Photocatalytic oxidation of toluene to valuable benzaldehyde offers a promising pathway for sustainable production of fine chemicals and pharmaceuticals.In this process,photogenerated holes play a crucial role in C(sp...Photocatalytic oxidation of toluene to valuable benzaldehyde offers a promising pathway for sustainable production of fine chemicals and pharmaceuticals.In this process,photogenerated holes play a crucial role in C(sp^(3))-H bond dissociation.However,the photocatalytic performance of current photocatalysts is often hindered by the low separation and transfer efficiency of photogenerated charges.In this work,we presented a perovskite-based heterostructure via in situ growth of defective WO_(3-x)nanosheets on Cs_(2)AgBiBr_(6)nanoparticles for photocatalytic toluene transformation.In situ Fourier transform infrared spectroscopy tests proved the introduction of oxygen-deficient WO_(3)-xcomponent enhanced the chemisorption of molecular oxygen.The in situ electron paramagnetic resonance and 4-chloro-7-nitro-1,2,3-benzoxadiazole fluorescence measurements further confirmed the presence of oxygen vacancies,and the formation of heterostructure synergistically accelerated the formation of the superoxide radicals and the transfer of photogenerated charge carriers.Under visible light irradiation,Cs_(2)AgBiBr_(6)/WO_(3-x)photocatalyst could effectively oxidize toluene toward benzaldehyde with a conversion rate of 9020μmol g^(-1)h^(-1),which was a 3.5-fold increase over that of the unmodified Cs_(2)AgBiBr_(6).展开更多
Hepatic fibrosis,a degenerative liver lesion,significantly contributes to the deterioration and mortality among patients with chronic liver diseases.The condition arises from various factors including toxins,such as a...Hepatic fibrosis,a degenerative liver lesion,significantly contributes to the deterioration and mortality among patients with chronic liver diseases.The condition arises from various factors including toxins,such as alcohol,infections like different types of viral hepatitis,and metabolic diseases.Currently,there are no effective treatments available for liver fibrosis.Recent research has shown that adiponectin(ADPN)exhibits inhibitory effects on hepatic fibrosis.ADPN,an adipocytokine secreted by mature adipocytes,features receptors that are widely distributed across multiple tissues,especially the liver.In the liver,direct effects of ADPN on liver fibrosis include reducing inflammation and regulating hepatic stellate cell proliferation and migration.And its indirect effects include alleviating hepatic endoplasmic reticulum stress and reducing inflammation in hepatic lobules,thereby mitigating hepatic fibrosis.This review aims to elucidate the regulatory role of ADPN in liver fibrosis,explore how ADPN and its receptors alleviate endoplasmic reticulum stress,summarize ADPN detection methods,and discuss its potential as a novel marker and therapeutic agent in combating hepatic fibrosis.展开更多
基金supported by the National Key Research and Development Program of China(No.2021YFA1600800)the National Natural Science Foundation of China(Nos.22102102,22372102,22101185 and 22402122)+8 种基金Shenzhen Science and Technology Program(No.20231122120657001)the City University of Hong Kong Start-Up Fund(No.9020003)ITFRTH-Global STEM Professorship(No.9446006)Guangdong Basic and Applied Basic Research Foundation(No.2020A1515010982)Research Team Cultivation Program of Shenzhen University(No.2023QNT013)Scientific Foundation for Youth Scholars of Shenzhen University(868-000001032185)Shenzhen Peacock Plan(Nos.20210308299C,RCJC20200714114434086 and 20231121175024001)Shenzhen Key Laboratory of 2D Metamaterials for Information Technology(No.ZDSYS201707271014468)China Postdoctoral Science Foundation(No.2023M742395)
文摘Photocatalytic oxidation of toluene to valuable benzaldehyde offers a promising pathway for sustainable production of fine chemicals and pharmaceuticals.In this process,photogenerated holes play a crucial role in C(sp^(3))-H bond dissociation.However,the photocatalytic performance of current photocatalysts is often hindered by the low separation and transfer efficiency of photogenerated charges.In this work,we presented a perovskite-based heterostructure via in situ growth of defective WO_(3-x)nanosheets on Cs_(2)AgBiBr_(6)nanoparticles for photocatalytic toluene transformation.In situ Fourier transform infrared spectroscopy tests proved the introduction of oxygen-deficient WO_(3)-xcomponent enhanced the chemisorption of molecular oxygen.The in situ electron paramagnetic resonance and 4-chloro-7-nitro-1,2,3-benzoxadiazole fluorescence measurements further confirmed the presence of oxygen vacancies,and the formation of heterostructure synergistically accelerated the formation of the superoxide radicals and the transfer of photogenerated charge carriers.Under visible light irradiation,Cs_(2)AgBiBr_(6)/WO_(3-x)photocatalyst could effectively oxidize toluene toward benzaldehyde with a conversion rate of 9020μmol g^(-1)h^(-1),which was a 3.5-fold increase over that of the unmodified Cs_(2)AgBiBr_(6).
基金supported by the Project of the Jilin Science and Technology Development Program[20220401085YY].
文摘Hepatic fibrosis,a degenerative liver lesion,significantly contributes to the deterioration and mortality among patients with chronic liver diseases.The condition arises from various factors including toxins,such as alcohol,infections like different types of viral hepatitis,and metabolic diseases.Currently,there are no effective treatments available for liver fibrosis.Recent research has shown that adiponectin(ADPN)exhibits inhibitory effects on hepatic fibrosis.ADPN,an adipocytokine secreted by mature adipocytes,features receptors that are widely distributed across multiple tissues,especially the liver.In the liver,direct effects of ADPN on liver fibrosis include reducing inflammation and regulating hepatic stellate cell proliferation and migration.And its indirect effects include alleviating hepatic endoplasmic reticulum stress and reducing inflammation in hepatic lobules,thereby mitigating hepatic fibrosis.This review aims to elucidate the regulatory role of ADPN in liver fibrosis,explore how ADPN and its receptors alleviate endoplasmic reticulum stress,summarize ADPN detection methods,and discuss its potential as a novel marker and therapeutic agent in combating hepatic fibrosis.
