumor of the lung. It is composed of a mixture of carcinoma and sarcoma elements. We present a case of 64-year-old male with carcinosarcoma of the lung associated with tuberculosis involvement of the same site. The patient was admitted for cough, malaise and fever. Bronchial lavage culture revealed M. tuberculosis. Six months after completion of tuberculosis treatment, the patient was admitted for hemoptysis and headache. CT revealed a solid lesion at the left upper lobe anterior bronchus. Histopathologic examination of the bronchial biopsy specimen revealed carcinosarcoma. Cranial MRI showed a metastatic lesion in the cerebellum which was removed surgically. Four months later, the patient developed bilateral malignant pleural effusions, recurrent cerebellar and skeletal metastases and died in the intensive care unit following intubation for respiratory failure. We describe a case of pulmonary carcinosarcoma occurring at the same localization shortly after successful treatment of tuberculosis with reference to relevant literature.
文摘Neurodegenerative disorders,including Alzheimer’s disease(AD),Parkinson’s disease(PD),and amyotrophic lateral sclerosis,impose a considerable social and economic burden on society and have dramatic consequences for individuals and their families.The majority of existing interventions have been found to be capable of only a slight modification of disease progression or to moderately delay significant functional decline in motor,cognitive,or mental domains.
