In recent years,numerous internet-famous cities have rapidly gained popularity on social media through their unique tourism appeal,attracting massive tourist flows and profoundly impacting local cultural tourism indus...In recent years,numerous internet-famous cities have rapidly gained popularity on social media through their unique tourism appeal,attracting massive tourist flows and profoundly impacting local cultural tourism industries.This paper analyzes the reasons behind these cities’breakout success and explores their development models,offering insights for Hainan’s cultural tourism sector.The study reveals that such urban phenomena primarily stem from four key factors:crafting distinctive city IPs,implementing innovative marketing strategies,providing premium travel experiences,and building community-driven city identities.Drawing from these lessons,Hainan’s cultural tourism industry should leverage its unique cultural resources to develop tourism IPs,adopt new media-driven marketing approaches,enhance service quality,strengthen brand building,and promote high-quality development to boost the region’s tourism visibility and competitiveness.展开更多
When megalopa molting to the first juvenile crab stage,the crabs undergo carcinization morphogenesis.To study the key physiological and morphological processes in carcinization,we performed a comparative transcriptomi...When megalopa molting to the first juvenile crab stage,the crabs undergo carcinization morphogenesis.To study the key physiological and morphological processes in carcinization,we performed a comparative transcriptomic analysis between the cephalothoraxes and the pleons of megalopa and the first juvenile crab stage in Chinese mitten crab.The results reveal that the major physiological and morphological changes in the pleon were related to energy metabolism(oxidative phosphorylation and AMPK pathways),ventral nerve cord fusion(apoptosis-related pathways),and metamorphosis(transcription factors,Hedgehog and Hippo pathways).We also discovered that the key Hox genes abdominal-B and abdominal-A might regulate morphological changes,especially in the degeneration of the fifth pair of pleopods,and ganglion fusion,respectively.Studying the regulatory mechanisms of carcinization may help us better understand the developmental biology of the juvenile crabs.展开更多
Understanding the mechanisms and spatial correlations of crystallographic symmetry breaking in ferroelectric materials is essential to tuning their functional properties.While optical second harmonic generation(SHG)ha...Understanding the mechanisms and spatial correlations of crystallographic symmetry breaking in ferroelectric materials is essential to tuning their functional properties.While optical second harmonic generation(SHG)has long been utilized in ferroelectric studies,its capability for probing complex polar materials has yet to be fully realized.Here,we develop a SHG spectral imaging method implemented on a home-designed laser-scanning SHG microscope,and demonstrate its application for a model system of(K,Na)NbO3 single crystals.Supervised model fitting analysis produces comprehensive information about the polarization vector orientations and relative fractions of constituent domain variants as well as their thermal evolution across the polymorphic phase transitions.Multiple domains and phases are clearly delineated at different temperatures,suggesting the phase competitions in(K,Na)NbO3.Besides,we show that unsupervised matrix decomposition analysis can quickly and faithfully reveal domain configurations without a priori knowledge about specific material systems.The SHG spectral imaging method can be readily extended to other ferroelectric materials with potentials to be further enhanced.展开更多
Over the past two decades,(K_(0.5)Na_(0.5))NbO_(3)(KNN)-based lead-free piezoelectric ceramics have made significant progress.However,attaining a high electrostrain with remarkable temperature stability and minimal hy...Over the past two decades,(K_(0.5)Na_(0.5))NbO_(3)(KNN)-based lead-free piezoelectric ceramics have made significant progress.However,attaining a high electrostrain with remarkable temperature stability and minimal hysteresis under low electric fields has remained a significant challenge.To address this long-standing issue,we have employed a collaborative approach that combines defect engineering,phase engineering,and relaxation engineering.The LKNNS-6BZH ceramic,when sintered at T_(sint)=1170℃,demonstrates an impressive electrostrain with a d_(33) value of 0.276%and 1379 pm·V^(-1)under 20 kV·cm^(-1),which is comparable to or even surpasses that of other lead-free and Pb(Zr,Ti)O_(3)ceramics.Importantly,the electrostrain performance of this ceramic remains stable up to a temperature of 125℃,with the lowest hysteresis observed at 9.73%under 40 kV·cm^(-1).These excellent overall performances are attributed to the presence of defect dipoles involving V′_(A)-V∙∙_(O) and B′_(Nb)-V∙∙O,the coexistence of R-O-T multiphase,and the tuning of the trade-off between long-range ordering and local heterogeneity.This work provides a lead-free alternative for piezoelectric actuators and a paradigm for designing piezoelectric materials with outstanding comprehensive performance under low electric fields.展开更多
To explore the application prospects of an open source artificial intelligence(AI)large language model(LLM)in the medical field,we conducted an analysis from multiple dimensions,including the introduction of LLM,the c...To explore the application prospects of an open source artificial intelligence(AI)large language model(LLM)in the medical field,we conducted an analysis from multiple dimensions,including the introduction of LLM,the classification of model types,and the status quo of the open source ecosystem development.The development of an open source LLM is currently in the rapid expansion phase,and there are many types of models and related tools.After analyzing the advantages and disadvantages of the models,we expounded feasible technical solutions for the application of an LLM in the medical field and made corresponding predictions.At present,LLMs in the medical field are still in the early stages,and there are still many problems related to ethics,technology,legal issues,and medical use.展开更多
基金Haikou Philosophy and Social Science Planning Project in 2025“Research on the Communication Path of Haikou Arcade Culture as City Name Card under the Background of Artificial Intelligence”(2025-ZCKT-100)。
文摘In recent years,numerous internet-famous cities have rapidly gained popularity on social media through their unique tourism appeal,attracting massive tourist flows and profoundly impacting local cultural tourism industries.This paper analyzes the reasons behind these cities’breakout success and explores their development models,offering insights for Hainan’s cultural tourism sector.The study reveals that such urban phenomena primarily stem from four key factors:crafting distinctive city IPs,implementing innovative marketing strategies,providing premium travel experiences,and building community-driven city identities.Drawing from these lessons,Hainan’s cultural tourism industry should leverage its unique cultural resources to develop tourism IPs,adopt new media-driven marketing approaches,enhance service quality,strengthen brand building,and promote high-quality development to boost the region’s tourism visibility and competitiveness.
