Objective: to investigate the effect of magnesium sulfate on patients with preeclampsia after elective cesarean section. Methods: 92 patients with preeclampsia during elective cesarean section who were delivered in ou...Objective: to investigate the effect of magnesium sulfate on patients with preeclampsia after elective cesarean section. Methods: 92 patients with preeclampsia during elective cesarean section who were delivered in our hospital from February 2020 to November 2021 were selected as the study objects. According to the odd and even number of the patients admission number, they were divided into two groups: the reference group and the study group, with 46 patients in each group. The reference group was treated with misoprostol, while the study group was treated with magnesium sulfate on the basis of the reference group. The blood pressure, serum TLR4 level, postoperative bleeding, postoperative pain severity score, and the incidence of postoperative adverse reactions were compared between the two groups. Results: there was no significant difference in blood pressure level and serum TLR4 level between the two groups before treatment (P > 0.05). After intervention, the systolic blood pressure, diastolic blood pressure and serum TLR4 level of patients in the study group were lower than those in the reference group, and the difference between the two groups was significant (P < 0.05). The amount of bleeding in different time periods and the total amount of bleeding after intervention in the study group were less than those in the reference group, and the score of postoperative pain severity in the study group was lower than that in the reference group, with statistical significance (P < 0.05). After comparison, the incidence of postoperative adverse reactions in the reference group was significantly higher than that in the study group (P < 0.05). Conclusion: the application of magnesium sulfate in the intervention of patients with pre eclampsia after elective cesarean section has a better effect. It can effectively improve the blood pressure level and serum TLR4 level of patients, reduce the amount of postoperative bleeding of patients, reduce the postoperative pain of patients, and promote the reduction of the incidence of adverse reactions of patients. It has a higher application value.展开更多
文摘Objective: to investigate the effect of magnesium sulfate on patients with preeclampsia after elective cesarean section. Methods: 92 patients with preeclampsia during elective cesarean section who were delivered in our hospital from February 2020 to November 2021 were selected as the study objects. According to the odd and even number of the patients admission number, they were divided into two groups: the reference group and the study group, with 46 patients in each group. The reference group was treated with misoprostol, while the study group was treated with magnesium sulfate on the basis of the reference group. The blood pressure, serum TLR4 level, postoperative bleeding, postoperative pain severity score, and the incidence of postoperative adverse reactions were compared between the two groups. Results: there was no significant difference in blood pressure level and serum TLR4 level between the two groups before treatment (P > 0.05). After intervention, the systolic blood pressure, diastolic blood pressure and serum TLR4 level of patients in the study group were lower than those in the reference group, and the difference between the two groups was significant (P < 0.05). The amount of bleeding in different time periods and the total amount of bleeding after intervention in the study group were less than those in the reference group, and the score of postoperative pain severity in the study group was lower than that in the reference group, with statistical significance (P < 0.05). After comparison, the incidence of postoperative adverse reactions in the reference group was significantly higher than that in the study group (P < 0.05). Conclusion: the application of magnesium sulfate in the intervention of patients with pre eclampsia after elective cesarean section has a better effect. It can effectively improve the blood pressure level and serum TLR4 level of patients, reduce the amount of postoperative bleeding of patients, reduce the postoperative pain of patients, and promote the reduction of the incidence of adverse reactions of patients. It has a higher application value.