Background:Short bowel syndrome (SBS) is a severe malabsorption caused by bowel loss. Congenital intestinal anomalies (CIA) detectable by prenatal ultrasound as jejunoileal atresia,meconium peritonitis,complicated mec...Background:Short bowel syndrome (SBS) is a severe malabsorption caused by bowel loss. Congenital intestinal anomalies (CIA) detectable by prenatal ultrasound as jejunoileal atresia,meconium peritonitis,complicated meconium ileus,and fetal volvulus can be responsible for SBS. Aims:This study aims to investigate either frequency of SBS or the morbidity in CIA population during the first admission. Material and methods:Records of CIA treated from 1997 to 2003 were reviewed. The prenatal ultrasound findings were correlated with SBS. Student’s t and χ 2 tests were performed to analyze epidemiological data,growth at discharge,sepsis,liver disease,catheter-related complications,motor developmental delay,and hospital stay in CIA with and without SBS. Results:Forty-four CIA:SBS developed in 43% ,ranging from 83% in volvulus to 0% in complicated meconium ileus. Thirty-six prenatal diagnoses:a strong correlation with SBS was observed in isolated dilated bowel (58% ). In SBS neonates,birth weight,gestational age,and growth at discharge were statistically lower,whereas sepsis,motor delay,and hospital stay were statistically higher. Conclusions:Many neonates with CIA detectable by prenatal ultrasound develop SBS. Short bowel syndrome presents a significant higher morbidity. The counseling should stress the frequent association between CIA and SBS as well as the significant morbidity in SBS.展开更多
文摘Background:Short bowel syndrome (SBS) is a severe malabsorption caused by bowel loss. Congenital intestinal anomalies (CIA) detectable by prenatal ultrasound as jejunoileal atresia,meconium peritonitis,complicated meconium ileus,and fetal volvulus can be responsible for SBS. Aims:This study aims to investigate either frequency of SBS or the morbidity in CIA population during the first admission. Material and methods:Records of CIA treated from 1997 to 2003 were reviewed. The prenatal ultrasound findings were correlated with SBS. Student’s t and χ 2 tests were performed to analyze epidemiological data,growth at discharge,sepsis,liver disease,catheter-related complications,motor developmental delay,and hospital stay in CIA with and without SBS. Results:Forty-four CIA:SBS developed in 43% ,ranging from 83% in volvulus to 0% in complicated meconium ileus. Thirty-six prenatal diagnoses:a strong correlation with SBS was observed in isolated dilated bowel (58% ). In SBS neonates,birth weight,gestational age,and growth at discharge were statistically lower,whereas sepsis,motor delay,and hospital stay were statistically higher. Conclusions:Many neonates with CIA detectable by prenatal ultrasound develop SBS. Short bowel syndrome presents a significant higher morbidity. The counseling should stress the frequent association between CIA and SBS as well as the significant morbidity in SBS.