基金Supported by the National Natural Science Foundation of China(No.31902350)the Research Start-up Fund,and the K.C.Wong Magna Fund of Ningbo University。
文摘When megalopa molting to the first juvenile crab stage,the crabs undergo carcinization morphogenesis.To study the key physiological and morphological processes in carcinization,we performed a comparative transcriptomic analysis between the cephalothoraxes and the pleons of megalopa and the first juvenile crab stage in Chinese mitten crab.The results reveal that the major physiological and morphological changes in the pleon were related to energy metabolism(oxidative phosphorylation and AMPK pathways),ventral nerve cord fusion(apoptosis-related pathways),and metamorphosis(transcription factors,Hedgehog and Hippo pathways).We also discovered that the key Hox genes abdominal-B and abdominal-A might regulate morphological changes,especially in the degeneration of the fifth pair of pleopods,and ganglion fusion,respectively.Studying the regulatory mechanisms of carcinization may help us better understand the developmental biology of the juvenile crabs.
基金supported by National Natural Science Foundation of China(NSFC)under Grants No.52073155 and No.52150092the National Key Basic Research Program of China under Grant No.2020YFA0309100,and by the Project for Introduced Innovation Team in Jinan(2020GXRC037).
文摘Understanding the mechanisms and spatial correlations of crystallographic symmetry breaking in ferroelectric materials is essential to tuning their functional properties.While optical second harmonic generation(SHG)has long been utilized in ferroelectric studies,its capability for probing complex polar materials has yet to be fully realized.Here,we develop a SHG spectral imaging method implemented on a home-designed laser-scanning SHG microscope,and demonstrate its application for a model system of(K,Na)NbO3 single crystals.Supervised model fitting analysis produces comprehensive information about the polarization vector orientations and relative fractions of constituent domain variants as well as their thermal evolution across the polymorphic phase transitions.Multiple domains and phases are clearly delineated at different temperatures,suggesting the phase competitions in(K,Na)NbO3.Besides,we show that unsupervised matrix decomposition analysis can quickly and faithfully reveal domain configurations without a priori knowledge about specific material systems.The SHG spectral imaging method can be readily extended to other ferroelectric materials with potentials to be further enhanced.
基金This study was financially supported by the National Natural Science Foundation of China(Nos.52032007 and 52072028)the National Key R&D Program(No.2022YFB3807400)+1 种基金the Basic Science Center Project of National Natural Science Foundation of China(No.52388201)Tsinghua University-Toyota Research Center.
文摘Over the past two decades,(K_(0.5)Na_(0.5))NbO_(3)(KNN)-based lead-free piezoelectric ceramics have made significant progress.However,attaining a high electrostrain with remarkable temperature stability and minimal hysteresis under low electric fields has remained a significant challenge.To address this long-standing issue,we have employed a collaborative approach that combines defect engineering,phase engineering,and relaxation engineering.The LKNNS-6BZH ceramic,when sintered at T_(sint)=1170℃,demonstrates an impressive electrostrain with a d_(33) value of 0.276%and 1379 pm·V^(-1)under 20 kV·cm^(-1),which is comparable to or even surpasses that of other lead-free and Pb(Zr,Ti)O_(3)ceramics.Importantly,the electrostrain performance of this ceramic remains stable up to a temperature of 125℃,with the lowest hysteresis observed at 9.73%under 40 kV·cm^(-1).These excellent overall performances are attributed to the presence of defect dipoles involving V′_(A)-V∙∙_(O) and B′_(Nb)-V∙∙O,the coexistence of R-O-T multiphase,and the tuning of the trade-off between long-range ordering and local heterogeneity.This work provides a lead-free alternative for piezoelectric actuators and a paradigm for designing piezoelectric materials with outstanding comprehensive performance under low electric fields.
文摘To explore the application prospects of an open source artificial intelligence(AI)large language model(LLM)in the medical field,we conducted an analysis from multiple dimensions,including the introduction of LLM,the classification of model types,and the status quo of the open source ecosystem development.The development of an open source LLM is currently in the rapid expansion phase,and there are many types of models and related tools.After analyzing the advantages and disadvantages of the models,we expounded feasible technical solutions for the application of an LLM in the medical field and made corresponding predictions.At present,LLMs in the medical field are still in the early stages,and there are still many problems related to ethics,technology,legal issues,and medical use.