Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitn...Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitness and physical activity(PA) capacities.The paucity of studies and their conflicting findings prevent a clear understanding and/or substantiation of these limitations.The purpose of this article was to review the measurement,determinants and promotion of physical fitness and PA for youth(i.e.,children and adolescents) with DS. The existing body of research indicates that youth with DS:1) have low cardiovascular and muscular fitness/exercise capacity;2) demonstrate a greater prevalence of overweight and obesity;3) a large proportion do not meet the recommended amount of daily aerobic activity;and 4) their PA likely declines through childhood and into adolescence.Future research should focus on:1) strength testing and training protocols;2) methodologies to determine PA levels;and 3) practical interventions to increase PA.展开更多
Background Left ventricular filling pressure(LVFP)is an important early indicator of heart failure that is more prevalent in Caucasians than Chinese.Exercise-induced change in LVFP may provide more incremental informa...Background Left ventricular filling pressure(LVFP)is an important early indicator of heart failure that is more prevalent in Caucasians than Chinese.Exercise-induced change in LVFP may provide more incremental information to assess dias-tolic function.But it was unknown whether there was difference in LVFP following acute exercise between Caucasians and Chinese.Purpose The purpose of this study was to investigate the change of LVFP following an acute 45-min aerobic exercise in healthy Caucasian and Chinese individuals.Methods Sixty participants(30 Caucasians and 30 Chinese,half was male,respectively)performed an acute bout of aero-bic exercise at 70%of heart rate reserve.Hemodynamics,Left ventricle(LV)morphology and function parameters were measured at baseline,then at 30-min and 60-min post-exercise.Results There was a similar LV ejection fraction,LV fraction shorten,lateral E/eʹand lateral eʹbetween Chinese and Caucasians at baseline.There was a significant race-by-time interaction in lateral E/eʹand lateral eʹbetween Chinese and Caucasians from pre-exercise to 30 min and 60 min after acute aerobic exercise.TheΔE/eʹwas significant correlated with baseline systolic blood pressure.Conclusion The change of LVFP was different between Chinese and Caucasians following acute aerobic exercise.The racial differences may be primarily caused by the changes of LV relaxation following exercise,baseline systolic blood pressure may also contribute to the differences.展开更多
文摘Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitness and physical activity(PA) capacities.The paucity of studies and their conflicting findings prevent a clear understanding and/or substantiation of these limitations.The purpose of this article was to review the measurement,determinants and promotion of physical fitness and PA for youth(i.e.,children and adolescents) with DS. The existing body of research indicates that youth with DS:1) have low cardiovascular and muscular fitness/exercise capacity;2) demonstrate a greater prevalence of overweight and obesity;3) a large proportion do not meet the recommended amount of daily aerobic activity;and 4) their PA likely declines through childhood and into adolescence.Future research should focus on:1) strength testing and training protocols;2) methodologies to determine PA levels;and 3) practical interventions to increase PA.
基金This study was funded by the National Institute of Health of USA(1R01HL093249-01A1)National Education Science Planning Program of China(BLA170225).
文摘Background Left ventricular filling pressure(LVFP)is an important early indicator of heart failure that is more prevalent in Caucasians than Chinese.Exercise-induced change in LVFP may provide more incremental information to assess dias-tolic function.But it was unknown whether there was difference in LVFP following acute exercise between Caucasians and Chinese.Purpose The purpose of this study was to investigate the change of LVFP following an acute 45-min aerobic exercise in healthy Caucasian and Chinese individuals.Methods Sixty participants(30 Caucasians and 30 Chinese,half was male,respectively)performed an acute bout of aero-bic exercise at 70%of heart rate reserve.Hemodynamics,Left ventricle(LV)morphology and function parameters were measured at baseline,then at 30-min and 60-min post-exercise.Results There was a similar LV ejection fraction,LV fraction shorten,lateral E/eʹand lateral eʹbetween Chinese and Caucasians at baseline.There was a significant race-by-time interaction in lateral E/eʹand lateral eʹbetween Chinese and Caucasians from pre-exercise to 30 min and 60 min after acute aerobic exercise.TheΔE/eʹwas significant correlated with baseline systolic blood pressure.Conclusion The change of LVFP was different between Chinese and Caucasians following acute aerobic exercise.The racial differences may be primarily caused by the changes of LV relaxation following exercise,baseline systolic blood pressure may also contribute to the differences.
