AIM:To explore and summarize outcomes of a modular surgical approach for the personalized management of angle-closure glaucoma(ACG)secondary to nanophthalmos.METHODS:This was a retrospective interventional case series...AIM:To explore and summarize outcomes of a modular surgical approach for the personalized management of angle-closure glaucoma(ACG)secondary to nanophthalmos.METHODS:This was a retrospective interventional case series involving consecutive patients with nanophthalmos and ACG.All patients were treated with a modular surgical approach tailored to their specific disease characteristics,which included the following surgical combinations:Procedure I[phacoemulsification(phaco)+goniosynechialysis(GSL)],Procedure II[Procedure I+irido-zonulo-hyaloid-vitrectomy(IZHV)],Procedure III[phaco+IZHV+Ahmed glaucoma valve(AGV)implantation],and Procedure IV(Procedure III+scleral window creation).RESULTS:A total of 92 eyes from 62 patients were enrolled,with a median age of 52(range:23-72)y and a median axial length of 19.89(range:14.84-20.99)mm.According to the patients’distinct clinical characteristics,14,26,22,and 30 eyes underwent Procedures I,II,III,and IV,respectively.The median follow-up duration was 13(range:12-36)mo.At the final follow-up visit,all patients achieved a sustained intraocular pressure(IOP)below 21 mm Hg without the administration of anti-glaucoma medications.Postoperative complications included malignant glaucoma(MG,9 eyes),uveal effusion(UE,5 eyes),suprachoroidal hemorrhage(1 eye),fibrin membrane formation(4 eyes),uveitis(1 eye),macular edema(1 eye),and impaired corrected distance visual acuity(CDVA,6 eyes).Univariate analysis revealed that younger age was associated with a higher risk of MG(OR:1.06,P=0.04),UE(OR:1.07,P=0.046),and impaired CDVA(OR:1.11,P=0.02).CONCLUSION:The modular surgical approach yields favorable and consistent clinical prognoses,while reducing the incidence of complications,in the challenging clinical scenario of ACG secondary to nanophthalmos.展开更多
To enhance and actively control terahertz(THz) anisotropy and chirality, we have designed and fabricated a THz composite device with a liquid crystal(LC) layer and Si anisotropic metasurface. By initial anchoring and ...To enhance and actively control terahertz(THz) anisotropy and chirality, we have designed and fabricated a THz composite device with a liquid crystal(LC) layer and Si anisotropic metasurface. By initial anchoring and electrically rotating the spatial orientation of the LC optical axis, the different symmetry relationships are obtained in this hybrid device. When the optical axis of LC is parallel or perpendicular to the optical axis of the Si metasurface, the anisotropy of the device will be enhanced or offset, which leads to a tunable phase-shift range of more than 180°. When there is an angle between the two optical axes, due to the destruction of the mirror symmetry in the LC-Si anisotropic medium, the highest circular dichroism of the device reaches 30 dB in the middle orientation state of the LC optical axis, and the active modulation can be realized by changing the bias electric field on the LC layer. This composite device demonstrates rich characteristics for the feasible manipulation of THz polarization conversion and chiral transmission, which can be applied in THz polarization imaging and chiral spectroscopy.展开更多
基金Supported by National Natural Science Foundation of China(No.82471072)Beijing Municipal Science&Technology Commission(No.Z221100007422057).
文摘AIM:To explore and summarize outcomes of a modular surgical approach for the personalized management of angle-closure glaucoma(ACG)secondary to nanophthalmos.METHODS:This was a retrospective interventional case series involving consecutive patients with nanophthalmos and ACG.All patients were treated with a modular surgical approach tailored to their specific disease characteristics,which included the following surgical combinations:Procedure I[phacoemulsification(phaco)+goniosynechialysis(GSL)],Procedure II[Procedure I+irido-zonulo-hyaloid-vitrectomy(IZHV)],Procedure III[phaco+IZHV+Ahmed glaucoma valve(AGV)implantation],and Procedure IV(Procedure III+scleral window creation).RESULTS:A total of 92 eyes from 62 patients were enrolled,with a median age of 52(range:23-72)y and a median axial length of 19.89(range:14.84-20.99)mm.According to the patients’distinct clinical characteristics,14,26,22,and 30 eyes underwent Procedures I,II,III,and IV,respectively.The median follow-up duration was 13(range:12-36)mo.At the final follow-up visit,all patients achieved a sustained intraocular pressure(IOP)below 21 mm Hg without the administration of anti-glaucoma medications.Postoperative complications included malignant glaucoma(MG,9 eyes),uveal effusion(UE,5 eyes),suprachoroidal hemorrhage(1 eye),fibrin membrane formation(4 eyes),uveitis(1 eye),macular edema(1 eye),and impaired corrected distance visual acuity(CDVA,6 eyes).Univariate analysis revealed that younger age was associated with a higher risk of MG(OR:1.06,P=0.04),UE(OR:1.07,P=0.046),and impaired CDVA(OR:1.11,P=0.02).CONCLUSION:The modular surgical approach yields favorable and consistent clinical prognoses,while reducing the incidence of complications,in the challenging clinical scenario of ACG secondary to nanophthalmos.
基金National Natural Science Foundation of China(61831012,61971242)National Key Research and Development Program of China(2017YFA0701000)Natural Science Foundation of Tianjin City(19JCYBJC16600).
文摘To enhance and actively control terahertz(THz) anisotropy and chirality, we have designed and fabricated a THz composite device with a liquid crystal(LC) layer and Si anisotropic metasurface. By initial anchoring and electrically rotating the spatial orientation of the LC optical axis, the different symmetry relationships are obtained in this hybrid device. When the optical axis of LC is parallel or perpendicular to the optical axis of the Si metasurface, the anisotropy of the device will be enhanced or offset, which leads to a tunable phase-shift range of more than 180°. When there is an angle between the two optical axes, due to the destruction of the mirror symmetry in the LC-Si anisotropic medium, the highest circular dichroism of the device reaches 30 dB in the middle orientation state of the LC optical axis, and the active modulation can be realized by changing the bias electric field on the LC layer. This composite device demonstrates rich characteristics for the feasible manipulation of THz polarization conversion and chiral transmission, which can be applied in THz polarization imaging and chiral spectroscopy.
