The concept of acute-on-chronic liver failure(ACLF)has gained increasing awareness during the last decade.It considers liver cirrhosis as a systemic disease where precipitating events lead to a sudden deterioration,de...The concept of acute-on-chronic liver failure(ACLF)has gained increasing awareness during the last decade.It considers liver cirrhosis as a systemic disease where precipitating events lead to a sudden deterioration,decompensation and extrahepatic organ failures.Disease severity is determined by the number and types of organ failures and patients with ACLF have a distinct and worse prognosis than patients with acute decompensation but not fulfilling ACLF criteria(1-3).展开更多
With great interest we have read the comment of Dr.Khakoo on the recently published CRAFITY score for the prediction of response to anti-programmed death(ligand)1[PD-(L)1]-based immunotherapy in patients with unresect...With great interest we have read the comment of Dr.Khakoo on the recently published CRAFITY score for the prediction of response to anti-programmed death(ligand)1[PD-(L)1]-based immunotherapy in patients with unresectable hepatocellular carcinoma(HCC)(1).展开更多
In a current issue of The Lancet,Spearman and colleagues have provided an extensive global review on hepatitis C virus(HCV)infection,which covers important aspects of epidemiology,natural history,key populations at ri...In a current issue of The Lancet,Spearman and colleagues have provided an extensive global review on hepatitis C virus(HCV)infection,which covers important aspects of epidemiology,natural history,key populations at risk for the infection,aspects on screening and linkage to care and finally current treatment options(1).展开更多
文摘The concept of acute-on-chronic liver failure(ACLF)has gained increasing awareness during the last decade.It considers liver cirrhosis as a systemic disease where precipitating events lead to a sudden deterioration,decompensation and extrahepatic organ failures.Disease severity is determined by the number and types of organ failures and patients with ACLF have a distinct and worse prognosis than patients with acute decompensation but not fulfilling ACLF criteria(1-3).
文摘With great interest we have read the comment of Dr.Khakoo on the recently published CRAFITY score for the prediction of response to anti-programmed death(ligand)1[PD-(L)1]-based immunotherapy in patients with unresectable hepatocellular carcinoma(HCC)(1).
文摘In a current issue of The Lancet,Spearman and colleagues have provided an extensive global review on hepatitis C virus(HCV)infection,which covers important aspects of epidemiology,natural history,key populations at risk for the infection,aspects on screening and linkage to care and finally current treatment options(1).
