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秋水仙碱(0.5mg 2次/d)对稳定性冠状动脉疾病患者高敏C-反应蛋白的影响(独立于阿司匹林和阿托伐他汀) 被引量:9
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作者 Nidorf M. thompson p.l. 罗亮 《世界核心医学期刊文摘(心脏病学分册)》 2007年第8期22-23,共2页
炎性标记物水平升高是稳定性冠状动脉疾病患者未来发生血管事件的预测因素,其中包括高敏C-反应蛋白(hs-CRP)≥2.0m g/L。长期使用小剂量秋水仙碱是缓解炎症的一种安全有效的措施,因此作者进行此项开放性初步研究,以探讨在采用阿司匹林... 炎性标记物水平升高是稳定性冠状动脉疾病患者未来发生血管事件的预测因素,其中包括高敏C-反应蛋白(hs-CRP)≥2.0m g/L。长期使用小剂量秋水仙碱是缓解炎症的一种安全有效的措施,因此作者进行此项开放性初步研究,以探讨在采用阿司匹林联合大剂量阿托伐他汀治疗、hs-CRP≥2.0m g/L的稳定性冠状动脉疾病患者中,秋水仙碱能否显著降低hs-CRP水平。 展开更多
关键词 g 2 秋水仙碱 血管疾病患者 临床结局 基线值 不良反应
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冠状动脉搭桥术后长期无症状存活者的生活质量与普通人群相当
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作者 Bradshaw P.J. Jamrozik K.D. +2 位作者 Gilfillan I.S. thompson p.l. 黎一兵 《世界核心医学期刊文摘(心脏病学分册)》 2006年第6期28-29,共2页
Background: Health- related quality of life(HRQOL) among long- term survivors of coronary artery bypass surgery is an important outcome that has been little studied at the population level. Methods: A postal survey wa... Background: Health- related quality of life(HRQOL) among long- term survivors of coronary artery bypass surgery is an important outcome that has been little studied at the population level. Methods: A postal survey was conducted in 1999 to 2000 in patients 6 to 20 years after coronary artery bypass graft(CABG) surgery in Western Australia. A random stratified sample of 2500 was drawn from 8910 patients who had their first CABG surgery in 1980 to 1993. Health- related quality of life was measured with Short Form 36 and EuroQol visual analogue scale. Results: Response was 82% (n=2061). Health- related quality of life declined with age and was similar for men and women, although scores for women were worse for physical functioning. Compared with Australian population norms, the age- and sex- standardized scores of survivors of CABG were generally worse, mainly in the physical domain. Reported angina at the time of follow- up(33% ), symptoms of heart failure equivalent to New York Heart Association(NYHA) classes II to IV(34% ), and comorbidities such as diabetes and hypertension were associated with poorer HRQOL. For both men and women without angina or heart failure at follow- up,HRQOL was no different from that of the general population. Conclusion: Overall, the quality of life among long- term survivors of CABG is worse than that of the general population, the difference being mainly attributable to recurrent symptoms and comorbidities. Quality of life for those without angina or heart failure at follow- up was equivalent to the population norms, providing an incentive to maximize efforts to abolish angina and ameliorate heart failure symptoms. 展开更多
关键词 健康相关生活质量 CABG术后 冠状动脉搭桥术 长期存活者 普通人群 无症状 HRQOL 视觉模拟评分 年龄增长 澳大利亚
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