To overcome some of the problems inherent in conventional heating aids such as low gain at high fi'equencies due to acoustic feedback,discomfort in occlusion of the extemal ear canal and so on,implantable middle e...To overcome some of the problems inherent in conventional heating aids such as low gain at high fi'equencies due to acoustic feedback,discomfort in occlusion of the extemal ear canal and so on,implantable middle ear hearing devices(IMEHDs)have been developed over the past two decades.For such kinds of IMEHDs,this paper presents the design of a floating mass piezoelectric actuator using a PMN-30%PT stack as a new type of vibrator.The proposed piezoelectric actuator consists of only three components of a piezoelectric stack,a metal case and a clamp.For the purpose of aiding the design of this actuator,a coupling biomechanics model of human middle ear and the piezoelectric actuator was constructed.This model was built based on a complete set of computerized tomography section images of a healthy volunteer's left ear by reverse engineering technology.The validity of this model was confirmed by comparing the motion of the tympanic membrane and stapes footplate obtained by this model with published experimental measurements on human temporal bones.It is shown that the designed actuator can be implanted on the incus long process by a simple surgical operation,and the stapes footplate displacement by its excitation at 10.5 V root-mean-square(RMS)voltage was equivalent to that from acoustic stimulation at 100 dB sound pressure level(SPL),which is adequate stimulation to the ossicular chain.The corresponding power consumption is 0.04 mW per volt of excitation at 1 kHz,which is low enough for the transducer to be used in an implantable middle ear device.展开更多
Sheet Rb2HgSnS4 was synthesized solvothermally and characterized by X-ray single crystal diffraction. The compound is comprised of sheets with admantane-like [Hg2Sn2S10]8– units. The crystals belong to the space grou...Sheet Rb2HgSnS4 was synthesized solvothermally and characterized by X-ray single crystal diffraction. The compound is comprised of sheets with admantane-like [Hg2Sn2S10]8– units. The crystals belong to the space group C2/c, with the unit cell parameters a=1.1063（2） nm, b=1.1071（2） nm, c=1.5741（3） nm, a=90o, β=100.13（3）o, γ=90o. A reflectance spectroscopy study reveals the nature of the semiconductor with an energy of 2.1 eV for the compound.展开更多
Functional dyspepsia(FD)is a regularly diagnosed clinical gastrointestinal ailment with a high incidence rate that can considerably impact patients’health and quality of life and impose a substantial financial burden...Functional dyspepsia(FD)is a regularly diagnosed clinical gastrointestinal ailment with a high incidence rate that can considerably impact patients’health and quality of life and impose a substantial financial burden.Modern research on the pathophysiology of functional dyspepsia has not thoroughly explained the underlying reasons.The condition does not manifest any significant organ abnormalities,which raises the disease’s difficulty coefficient.Major pathogenic exceptions in FD include gastrointestinal motor dysfunction,gastrointestinal hormone secretion problem,visceral hypersensitivity,and brain-gut axis.Several ion channels have reportedly been implicated in the pathophysiological process of FD.Therefore,it is crucial to comprehend the probable activities of various ion channels in FD.This study focuses on the current state of research on the possible role of several ion channels in the pathogenesis of FD.展开更多
基金supported by National Natural Science Foundation of China(Grant No.10772121)
文摘To overcome some of the problems inherent in conventional heating aids such as low gain at high fi'equencies due to acoustic feedback,discomfort in occlusion of the extemal ear canal and so on,implantable middle ear hearing devices(IMEHDs)have been developed over the past two decades.For such kinds of IMEHDs,this paper presents the design of a floating mass piezoelectric actuator using a PMN-30%PT stack as a new type of vibrator.The proposed piezoelectric actuator consists of only three components of a piezoelectric stack,a metal case and a clamp.For the purpose of aiding the design of this actuator,a coupling biomechanics model of human middle ear and the piezoelectric actuator was constructed.This model was built based on a complete set of computerized tomography section images of a healthy volunteer's left ear by reverse engineering technology.The validity of this model was confirmed by comparing the motion of the tympanic membrane and stapes footplate obtained by this model with published experimental measurements on human temporal bones.It is shown that the designed actuator can be implanted on the incus long process by a simple surgical operation,and the stapes footplate displacement by its excitation at 10.5 V root-mean-square(RMS)voltage was equivalent to that from acoustic stimulation at 100 dB sound pressure level(SPL),which is adequate stimulation to the ossicular chain.The corresponding power consumption is 0.04 mW per volt of excitation at 1 kHz,which is low enough for the transducer to be used in an implantable middle ear device.
基金Supported by the Natural Science Foundations of Inner Mongolia of China(No.20080404MS0212)the Universities Scientific Research Foundations of Inner Mongolia of China(No.NJZY07034)
文摘Sheet Rb2HgSnS4 was synthesized solvothermally and characterized by X-ray single crystal diffraction. The compound is comprised of sheets with admantane-like [Hg2Sn2S10]8– units. The crystals belong to the space group C2/c, with the unit cell parameters a=1.1063（2） nm, b=1.1071（2） nm, c=1.5741（3） nm, a=90o, β=100.13（3）o, γ=90o. A reflectance spectroscopy study reveals the nature of the semiconductor with an energy of 2.1 eV for the compound.
基金“Double first-class”construction project of Mongolian medicine scientific research and innovation team fund(190301)International cooperative scientific and technological innovation project of Mongolian medicine standardization research(MDK2018009)+1 种基金2018 National Civil Affairs Commission-Ministry of Education Mongolian Medicine R&D Engineering Key Laboratory Open Project(MDK2018056)Mongolian Medicine R&D National and Local Joint Engineering Research Center Open Fund Project(MDK2019044).
文摘Functional dyspepsia(FD)is a regularly diagnosed clinical gastrointestinal ailment with a high incidence rate that can considerably impact patients’health and quality of life and impose a substantial financial burden.Modern research on the pathophysiology of functional dyspepsia has not thoroughly explained the underlying reasons.The condition does not manifest any significant organ abnormalities,which raises the disease’s difficulty coefficient.Major pathogenic exceptions in FD include gastrointestinal motor dysfunction,gastrointestinal hormone secretion problem,visceral hypersensitivity,and brain-gut axis.Several ion channels have reportedly been implicated in the pathophysiological process of FD.Therefore,it is crucial to comprehend the probable activities of various ion channels in FD.This study focuses on the current state of research on the possible role of several ion channels in the pathogenesis of FD.
